| Organism | Ratio1 | Gene1 | Name1 | Description1 | Ratio2 | Gene2 | Name2 | Description2 | Cofit | Rank |
| Pseudomonas syringae pv. syringae B728a | 1.0 | Psyr_0059 | | HemY, N-terminal:HemY, N-terminal:HemY, N-terminal | 1.0 | Psyr_0811 | | Integral membrane protein TerC | 0.46 | 5 |
| Pseudomonas syringae pv. syringae B728a ΔmexB | 1.00 | Psyr_0059 | | HemY, N-terminal:HemY, N-terminal:HemY, N-terminal | 1.00 | Psyr_0811 | | Integral membrane protein TerC | low | > 86 |
| Pseudomonas sp. DMC3 | 0.73 | GFF355 | | Protein HemY | 0.24 | GFF1785 | | Putative membrane-bound redox modulator Alx | low | > 89 |
| Pseudomonas sp. RS175 | 0.71 | PFR28_04363 | | Protein HemY | 0.23 | PFR28_02552 | | Putative membrane-bound redox modulator Alx | low | > 88 |
| Pseudomonas fluorescens FW300-N1B4 | 0.69 | Pf1N1B4_2188 | | Uncharacterized protein EC-HemY, likely associated with heme metabolism based on gene clustering with hemC, hemD in Proteobacteria (unrelated to HemY-type PPO in GramPositives) | 0.24 | Pf1N1B4_5047 | | Integral membrane protein TerC | — | — |
| Pseudomonas sp. SVBP6 | 0.68 | COO64_RS01180 | | heme biosynthesis protein HemY | 0.25 | COO64_RS24415 | | TerC family protein | low | > 93 |
| Pseudomonas fluorescens GW456-L13 | 0.68 | PfGW456L13_859 | | Uncharacterized protein EC-HemY, likely associated with heme metabolism based on gene clustering with hemC, hemD in Proteobacteria (unrelated to HemY-type PPO in GramPositives) | 0.22 | PfGW456L13_2898 | | Integral membrane protein TerC | low | > 87 |
| Pseudomonas putida KT2440 | 0.63 | PP_0189 | | putative heme biosynthesis protein | 0.26 | PP_2438 | | putative alcaline-induced transporter | low | > 96 |
| Pseudomonas sp. BP01 | 0.63 | JOY50_RS18735 | | heme biosynthesis protein HemY | 0.26 | JOY50_RS04700 | | TerC family protein | — | — |
| Pseudomonas segetis P6 | 0.55 | MPMX49_04518 | | Protein HemY | 0.85 | MPMX49_01886 | | hypothetical protein | low | > 75 |
| Pseudomonas sp. S08-1 | 0.46 | OH686_13915 | | Uncharacterized protein EC-HemY in Proteobacteria (unrelated to HemY-type PPO in GramPositives) | 0.27 | OH686_00895 | | Integral membrane protein TerC | low | > 80 |
| Pseudomonas aeruginosa PA14 | 0.45 | IKLFDK_27170 | | heme biosynthesis protein HemY | 0.25 | IKLFDK_12530 | | Integral membrane protein TerC family | low | > 100 |
| Vibrio cholerae E7946 ATCC 55056 | 0.17 | CSW01_00595 | | heme biosynthesis protein HemY | 0.26 | CSW01_16960 | | DUF475 domain-containing protein | low | > 62 |
| Rahnella sp. WP5 | 0.15 | EX31_RS15130 | | protoheme IX biogenesis protein HemY | 0.67 | EX31_RS07195 | | TerC/Alx family metal homeostasis membrane protein | low | > 89 |
| Serratia liquefaciens MT49 | 0.15 | IAI46_00680 | | protoheme IX biogenesis protein HemY | 0.23 | IAI46_22205 | | TerC family protein | low | > 86 |
| Escherichia coli ECRC62 | 0.15 | BNILDI_04925 | hemY | protoheme IX biogenesis protein HemY | 0.24 | BNILDI_01175 | alx | TerC family membrane protein Alx | low | > 75 |
| Escherichia coli ECRC101 | 0.15 | MCAODC_04970 | hemY | protoheme IX biogenesis protein HemY | 0.73 | MCAODC_23485 | terC | tellurium resistance membrane protein TerC | low | > 88 |
| Escherichia coli BW25113 | 0.15 | b3802 | hemY | predicted protoheme IX synthesis protein (NCBI) | 0.24 | b3088 | alx | predicted inner membrane protein, part of terminus (NCBI) | low | > 76 |
| Escherichia coli ECRC100 | 0.15 | OKFHMN_14465 | hemY | protoheme IX biogenesis protein HemY | 0.73 | OKFHMN_04135 | terC | tellurium resistance membrane protein TerC | low | > 79 |
| Escherichia coli ECOR27 | 0.15 | NOLOHH_06610 | hemY | protoheme IX biogenesis protein HemY | 0.24 | NOLOHH_10340 | alx | TerC family membrane protein Alx | low | > 76 |
| Escherichia coli ECRC99 | 0.15 | KEDOAH_13685 | hemY | protoheme IX biogenesis protein HemY | 0.73 | KEDOAH_23635 | terC | tellurium resistance membrane protein TerC | — | — |
| Escherichia coli Nissle 1917 | 0.15 | ECOLIN_RS21820 | | protoheme IX biogenesis protein HemY | 0.24 | ECOLIN_RS17810 | | TerC family membrane protein Alx | low | > 55 |
| Escherichia coli ECRC98 | 0.15 | JDDGAC_18090 | hemY | protoheme IX biogenesis protein HemY | 0.73 | JDDGAC_07725 | terC | tellurium resistance membrane protein TerC | low | > 87 |
| Escherichia coli ECOR38 | 0.15 | HEPCGN_13185 | hemY | protoheme IX biogenesis protein HemY | 0.24 | HEPCGN_17395 | alx | TerC family membrane protein Alx | low | > 88 |
| Escherichia coli BL21 | 0.15 | ECD_03677 | | putative protoheme IX synthesis protein | 0.24 | ECD_02957 | | putative membrane-bound redox modulator | low | > 61 |
| Escherichia coli HS(pFamp)R (ATCC 700891) | 0.15 | OHPLBJKB_04251 | | Protein HemY | 0.24 | OHPLBJKB_00614 | | Putative membrane-bound redox modulator Alx | low | > 74 |
| Escherichia fergusonii Becca | 0.15 | EFB2_04836 | | Protein HemY | 0.24 | EFB2_00724 | | Putative membrane-bound redox modulator Alx | low | > 86 |
| Escherichia coli ECRC102 | 0.15 | NIAGMN_12220 | hemY | protoheme IX biogenesis protein HemY | 0.73 | NIAGMN_03565 | terC | tellurium resistance membrane protein TerC | low | > 80 |
| Enterobacter sp. TBS_079 | 0.15 | MPMX20_04473 | | Protein HemY | 0.66 | MPMX20_04386 | | Putative membrane-bound redox modulator Alx | low | > 85 |
| Pantoea sp. MT58 | 0.14 | IAI47_18440 | | protoheme IX biogenesis protein HemY | 0.26 | IAI47_02930 | | TerC family protein | low | > 76 |
| Pantoea agglomerans CFBP13505 P0401 | 0.14 | PagCFBP13505_RS15420 | | protoheme IX biogenesis protein HemY | 0.26 | PagCFBP13505_RS11540 | | TerC family protein | low | > 74 |
| Erwinia tracheiphila SCR3 | 0.14 | LU632_RS24175 | hemY | protoheme IX biogenesis protein HemY | 0.25 | LU632_RS02315 | | TerC family protein | low | > 74 |
| Erwinia tracheiphila HP pepo 2.2 | 0.14 | IJEDHG_08815 | hemY | protoheme IX biogenesis protein HemY | 0.25 | IJEDHG_06595 | | Integral membrane protein TerC family | low | > 61 |
| Pectobacterium carotovorum WPP14 | 0.14 | HER17_RS01300 | | protoheme IX biogenesis protein HemY | 0.24 | HER17_RS18690 | | TerC family protein | low | > 75 |
| Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 | 0.14 | GFF226 | | Uncharacterized protein EC-HemY, likely associated with heme metabolism based on gene clustering with hemC, hemD in Proteobacteria (unrelated to HemY-type PPO in GramPositives) | 0.24 | GFF3190 | | Integral membrane protein TerC | low | > 78 |
| Enterobacter asburiae PDN3 | 0.14 | EX28DRAFT_4471 | | heme biosynthesis-associated TPR protein | 0.66 | EX28DRAFT_4076 | | integral membrane protein, TerC family | low | > 76 |
| Klebsiella michiganensis M5al | 0.14 | BWI76_RS01165 | | protoheme IX biogenesis protein HemY | 0.23 | BWI76_RS24710 | | membrane protein | low | > 92 |
| Klebsiella pneumoniae MKP103 | 0.14 | KDGMDA_09655 | | protoheme IX biogenesis protein HemY | 0.23 | KDGMDA_05575 | | Integral membrane protein TerC family | low | > 95 |
| Dechlorosoma suillum PS | 0.13 | Dsui_1599 | | putative enzyme of heme biosynthesis | 0.22 | Dsui_3091 | | integral membrane protein, TerC family | low | > 51 |
| Herbaspirillum seropedicae SmR1 | 0.12 | HSERO_RS14650 | | porphyrin biosynthesis protein | 0.24 | HSERO_RS19605 | | membrane protein | — | — |
| Dickeya dadantii 3937 | 0.12 | DDA3937_RS19935 | | protoheme IX biogenesis protein HemY | 0.25 | DDA3937_RS02845 | | TerC family protein | low | > 74 |
| Dickeya dianthicola ME23 | 0.11 | DZA65_RS21135 | | protoheme IX biogenesis protein HemY | 0.24 | DZA65_RS02990 | | TerC family protein | low | > 75 |
| Dickeya dianthicola 67-19 | 0.11 | HGI48_RS20090 | | protoheme IX biogenesis protein HemY | 0.25 | HGI48_RS02820 | | TerC family protein | low | > 71 |
| Shewanella amazonensis SB2B | 0.10 | Sama_3257 | | HemY protein (RefSeq) | 0.23 | Sama_0510 | | hypothetical protein (RefSeq) | low | > 62 |
| Shewanella oneidensis MR-1 | 0.09 | SO4316 | | hemY protein, putative (NCBI ptt file) | 0.26 | SO1747 | | membrane protein, putative (NCBI ptt file) | — | — |
| Shewanella sp. ANA-3 | 0.09 | Shewana3_0383 | | HemY domain-containing protein (RefSeq) | 0.27 | Shewana3_2710 | | integral membrane protein TerC (RefSeq) | low | > 73 |
Not shown: 24 genomes with orthologs for Psyr_0059 only; 20 genomes with orthologs for Psyr_0811 only