Conservation of cofitness between BWI76_RS02510 and BWI76_RS00245 in Klebsiella michiganensis M5al

42 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Klebsiella michiganensis M5al 1.0 BWI76_RS02510 bifunctional ADP-dependent NAD(P)H-hydrate dehydratase/NAD(P)H-hydrate epimerase 1.0 BWI76_RS00245 transcriptional regulator AsnC 0.26 6
Enterobacter asburiae PDN3 0.80 EX28DRAFT_3364 yjeF C-terminal region, hydroxyethylthiazole kinase-related/yjeF N-terminal region 0.96 EX28DRAFT_4019 Transcriptional regulators low > 76
Escherichia coli Nissle 1917 0.79 ECOLIN_RS24205 bifunctional ADP-dependent NAD(P)H-hydrate dehydratase/NAD(P)H-hydrate epimerase 0.97 ECOLIN_RS21525 transcriptional regulator AsnC low > 55
Enterobacter sp. TBS_079 0.79 MPMX20_00448 Bifunctional NAD(P)H-hydrate repair enzyme Nnr 0.96 MPMX20_04624 Regulatory protein AsnC low > 85
Escherichia coli BW25113 0.79 b4167 yjeF predicted carbohydrate kinase (NCBI) 0.97 b3743 asnC DNA-binding transcriptional dual regulator (NCBI) low > 76
Escherichia coli BL21 0.79 ECD_04034 bifunctional NAD(P)H-hydrate repair enzyme; C-terminal domain ADP-dependent (S)-NAD(P)H-hydrate dehydratase and N-terminal domain NAD(P)H-hydrate epimerase 0.97 ECD_03627 transcriptional activator of asnA; autorepressor low > 61
Escherichia coli ECRC102 0.78 NIAGMN_10130 nnr bifunctional ADP-dependent NAD(P)H-hydrate dehydratase/NAD(P)H-hydrate epimerase 0.97 NIAGMN_12530 asnC transcriptional regulator AsnC — —
Escherichia coli ECRC101 0.78 MCAODC_02795 nnr bifunctional ADP-dependent NAD(P)H-hydrate dehydratase/NAD(P)H-hydrate epimerase 0.97 MCAODC_05280 asnC transcriptional regulator AsnC low > 87
Escherichia coli ECRC98 0.78 JDDGAC_15920 nnr bifunctional ADP-dependent NAD(P)H-hydrate dehydratase/NAD(P)H-hydrate epimerase 0.97 JDDGAC_18395 asnC transcriptional regulator AsnC low > 86
Escherichia coli ECRC99 0.78 KEDOAH_15875 nnr bifunctional ADP-dependent NAD(P)H-hydrate dehydratase/NAD(P)H-hydrate epimerase 0.97 KEDOAH_13375 asnC transcriptional regulator AsnC — —
Escherichia coli ECRC100 0.78 OKFHMN_12280 nnr bifunctional ADP-dependent NAD(P)H-hydrate dehydratase/NAD(P)H-hydrate epimerase 0.97 OKFHMN_14775 asnC transcriptional regulator AsnC low > 80
Escherichia fergusonii Becca 0.78 EFB2_04368 Bifunctional NAD(P)H-hydrate repair enzyme Nnr 0.97 EFB2_04890 Regulatory protein AsnC low > 86
Escherichia coli ECRC62 0.78 BNILDI_06945 nnr bifunctional ADP-dependent NAD(P)H-hydrate dehydratase/NAD(P)H-hydrate epimerase 0.97 BNILDI_04615 asnC transcriptional regulator AsnC low > 75
Escherichia coli ECOR27 0.78 NOLOHH_04545 nnr bifunctional ADP-dependent NAD(P)H-hydrate dehydratase/NAD(P)H-hydrate epimerase 0.97 NOLOHH_06910 asnC transcriptional regulator AsnC low > 75
Escherichia coli HS(pFamp)R (ATCC 700891) 0.78 OHPLBJKB_03875 Bifunctional NAD(P)H-hydrate repair enzyme Nnr 0.97 OHPLBJKB_04310 Regulatory protein AsnC low > 73
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.78 GFF820 NAD(P)HX epimerase / NAD(P)HX dehydratase 0.97 GFF1714 Regulatory protein AsnC low > 78
Escherichia coli ECOR38 0.78 HEPCGN_10510 nnr bifunctional ADP-dependent NAD(P)H-hydrate dehydratase/NAD(P)H-hydrate epimerase 0.97 HEPCGN_13490 asnC transcriptional regulator AsnC low > 87
Erwinia tracheiphila SCR3 0.67 LU632_RS02030 nnr bifunctional ADP-dependent NAD(P)H-hydrate dehydratase/NAD(P)H-hydrate epimerase 0.86 LU632_RS24700 asnC transcriptional regulator AsnC low > 74
Rahnella sp. WP5 0.65 EX31_RS08845 bifunctional ADP-dependent NAD(P)H-hydrate dehydratase/NAD(P)H-hydrate epimerase 0.84 EX31_RS06150 transcriptional regulator AsnC low > 89
Dickeya dianthicola 67-19 0.64 HGI48_RS18570 bifunctional ADP-dependent NAD(P)H-hydrate dehydratase/NAD(P)H-hydrate epimerase 0.85 HGI48_RS21370 transcriptional regulator AsnC low > 71
Pantoea sp. MT58 0.64 IAI47_02565 bifunctional ADP-dependent NAD(P)H-hydrate dehydratase/NAD(P)H-hydrate epimerase 0.85 IAI47_00310 transcriptional regulator AsnC low > 76
Dickeya dianthicola ME23 0.63 DZA65_RS19705 bifunctional ADP-dependent NAD(P)H-hydrate dehydratase/NAD(P)H-hydrate epimerase 0.86 DZA65_RS22350 transcriptional regulator AsnC low > 75
Serratia liquefaciens MT49 0.63 IAI46_01600 bifunctional ADP-dependent NAD(P)H-hydrate dehydratase/NAD(P)H-hydrate epimerase 0.88 IAI46_25100 transcriptional regulator AsnC low > 86
Pectobacterium carotovorum WPP14 0.62 HER17_RS02560 bifunctional ADP-dependent NAD(P)H-hydrate dehydratase/NAD(P)H-hydrate epimerase 0.79 HER17_RS21590 transcriptional regulator AsnC low > 75
Dickeya dadantii 3937 0.60 DDA3937_RS18635 bifunctional ADP-dependent NAD(P)H-hydrate dehydratase/NAD(P)H-hydrate epimerase 0.85 DDA3937_RS00010 transcriptional regulator AsnC low > 74
Vibrio cholerae E7946 ATCC 55056 0.39 CSW01_14940 bifunctional ADP-dependent NAD(P)H-hydrate dehydratase/NAD(P)H-hydrate epimerase 0.69 CSW01_00385 transcriptional regulator AsnC low > 62
Shewanella amazonensis SB2B 0.36 Sama_3030 YjeF protein (RefSeq) 0.76 Sama_0605 DNA-binding transcriptional regulator AsnC (RefSeq) low > 62
Shewanella sp. ANA-3 0.36 Shewana3_0592 carbohydrate kinase, YjeF related protein (RefSeq) 0.76 Shewana3_0798 DNA-binding transcriptional regulator AsnC (RefSeq) low > 73
Shewanella oneidensis MR-1 0.36 SO0598 yjeF yjeF protein (NCBI ptt file) 0.76 SO3799 asnC regulatory protein AsnC (NCBI ptt file) low > 76
Shewanella loihica PV-4 0.34 Shew_0561 carbohydrate kinase, YjeF-related protein (RefSeq) 0.76 Shew_0782 DNA-binding transcriptional regulator AsnC (RefSeq) low > 60
Kangiella aquimarina DSM 16071 0.27 B158DRAFT_1947 yjeF C-terminal region, hydroxyethylthiazole kinase-related/yjeF N-terminal region 0.60 B158DRAFT_1998 Transcriptional regulators low > 40
Parabacteroides merdae CL09T00C40 0.21 HMPREF1078_RS15325 bifunctional ADP-dependent NAD(P)H-hydrate dehydratase/NAD(P)H-hydrate epimerase 0.33 HMPREF1078_RS11155 Lrp/AsnC ligand binding domain-containing protein low > 61
Pontibacter actiniarum KMM 6156, DSM 19842 0.20 CA264_16280 bifunctional ADP-dependent NAD(P)H-hydrate dehydratase/NAD(P)H-hydrate epimerase 0.46 CA264_16260 transcriptional regulator AsnC low > 74
Castellaniella sp019104865 MT123 0.20 ABCV34_RS02980 NAD(P)H-hydrate dehydratase 0.20 ABCV34_RS02305 Lrp/AsnC family transcriptional regulator low > 48
Bacteroides thetaiotaomicron VPI-5482 0.20 BT4383 putative sugar kinase (NCBI ptt file) 0.34 BT2978 transcriptional regulator (NCBI ptt file) — —
Bacteroides stercoris CC31F 0.20 HMPREF1181_RS06260 bifunctional ADP-dependent NAD(P)H-hydrate dehydratase/NAD(P)H-hydrate epimerase 0.35 HMPREF1181_RS01345 Lrp/AsnC ligand binding domain-containing protein low > 56
Pedobacter sp. GW460-11-11-14-LB5 0.18 CA265_RS24885 bifunctional ADP-dependent NAD(P)H-hydrate dehydratase/NAD(P)H-hydrate epimerase 0.46 CA265_RS18950 transcriptional regulator low > 88
Phocaeicola vulgatus CL09T03C04 0.18 HMPREF1058_RS00705 bifunctional ADP-dependent NAD(P)H-hydrate dehydratase/NAD(P)H-hydrate epimerase 0.34 HMPREF1058_RS12070 Lrp/AsnC ligand binding domain-containing protein low > 67
Echinicola vietnamensis KMM 6221, DSM 17526 0.18 Echvi_0073 yjeF C-terminal region, hydroxyethylthiazole kinase-related/yjeF N-terminal region 0.43 Echvi_3066 Transcriptional regulators — —
Phocaeicola dorei CL03T12C01 0.18 ABI39_RS08310 bifunctional ADP-dependent NAD(P)H-hydrate dehydratase/NAD(P)H-hydrate epimerase 0.34 ABI39_RS04730 Lrp/AsnC ligand binding domain-containing protein low > 72
Mucilaginibacter yixingensis YX-36 DSM 26809 0.17 ABZR88_RS18865 NAD(P)H-hydrate dehydratase 0.46 ABZR88_RS21700 Lrp/AsnC ligand binding domain-containing protein low > 71
Methanococcus maripaludis S2 0.12 MMP_RS01375 bifunctional ADP-dependent NAD(P)H-hydrate dehydratase/NAD(P)H-hydrate epimerase 0.20 MMP_RS05870 Lrp/AsnC family transcriptional regulator — —
Methanococcus maripaludis JJ 0.12 MMJJ_RS04000 NAD(P)H-hydrate dehydratase 0.20 MMJJ_RS08485 Lrp/AsnC family transcriptional regulator low > 28

Not shown: 52 genomes with orthologs for BWI76_RS02510 only; 0 genomes with orthologs for BWI76_RS00245 only