Conservation of cofitness between ABZR87_RS14930 and ABZR87_RS12585 in Ralstonia sp. UNC404CL21Col

41 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Ralstonia sp. UNC404CL21Col 1.0 ABZR87_RS14930 2-isopropylmalate synthase 1.0 ABZR87_RS12585 3-hydroxyacyl-CoA dehydrogenase NAD-binding domain-containing protein 0.32 8
Ralstonia solanacearum GMI1000 0.99 RS_RS10395 2-isopropylmalate synthase 0.93 RS_RS08885 3-hydroxyacyl-CoA dehydrogenase low > 80
Ralstonia solanacearum IBSBF1503 0.97 RALBFv3_RS03025 2-isopropylmalate synthase 0.93 RALBFv3_RS01130 3-hydroxyacyl-CoA dehydrogenase low > 76
Ralstonia solanacearum UW163 0.97 UW163_RS10700 2-isopropylmalate synthase 0.93 UW163_RS14440 3-hydroxyacyl-CoA dehydrogenase — —
Ralstonia solanacearum PSI07 0.96 RPSI07_RS14285 2-isopropylmalate synthase 0.93 RPSI07_RS16345 3-hydroxyacyl-CoA dehydrogenase low > 81
Cupriavidus basilensis FW507-4G11 0.89 RR42_RS05465 2-isopropylmalate synthase 0.85 RR42_RS11095 3-hydroxyacyl-CoA dehydrogenase low > 128
Burkholderia phytofirmans PsJN 0.86 BPHYT_RS06570 2-isopropylmalate synthase 0.78 BPHYT_RS09560 3-hydroxyacyl-CoA dehydrogenase low > 109
Paraburkholderia graminis OAS925 0.85 ABIE53_001580 2-isopropylmalate synthase 0.77 ABIE53_002151 3-hydroxyacyl-CoA dehydrogenase low > 113
Paraburkholderia bryophila 376MFSha3.1 0.85 H281DRAFT_04556 2-isopropylmalate synthase 0.78 H281DRAFT_00916 short chain enoyl-CoA hydratase /3-hydroxyacyl-CoA dehydrogenase low > 103
Paraburkholderia sabiae LMG 24235 0.85 QEN71_RS24195 2-isopropylmalate synthase 0.77 QEN71_RS21890 3-hydroxyacyl-CoA dehydrogenase NAD-binding domain-containing protein low > 153
Hydrogenophaga sp. GW460-11-11-14-LB1 0.80 GFF4281 2-isopropylmalate synthase (EC 2.3.3.13) 0.71 GFF4592 Enoyl-CoA hydratase (EC 4.2.1.17) / Delta(3)-cis-delta(2)-trans-enoyl-CoA isomerase (EC 5.3.3.8) / 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35) / 3-hydroxybutyryl-CoA epimerase (EC 5.1.2.3) low > 90
Acidovorax sp. GW101-3H11 0.80 Ac3H11_530 2-isopropylmalate synthase (EC 2.3.3.13) 0.69 Ac3H11_2523 Enoyl-CoA hydratase (EC 4.2.1.17) / Delta(3)-cis-delta(2)-trans-enoyl-CoA isomerase (EC 5.3.3.8) / 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35) / 3-hydroxybutyryl-CoA epimerase (EC 5.1.2.3) low > 79
Variovorax sp. OAS795 0.79 ABID97_RS14910 2-isopropylmalate synthase 0.71 ABID97_RS15740 3-hydroxyacyl-CoA dehydrogenase NAD-binding domain-containing protein low > 91
Variovorax sp. SCN45 0.79 GFF1165 2-isopropylmalate synthase (EC 2.3.3.13) 0.71 GFF1342 Enoyl-CoA hydratase (EC 4.2.1.17) / Delta(3)-cis-delta(2)-trans-enoyl-CoA isomerase (EC 5.3.3.8) / 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35) / 3-hydroxybutyryl-CoA epimerase (EC 5.1.2.3) low > 127
Marinobacter adhaerens HP15 0.65 HP15_538 2-isopropylmalate synthase 0.51 HP15_3941 fatty oxidation complex alpha subunit low > 73
Pseudomonas stutzeri RCH2 0.63 Psest_1056 2-isopropylmalate synthase, bacterial type 0.49 Psest_4235 3-hydroxyacyl-CoA dehydrogenase low > 67
Magnetospirillum magneticum AMB-1 0.54 AMB_RS17765 2-isopropylmalate synthase 0.43 AMB_RS15050 multifunctional fatty acid oxidation complex subunit alpha low > 64
Rhodopseudomonas palustris CGA009 0.51 TX73_010545 2-isopropylmalate synthase 0.50 TX73_019255 3-hydroxyacyl-CoA dehydrogenase NAD-binding domain-containing protein low > 86
Bosea sp. OAE506 0.50 ABIE41_RS13000 2-isopropylmalate synthase 0.43 ABIE41_RS07780 3-hydroxyacyl-CoA dehydrogenase NAD-binding domain-containing protein low > 77
Caulobacter crescentus NA1000 0.49 CCNA_01610 2-isopropylmalate synthase 0.47 CCNA_03293 multifunctional fatty acid oxidation complex subunit alpha FadJ low > 66
Caulobacter crescentus NA1000 Δfur 0.49 CCNA_01610 2-isopropylmalate synthase 0.47 CCNA_03293 multifunctional fatty acid oxidation complex subunit alpha FadJ low > 67
Phaeobacter inhibens DSM 17395 0.49 PGA1_c26470 2-isopropylmalate synthase LeuA 0.43 PGA1_c22740 fatty acid oxidation complex subunit alpha low > 62
Shewanella loihica PV-4 0.46 Shew_3472 2-isopropylmalate synthase (RefSeq) 0.46 Shew_2864 3-hydroxyacyl-CoA dehydrogenase, NAD-binding (RefSeq) low > 60
Dinoroseobacter shibae DFL-12 0.46 Dshi_0596 2-isopropylmalate synthase (RefSeq) 0.33 Dshi_3826 3-hydroxyacyl-CoA dehydrogenase NAD-binding (RefSeq) low > 64
Alteromonas macleodii MIT1002 0.44 MIT1002_00949 2-isopropylmalate synthase 0.49 MIT1002_01750 Fatty acid oxidation complex subunit alpha low > 70
Escherichia fergusonii Becca 0.44 EFB2_03971 2-isopropylmalate synthase 0.21 EFB2_04771 Fatty acid oxidation complex subunit alpha low > 86
Escherichia coli ECOR27 0.44 NOLOHH_03060 2-isopropylmalate synthase 0.22 NOLOHH_06375 fadB fatty acid oxidation complex subunit alpha FadB low > 75
Escherichia coli ECRC99 0.44 KEDOAH_17440 2-isopropylmalate synthase 0.22 KEDOAH_13905 fadB fatty acid oxidation complex subunit alpha FadB — —
Escherichia coli BL21 0.44 ECD_00076 2-isopropylmalate synthase 0.21 ECD_03737 fused 3-hydroxybutyryl-CoA epimerase/delta(3)-cis-delta(2)-trans-enoyl-CoA isomerase/enoyl-CoA hydratase/3-hydroxyacyl-CoA dehydrogenase low > 61
Escherichia coli ECOR38 0.44 HEPCGN_08695 2-isopropylmalate synthase 0.22 HEPCGN_12875 fadB fatty acid oxidation complex subunit alpha FadB low > 87
Escherichia coli ECRC62 0.44 BNILDI_08550 2-isopropylmalate synthase 0.21 BNILDI_05155 fadB fatty acid oxidation complex subunit alpha FadB low > 75
Escherichia coli BW25113 0.44 b0074 leuA 2-isopropylmalate synthase (NCBI) 0.22 b3846 fadB fused 3-hydroxybutyryl-CoA epimerase/delta(3)-cis-delta(2)-trans-enoyl-CoA isomerase/enoyl-CoA hydratase/3-hydroxyacyl-CoA dehydrogenase (NCBI) low > 76
Escherichia coli ECRC102 0.44 NIAGMN_08565 2-isopropylmalate synthase 0.22 NIAGMN_12000 fadB fatty acid oxidation complex subunit alpha FadB — —
Escherichia coli ECRC101 0.44 MCAODC_01230 2-isopropylmalate synthase 0.22 MCAODC_04750 fadB fatty acid oxidation complex subunit alpha FadB low > 87
Escherichia coli ECRC100 0.44 OKFHMN_10715 2-isopropylmalate synthase 0.22 OKFHMN_14245 fadB fatty acid oxidation complex subunit alpha FadB low > 80
Escherichia coli ECRC98 0.44 JDDGAC_14310 2-isopropylmalate synthase 0.22 JDDGAC_17870 fadB fatty acid oxidation complex subunit alpha FadB low > 86
Pantoea sp. MT58 0.44 IAI47_16000 2-isopropylmalate synthase 0.23 IAI47_18230 fatty acid oxidation complex subunit alpha FadB low > 76
Pectobacterium carotovorum WPP14 0.43 HER17_RS03085 2-isopropylmalate synthase 0.23 HER17_RS20550 fatty acid oxidation complex subunit alpha FadB low > 75
Dickeya dianthicola ME23 0.43 DZA65_RS19200 2-isopropylmalate synthase 0.22 DZA65_RS01035 fatty acid oxidation complex subunit alpha FadB low > 75
Klebsiella michiganensis M5al 0.43 BWI76_RS04680 2-isopropylmalate synthase 0.21 BWI76_RS01365 multifunctional fatty acid oxidation complex subunit alpha low > 92
Dickeya dianthicola 67-19 0.43 HGI48_RS18055 2-isopropylmalate synthase 0.23 HGI48_RS00975 fatty acid oxidation complex subunit alpha FadB low > 71
Dickeya dadantii 3937 0.43 DDA3937_RS18115 2-isopropylmalate synthase 0.24 DDA3937_RS20250 fatty acid oxidation complex subunit alpha FadB low > 74

Not shown: 31 genomes with orthologs for ABZR87_RS14930 only; 10 genomes with orthologs for ABZR87_RS12585 only