Conservation of cofitness between SMc02558 and SMc02659 in Sinorhizobium meliloti 1021

37 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Sinorhizobium meliloti 1021 1.0 SMc02558 hypothetical protein 1.0 SMc02659 GTP pyrophosphokinase (ATP:GTP 3'-pyrophosphotransferase) protein 0.81 1
Rhizobium sp. OAE497 0.57 ABIE40_RS06145 folate-binding protein YgfZ 0.83 ABIE40_RS06050 bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase low > 107
Agrobacterium fabrum C58 0.49 Atu1053 glycine cleavage system T protein, aminomethyltransferase 0.85 Atu1030 GTP pyrophosphohydrolase/synthetase, RelA/SpoT family
Bosea sp. OAE506 0.33 ABIE41_RS09695 folate-binding protein YgfZ 0.59 ABIE41_RS19890 bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase low > 77
Rhodopseudomonas palustris CGA009 0.29 TX73_005490 folate-binding protein YgfZ 0.58 TX73_013955 bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase low > 86
Dinoroseobacter shibae DFL-12 0.24 Dshi_2092 glycine cleavage T protein (aminomethyl transferase) (RefSeq) 0.39 Dshi_0194 (p)ppGpp synthetase I, SpoT/RelA (RefSeq) low > 64
Brevundimonas sp. GW460-12-10-14-LB2 0.23 A4249_RS09495 folate-binding protein YgfZ 0.41 A4249_RS05505 bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase
Azospirillum brasilense Sp245 0.23 AZOBR_RS06940 glycine cleavage system protein T 0.49 AZOBR_RS22045 GTP pyrophosphokinase low > 97
Caulobacter crescentus NA1000 Δfur 0.22 CCNA_00389 aminomethyltransferase family protein 0.43 CCNA_01622 Rsh ppGpp hydrolase-synthetase low > 67
Caulobacter crescentus NA1000 0.22 CCNA_00389 aminomethyltransferase family protein 0.43 CCNA_01622 Rsh ppGpp hydrolase-synthetase 0.50 55
Azospirillum sp. SherDot2 0.22 MPMX19_01714 tRNA-modifying protein YgfZ 0.48 MPMX19_00838 GTP pyrophosphokinase rsh low > 112
Phaeobacter inhibens DSM 17395 0.22 PGA1_c23960 tRNA-modifying protein ygfZ-like protein 0.38 PGA1_c01010 guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase SpoT
Rhodospirillum rubrum S1H 0.17 Rru_A2940 Glycine cleavage T protein (aminomethyl transferase) (NCBI) 0.46 Rru_A1856 (p)ppGpp synthetase I (GTP pyrophosphokinase), SpoT/RelA (NCBI)
Kangiella aquimarina DSM 16071 0.14 B158DRAFT_2176 folate-binding protein YgfZ 0.32 B158DRAFT_0574 (p)ppGpp synthetase, RelA/SpoT family
Escherichia coli ECOR38 0.14 HEPCGN_18840 ygfZ tRNA-modifying protein YgfZ 0.31 HEPCGN_14375 spoT bifunctional GTP diphosphokinase/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase
Escherichia coli ECOR27 0.14 NOLOHH_11475 ygfZ tRNA-modifying protein YgfZ 0.31 NOLOHH_07435 spoT bifunctional GTP diphosphokinase/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase
Escherichia coli HS(pFamp)R (ATCC 700891) 0.13 OHPLBJKB_00817 tRNA-modifying protein YgfZ 0.31 OHPLBJKB_00051 Bifunctional (p)ppGpp synthase/hydrolase SpoT
Escherichia coli Nissle 1917 0.13 ECOLIN_RS16145 tRNA-modifying protein YgfZ 0.31 ECOLIN_RS20790 bifunctional GTP diphosphokinase/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase
Escherichia coli ECRC62 0.13 BNILDI_10005 ygfZ tRNA-modifying protein YgfZ 0.31 BNILDI_04080 spoT bifunctional GTP diphosphokinase/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase
Escherichia coli BW25113 0.13 b2898 ygfZ putative global regulator (NCBI) 0.31 b3650 spoT bifunctional (p)ppGpp synthetase II/ guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase (NCBI)
Escherichia coli BL21 0.13 ECD_02730 iron-sulfur cluster repair protein, plumbagin resistance 0.31 ECD_03507 bifunctional (p)ppGpp synthetase II/ guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase
Escherichia fergusonii Becca 0.13 EFB2_01003 tRNA-modifying protein YgfZ 0.31 EFB2_00138 Bifunctional (p)ppGpp synthase/hydrolase SpoT
Shewanella amazonensis SB2B 0.13 Sama_2950 hypothetical protein (RefSeq) 0.31 Sama_0264 bifunctional (p)ppGpp synthetase II/ guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase (RefSeq)
Escherichia coli ECRC99 0.13 KEDOAH_08590 ygfZ tRNA-modifying protein YgfZ 0.31 KEDOAH_12590 spoT bifunctional GTP diphosphokinase/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase
Escherichia coli ECRC98 0.13 JDDGAC_23190 ygfZ tRNA-modifying protein YgfZ 0.31 JDDGAC_19180 spoT bifunctional GTP diphosphokinase/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase
Escherichia coli ECRC101 0.13 MCAODC_10070 ygfZ tRNA-modifying protein YgfZ 0.31 MCAODC_06065 spoT bifunctional GTP diphosphokinase/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase
Escherichia coli ECRC101 0.13 OKFHMN_19550 ygfZ tRNA-modifying protein YgfZ 0.31 OKFHMN_15555 spoT bifunctional GTP diphosphokinase/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase
Escherichia coli ECRC102 0.13 NIAGMN_17315 ygfZ tRNA-modifying protein YgfZ 0.31 NIAGMN_13315 spoT bifunctional GTP diphosphokinase/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase
Cupriavidus basilensis FW507-4G11 0.13 RR42_RS10915 folate-binding protein 0.32 RR42_RS04920 guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase
Pseudomonas fluorescens GW456-L13 0.13 PfGW456L13_4521 Folate-dependent protein for Fe/S cluster synthesis/repair in oxidative stress 0.32 PfGW456L13_780 GTP pyrophosphokinase (EC 2.7.6.5), (p)ppGpp synthetase II / Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase (EC 3.1.7.2)
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.12 GFF2996 Folate-dependent protein for Fe/S cluster synthesis/repair in oxidative stress 0.31 GFF357 'GTP pyrophosphokinase (EC 2.7.6.5), (p)ppGpp synthetase II / Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase (EC 3.1.7.2)' transl_table=11
Pseudomonas fluorescens SBW25-INTG 0.12 PFLU_RS07175 folate-binding protein YgfZ 0.32 PFLU_RS29510 bifunctional GTP diphosphokinase/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase
Pseudomonas fluorescens SBW25 0.12 PFLU_RS07175 folate-binding protein YgfZ 0.32 PFLU_RS29510 bifunctional GTP diphosphokinase/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase
Marinobacter adhaerens HP15 0.11 HP15_771 glycine cleavage T-protein (aminomethyl transferase) 0.30 HP15_305 guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase low > 73
Pseudomonas fluorescens FW300-N2E2 0.11 Pf6N2E2_2762 Folate-dependent protein for Fe/S cluster synthesis/repair in oxidative stress 0.32 Pf6N2E2_4361 GTP pyrophosphokinase (EC 2.7.6.5), (p)ppGpp synthetase II / Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase (EC 3.1.7.2)
Pseudomonas fluorescens FW300-N2C3 0.11 AO356_04595 aminomethyltransferase 0.32 AO356_12480 (p)ppGpp synthetase
Lysobacter sp. OAE881 0.10 ABIE51_RS12540 folate-binding protein YgfZ 0.31 ABIE51_RS17265 bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase
Xanthomonas campestris pv. campestris strain 8004 0.10 Xcc-8004.2453.1 Folate-dependent protein for Fe/S cluster synthesis/repair in oxidative stress 0.30 Xcc-8004.1215.1 GTP pyrophosphokinase (EC 2.7.6.5), (p)ppGpp synthetase II / Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase (EC 3.1.7.2)

Not shown: 0 genomes with orthologs for SMc02558 only; 64 genomes with orthologs for SMc02659 only