| Organism | Ratio1 | Gene1 | Name1 | Description1 | Ratio2 | Gene2 | Name2 | Description2 | Cofit | Rank |
|---|
| Vibrio cholerae E7946 ATCC 55056 | 1.0 | CSW01_13560 | | methylenetetrahydrofolate reductase | 1.0 | CSW01_13690 | | two-component system sensor histidine kinase EnvZ | 0.70 | 5 |
| Dickeya dianthicola 67-19 | 0.80 | HGI48_RS20415 | | methylenetetrahydrofolate reductase | 0.50 | HGI48_RS19745 | | two-component system sensor histidine kinase EnvZ | low | > 71 |
| Dickeya dianthicola ME23 | 0.79 | DZA65_RS21460 | | methylenetetrahydrofolate reductase | 0.50 | DZA65_RS20835 | | two-component system sensor histidine kinase EnvZ | low | > 75 |
| Dickeya dadantii 3937 | 0.79 | DDA3937_RS00960 | | methylenetetrahydrofolate reductase | 0.50 | DDA3937_RS19615 | | two-component system sensor histidine kinase EnvZ | low | > 74 |
| Enterobacter sp. TBS_079 | 0.79 | MPMX20_04529 | | 5,10-methylenetetrahydrofolate reductase | 0.49 | MPMX20_04291 | | Osmolarity sensor protein EnvZ | low | > 85 |
| Escherichia coli BW25113 | 0.79 | b3941 | metF | 5,10-methylenetetrahydrofolate reductase (NCBI) | 0.49 | b3404 | envZ | osmolarity sensor protein (NCBI) | low | > 76 |
| Escherichia coli BL21 | 0.79 | ECD_03827 | | 5,10-methylenetetrahydrofolate reductase | 0.48 | ECD_03256 | | sensory histidine kinase in two-component regulatory system with OmpR | low | > 61 |
| Escherichia coli ECRC62 | 0.79 | BNILDI_05725 | metF | methylenetetrahydrofolate reductase | 0.49 | BNILDI_02690 | envZ | two-component system sensor histidine kinase EnvZ | low | > 75 |
| Escherichia coli HS(pFamp)R (ATCC 700891) | 0.79 | OHPLBJKB_04109 | | 5,10-methylenetetrahydrofolate reductase | 0.49 | OHPLBJKB_00299 | | Osmolarity sensor protein EnvZ | low | > 74 |
| Escherichia coli ECRC100 | 0.79 | OKFHMN_13665 | metF | methylenetetrahydrofolate reductase | 0.48 | OKFHMN_17040 | envZ | two-component system sensor histidine kinase EnvZ | low | > 79 |
| Escherichia coli ECRC101 | 0.79 | MCAODC_04165 | metF | methylenetetrahydrofolate reductase | 0.48 | MCAODC_07570 | envZ | two-component system sensor histidine kinase EnvZ | low | > 87 |
| Escherichia coli ECRC98 | 0.79 | JDDGAC_17290 | metF | methylenetetrahydrofolate reductase | 0.48 | JDDGAC_20670 | envZ | two-component system sensor histidine kinase EnvZ | low | > 87 |
| Escherichia coli ECRC102 | 0.79 | NIAGMN_11420 | metF | methylenetetrahydrofolate reductase | 0.48 | NIAGMN_14810 | envZ | two-component system sensor histidine kinase EnvZ | low | > 80 |
| Escherichia coli ECRC99 | 0.79 | KEDOAH_14495 | metF | methylenetetrahydrofolate reductase | 0.48 | KEDOAH_11100 | envZ | two-component system sensor histidine kinase EnvZ | — | — |
| Escherichia coli ECOR27 | 0.79 | NOLOHH_05810 | metF | methylenetetrahydrofolate reductase | 0.49 | NOLOHH_08830 | envZ | two-component system sensor histidine kinase EnvZ | low | > 76 |
| Enterobacter asburiae PDN3 | 0.79 | EX28DRAFT_4413 | | 5,10-methylenetetrahydrofolate reductase, prokaryotic form | 0.49 | EX28DRAFT_4139 | | Signal transduction histidine kinase | low | > 76 |
| Pantoea agglomerans CFBP13505 P0401 | 0.78 | PagCFBP13505_RS18450 | | methylenetetrahydrofolate reductase | 0.48 | PagCFBP13505_RS18345 | | two-component system sensor histidine kinase EnvZ | low | > 74 |
| Escherichia coli ECOR38 | 0.78 | HEPCGN_12310 | metF | methylenetetrahydrofolate reductase | 0.48 | HEPCGN_15850 | envZ | two-component system sensor histidine kinase EnvZ | low | > 88 |
| Pantoea sp. MT58 | 0.78 | IAI47_00890 | | methylenetetrahydrofolate reductase | 0.48 | IAI47_01825 | | two-component system sensor histidine kinase EnvZ | low | > 76 |
| Rahnella sp. WP5 | 0.78 | EX31_RS14205 | | methylenetetrahydrofolate reductase | 0.47 | EX31_RS04795 | | two-component system sensor histidine kinase EnvZ | low | > 89 |
| Klebsiella michiganensis M5al | 0.78 | BWI76_RS00805 | | 5,10-methylenetetrahydrofolate reductase | 0.49 | BWI76_RS26670 | | two-component sensor histidine kinase | low | > 92 |
| Escherichia fergusonii Becca | 0.78 | EFB2_04672 | | 5,10-methylenetetrahydrofolate reductase | 0.49 | EFB2_00424 | | Osmolarity sensor protein EnvZ | low | > 86 |
| Klebsiella pneumoniae MKP103 | 0.78 | KDGMDA_09325 | | methylenetetrahydrofolate reductase | 0.49 | KDGMDA_06975 | | two-component system sensor histidine kinase EnvZ | low | > 95 |
| Escherichia coli Nissle 1917 | 0.78 | ECOLIN_RS22760 | | methylenetetrahydrofolate reductase | 0.49 | ECOLIN_RS19450 | | two-component system sensor histidine kinase EnvZ | low | > 55 |
| Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 | 0.77 | GFF2329 | | 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) | 0.49 | GFF614 | | Osmolarity sensory histidine kinase EnvZ | low | > 78 |
| Erwinia amylovora T8 | 0.77 | OLJFJH_06105 | | methylenetetrahydrofolate reductase | 0.49 | OLJFJH_04155 | | two-component system sensor histidine kinase EnvZ | low | > 58 |
| Pectobacterium carotovorum WPP14 | 0.76 | HER17_RS00950 | | methylenetetrahydrofolate reductase | 0.48 | HER17_RS01705 | | two-component system sensor histidine kinase EnvZ | low | > 75 |
| Serratia liquefaciens MT49 | 0.76 | IAI46_24530 | | methylenetetrahydrofolate reductase | 0.48 | IAI46_23785 | | two-component system sensor histidine kinase EnvZ | low | > 87 |
| Shewanella amazonensis SB2B | 0.76 | Sama_3169 | metF | 5,10-methylenetetrahydrofolate reductase (RefSeq) | 0.39 | Sama_3511 | envZ | osmolarity sensor protein (RefSeq) | low | > 62 |
| Erwinia tracheiphila SCR3 | 0.75 | LU632_RS19630 | metF | methylenetetrahydrofolate reductase | 0.45 | LU632_RS22935 | envZ | two-component system sensor histidine kinase EnvZ | low | > 73 |
| Erwinia tracheiphila HP pepo 2.2 | 0.75 | IJEDHG_13030 | metF | methylenetetrahydrofolate reductase | 0.45 | IJEDHG_11960 | envZ | two-component system sensor histidine kinase EnvZ | low | > 61 |
| Shewanella loihica PV-4 | 0.74 | Shew_0522 | metF | 5,10-methylenetetrahydrofolate reductase (RefSeq) | 0.39 | Shew_3638 | envZ | osmolarity sensor protein (RefSeq) | low | > 60 |
| Shewanella sp. ANA-3 | 0.73 | Shewana3_3612 | metF | 5,10-methylenetetrahydrofolate reductase (RefSeq) | 0.39 | Shewana3_4018 | envZ | osmolarity sensor protein (RefSeq) | low | > 73 |
| Shewanella oneidensis MR-1 | 0.73 | SO4054 | metF | 5,10-methylenetetrahydrofolate reductase (NCBI ptt file) | 0.39 | SO4634 | envZ | osmolarity sensor protein EnvZ (NCBI ptt file) | low | > 76 |
| Alteromonas macleodii MIT1002 | 0.66 | MIT1002_03670 | | 5,10-methylenetetrahydrofolate reductase | 0.34 | MIT1002_03969 | | Osmolarity sensor protein EnvZ | low | > 70 |
| Kangiella aquimarina DSM 16071 | 0.57 | B158DRAFT_2461 | | 5,10-methylenetetrahydrofolate reductase (NAD(P)) (EC 1.5.1.20) | 0.28 | B158DRAFT_0685 | | Signal transduction histidine kinase | low | > 40 |
| Paraburkholderia sabiae LMG 24235 | 0.37 | QEN71_RS28715 | | methylenetetrahydrofolate reductase [NAD(P)H] | 0.21 | QEN71_RS22035 | | ATP-binding protein | low | > 153 |
| Paraburkholderia bryophila 376MFSha3.1 | 0.36 | H281DRAFT_05801 | | 5,10-methylenetetrahydrofolate reductase (NAD(P)) | 0.21 | H281DRAFT_00885 | | two-component system, OmpR family, osmolarity sensor histidine kinase EnvZ | low | > 103 |
| Paraburkholderia graminis OAS925 | 0.36 | ABIE53_000061 | | methylenetetrahydrofolate reductase (NADPH) | 0.21 | ABIE53_002100 | | two-component system osmolarity sensor histidine kinase EnvZ | low | > 113 |
| Cupriavidus basilensis FW507-4G11 | 0.35 | RR42_RS01385 | | 5,10-methylenetetrahydrofolate reductase | 0.20 | RR42_RS09525 | | histidine kinase | low | > 128 |
| Burkholderia phytofirmans PsJN | 0.35 | BPHYT_RS18705 | | 5,10-methylenetetrahydrofolate reductase | 0.21 | BPHYT_RS09310 | | sensor histidine kinase | low | > 109 |
| Pseudomonas fluorescens SBW25 | 0.34 | PFLU_RS28165 | | methylenetetrahydrofolate reductase [NAD(P)H] | 0.24 | PFLU_RS01285 | | HAMP domain-containing protein | low | > 109 |
| Pseudomonas fluorescens SBW25-INTG | 0.34 | PFLU_RS28165 | | methylenetetrahydrofolate reductase [NAD(P)H] | 0.24 | PFLU_RS01285 | | HAMP domain-containing protein | low | > 109 |
| Castellaniella sp019104865 MT123 | 0.34 | ABCV34_RS13550 | | methylenetetrahydrofolate reductase [NAD(P)H] | 0.21 | ABCV34_RS08590 | | ATP-binding protein | low | > 48 |
| Acinetobacter baumannii LAC-4 | 0.32 | RR41_RS05725 | | methylenetetrahydrofolate reductase [NAD(P)H] | 0.22 | RR41_RS01385 | | HAMP domain-containing protein | — | — |
| Acinetobacter radioresistens SK82 | 0.32 | MPMX26_01002 | | 5,10-methylenetetrahydrofolate reductase | 0.22 | MPMX26_02839 | | Osmolarity sensor protein EnvZ | low | > 36 |
| Variovorax sp. OAS795 | 0.31 | ABID97_RS25015 | | methylenetetrahydrofolate reductase [NAD(P)H] | 0.18 | ABID97_RS17270 | | ATP-binding protein | low | > 91 |
| Variovorax sp. SCN45 | 0.31 | GFF2055 | | 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) | 0.19 | GFF409 | | Osmolarity sensory histidine kinase EnvZ | low | > 127 |
Not shown: 71 genomes with orthologs for CSW01_13560 only; 0 genomes with orthologs for CSW01_13690 only