| Organism | Ratio1 | Gene1 | Name1 | Description1 | Ratio2 | Gene2 | Name2 | Description2 | Cofit | Rank |
| Vibrio cholerae E7946 ATCC 55056 | 1.0 | CSW01_15345 | | XRE family transcriptional regulator | 1.0 | CSW01_01280 | | GDP-mannose 4,6-dehydratase | 0.76 | 15 |
| Dinoroseobacter shibae DFL-12 | 0.59 | Dshi_1555 | | transcriptional regulator, XRE family (RefSeq) | 0.63 | Dshi_4139 | | GDP-mannose 4,6-dehydratase (RefSeq) | low | > 64 |
| Phaeobacter inhibens DSM 17395 | 0.55 | PGA1_c14960 | | putative transcriptional regulator | 0.81 | PGA1_65p00310 | | GDP-mannose 4,6-dehydratase Gmd | low | > 62 |
| Burkholderia phytofirmans PsJN | 0.45 | BPHYT_RS33425 | | transcriptional regulator | 0.69 | BPHYT_RS04000 | | GDP-mannose 4,6-dehydratase | low | > 109 |
| Paraburkholderia sabiae LMG 24235 | 0.45 | QEN71_RS14815 | | XRE family transcriptional regulator | 0.70 | QEN71_RS26360 | | GDP-mannose 4,6-dehydratase | low | > 153 |
| Paraburkholderia graminis OAS925 | 0.45 | ABIE53_004924 | | transcriptional regulator with XRE-family HTH domain | 0.68 | ABIE53_000940 | | GDPmannose 4,6-dehydratase | low | > 113 |
| Paraburkholderia bryophila 376MFSha3.1 | 0.44 | H281DRAFT_03868 | | transcriptional regulator, XRE family with cupin sensor | 0.69 | H281DRAFT_04776 | | GDPmannose 4,6-dehydratase | low | > 103 |
| Azospirillum brasilense Sp245 | 0.39 | AZOBR_RS27045 | | XRE family transcriptional regulator | 0.44 | AZOBR_RS33465 | | GDP-mannose 4 6-dehydratase | low | > 97 |
| Azospirillum sp. SherDot2 | 0.38 | MPMX19_05211 | | hypothetical protein | 0.63 | MPMX19_06644 | | GDP-mannose 4,6-dehydratase | 0.35 | 17 |
| Castellaniella sp019104865 MT123 | 0.38 | ABCV34_RS09100 | | XRE family transcriptional regulator | 0.71 | ABCV34_RS12935 | | GDP-mannose 4,6-dehydratase | — | — |
| Ralstonia solanacearum PSI07 | 0.29 | RPSI07_RS07485 | | XRE family transcriptional regulator | 0.47 | RPSI07_RS19840 | | GDP-mannose 4,6-dehydratase | low | > 81 |
| Pseudomonas putida KT2440 | 0.22 | PP_2245 | | Transcriptional regulator, Cro/CI family | 0.46 | PP_1799 | | GDP-mannose 4,6-dehydratase | low | > 96 |
| Pseudomonas sp. SVBP6 | 0.21 | COO64_RS09605 | | helix-turn-helix domain-containing protein | 0.45 | COO64_RS06615 | gmd | GDP-mannose 4,6-dehydratase | low | > 93 |
| Pseudomonas fluorescens FW300-N2C3 | 0.18 | AO356_06745 | | DNA-binding protein | 0.40 | AO356_11835 | | GDP-mannose 4,6-dehydratase | low | > 104 |
| Pseudomonas fluorescens FW300-N2E2 | 0.18 | Pf6N2E2_3201 | | Transcriptional regulator, MerR family | 0.40 | Pf6N2E2_4242 | | GDP-mannose 4,6-dehydratase (EC 4.2.1.47) | low | > 103 |
| Pseudomonas lactucae CFBP13502 | 0.17 | GEMAOFIL_03889 | | HTH-type transcriptional regulator SutR | 0.46 | GEMAOFIL_04278 | | GDP-mannose 4,6-dehydratase | low | > 96 |
| Bacteroides thetaiotaomicron VPI-5482 | 0.17 | BT2783 | | transcriptional regulator (NCBI ptt file) | 0.60 | BT1224 | | GDP-mannose 4,6-dehydratase (NCBI ptt file) | — | — |
| Bacteroides ovatus ATCC 8483 | 0.16 | BACOVA_01081 | | hypothetical protein | 0.60 | BACOVA_00511 | | GDP-mannose 4,6-dehydratase | low | > 96 |
| Bacteroides stercoris CC31F | 0.16 | HMPREF1181_RS01200 | | helix-turn-helix transcriptional regulator | 0.60 | HMPREF1181_RS12530 | | GDP-mannose 4,6-dehydratase | low | > 56 |
| Pseudomonas fluorescens SBW25 | 0.15 | PFLU_RS06955 | | helix-turn-helix domain-containing protein | 0.77 | PFLU_RS17890 | | GDP-mannose 4,6-dehydratase | low | > 109 |
| Pseudomonas fluorescens SBW25-INTG | 0.15 | PFLU_RS06955 | | helix-turn-helix domain-containing protein | 0.77 | PFLU_RS17890 | | GDP-mannose 4,6-dehydratase | low | > 109 |
| Enterobacter asburiae PDN3 | 0.15 | EX28DRAFT_1500 | | Predicted transcriptional regulators | 0.83 | EX28DRAFT_0502 | | GDP-mannose 4,6-dehydratase | low | > 76 |
| Pseudomonas fluorescens GW456-L13 | 0.15 | PfGW456L13_4551 | | Transcriptional regulator, MerR family | 0.40 | PfGW456L13_2338 | | GDP-mannose 4,6-dehydratase (EC 4.2.1.47) | low | > 87 |
| Pseudomonas aeruginosa PA14 | 0.15 | IKLFDK_24455 | | DNA-binding protein | 0.39 | IKLFDK_26150 | | GDP-mannose 4 6-dehydratase | low | > 98 |
| Pseudomonas aeruginosa MRSN321 | 0.15 | DY961_RS27395 | | XRE family transcriptional regulator | 0.39 | DY961_RS25555 | gmd;go_function=GDP-mannose | GDP-mannose 4 6-dehydratase | low | > 100 |
| Pseudomonas aeruginosa PUPa3 | 0.15 | DQ20_RS31945 | | XRE family transcriptional regulator | 0.39 | DQ20_RS58005 | gmd;go_function=GDP-mannose | GDP-mannose 4 6-dehydratase | low | > 101 |
| Parabacteroides merdae CL09T00C40 | 0.15 | HMPREF1078_RS17570 | | XRE family transcriptional regulator | 0.63 | HMPREF1078_RS00185 | | GDP-mannose 4,6-dehydratase | low | > 61 |
| Pseudomonas segetis P6 | 0.14 | MPMX49_00005 | | HTH-type transcriptional regulator PuuR | 0.43 | MPMX49_00388 | | GDP-mannose 4,6-dehydratase | low | > 75 |
| Escherichia coli ECRC99 | 0.14 | KEDOAH_26340 | puuR | HTH-type transcriptional regulator PuuR | 0.83 | KEDOAH_03710 | | GDP-mannose 4,6-dehydratase | — | — |
| Escherichia coli HS(pFamp)R (ATCC 700891) | 0.14 | OHPLBJKB_02383 | | HTH-type transcriptional regulator PuuR | 0.10 | OHPLBJKB_04266 | | dTDP-glucose 4,6-dehydratase 2 | low | > 74 |
| Escherichia coli ECRC100 | 0.14 | OKFHMN_02435 | puuR | HTH-type transcriptional regulator PuuR | 0.83 | OKFHMN_24440 | | GDP-mannose 4,6-dehydratase | — | — |
| Escherichia coli ECRC62 | 0.14 | BNILDI_18270 | puuR | HTH-type transcriptional regulator PuuR | 0.83 | BNILDI_14585 | | GDP-mannose 4,6-dehydratase | low | > 75 |
| Escherichia coli ECRC102 | 0.14 | NIAGMN_26605 | puuR | HTH-type transcriptional regulator PuuR | 0.83 | NIAGMN_22385 | | GDP-mannose 4,6-dehydratase | low | > 80 |
| Escherichia coli ECOR38 | 0.14 | HEPCGN_25765 | puuR | HTH-type transcriptional regulator PuuR | 0.83 | HEPCGN_03045 | | GDP-mannose 4,6-dehydratase | low | > 88 |
| Escherichia coli ECOR27 | 0.14 | NOLOHH_20120 | puuR | HTH-type transcriptional regulator PuuR | 0.83 | NOLOHH_15675 | | GDP-mannose 4,6-dehydratase | low | > 76 |
| Escherichia coli BL21 | 0.14 | ECD_01276 | | repressor for the divergent puu operons, putrescine inducible | 0.83 | ECD_01959 | | GDP-D-mannose dehydratase, NAD(P)-binding | low | > 61 |
| Escherichia coli ECRC98 | 0.14 | JDDGAC_04980 | puuR | HTH-type transcriptional regulator PuuR | 0.83 | JDDGAC_28550 | | GDP-mannose 4,6-dehydratase | — | — |
| Escherichia coli BW25113 | 0.14 | b1299 | puuR | DNA-binding transcriptional repressor (NCBI) | 0.83 | b2053 | gmd | GDP-D-mannose dehydratase, NAD(P)-binding (NCBI) | low | > 76 |
| Escherichia coli ECRC101 | 0.14 | MCAODC_15835 | puuR | HTH-type transcriptional regulator PuuR | 0.83 | MCAODC_20500 | | GDP-mannose 4,6-dehydratase | — | — |
| Desulfovibrio vulgaris Hildenborough JW710 | 0.13 | DVU2251 | | DNA-binding protein (TIGR) | 0.69 | DVU0448 | gmd | GDP-mannose 4,6-dehydratase (TIGR) | low | > 55 |
| Echinicola vietnamensis KMM 6221, DSM 17526 | 0.13 | Echvi_4557 | | Predicted transcriptional regulators | 0.66 | Echvi_4398 | | GDP-mannose 4,6-dehydratase | low | > 79 |
| Phocaeicola vulgatus CL09T03C04 | 0.13 | HMPREF1058_RS17685 | | helix-turn-helix transcriptional regulator | 0.61 | HMPREF1058_RS06615 | | GDP-mannose 4,6-dehydratase | low | > 67 |
| Phocaeicola dorei CL03T12C01 | 0.13 | ABI39_RS13885 | | helix-turn-helix transcriptional regulator | 0.61 | ABI39_RS20410 | | GDP-mannose 4,6-dehydratase | low | > 72 |
| Desulfovibrio vulgaris Miyazaki F | 0.13 | DvMF_2356 | | transcriptional regulator, XRE family (RefSeq) | 0.67 | DvMF_2694 | | GDP-mannose 4,6-dehydratase (RefSeq) | low | > 51 |
| Bosea sp. OAE506 | 0.12 | ABIE41_RS05345 | | cupin domain-containing protein | 0.44 | ABIE41_RS02910 | | GDP-mannose 4,6-dehydratase | low | > 77 |
Not shown: 16 genomes with orthologs for CSW01_15345 only; 45 genomes with orthologs for CSW01_01280 only