Organism | Ratio1 | Gene1 | Name1 | Description1 | Ratio2 | Gene2 | Name2 | Description2 | Cofit | Rank |
Escherichia coli ECRC100 | 1.0 | OKFHMN_20250 | relA | GTP diphosphokinase | 1.0 | OKFHMN_17180 | cysG | siroheme synthase CysG | 0.78 | 10 |
Escherichia coli ECOR27 | 1.00 | NOLOHH_12125 | relA | GTP diphosphokinase | 1.00 | NOLOHH_08980 | cysG | siroheme synthase CysG | low | > 75 |
Escherichia coli ECOR38 | 1.00 | HEPCGN_19500 | relA | GTP diphosphokinase | 1.00 | HEPCGN_16010 | cysG | siroheme synthase CysG | 0.87 | 21 |
Escherichia coli ECRC101 | 1.00 | MCAODC_10775 | relA | GTP diphosphokinase | 1.00 | MCAODC_07710 | cysG | siroheme synthase CysG | 0.53 | 83 |
Escherichia coli ECRC62 | 1.00 | BNILDI_10630 | relA | GTP diphosphokinase | 1.00 | BNILDI_02540 | cysG | siroheme synthase CysG | 0.51 | 36 |
Escherichia coli ECRC98 | 1.00 | JDDGAC_23915 | relA | GTP diphosphokinase | 1.00 | JDDGAC_20810 | cysG | siroheme synthase CysG | 0.71 | 9 |
Escherichia coli BL21 | 1.00 | ECD_02629 | | (p)ppGpp synthetase I/GTP pyrophosphokinase | 1.00 | ECD_03219 | | fused siroheme synthase 1,3-dimethyluroporphyriongen III dehydrogenase and siroheme ferrochelatase/uroporphyrinogen methyltransferase | low | > 61 |
Escherichia coli ECRC102 | 1.00 | NIAGMN_18020 | relA | GTP diphosphokinase | 1.00 | NIAGMN_14950 | cysG | siroheme synthase CysG | — | — |
Escherichia coli BW25113 | 1.00 | b2784 | relA | (p)ppGpp synthetase I/GTP pyrophosphokinase (NCBI) | 1.00 | b3368 | cysG | fused siroheme synthase 1,3-dimethyluroporphyriongen III dehydrogenase and siroheme ferrochelatase/uroporphyrinogen methyltransferase (NCBI) | 0.59 | 1 |
Escherichia coli Nissle 1917 | 1.00 | ECOLIN_RS15515 | | GTP diphosphokinase | 1.00 | ECOLIN_RS19285 | | siroheme synthase CysG | low | > 55 |
Escherichia coli ECRC99 | 1.00 | KEDOAH_07880 | relA | GTP diphosphokinase | 1.00 | KEDOAH_10960 | cysG | siroheme synthase CysG | — | — |
Escherichia fergusonii Becca | 1.00 | EFB2_01133 | | GTP pyrophosphokinase | 1.00 | EFB2_00454 | | Siroheme synthase | low | > 86 |
Escherichia coli HS(pFamp)R (ATCC 700891) | 1.00 | OHPLBJKB_00947 | | GTP pyrophosphokinase | 1.00 | OHPLBJKB_00334 | | Siroheme synthase | low | > 73 |
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 | 0.96 | GFF4837 | | 'GTP pyrophosphokinase (EC 2.7.6.5), (p)ppGpp synthetase I / Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase (EC 3.1.7.2)' transl_table=11 | 0.92 | GFF3700 | | Siroheme synthase / Precorrin-2 oxidase (EC 1.3.1.76) / Sirohydrochlorin ferrochelatase (EC 4.99.1.4) / Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) | low | > 78 |
Klebsiella michiganensis M5al | 0.94 | BWI76_RS22805 | | GTP diphosphokinase | 0.88 | BWI76_RS26055 | | siroheme synthase | 0.55 | 37 |
Enterobacter asburiae PDN3 | 0.94 | EX28DRAFT_2864 | | (p)ppGpp synthetase, RelA/SpoT family | 0.89 | EX28DRAFT_4160 | | uroporphyrin-III C-methyltransferase | low | > 76 |
Enterobacter sp. TBS_079 | 0.93 | MPMX20_03653 | | GTP pyrophosphokinase | 0.89 | MPMX20_04271 | | Siroheme synthase | low | > 85 |
Dickeya dadantii 3937 | 0.87 | DDA3937_RS17015 | | GTP diphosphokinase | 0.50 | DDA3937_RS16930 | | uroporphyrinogen-III C-methyltransferase | low | > 74 |
Dickeya dianthicola 67-19 | 0.87 | HGI48_RS17070 | | GTP diphosphokinase | 0.51 | HGI48_RS17000 | | uroporphyrinogen-III C-methyltransferase | low | > 71 |
Dickeya dianthicola ME23 | 0.87 | DZA65_RS18145 | | GTP diphosphokinase | 0.50 | DZA65_RS18075 | | uroporphyrinogen-III C-methyltransferase | low | > 75 |
Pectobacterium carotovorum WPP14 | 0.86 | HER17_RS04115 | | GTP diphosphokinase | 0.72 | HER17_RS01835 | | siroheme synthase CysG | low | > 75 |
Erwinia tracheiphila SCR3 | 0.86 | LU632_RS06350 | relA | GTP diphosphokinase | 0.53 | LU632_RS06420 | cysG | siroheme synthase CysG | low | > 74 |
Serratia liquefaciens MT49 | 0.85 | IAI46_03600 | | GTP diphosphokinase | 0.71 | IAI46_23670 | | uroporphyrinogen-III C-methyltransferase | low | > 86 |
Rahnella sp. WP5 | 0.85 | EX31_RS07955 | | GTP diphosphokinase | 0.71 | EX31_RS04680 | | uroporphyrinogen-III C-methyltransferase | low | > 89 |
Pantoea sp. MT58 | 0.84 | IAI47_04120 | | GTP diphosphokinase | 0.49 | IAI47_04175 | | uroporphyrinogen-III C-methyltransferase | low | > 76 |
Alteromonas macleodii MIT1002 | 0.53 | MIT1002_00794 | | GTP pyrophosphokinase | 0.45 | MIT1002_00665 | | Siroheme synthase | — | — |
Pseudomonas sp. RS175 | 0.47 | PFR28_03223 | | GTP pyrophosphokinase | 0.49 | PFR28_02603 | | Siroheme synthase | low | > 88 |
Pseudomonas fluorescens GW456-L13 | 0.47 | PfGW456L13_2035 | | GTP pyrophosphokinase (EC 2.7.6.5), (p)ppGpp synthetase I / Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase (EC 3.1.7.2) | 0.48 | PfGW456L13_2656 | | Siroheme synthase / Precorrin-2 oxidase (EC 1.3.1.76) / Sirohydrochlorin ferrochelatase (EC 4.99.1.4) / Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) | 0.39 | 64 |
Pseudomonas fluorescens FW300-N2C3 | 0.47 | AO356_19060 | | (p)ppGpp synthetase | 0.49 | AO356_22200 | | sirohydrochlorin ferrochelatase | low | > 104 |
Pseudomonas fluorescens FW300-N2E3 | 0.47 | AO353_02710 | | (p)ppGpp synthetase | 0.48 | AO353_27625 | | sirohydrochlorin ferrochelatase | — | — |
Pseudomonas fluorescens FW300-N2E2 | 0.47 | Pf6N2E2_5723 | | GTP pyrophosphokinase (EC 2.7.6.5), (p)ppGpp synthetase I / Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase (EC 3.1.7.2) | 0.48 | Pf6N2E2_302 | | Siroheme synthase / Precorrin-2 oxidase (EC 1.3.1.76) / Sirohydrochlorin ferrochelatase (EC 4.99.1.4) / Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) | 0.30 | 49 |
Pseudomonas sp. S08-1 | 0.47 | OH686_18960 | | Inactive (p)ppGpp 3'-pyrophosphohydrolase domain / GTP pyrophosphokinase , (p)ppGpp synthetase I | 0.45 | OH686_00285 | | Precorrin-2 oxidase or Sirohydrochlorin ferrochelatase activity of CysG / Uroporphyrinogen-III methyltransferase | low | > 80 |
Pseudomonas fluorescens SBW25-INTG | 0.47 | PFLU_RS22095 | | GTP diphosphokinase | 0.48 | PFLU_RS18505 | | uroporphyrinogen-III C-methyltransferase | 0.37 | 75 |
Pseudomonas fluorescens SBW25 | 0.47 | PFLU_RS22095 | | GTP diphosphokinase | 0.48 | PFLU_RS18505 | | uroporphyrinogen-III C-methyltransferase | low | > 109 |
Pseudomonas simiae WCS417 | 0.47 | PS417_20150 | | (p)ppGpp synthetase | 0.48 | PS417_16465 | | sirohydrochlorin ferrochelatase | — | — |
Pseudomonas fluorescens FW300-N1B4 | 0.47 | Pf1N1B4_3508 | | GTP pyrophosphokinase (EC 2.7.6.5), (p)ppGpp synthetase I / Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase (EC 3.1.7.2) | 0.49 | Pf1N1B4_4065 | | Siroheme synthase / Precorrin-2 oxidase (EC 1.3.1.76) / Sirohydrochlorin ferrochelatase (EC 4.99.1.4) / Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) | low | > 87 |
Pseudomonas syringae pv. syringae B728a ΔmexB | 0.47 | Psyr_3695 | | RelA/SpoT protein | 0.49 | Psyr_3174 | | uroporphyrinogen-III C-methyltransferase / precorrin-2 dehydrogenase | low | > 86 |
Pseudomonas syringae pv. syringae B728a | 0.47 | Psyr_3695 | | RelA/SpoT protein | 0.49 | Psyr_3174 | | uroporphyrinogen-III C-methyltransferase / precorrin-2 dehydrogenase | 0.39 | 66 |
Pseudomonas putida KT2440 | 0.46 | PP_1656 | | ATP:GTP 3'-pyrophosphotransferase | 0.46 | PP_3999 | | Uroporphyrinogen-III C-methyltransferase/Precorrin-2 dehydrogenase/Sirohydrochlorin ferrochelatase | 0.49 | 9 |
Pseudomonas stutzeri RCH2 | 0.46 | Psest_1640 | | (p)ppGpp synthetase, RelA/SpoT family | 0.50 | Psest_2037 | | uroporphyrin-III C-methyltransferase | low | > 67 |
Kangiella aquimarina DSM 16071 | 0.43 | B158DRAFT_2277 | | (p)ppGpp synthetase, RelA/SpoT family | 0.48 | B158DRAFT_2163 | | uroporphyrin-III C-methyltransferase | low | > 40 |
Dyella japonica UNC79MFTsu3.2 | 0.40 | ABZR86_RS19725 | | bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase | 0.44 | ABZR86_RS05880 | | siroheme synthase CysG | low | > 74 |
Rhodanobacter sp. FW510-T8 | 0.39 | OKGIIK_02170 | relA | GTP diphosphokinase | 0.39 | OKGIIK_05980 | cysG | siroheme synthase CysG | low | > 52 |
Rhodanobacter denitrificans FW104-10B01 | 0.39 | LRK54_RS12725 | | bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase | 0.38 | LRK54_RS00910 | | siroheme synthase CysG | low | > 59 |
Rhodanobacter denitrificans MT42 | 0.39 | LRK55_RS12430 | | bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase | 0.37 | LRK55_RS00685 | | siroheme synthase CysG | low | > 63 |
Acinetobacter radioresistens SK82 | 0.36 | MPMX26_00539 | | GTP pyrophosphokinase | 0.45 | MPMX26_00706 | | Siroheme synthase | — | — |
Lysobacter sp. OAE881 | 0.34 | ABIE51_RS05170 | | bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase | 0.43 | ABIE51_RS15855 | | siroheme synthase CysG | 0.84 | 21 |
Castellaniella sp019104865 MT123 | 0.33 | ABCV34_RS08440 | | bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase | 0.39 | ABCV34_RS00210 | | siroheme synthase CysG | 0.86 | 11 |
Not shown: 24 genomes with orthologs for OKFHMN_20250 only; 9 genomes with orthologs for OKFHMN_17180 only