| Organism | Ratio1 | Gene1 | Name1 | Description1 | Ratio2 | Gene2 | Name2 | Description2 | Cofit | Rank |
| Vibrio cholerae E7946 ATCC 55056 | 1.0 | CSW01_05900 | | carboxy-S-adenosyl-L-methionine synthase CmoA | 1.0 | CSW01_19025 | | LysR family transcriptional regulator | 0.52 | 2 |
| Pantoea agglomerans CFBP13505 P0401 | 0.76 | PagCFBP13505_RS02290 | | carboxy-S-adenosyl-L-methionine synthase CmoA | 0.27 | PagCFBP13505_RS08890 | | LysR family transcriptional regulator | low | > 74 |
| Serratia liquefaciens MT49 | 0.76 | IAI46_14670 | | carboxy-S-adenosyl-L-methionine synthase CmoA | 0.55 | IAI46_20610 | | LysR family transcriptional regulator | — | — |
| Pantoea sp. MT58 | 0.75 | IAI47_08410 | | carboxy-S-adenosyl-L-methionine synthase CmoA | 0.28 | IAI47_20580 | | LysR family transcriptional regulator | low | > 76 |
| Rahnella sp. WP5 | 0.75 | EX31_RS17285 | | carboxy-S-adenosyl-L-methionine synthase CmoA | 0.30 | EX31_RS16730 | | LysR family transcriptional regulator | low | > 89 |
| Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 | 0.75 | GFF1651 | | tRNA (uridine-5-oxyacetic acid methyl ester) 34 synthase | 0.25 | GFF2141 | | LysR family transcriptional regulator QseA | low | > 78 |
| Erwinia amylovora T8 | 0.74 | OLJFJH_12820 | | carboxy-S-adenosyl-L-methionine synthase CmoA | 0.25 | OLJFJH_06945 | | HTH-type transcriptional activator AaeR | low | > 58 |
| Escherichia coli BW25113 | 0.74 | b1870 | yecO | predicted methyltransferase (NCBI) | 0.25 | b3521 | yhjC | predicted DNA-binding transcriptional regulator (RefSeq) | — | — |
| Escherichia coli BL21 | 0.74 | ECD_01841 | | carboxy-SAM synthase | 0.25 | ECD_03369 | | LysR family putative transcriptional regulator | low | > 61 |
| Escherichia coli HS(pFamp)R (ATCC 700891) | 0.74 | OHPLBJKB_01858 | | Carboxy-S-adenosyl-L-methionine synthase | 0.25 | OHPLBJKB_00181 | | HTH-type transcriptional regulator DmlR | low | > 74 |
| Escherichia coli ECOR27 | 0.74 | NOLOHH_16670 | cmoA | carboxy-S-adenosyl-L-methionine synthase CmoA | 0.25 | NOLOHH_08195 | yhjC | Uncharacterized HTH-type transcriptional regulator YhjC | low | > 76 |
| Escherichia coli Nissle 1917 | 0.74 | ECOLIN_RS10695 | | carboxy-S-adenosyl-L-methionine synthase CmoA | 0.25 | ECOLIN_RS20140 | | LysR family transcriptional regulator | — | — |
| Escherichia coli ECRC99 | 0.74 | KEDOAH_01880 | cmoA | carboxy-S-adenosyl-L-methionine synthase CmoA | 0.25 | KEDOAH_10390 | aaeR | HTH-type transcriptional activator AaeR | — | — |
| Escherichia coli ECRC102 | 0.74 | NIAGMN_01835 | cmoA | carboxy-S-adenosyl-L-methionine synthase CmoA | 0.25 | NIAGMN_15520 | aaeR | HTH-type transcriptional activator AaeR | low | > 80 |
| Escherichia coli ECRC62 | 0.74 | BNILDI_15460 | cmoA | carboxy-S-adenosyl-L-methionine synthase CmoA | 0.25 | BNILDI_03360 | yhjC | Uncharacterized HTH-type transcriptional regulator YhjC | low | > 75 |
| Escherichia coli ECRC98 | 0.74 | JDDGAC_00800 | cmoA | carboxy-S-adenosyl-L-methionine synthase CmoA | 0.25 | JDDGAC_21385 | aaeR | HTH-type transcriptional activator AaeR | low | > 87 |
| Escherichia coli ECOR38 | 0.74 | HEPCGN_04635 | cmoA | carboxy-S-adenosyl-L-methionine synthase CmoA | 0.25 | HEPCGN_15135 | yhjC | Uncharacterized HTH-type transcriptional regulator YhjC | low | > 88 |
| Escherichia coli ECRC100 | 0.74 | OKFHMN_26225 | cmoA | carboxy-S-adenosyl-L-methionine synthase CmoA | 0.25 | OKFHMN_17760 | aaeR | HTH-type transcriptional activator AaeR | low | > 79 |
| Escherichia coli ECRC101 | 0.74 | MCAODC_19180 | cmoA | carboxy-S-adenosyl-L-methionine synthase CmoA | 0.25 | MCAODC_08280 | aaeR | HTH-type transcriptional activator AaeR | low | > 87 |
| Klebsiella pneumoniae MKP103 | 0.74 | KDGMDA_25455 | | carboxy-S-adenosyl-L-methionine synthase CmoA | 0.28 | KDGMDA_05040 | | LysR family transcriptional regulator | low | > 95 |
| Escherichia fergusonii Becca | 0.74 | EFB2_02072 | | Carboxy-S-adenosyl-L-methionine synthase | 0.25 | EFB2_00287 | | HTH-type transcriptional regulator DmlR | low | > 86 |
| Klebsiella michiganensis M5al | 0.73 | BWI76_RS18190 | | carboxy-S-adenosyl-L-methionine synthase CmoA | 0.27 | BWI76_RS27965 | | LysR family transcriptional regulator | low | > 92 |
| Dickeya dianthicola 67-19 | 0.71 | HGI48_RS10070 | | carboxy-S-adenosyl-L-methionine synthase CmoA | 0.26 | HGI48_RS19010 | | LysR family transcriptional regulator | low | > 71 |
| Shewanella sp. ANA-3 | 0.65 | Shewana3_1951 | | putative methyltransferase (RefSeq) | 0.37 | Shewana3_3800 | | LysR family transcriptional regulator (RefSeq) | low | > 73 |
| Shewanella oneidensis MR-1 | 0.65 | SO2435 | | methyltransferase, putative (NCBI ptt file) | 0.38 | SO0369 | | transcriptional regulator, LysR family (NCBI ptt file) | low | > 76 |
| Pseudomonas sp. BP01 | 0.60 | JOY50_RS14735 | cmoA | carboxy-S-adenosyl-L-methionine synthase CmoA | 0.32 | JOY50_RS04745 | | LysR family transcriptional regulator | low | > 84 |
| Pseudomonas putida KT2440 | 0.60 | PP_1441 | | tRNA (cmo5U34)-methyltransferase | 0.32 | PP_3811 | | Transcriptional regulator, LysR family | low | > 96 |
| Pseudomonas fluorescens SBW25-INTG | 0.60 | PFLU_RS05295 | | carboxy-S-adenosyl-L-methionine synthase CmoA | 0.33 | PFLU_RS18050 | | LysR family transcriptional regulator | low | > 109 |
| Pseudomonas fluorescens SBW25 | 0.60 | PFLU_RS05295 | | carboxy-S-adenosyl-L-methionine synthase CmoA | 0.33 | PFLU_RS18050 | | LysR family transcriptional regulator | low | > 109 |
| Pseudomonas simiae WCS417 | 0.59 | PS417_05225 | | tRNA methyltransferase | 0.32 | PS417_16085 | | LysR family transcriptional regulator | low | > 88 |
| Pseudomonas sp. DMC3 | 0.59 | GFF4315 | | Carboxy-S-adenosyl-L-methionine synthase | 0.32 | GFF943 | | HTH-type transcriptional regulator DmlR | low | > 89 |
| Pseudomonas fluorescens FW300-N1B4 | 0.59 | Pf1N1B4_825 | | tRNA (uridine-5-oxyacetic acid methyl ester) 34 synthase | 0.32 | Pf1N1B4_5905 | | Transcriptional regulator, LysR family | low | > 87 |
| Pseudomonas fluorescens FW300-N2E3 | 0.59 | AO353_16020 | | tRNA (cmo5U34)-methyltransferase | 0.31 | AO353_22295 | | LysR family transcriptional regulator | low | > 101 |
| Pseudomonas lactucae CFBP13502 | 0.59 | GEMAOFIL_01251 | | Carboxy-S-adenosyl-L-methionine synthase | 0.32 | GEMAOFIL_02593 | | HTH-type transcriptional regulator DmlR | 0.79 | 2 |
| Pseudomonas fluorescens FW300-N2C3 | 0.59 | AO356_06445 | | tRNA (cmo5U34)-methyltransferase | 0.31 | AO356_21990 | | LysR family transcriptional regulator | low | > 104 |
| Pseudomonas fluorescens FW300-N2E2 | 0.59 | Pf6N2E2_3157 | | tRNA (uridine-5-oxyacetic acid methyl ester) 34 synthase | 0.32 | Pf6N2E2_259 | | Transcriptional regulator, LysR family | low | > 103 |
| Pseudomonas orientalis W4I3 | 0.58 | QF045_RS08215 | | carboxy-S-adenosyl-L-methionine synthase CmoA | 0.32 | QF045_RS13895 | | LysR family transcriptional regulator | low | > 93 |
| Pseudomonas segetis P6 | 0.58 | MPMX49_01415 | | Carboxy-S-adenosyl-L-methionine synthase | 0.29 | MPMX49_03437 | | HTH-type transcriptional regulator DmlR | low | > 75 |
| Pseudomonas sp. S08-1 | 0.58 | OH686_05370 | | tRNA (cmo5U34)-methyltransferase | 0.31 | OH686_18145 | | Transcriptional regulator, LysR family, in formaldehyde detoxification operon | low | > 80 |
| Pseudomonas aeruginosa MRSN321 | 0.58 | DY961_RS08625 | cmoA;inference=COORDINATES | carboxy-S-adenosyl-L-methionine synthase CmoA | 0.31 | DY961_RS18625 | | LysR family transcriptional regulator | low | > 100 |
| Pseudomonas syringae pv. syringae B728a ΔmexB | 0.58 | Psyr_3946 | | Proteobacterial methyltransferase | 0.32 | Psyr_2951 | | transcriptional regulator, LysR family | low | > 86 |
| Pseudomonas fluorescens GW456-L13 | 0.58 | PfGW456L13_4811 | | tRNA (uridine-5-oxyacetic acid methyl ester) 34 synthase | 0.32 | PfGW456L13_3857 | | Transcriptional regulator, LysR family | low | > 87 |
| Pseudomonas syringae pv. syringae B728a | 0.58 | Psyr_3946 | | Proteobacterial methyltransferase | 0.32 | Psyr_2951 | | transcriptional regulator, LysR family | low | > 86 |
| Pseudomonas aeruginosa PUPa3 | 0.58 | DQ20_RS44225 | cmoA;inference=COORDINATES | carboxy-S-adenosyl-L-methionine synthase CmoA | 0.31 | DQ20_RS59835 | | LysR family transcriptional regulator | low | > 101 |
| Pseudomonas stutzeri RCH2 | 0.58 | Psest_3084 | | methyltransferase, putative | 0.31 | Psest_2163 | | Transcriptional regulator | 0.13 | 51 |
| Pseudomonas aeruginosa PA14 | 0.57 | IKLFDK_03330 | | carboxy-S-adenosyl-L-methionine synthase CmoA | 0.31 | IKLFDK_11955 | | LysR family transcriptional regulator | low | > 98 |
| Pseudomonas sp. RS175 | 0.57 | PFR28_00319 | | Carboxy-S-adenosyl-L-methionine synthase | 0.30 | PFR28_00531 | | HTH-type transcriptional regulator DmlR | low | > 88 |
| Alteromonas macleodii MIT1002 | 0.54 | MIT1002_02225 | | tRNA (cmo5U34)-methyltransferase | 0.76 | MIT1002_03329 | | D-malate degradation protein R | low | > 70 |
| Marinobacter adhaerens HP15 | 0.51 | HP15_2492 | | methyltransferase | 0.31 | HP15_936 | | transcriptional regulator, LysR family protein | low | > 73 |
| Magnetospirillum magneticum AMB-1 | 0.11 | AMB_RS20665 | | class I SAM-dependent methyltransferase | 0.31 | AMB_RS01140 | | LysR family transcriptional regulator | low | > 64 |
Not shown: 11 genomes with orthologs for CSW01_05900 only; 25 genomes with orthologs for CSW01_19025 only