Conservation of cofitness between b2688 and b0464 in Escherichia coli BW25113

47 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Escherichia coli BW25113 1.0 b2688 gshA glutamate--cysteine ligase (NCBI) 1.0 b0464 acrR DNA-binding transcriptional repressor (NCBI) 0.40 4
Escherichia coli BL21 1.00 ECD_02543 glutamate-cysteine ligase 1.00 ECD_00415 transcriptional repressor low > 60
Escherichia coli HS(pFamp)R (ATCC 700891) 1.00 OHPLBJKB_01045 Glutamate--cysteine ligase 1.00 OHPLBJKB_03210 HTH-type transcriptional regulator AcrR low > 73
Escherichia coli Nissle 1917 1.00 ECOLIN_RS14990 glutamate--cysteine ligase 1.00 ECOLIN_RS02760 multidrug efflux transporter transcriptional repressor AcrR low > 52
Escherichia fergusonii Becca 1.00 EFB2_01238 Glutamate--cysteine ligase 1.00 EFB2_03594 HTH-type transcriptional regulator AcrR low > 86
Escherichia coli ECRC101 1.00 MCAODC_11285 gshA glutamate--cysteine ligase 1.00 MCAODC_27420 acrR multidrug efflux transporter transcriptional repressor AcrR
Escherichia coli ECRC99 1.00 KEDOAH_07375 gshA glutamate--cysteine ligase 1.00 KEDOAH_19770 acrR multidrug efflux transporter transcriptional repressor AcrR
Escherichia coli ECRC102 1.00 NIAGMN_18530 gshA glutamate--cysteine ligase 0.99 NIAGMN_06250 acrR multidrug efflux transporter transcriptional repressor AcrR
Escherichia coli ECRC101 1.00 OKFHMN_20760 gshA glutamate--cysteine ligase 0.99 OKFHMN_08195 acrR multidrug efflux transporter transcriptional repressor AcrR
Escherichia coli ECOR38 1.00 HEPCGN_19955 gshA glutamate--cysteine ligase 1.00 HEPCGN_06810 acrR multidrug efflux transporter transcriptional repressor AcrR low > 85
Escherichia coli ECRC98 1.00 JDDGAC_24425 gshA glutamate--cysteine ligase 1.00 JDDGAC_11845 acrR multidrug efflux transporter transcriptional repressor AcrR
Escherichia coli ECRC62 0.99 BNILDI_11160 gshA glutamate--cysteine ligase 1.00 BNILDI_22545 acrR multidrug efflux transporter transcriptional repressor AcrR
Escherichia coli ECOR27 0.99 NOLOHH_12600 gshA glutamate--cysteine ligase 1.00 NOLOHH_01130 acrR multidrug efflux transporter transcriptional repressor AcrR low > 57
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.95 GFF1597 Glutamate--cysteine ligase (EC 6.3.2.2) 0.88 GFF4381 Transcription repressor of multidrug efflux pump acrAB operon, TetR (AcrR) family low > 78
Klebsiella michiganensis M5al 0.88 BWI76_RS22120 glutamate--cysteine ligase 0.80 BWI76_RS06785 DNA-binding transcriptional repressor AcrR 0.69 6
Enterobacter sp. TBS_079 0.88 MPMX20_03568 Glutamate--cysteine ligase 0.72 MPMX20_01066 HTH-type transcriptional regulator AcrR low > 85
Enterobacter asburiae PDN3 0.88 EX28DRAFT_2774 glutamate-cysteine ligase (EC 6.3.2.2) 0.83 EX28DRAFT_2494 transcriptional regulator, TetR family low > 76
Serratia liquefaciens MT49 0.76 IAI46_03895 glutamate--cysteine ligase 0.66 IAI46_05195 multidrug efflux transporter transcriptional repressor AcrR low > 86
Pectobacterium carotovorum WPP14 0.74 HER17_RS05095 glutamate--cysteine ligase 0.59 HER17_RS15730 multidrug efflux transporter transcriptional repressor AcrR low > 75
Rahnella sp. WP5 0.74 EX31_RS07750 glutamate--cysteine ligase 0.59 EX31_RS22480 multidrug efflux transporter transcriptional repressor AcrR low > 89
Dickeya dadantii 3937 0.74 DDA3937_RS16195 glutamate--cysteine ligase 0.59 DDA3937_RS05745 multidrug efflux transporter transcriptional repressor AcrR low > 74
Dickeya dianthicola 67-19 0.72 HGI48_RS16305 glutamate--cysteine ligase 0.58 HGI48_RS05800 multidrug efflux transporter transcriptional repressor AcrR 0.58 39
Dickeya dianthicola ME23 0.72 DZA65_RS17400 glutamate--cysteine ligase 0.59 DZA65_RS06125 multidrug efflux transporter transcriptional repressor AcrR low > 75
Pantoea sp. MT58 0.70 IAI47_04350 glutamate--cysteine ligase 0.60 IAI47_14505 multidrug efflux transporter transcriptional repressor AcrR low > 76
Erwinia tracheiphila SCR3 0.70 LU632_RS15690 gshA glutamate--cysteine ligase 0.59 LU632_RS18175 acrR multidrug efflux transporter transcriptional repressor AcrR low > 74
Pseudomonas sp. RS175 0.38 PFR28_04865 Glutamate--cysteine ligase 0.38 PFR28_00633 HTH-type transcriptional regulator TtgR low > 88
Pseudomonas sp. S08-1 0.37 OH686_11110 glutamate--cysteine ligase 0.38 OH686_16040 Transcriptional regulator, AcrR family 0.67 64
Pseudomonas fluorescens FW300-N2E3 0.37 AO353_11730 glutamate--cysteine ligase 0.39 AO353_17305 TetR family transcriptional regulator low > 101
Pseudomonas putida KT2440 0.37 PP_0243 Glutamate--cysteine ligase 0.35 PP_1387 Probable HTH-type transcriptional regulator TtgR
Pseudomonas fluorescens FW300-N2C3 0.37 AO356_10185 glutamate--cysteine ligase 0.38 AO356_04870 TetR family transcriptional regulator 0.34 29
Burkholderia phytofirmans PsJN 0.37 BPHYT_RS00520 glutamate--cysteine ligase 0.37 BPHYT_RS16180 TetR family transcriptional regulator low > 109
Pseudomonas fluorescens FW300-N2E2 0.37 Pf6N2E2_3908 Glutamate--cysteine ligase (EC 6.3.2.2) 0.37 Pf6N2E2_2822 Transcription repressor of multidrug efflux pump acrAB operon, TetR (AcrR) family low > 103
Pseudomonas fluorescens FW300-N1B4 0.37 Pf1N1B4_1769 Glutamate--cysteine ligase (EC 6.3.2.2) 0.39 Pf1N1B4_3248 Transcription repressor of multidrug efflux pump acrAB operon, TetR (AcrR) family
Pseudomonas fluorescens GW456-L13 0.37 PfGW456L13_430 Glutamate--cysteine ligase (EC 6.3.2.2) 0.36 PfGW456L13_4579 Transcription repressor of multidrug efflux pump acrAB operon, TetR (AcrR) family 0.30 49
Pseudomonas simiae WCS417 0.36 PS417_01155 glutamate--cysteine ligase 0.38 PS417_06780 TetR family transcriptional regulator
Pseudomonas fluorescens SBW25 0.36 PFLU_RS01265 glutamate--cysteine ligase 0.39 PFLU_RS06815 TetR family transcriptional regulator
Pseudomonas fluorescens SBW25-INTG 0.36 PFLU_RS01265 glutamate--cysteine ligase 0.39 PFLU_RS06815 TetR family transcriptional regulator
Pseudomonas syringae pv. syringae B728a ΔmexB 0.35 Psyr_0255 glutamate-cysteine ligase 0.37 Psyr_4006 transcriptional regulator, TetR family
Pseudomonas syringae pv. syringae B728a 0.35 Psyr_0255 glutamate-cysteine ligase 0.37 Psyr_4006 transcriptional regulator, TetR family low > 86
Herbaspirillum seropedicae SmR1 0.35 HSERO_RS07300 glutamate--cysteine ligase 0.34 HSERO_RS02420 TetR family transcriptional regulator
Variovorax sp. OAS795 0.34 ABID97_RS20965 glutamate--cysteine ligase 0.29 ABID97_RS00315 TetR family transcriptional regulator low > 91
Paraburkholderia bryophila 376MFSha3.1 0.34 H281DRAFT_02339 glutamate-cysteine ligase 0.35 H281DRAFT_04172 transcriptional regulator, TetR family low > 103
Hydrogenophaga sp. GW460-11-11-14-LB1 0.33 GFF3561 Glutamate--cysteine ligase (EC 6.3.2.2) 0.30 GFF3838 Transcription repressor of multidrug efflux pump acrAB operon, TetR (AcrR) family low > 90
Paraburkholderia sabiae LMG 24235 0.33 QEN71_RS29600 glutamate--cysteine ligase 0.36 QEN71_RS02515 TetR family transcriptional regulator low > 153
Marinobacter adhaerens HP15 0.33 HP15_217 glutamate--cysteine ligase 0.22 HP15_3151 transcriptional regulator, TetR family
Variovorax sp. SCN45 0.32 GFF7064 Glutamate--cysteine ligase (EC 6.3.2.2) 0.27 GFF3727 Transcriptional regulator, AcrR family low > 127
Paraburkholderia graminis OAS925 0.32 ABIE53_000313 glutamate--cysteine ligase 0.35 ABIE53_003410 TetR/AcrR family acrAB operon transcriptional repressor low > 113
Acidovorax sp. GW101-3H11 0.31 Ac3H11_3126 Glutamate--cysteine ligase (EC 6.3.2.2) 0.28 Ac3H11_4450 Transcription repressor of multidrug efflux pump acrAB operon, TetR (AcrR) family low > 79

Not shown: 10 genomes with orthologs for b2688 only; 10 genomes with orthologs for b0464 only