Conservation of cofitness between b3292 and b3993 in Escherichia coli BW25113

44 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Escherichia coli BW25113 1.0 b3292 zntR zinc-responsive transcriptional regulator (NCBI) 1.0 b3993 thiE thiamine-phosphate pyrophosphorylase (NCBI) 0.24 18
Escherichia coli BL21 1.00 ECD_03143 zntA gene transcriptional activator 1.00 ECD_03870 thiamine phosphate synthase (thiamine phosphate pyrophosphorylase) low > 60
Escherichia coli ECRC99 1.00 KEDOAH_10640 zntR Zn(2+)-responsive transcriptional regulator 0.99 KEDOAH_14780 thiE thiamine phosphate synthase — —
Escherichia coli ECRC101 1.00 MCAODC_08030 zntR Zn(2+)-responsive transcriptional regulator 0.99 MCAODC_03880 thiE thiamine phosphate synthase — —
Escherichia coli HS(pFamp)R (ATCC 700891) 1.00 OHPLBJKB_00411 HTH-type transcriptional regulator ZntR 0.99 OHPLBJKB_04057 Thiamine-phosphate synthase low > 73
Escherichia coli ECRC62 1.00 BNILDI_02220 zntR Zn(2+)-responsive transcriptional regulator 1.00 BNILDI_06000 thiE thiamine phosphate synthase — —
Escherichia coli ECRC101 1.00 OKFHMN_17500 zntR Zn(2+)-responsive transcriptional regulator 0.99 OKFHMN_13380 thiE thiamine phosphate synthase — —
Escherichia coli ECRC102 1.00 NIAGMN_15270 zntR Zn(2+)-responsive transcriptional regulator 0.99 NIAGMN_11130 thiE thiamine phosphate synthase — —
Escherichia coli ECRC98 1.00 JDDGAC_21130 zntR Zn(2+)-responsive transcriptional regulator 0.99 JDDGAC_17005 thiE thiamine phosphate synthase — —
Escherichia coli ECOR27 1.00 NOLOHH_09300 zntR Zn(2+)-responsive transcriptional regulator 1.00 NOLOHH_05525 thiE thiamine phosphate synthase low > 57
Escherichia coli ECOR38 1.00 HEPCGN_16330 zntR Zn(2+)-responsive transcriptional regulator 0.96 HEPCGN_12015 thiE thiamine phosphate synthase low > 85
Escherichia fergusonii Becca 0.99 EFB2_00531 HTH-type transcriptional regulator ZntR 0.99 EFB2_04618 Thiamine-phosphate synthase low > 86
Escherichia coli Nissle 1917 0.99 ECOLIN_RS18895 Zn(2+)-responsive transcriptional regulator 0.98 ECOLIN_RS23035 thiamine phosphate synthase — —
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.95 GFF2387 transcriptional regulator, MerR family 0.92 GFF4199 Thiamin-phosphate pyrophosphorylase (EC 2.5.1.3) low > 78
Enterobacter asburiae PDN3 0.89 EX28DRAFT_0035 Zn(II)-responsive transcriptional regulator 0.90 EX28DRAFT_4535 thiamine-phosphate diphosphorylase low > 76
Klebsiella michiganensis M5al 0.88 BWI76_RS25700 heavy metal-responsive transcriptional regulator 0.91 BWI76_RS01550 thiamine phosphate synthase 0.42 55
Enterobacter sp. TBS_079 0.88 MPMX20_04200 HTH-type transcriptional regulator ZntR 0.89 MPMX20_00216 Thiamine-phosphate synthase low > 85
Erwinia tracheiphila SCR3 0.76 LU632_RS22515 zntR Zn(2+)-responsive transcriptional regulator 0.70 LU632_RS00965 thiE thiamine phosphate synthase low > 74
Serratia liquefaciens MT49 0.76 IAI46_23295 Zn(2+)-responsive transcriptional regulator 0.72 IAI46_01315 thiamine phosphate synthase low > 86
Pantoea sp. MT58 0.75 IAI47_02260 Zn(2+)-responsive transcriptional regulator 0.69 IAI47_18090 thiamine phosphate synthase low > 76
Rahnella sp. WP5 0.65 EX31_RS16005 Zn(2+)-responsive transcriptional regulator 0.71 EX31_RS16810 thiamine phosphate synthase low > 89
Dinoroseobacter shibae DFL-12 0.36 Dshi_3961 transcriptional regulator, MerR family (RefSeq) 0.40 Dshi_0911 Thiamine-phosphate diphosphorylase (RefSeq) — —
Pseudomonas syringae pv. syringae B728a ΔmexB 0.35 Psyr_4838 transcriptional regulator, MerR family 0.19 Psyr_4341 thiamine-phosphate diphosphorylase low > 86
Phaeobacter inhibens DSM 17395 0.35 PGA1_262p00460 transcriptional regulator, MerR family 0.34 PGA1_c09050 thiamine-phosphate pyrophosphorylase ThiE low > 62
Pseudomonas syringae pv. syringae B728a 0.35 Psyr_4838 transcriptional regulator, MerR family 0.19 Psyr_4341 thiamine-phosphate diphosphorylase low > 86
Marinobacter adhaerens HP15 0.34 HP15_89 transcriptional regulator, MerR family protein 0.13 HP15_348 thiamine-phosphate pyrophosphorylase — —
Pseudomonas stutzeri RCH2 0.33 Psest_2758 Predicted transcriptional regulators 0.19 Psest_0536 thiamine-phosphate pyrophosphorylase low > 67
Pseudomonas fluorescens SBW25 0.33 PFLU_RS28620 Cd(II)/Pb(II)-responsive transcriptional regulator 0.18 PFLU_RS26535 thiamine phosphate synthase low > 109
Pseudomonas fluorescens SBW25-INTG 0.33 PFLU_RS28620 Cd(II)/Pb(II)-responsive transcriptional regulator 0.18 PFLU_RS26535 thiamine phosphate synthase low > 109
Pseudomonas fluorescens GW456-L13 0.33 PfGW456L13_958 Cd(II)/Pb(II)-responsive transcriptional regulator 0.19 PfGW456L13_1384 Thiamin-phosphate pyrophosphorylase (EC 2.5.1.3) low > 87
Rhodopseudomonas palustris CGA009 0.33 TX73_016860 helix-turn-helix domain-containing protein 0.41 TX73_018535 thiamine phosphate synthase — —
Brevundimonas sp. GW460-12-10-14-LB2 0.33 A4249_RS03105 helix-turn-helix domain-containing protein 0.16 A4249_RS08810 thiamine phosphate synthase — —
Pseudomonas putida KT2440 0.32 PP_5140 Transcriptional regulator, MerR family 0.17 PP_4783 Thiamine-phosphate synthase — —
Pseudomonas simiae WCS417 0.32 PS417_26960 Cd(II)/Pb(II)-responsive transcriptional regulator 0.18 PS417_24605 thiamine-phosphate pyrophosphorylase — —
Pseudomonas fluorescens FW300-N2E2 0.32 Pf6N2E2_3947 Cd(II)/Pb(II)-responsive transcriptional regulator 0.17 Pf6N2E2_5023 Thiamin-phosphate pyrophosphorylase (EC 2.5.1.3) low > 103
Pseudomonas fluorescens FW300-N2C3 0.32 AO356_10375 Cd(II)/Pb(II)-responsive transcriptional regulator 0.17 AO356_15430 thiamine-phosphate pyrophosphorylase low > 104
Magnetospirillum magneticum AMB-1 0.32 AMB_RS05180 MerR family DNA-binding transcriptional regulator 0.15 AMB_RS14385 thiamine phosphate synthase — —
Pseudomonas fluorescens FW300-N2E3 0.32 AO353_08425 Cd(II)/Pb(II)-responsive transcriptional regulator 0.18 AO353_06355 thiamine-phosphate pyrophosphorylase low > 101
Pseudomonas sp. RS175 0.32 PFR28_04825 Mercuric resistance operon regulatory protein 0.18 PFR28_03844 Thiamine-phosphate synthase low > 88
Pseudomonas fluorescens FW300-N1B4 0.32 Pf1N1B4_2290 Cd(II)/Pb(II)-responsive transcriptional regulator 0.18 Pf1N1B4_2717 Thiamin-phosphate pyrophosphorylase (EC 2.5.1.3) — —
Bosea sp. OAE506 0.31 ABIE41_RS05340 helix-turn-helix domain-containing protein 0.40 ABIE41_RS20180 thiamine phosphate synthase — —
Dickeya dadantii 3937 0.31 DDA3937_RS02550 Cd(II)/Pb(II)-responsive transcriptional regulator 0.69 DDA3937_RS01170 thiamine phosphate synthase low > 74
Dickeya dianthicola ME23 0.30 DZA65_RS02685 Cd(II)/Pb(II)-responsive transcriptional regulator 0.66 DZA65_RS01210 thiamine phosphate synthase low > 75
Dickeya dianthicola 67-19 0.30 HGI48_RS02580 Cd(II)/Pb(II)-responsive transcriptional regulator 0.68 HGI48_RS01165 thiamine phosphate synthase low > 71
Mycobacterium tuberculosis H37Rv 0.24 Rv3334 Probable transcriptional regulatory protein (probably MerR-family) 0.19 Rv0414c Thiamine-phosphate pyrophosphorylase ThiE (TMP pyrophosphorylase) (TMP-PPASE) (thiamine-phosphate synthase) — —

Not shown: 14 genomes with orthologs for b3292 only; 26 genomes with orthologs for b3993 only