Conservation of cofitness between BWI76_RS10700 and BWI76_RS25700 in Klebsiella michiganensis M5al

40 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Klebsiella michiganensis M5al 1.0 BWI76_RS10700 XRE family transcriptional regulator 1.0 BWI76_RS25700 heavy metal-responsive transcriptional regulator 0.21 17
Enterobacter asburiae PDN3 0.98 EX28DRAFT_1500 Predicted transcriptional regulators 0.89 EX28DRAFT_0035 Zn(II)-responsive transcriptional regulator low > 76
Escherichia coli ECOR27 0.97 NOLOHH_20120 puuR HTH-type transcriptional regulator PuuR 0.87 NOLOHH_09300 zntR Zn(2+)-responsive transcriptional regulator low > 75
Escherichia coli BL21 0.97 ECD_01276 repressor for the divergent puu operons, putrescine inducible 0.87 ECD_03143 zntA gene transcriptional activator low > 61
Escherichia coli ECRC62 0.97 BNILDI_18270 puuR HTH-type transcriptional regulator PuuR 0.87 BNILDI_02220 zntR Zn(2+)-responsive transcriptional regulator low > 75
Escherichia coli BW25113 0.97 b1299 puuR DNA-binding transcriptional repressor (NCBI) 0.87 b3292 zntR zinc-responsive transcriptional regulator (NCBI) low > 76
Escherichia coli HS(pFamp)R (ATCC 700891) 0.97 OHPLBJKB_02383 HTH-type transcriptional regulator PuuR 0.87 OHPLBJKB_00411 HTH-type transcriptional regulator ZntR low > 73
Escherichia coli ECOR38 0.97 HEPCGN_25765 puuR HTH-type transcriptional regulator PuuR 0.87 HEPCGN_16330 zntR Zn(2+)-responsive transcriptional regulator low > 87
Escherichia coli ECRC99 0.97 KEDOAH_26340 puuR HTH-type transcriptional regulator PuuR 0.87 KEDOAH_10640 zntR Zn(2+)-responsive transcriptional regulator
Escherichia coli ECRC100 0.97 OKFHMN_02435 puuR HTH-type transcriptional regulator PuuR 0.87 OKFHMN_17500 zntR Zn(2+)-responsive transcriptional regulator low > 80
Escherichia coli ECRC102 0.97 NIAGMN_26605 puuR HTH-type transcriptional regulator PuuR 0.87 NIAGMN_15270 zntR Zn(2+)-responsive transcriptional regulator
Escherichia coli ECRC98 0.97 JDDGAC_04980 puuR HTH-type transcriptional regulator PuuR 0.87 JDDGAC_21130 zntR Zn(2+)-responsive transcriptional regulator low > 86
Escherichia coli ECRC101 0.97 MCAODC_15835 puuR HTH-type transcriptional regulator PuuR 0.87 MCAODC_08030 zntR Zn(2+)-responsive transcriptional regulator low > 87
Serratia liquefaciens MT49 0.89 IAI46_10550 HTH-type transcriptional regulator PuuR 0.82 IAI46_23295 Zn(2+)-responsive transcriptional regulator low > 86
Rahnella sp. WP5 0.80 EX31_RS17905 HTH-type transcriptional regulator PuuR 0.66 EX31_RS16005 Zn(2+)-responsive transcriptional regulator low > 89
Pantoea sp. MT58 0.74 IAI47_07115 HTH-type transcriptional regulator PuuR 0.75 IAI47_02260 Zn(2+)-responsive transcriptional regulator low > 76
Pseudomonas stutzeri RCH2 0.41 Psest_3791 Predicted transcriptional regulators 0.33 Psest_2758 Predicted transcriptional regulators low > 67
Shewanella sp. ANA-3 0.39 Shewana3_3100 XRE family transcriptional regulator (RefSeq) 0.50 Shewana3_0442 zntR zinc-responsive transcriptional regulator (RefSeq) low > 73
Shewanella oneidensis MR-1 0.39 SO1265 transcriptional regulator, putative (NCBI ptt file) 0.49 SO0443 transcriptional regulator, MerR family (NCBI ptt file) low > 76
Shewanella loihica PV-4 0.39 Shew_0970 XRE family transcriptional regulator (RefSeq) 0.51 Shew_3411 zntR zinc-responsive transcriptional regulator (RefSeq) low > 60
Pseudomonas fluorescens FW300-N2E3 0.38 AO353_09140 XRE family transcriptional regulator 0.30 AO353_08425 Cd(II)/Pb(II)-responsive transcriptional regulator low > 101
Pseudomonas sp. RS175 0.38 PFR28_04396 HTH-type transcriptional regulator PuuR 0.29 PFR28_04825 Mercuric resistance operon regulatory protein low > 88
Pseudomonas sp. S08-1 0.38 OH686_13700 Putrescine utilization regulator 0.26 OH686_16085 Transcriptional regulator, MerR family low > 80
Pseudomonas fluorescens GW456-L13 0.37 PfGW456L13_815 Putrescine utilization regulator 0.30 PfGW456L13_958 Cd(II)/Pb(II)-responsive transcriptional regulator low > 87
Pseudomonas putida KT2440 0.37 PP_5268 DNA-binding transcriptional repressor PuuR-putrescine 0.29 PP_5140 Transcriptional regulator, MerR family low > 96
Pseudomonas fluorescens FW300-N2E2 0.37 Pf6N2E2_4394 Putrescine utilization regulator 0.29 Pf6N2E2_3947 Cd(II)/Pb(II)-responsive transcriptional regulator low > 103
Pseudomonas fluorescens FW300-N2C3 0.37 AO356_12635 XRE family transcriptional regulator 0.29 AO356_10375 Cd(II)/Pb(II)-responsive transcriptional regulator low > 104
Pseudomonas syringae pv. syringae B728a ΔmexB 0.37 Psyr_0238 Helix-turn-helix motif protein 0.31 Psyr_4838 transcriptional regulator, MerR family low > 86
Pseudomonas syringae pv. syringae B728a 0.37 Psyr_0238 Helix-turn-helix motif protein 0.31 Psyr_4838 transcriptional regulator, MerR family low > 86
Pseudomonas fluorescens FW300-N1B4 0.36 Pf1N1B4_2147 Putrescine utilization regulator 0.29 Pf1N1B4_2290 Cd(II)/Pb(II)-responsive transcriptional regulator low > 87
Pseudomonas fluorescens SBW25 0.36 PFLU_RS29365 cupin domain-containing protein 0.31 PFLU_RS28620 Cd(II)/Pb(II)-responsive transcriptional regulator low > 109
Pseudomonas fluorescens SBW25-INTG 0.36 PFLU_RS29365 cupin domain-containing protein 0.31 PFLU_RS28620 Cd(II)/Pb(II)-responsive transcriptional regulator low > 109
Pseudomonas simiae WCS417 0.36 PS417_27690 XRE family transcriptional regulator 0.30 PS417_26960 Cd(II)/Pb(II)-responsive transcriptional regulator
Azospirillum sp. SherDot2 0.32 MPMX19_04921 HTH-type transcriptional regulator PuuR 0.31 MPMX19_06703 HTH-type transcriptional regulator HmrR low > 112
Bosea sp. OAE506 0.32 ABIE41_RS05345 cupin domain-containing protein 0.29 ABIE41_RS05340 helix-turn-helix domain-containing protein low > 77
Rhodospirillum rubrum S1H 0.30 Rru_A2042 Transcriptional Regulator, XRE family with Cupin sensor domain (NCBI) 0.31 Rru_A1026 Transcriptional Regulator, MerR family (NCBI) low > 58
Agrobacterium fabrum C58 0.28 Atu3328 aldehyde dehydrogenase 0.28 Atu0888 transcriptional regulator, MerR family low > 89
Paraburkholderia bryophila 376MFSha3.1 0.19 H281DRAFT_03130 transcriptional regulator, XRE family with cupin sensor 0.30 H281DRAFT_02296 transcriptional regulator, MerR family low > 103
Paraburkholderia graminis OAS925 0.19 ABIE53_004168 transcriptional regulator with XRE-family HTH domain 0.29 ABIE53_000366 Cd(II)/Pb(II)-responsive transcriptional regulator low > 113
Vibrio cholerae E7946 ATCC 55056 0.16 CSW01_15345 XRE family transcriptional regulator 0.44 CSW01_01430 Zn(2+)-responsive transcriptional regulator low > 62
Variovorax sp. OAS795 0.14 ABID97_RS13245 XRE family transcriptional regulator 0.35 ABID97_RS20720 Cd(II)/Pb(II)-responsive transcriptional regulator low > 91

Not shown: 13 genomes with orthologs for BWI76_RS10700 only; 16 genomes with orthologs for BWI76_RS25700 only