Conservation of cofitness between BWI76_RS20390 and BWI76_RS25700 in Klebsiella michiganensis M5al

41 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Klebsiella michiganensis M5al 1.0 BWI76_RS20390 erythronate-4-phosphate dehydrogenase 1.0 BWI76_RS25700 heavy metal-responsive transcriptional regulator 0.53 8
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.86 GFF1936 Erythronate-4-phosphate dehydrogenase (EC 1.1.1.290) 0.90 GFF2387 transcriptional regulator, MerR family low > 78
Enterobacter asburiae PDN3 0.84 EX28DRAFT_0284 Phosphoglycerate dehydrogenase and related dehydrogenases 0.89 EX28DRAFT_0035 Zn(II)-responsive transcriptional regulator low > 76
Enterobacter sp. TBS_079 0.83 MPMX20_03255 Erythronate-4-phosphate dehydrogenase 0.88 MPMX20_04200 HTH-type transcriptional regulator ZntR low > 85
Escherichia coli BL21 0.83 ECD_02245 erythronate-4-phosphate dehydrogenase 0.87 ECD_03143 zntA gene transcriptional activator low > 61
Escherichia fergusonii Becca 0.83 EFB2_01538 Erythronate-4-phosphate dehydrogenase 0.87 EFB2_00531 HTH-type transcriptional regulator ZntR low > 86
Escherichia coli Nissle 1917 0.83 ECOLIN_RS13445 4-phosphoerythronate dehydrogenase PdxB 0.87 ECOLIN_RS18895 Zn(2+)-responsive transcriptional regulator — —
Escherichia coli HS(pFamp)R (ATCC 700891) 0.83 OHPLBJKB_01385 Erythronate-4-phosphate dehydrogenase 0.87 OHPLBJKB_00411 HTH-type transcriptional regulator ZntR low > 73
Escherichia coli BW25113 0.83 b2320 pdxB erythronate-4-phosphate dehydrogenase (NCBI) 0.87 b3292 zntR zinc-responsive transcriptional regulator (NCBI) low > 76
Escherichia coli ECRC62 0.82 BNILDI_13215 pdxB 4-phosphoerythronate dehydrogenase PdxB 0.87 BNILDI_02220 zntR Zn(2+)-responsive transcriptional regulator low > 75
Escherichia coli ECOR27 0.82 NOLOHH_14295 pdxB 4-phosphoerythronate dehydrogenase PdxB 0.87 NOLOHH_09300 zntR Zn(2+)-responsive transcriptional regulator low > 75
Escherichia coli ECRC102 0.82 NIAGMN_20435 pdxB 4-phosphoerythronate dehydrogenase PdxB 0.87 NIAGMN_15270 zntR Zn(2+)-responsive transcriptional regulator — —
Escherichia coli ECRC98 0.82 JDDGAC_26620 pdxB 4-phosphoerythronate dehydrogenase PdxB 0.87 JDDGAC_21130 zntR Zn(2+)-responsive transcriptional regulator low > 86
Escherichia coli ECRC101 0.82 MCAODC_13700 pdxB 4-phosphoerythronate dehydrogenase PdxB 0.87 MCAODC_08030 zntR Zn(2+)-responsive transcriptional regulator low > 87
Escherichia coli ECRC100 0.82 OKFHMN_22660 pdxB 4-phosphoerythronate dehydrogenase PdxB 0.87 OKFHMN_17500 zntR Zn(2+)-responsive transcriptional regulator low > 80
Escherichia coli ECRC99 0.82 KEDOAH_05535 pdxB 4-phosphoerythronate dehydrogenase PdxB 0.87 KEDOAH_10640 zntR Zn(2+)-responsive transcriptional regulator — —
Escherichia coli ECOR38 0.81 HEPCGN_21865 pdxB 4-phosphoerythronate dehydrogenase PdxB 0.87 HEPCGN_16330 zntR Zn(2+)-responsive transcriptional regulator low > 87
Pantoea sp. MT58 0.73 IAI47_06235 4-phosphoerythronate dehydrogenase PdxB 0.75 IAI47_02260 Zn(2+)-responsive transcriptional regulator low > 76
Erwinia tracheiphila SCR3 0.73 LU632_RS07815 DUF3410 domain-containing protein 0.74 LU632_RS22515 zntR Zn(2+)-responsive transcriptional regulator — —
Rahnella sp. WP5 0.72 EX31_RS19610 4-phosphoerythronate dehydrogenase PdxB 0.66 EX31_RS16005 Zn(2+)-responsive transcriptional regulator low > 89
Serratia liquefaciens MT49 0.72 IAI46_17850 4-phosphoerythronate dehydrogenase PdxB 0.82 IAI46_23295 Zn(2+)-responsive transcriptional regulator low > 86
Vibrio cholerae E7946 ATCC 55056 0.48 CSW01_10525 DUF3410 domain-containing protein 0.44 CSW01_01430 Zn(2+)-responsive transcriptional regulator — —
Shewanella sp. ANA-3 0.43 Shewana3_1476 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region (RefSeq) 0.50 Shewana3_0442 zntR zinc-responsive transcriptional regulator (RefSeq) — —
Shewanella oneidensis MR-1 0.43 SO3071 pdxB erythronate-4-phosphate dehydrogenase (NCBI ptt file) 0.49 SO0443 transcriptional regulator, MerR family (NCBI ptt file) — —
Pseudomonas syringae pv. syringae B728a ΔmexB 0.43 Psyr_1828 4-phosphoerythronate dehydrogenase 0.31 Psyr_4838 transcriptional regulator, MerR family — —
Pseudomonas syringae pv. syringae B728a 0.43 Psyr_1828 4-phosphoerythronate dehydrogenase 0.31 Psyr_4838 transcriptional regulator, MerR family — —
Pseudomonas fluorescens GW456-L13 0.42 PfGW456L13_4048 Erythronate-4-phosphate dehydrogenase (EC 1.1.1.290) 0.30 PfGW456L13_958 Cd(II)/Pb(II)-responsive transcriptional regulator — —
Pseudomonas fluorescens FW300-N2E3 0.42 AO353_00545 erythronate-4-phosphate dehydrogenase 0.30 AO353_08425 Cd(II)/Pb(II)-responsive transcriptional regulator — —
Shewanella loihica PV-4 0.41 Shew_2309 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding (RefSeq) 0.51 Shew_3411 zntR zinc-responsive transcriptional regulator (RefSeq) — —
Pseudomonas fluorescens FW300-N1B4 0.41 Pf1N1B4_3893 Erythronate-4-phosphate dehydrogenase (EC 1.1.1.290) 0.29 Pf1N1B4_2290 Cd(II)/Pb(II)-responsive transcriptional regulator — —
Pseudomonas simiae WCS417 0.41 PS417_07535 erythronate-4-phosphate dehydrogenase 0.30 PS417_26960 Cd(II)/Pb(II)-responsive transcriptional regulator — —
Pseudomonas fluorescens FW300-N2C3 0.40 AO356_02365 erythronate-4-phosphate dehydrogenase 0.29 AO356_10375 Cd(II)/Pb(II)-responsive transcriptional regulator — —
Pseudomonas fluorescens FW300-N2E2 0.40 Pf6N2E2_2297 Erythronate-4-phosphate dehydrogenase (EC 1.1.1.290) 0.29 Pf6N2E2_3947 Cd(II)/Pb(II)-responsive transcriptional regulator — —
Pseudomonas fluorescens SBW25-INTG 0.40 PFLU_RS07615 4-phosphoerythronate dehydrogenase PdxB 0.31 PFLU_RS28620 Cd(II)/Pb(II)-responsive transcriptional regulator — —
Pseudomonas fluorescens SBW25 0.40 PFLU_RS07615 4-phosphoerythronate dehydrogenase PdxB 0.31 PFLU_RS28620 Cd(II)/Pb(II)-responsive transcriptional regulator — —
Kangiella aquimarina DSM 16071 0.40 B158DRAFT_1308 4-phosphoerythronate dehydrogenase (EC 1.1.1.290) 0.30 B158DRAFT_1624 Hg(II)-responsive transcriptional regulator — —
Pseudomonas sp. RS175 0.39 PFR28_01103 Erythronate-4-phosphate dehydrogenase 0.29 PFR28_04825 Mercuric resistance operon regulatory protein — —
Marinobacter adhaerens HP15 0.38 HP15_2098 erythronate-4-phosphate dehydrogenase 0.33 HP15_89 transcriptional regulator, MerR family protein — —
Pseudomonas putida KT2440 0.38 PP_2117 Erythronate-4-phosphate dehydrogenase 0.29 PP_5140 Transcriptional regulator, MerR family — —
Pseudomonas sp. S08-1 0.37 OH686_02070 Erythronate-4-phosphate dehydrogenase 0.26 OH686_16085 Transcriptional regulator, MerR family — —
Pseudomonas stutzeri RCH2 0.37 Psest_2548 Phosphoglycerate dehydrogenase and related dehydrogenases 0.33 Psest_2758 Predicted transcriptional regulators — —
Alteromonas macleodii MIT1002 0.32 MIT1002_02532 Erythronate-4-phosphate dehydrogenase 0.30 MIT1002_02061 Mercuric resistance operon regulatory protein — —

Not shown: 12 genomes with orthologs for BWI76_RS20390 only; 15 genomes with orthologs for BWI76_RS25700 only