Conservation of cofitness between OKFHMN_20250 and OKFHMN_17180 in Escherichia coli ECRC100

47 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Escherichia coli ECRC100 1.0 OKFHMN_20250 relA GTP diphosphokinase 1.0 OKFHMN_17180 cysG siroheme synthase CysG 0.78 10
Escherichia coli ECOR27 1.00 NOLOHH_12125 relA GTP diphosphokinase 1.00 NOLOHH_08980 cysG siroheme synthase CysG low > 75
Escherichia coli ECOR38 1.00 HEPCGN_19500 relA GTP diphosphokinase 1.00 HEPCGN_16010 cysG siroheme synthase CysG 0.87 21
Escherichia coli ECRC101 1.00 MCAODC_10775 relA GTP diphosphokinase 1.00 MCAODC_07710 cysG siroheme synthase CysG 0.53 83
Escherichia coli ECRC62 1.00 BNILDI_10630 relA GTP diphosphokinase 1.00 BNILDI_02540 cysG siroheme synthase CysG 0.51 36
Escherichia coli ECRC98 1.00 JDDGAC_23915 relA GTP diphosphokinase 1.00 JDDGAC_20810 cysG siroheme synthase CysG 0.71 9
Escherichia coli BL21 1.00 ECD_02629 (p)ppGpp synthetase I/GTP pyrophosphokinase 1.00 ECD_03219 fused siroheme synthase 1,3-dimethyluroporphyriongen III dehydrogenase and siroheme ferrochelatase/uroporphyrinogen methyltransferase low > 61
Escherichia coli ECRC102 1.00 NIAGMN_18020 relA GTP diphosphokinase 1.00 NIAGMN_14950 cysG siroheme synthase CysG
Escherichia coli BW25113 1.00 b2784 relA (p)ppGpp synthetase I/GTP pyrophosphokinase (NCBI) 1.00 b3368 cysG fused siroheme synthase 1,3-dimethyluroporphyriongen III dehydrogenase and siroheme ferrochelatase/uroporphyrinogen methyltransferase (NCBI) 0.59 1
Escherichia coli Nissle 1917 1.00 ECOLIN_RS15515 GTP diphosphokinase 1.00 ECOLIN_RS19285 siroheme synthase CysG low > 55
Escherichia coli ECRC99 1.00 KEDOAH_07880 relA GTP diphosphokinase 1.00 KEDOAH_10960 cysG siroheme synthase CysG
Escherichia fergusonii Becca 1.00 EFB2_01133 GTP pyrophosphokinase 1.00 EFB2_00454 Siroheme synthase low > 86
Escherichia coli HS(pFamp)R (ATCC 700891) 1.00 OHPLBJKB_00947 GTP pyrophosphokinase 1.00 OHPLBJKB_00334 Siroheme synthase low > 73
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.96 GFF4837 'GTP pyrophosphokinase (EC 2.7.6.5), (p)ppGpp synthetase I / Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase (EC 3.1.7.2)' transl_table=11 0.92 GFF3700 Siroheme synthase / Precorrin-2 oxidase (EC 1.3.1.76) / Sirohydrochlorin ferrochelatase (EC 4.99.1.4) / Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) low > 78
Klebsiella michiganensis M5al 0.94 BWI76_RS22805 GTP diphosphokinase 0.88 BWI76_RS26055 siroheme synthase 0.55 37
Enterobacter asburiae PDN3 0.94 EX28DRAFT_2864 (p)ppGpp synthetase, RelA/SpoT family 0.89 EX28DRAFT_4160 uroporphyrin-III C-methyltransferase low > 76
Enterobacter sp. TBS_079 0.93 MPMX20_03653 GTP pyrophosphokinase 0.89 MPMX20_04271 Siroheme synthase low > 85
Dickeya dadantii 3937 0.87 DDA3937_RS17015 GTP diphosphokinase 0.50 DDA3937_RS16930 uroporphyrinogen-III C-methyltransferase low > 74
Dickeya dianthicola 67-19 0.87 HGI48_RS17070 GTP diphosphokinase 0.51 HGI48_RS17000 uroporphyrinogen-III C-methyltransferase low > 71
Dickeya dianthicola ME23 0.87 DZA65_RS18145 GTP diphosphokinase 0.50 DZA65_RS18075 uroporphyrinogen-III C-methyltransferase low > 75
Pectobacterium carotovorum WPP14 0.86 HER17_RS04115 GTP diphosphokinase 0.72 HER17_RS01835 siroheme synthase CysG low > 75
Erwinia tracheiphila SCR3 0.86 LU632_RS06350 relA GTP diphosphokinase 0.53 LU632_RS06420 cysG siroheme synthase CysG low > 74
Serratia liquefaciens MT49 0.85 IAI46_03600 GTP diphosphokinase 0.71 IAI46_23670 uroporphyrinogen-III C-methyltransferase low > 86
Rahnella sp. WP5 0.85 EX31_RS07955 GTP diphosphokinase 0.71 EX31_RS04680 uroporphyrinogen-III C-methyltransferase low > 89
Pantoea sp. MT58 0.84 IAI47_04120 GTP diphosphokinase 0.49 IAI47_04175 uroporphyrinogen-III C-methyltransferase low > 76
Alteromonas macleodii MIT1002 0.53 MIT1002_00794 GTP pyrophosphokinase 0.45 MIT1002_00665 Siroheme synthase
Pseudomonas sp. RS175 0.47 PFR28_03223 GTP pyrophosphokinase 0.49 PFR28_02603 Siroheme synthase low > 88
Pseudomonas fluorescens GW456-L13 0.47 PfGW456L13_2035 GTP pyrophosphokinase (EC 2.7.6.5), (p)ppGpp synthetase I / Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase (EC 3.1.7.2) 0.48 PfGW456L13_2656 Siroheme synthase / Precorrin-2 oxidase (EC 1.3.1.76) / Sirohydrochlorin ferrochelatase (EC 4.99.1.4) / Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) 0.39 64
Pseudomonas fluorescens FW300-N2C3 0.47 AO356_19060 (p)ppGpp synthetase 0.49 AO356_22200 sirohydrochlorin ferrochelatase low > 104
Pseudomonas fluorescens FW300-N2E3 0.47 AO353_02710 (p)ppGpp synthetase 0.48 AO353_27625 sirohydrochlorin ferrochelatase
Pseudomonas fluorescens FW300-N2E2 0.47 Pf6N2E2_5723 GTP pyrophosphokinase (EC 2.7.6.5), (p)ppGpp synthetase I / Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase (EC 3.1.7.2) 0.48 Pf6N2E2_302 Siroheme synthase / Precorrin-2 oxidase (EC 1.3.1.76) / Sirohydrochlorin ferrochelatase (EC 4.99.1.4) / Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) 0.30 49
Pseudomonas sp. S08-1 0.47 OH686_18960 Inactive (p)ppGpp 3'-pyrophosphohydrolase domain / GTP pyrophosphokinase , (p)ppGpp synthetase I 0.45 OH686_00285 Precorrin-2 oxidase or Sirohydrochlorin ferrochelatase activity of CysG / Uroporphyrinogen-III methyltransferase low > 80
Pseudomonas fluorescens SBW25-INTG 0.47 PFLU_RS22095 GTP diphosphokinase 0.48 PFLU_RS18505 uroporphyrinogen-III C-methyltransferase 0.37 75
Pseudomonas fluorescens SBW25 0.47 PFLU_RS22095 GTP diphosphokinase 0.48 PFLU_RS18505 uroporphyrinogen-III C-methyltransferase low > 109
Pseudomonas simiae WCS417 0.47 PS417_20150 (p)ppGpp synthetase 0.48 PS417_16465 sirohydrochlorin ferrochelatase
Pseudomonas fluorescens FW300-N1B4 0.47 Pf1N1B4_3508 GTP pyrophosphokinase (EC 2.7.6.5), (p)ppGpp synthetase I / Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase (EC 3.1.7.2) 0.49 Pf1N1B4_4065 Siroheme synthase / Precorrin-2 oxidase (EC 1.3.1.76) / Sirohydrochlorin ferrochelatase (EC 4.99.1.4) / Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) low > 87
Pseudomonas syringae pv. syringae B728a ΔmexB 0.47 Psyr_3695 RelA/SpoT protein 0.49 Psyr_3174 uroporphyrinogen-III C-methyltransferase / precorrin-2 dehydrogenase low > 86
Pseudomonas syringae pv. syringae B728a 0.47 Psyr_3695 RelA/SpoT protein 0.49 Psyr_3174 uroporphyrinogen-III C-methyltransferase / precorrin-2 dehydrogenase 0.39 66
Pseudomonas putida KT2440 0.46 PP_1656 ATP:GTP 3'-pyrophosphotransferase 0.46 PP_3999 Uroporphyrinogen-III C-methyltransferase/Precorrin-2 dehydrogenase/Sirohydrochlorin ferrochelatase 0.49 9
Pseudomonas stutzeri RCH2 0.46 Psest_1640 (p)ppGpp synthetase, RelA/SpoT family 0.50 Psest_2037 uroporphyrin-III C-methyltransferase low > 67
Kangiella aquimarina DSM 16071 0.43 B158DRAFT_2277 (p)ppGpp synthetase, RelA/SpoT family 0.48 B158DRAFT_2163 uroporphyrin-III C-methyltransferase low > 40
Dyella japonica UNC79MFTsu3.2 0.40 ABZR86_RS19725 bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase 0.44 ABZR86_RS05880 siroheme synthase CysG low > 74
Rhodanobacter sp. FW510-T8 0.39 OKGIIK_02170 relA GTP diphosphokinase 0.39 OKGIIK_05980 cysG siroheme synthase CysG low > 52
Rhodanobacter denitrificans FW104-10B01 0.39 LRK54_RS12725 bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase 0.38 LRK54_RS00910 siroheme synthase CysG low > 59
Rhodanobacter denitrificans MT42 0.39 LRK55_RS12430 bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase 0.37 LRK55_RS00685 siroheme synthase CysG low > 63
Acinetobacter radioresistens SK82 0.36 MPMX26_00539 GTP pyrophosphokinase 0.45 MPMX26_00706 Siroheme synthase
Lysobacter sp. OAE881 0.34 ABIE51_RS05170 bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase 0.43 ABIE51_RS15855 siroheme synthase CysG 0.84 21
Castellaniella sp019104865 MT123 0.33 ABCV34_RS08440 bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase 0.39 ABCV34_RS00210 siroheme synthase CysG 0.86 11

Not shown: 24 genomes with orthologs for OKFHMN_20250 only; 9 genomes with orthologs for OKFHMN_17180 only