Conservation of cofitness between BWI76_RS16755 and BWI76_RS20410 in Klebsiella michiganensis M5al

33 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Klebsiella michiganensis M5al 1.0 BWI76_RS16755 acetoin reductase 1.0 BWI76_RS20410 bifunctional tRNA (5-methylaminomethyl-2-thiouridine)(34)-methyltransferase MnmD/FAD-dependent 5-carboxymethylaminomethyl-2-thiouridine(34) oxidoreductase MnmC 0.24 3
Enterobacter sp. TBS_079 0.90 MPMX20_01225 Diacetyl reductase [(S)-acetoin forming] 0.74 MPMX20_03259 tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC low > 85
Enterobacter asburiae PDN3 0.89 EX28DRAFT_2401 acetoin reductases 0.75 EX28DRAFT_0280 tRNA U-34 5-methylaminomethyl-2-thiouridine biosynthesis protein MnmC, C-terminal domain low > 76
Pantoea sp. MT58 0.84 IAI47_21750 (S)-acetoin forming diacetyl reductase 0.63 IAI47_06175 bifunctional tRNA (5-methylaminomethyl-2-thiouridine)(34)-methyltransferase MnmD/FAD-dependent 5-carboxymethylaminomethyl-2-thiouridine(34) oxidoreductase MnmC low > 76
Dickeya dadantii 3937 0.83 DDA3937_RS16280 (S)-acetoin forming diacetyl reductase 0.59 DDA3937_RS14515 bifunctional tRNA (5-methylaminomethyl-2-thiouridine)(34)-methyltransferase MnmD/FAD-dependent 5-carboxymethylaminomethyl-2-thiouridine(34) oxidoreductase MnmC low > 74
Rahnella sp. WP5 0.82 EX31_RS01815 (S)-acetoin forming diacetyl reductase 0.59 EX31_RS19660 bifunctional tRNA (5-methylaminomethyl-2-thiouridine)(34)-methyltransferase MnmD/FAD-dependent 5-carboxymethylaminomethyl-2-thiouridine(34) oxidoreductase MnmC low > 89
Dickeya dianthicola 67-19 0.82 HGI48_RS16380 (S)-acetoin forming diacetyl reductase 0.59 HGI48_RS14485 bifunctional tRNA (5-methylaminomethyl-2-thiouridine)(34)-methyltransferase MnmD/FAD-dependent 5-carboxymethylaminomethyl-2-thiouridine(34) oxidoreductase MnmC low > 71
Dickeya dianthicola ME23 0.82 DZA65_RS17475 (S)-acetoin forming diacetyl reductase 0.58 DZA65_RS15420 bifunctional tRNA (5-methylaminomethyl-2-thiouridine)(34)-methyltransferase MnmD/FAD-dependent 5-carboxymethylaminomethyl-2-thiouridine(34) oxidoreductase MnmC low > 75
Pectobacterium carotovorum WPP14 0.81 HER17_RS19925 (S)-acetoin forming diacetyl reductase 0.60 HER17_RS06960 bifunctional tRNA (5-methylaminomethyl-2-thiouridine)(34)-methyltransferase MnmD/FAD-dependent 5-carboxymethylaminomethyl-2-thiouridine(34) oxidoreductase MnmC low > 75
Paraburkholderia sabiae LMG 24235 0.33 QEN71_RS02585 L-iditol 2-dehydrogenase 0.22 QEN71_RS29485 bifunctional tRNA (5-methylaminomethyl-2-thiouridine)(34)-methyltransferase MnmD/FAD-dependent 5-carboxymethylaminomethyl-2-thiouridine(34) oxidoreductase MnmC low > 153
Burkholderia phytofirmans PsJN 0.33 BPHYT_RS16120 sorbitol dehydrogenase, D-fructose forming (EC 1.1.1.14) (from data) 0.23 BPHYT_RS19575 tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC low > 109
Paraburkholderia graminis OAS925 0.33 ABIE53_003397 D-sorbitol dehydrogenase (acceptor) 0.24 ABIE53_000291 tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein low > 113
Paraburkholderia bryophila 376MFSha3.1 0.32 H281DRAFT_04160 D-sorbitol dehydrogenase (acceptor) 0.23 H281DRAFT_02360 tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein low > 103
Ralstonia solanacearum GMI1000 0.32 RS_RS10765 3-oxoacyl-ACP reductase 0.25 RS_RS08635 bifunctional tRNA (5-methylaminomethyl-2-thiouridine)(34)-methyltransferase MnmD/FAD-dependent 5-carboxymethylaminomethyl-2-thiouridine(34) oxidoreductase MnmC low > 80
Pseudomonas fluorescens FW300-N2E2 0.32 Pf6N2E2_1959 D-sorbitol dehydrogenase (EC 1.1.1.14) (from data) 0.31 Pf6N2E2_2541 5-methylaminomethyl-2-thiouridine-forming enzyme mnmC low > 103
Pseudomonas syringae pv. syringae B728a 0.31 Psyr_4813 Short-chain dehydrogenase/reductase SDR 0.30 Psyr_3742 FAD dependent oxidoreductase:Protein of unknown function DUF752 low > 86
Pseudomonas syringae pv. syringae B728a ΔmexB 0.31 Psyr_4813 Short-chain dehydrogenase/reductase SDR 0.30 Psyr_3742 FAD dependent oxidoreductase:Protein of unknown function DUF752 low > 86
Pseudomonas fluorescens FW300-N1B4 0.31 Pf1N1B4_5039 Multiple polyol-specific dehydrogenase (EC 1.1.1.-) 0.31 Pf1N1B4_373 5-methylaminomethyl-2-thiouridine-forming enzyme mnmC low > 87
Pseudomonas fluorescens FW300-N2C3 0.31 AO356_25515 3-ketoacyl-ACP reductase 0.32 AO356_03570 FAD-dependent cmnm(5)s(2)U34 oxidoreductase — —
Pseudomonas sp. S08-1 0.30 OH686_20185 Cyclic-di-GMP-binding biofilm dispersal mediator protein 0.29 OH686_20990 tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase / FAD-dependent cmnm(5)s(2)U34 oxidoreductase low > 80
Pseudomonas fluorescens GW456-L13 0.29 PfGW456L13_437 3-oxoacyl-[acyl-carrier protein] reductase (EC 1.1.1.100) 0.32 PfGW456L13_2155 tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase (EC 2.1.1.61) / FAD-dependent cmnm(5)s(2)U34 oxidoreductase low > 87
Caulobacter crescentus NA1000 0.29 CCNA_01885 short chain dehydrogenase 0.14 CCNA_00785 tRNA methyltransferase/FAD-dependent oxidoreductase MnmC low > 66
Caulobacter crescentus NA1000 Δfur 0.29 CCNA_01885 short chain dehydrogenase 0.14 CCNA_00785 tRNA methyltransferase/FAD-dependent oxidoreductase MnmC low > 67
Herbaspirillum seropedicae SmR1 0.29 HSERO_RS06265 3-hydroxybutyrate dehydrogenase 0.17 HSERO_RS23825 hypothetical protein low > 78
Variovorax sp. SCN45 0.29 GFF1032 Oxidoreductase, short-chain dehydrogenase/reductase family 0.16 GFF1245 tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase (EC 2.1.1.61) / FAD-dependent cmnm(5)s(2)U34 oxidoreductase low > 127
Serratia liquefaciens MT49 0.28 IAI46_19920 SDR family oxidoreductase 0.61 IAI46_18000 bifunctional tRNA (5-methylaminomethyl-2-thiouridine)(34)-methyltransferase MnmD/FAD-dependent 5-carboxymethylaminomethyl-2-thiouridine(34) oxidoreductase MnmC low > 86
Shewanella loihica PV-4 0.28 Shew_2863 short-chain dehydrogenase/reductase SDR (RefSeq) 0.23 Shew_2411 FAD dependent oxidoreductase (RefSeq) low > 60
Pseudomonas putida KT2440 0.28 PP_1852 putative enoyl-[acyl-carrier-protein] reductase (NADPH, B-specific) 0.30 PP_1751 methyltransferase/FAD-dependent oxidoreductase low > 96
Acidovorax sp. GW101-3H11 0.28 Ac3H11_1292 Enoyl-[acyl-carrier-protein] reductase [NADPH] (EC 1.3.1.10) 0.13 Ac3H11_579 tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase (EC 2.1.1.61) / FAD-dependent cmnm(5)s(2)U34 oxidoreductase low > 79
Ralstonia solanacearum IBSBF1503 0.28 RALBFv3_RS18705 3-hydroxybutyrate dehydrogenase 0.25 RALBFv3_RS01360 bifunctional tRNA (5-methylaminomethyl-2-thiouridine)(34)-methyltransferase MnmD/FAD-dependent 5-carboxymethylaminomethyl-2-thiouridine(34) oxidoreductase MnmC low > 76
Pseudomonas sp. RS175 0.28 PFR28_04858 3-oxoacyl-[acyl-carrier-protein] reductase FabG 0.31 PFR28_00884 tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC low > 88
Ralstonia solanacearum UW163 0.28 UW163_RS20425 3-hydroxybutyrate dehydrogenase 0.25 UW163_RS14670 bifunctional tRNA (5-methylaminomethyl-2-thiouridine)(34)-methyltransferase MnmD/FAD-dependent 5-carboxymethylaminomethyl-2-thiouridine(34) oxidoreductase MnmC — —
Variovorax sp. OAS795 0.27 ABID97_RS14375 3-hydroxybutyrate dehydrogenase 0.16 ABID97_RS15455 FAD-dependent 5-carboxymethylaminomethyl-2-thiouridine(34) oxidoreductase MnmC low > 91
Alteromonas macleodii MIT1002 0.26 MIT1002_02275 4-formylbenzenesulfonate dehydrogenase TsaC1/TsaC2 0.29 MIT1002_02542 tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC low > 70

Not shown: 9 genomes with orthologs for BWI76_RS16755 only; 32 genomes with orthologs for BWI76_RS20410 only