Conservation of cofitness between OKFHMN_10730 and OKFHMN_11110 in Escherichia coli ECRC100

41 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Escherichia coli ECRC100 1.0 OKFHMN_10730 leuD 3-isopropylmalate dehydratase small subunit 1.0 OKFHMN_11110 thrA bifunctional aspartate kinase/homoserine dehydrogenase I 0.97 2
Escherichia coli ECRC98 1.00 JDDGAC_14325 leuD 3-isopropylmalate dehydratase small subunit 1.00 JDDGAC_14705 thrA bifunctional aspartate kinase/homoserine dehydrogenase I 0.91 19
Escherichia coli ECRC102 1.00 NIAGMN_08580 leuD 3-isopropylmalate dehydratase small subunit 1.00 NIAGMN_08960 thrA bifunctional aspartate kinase/homoserine dehydrogenase I — —
Escherichia coli ECRC101 1.00 MCAODC_01245 leuD 3-isopropylmalate dehydratase small subunit 1.00 MCAODC_01625 thrA bifunctional aspartate kinase/homoserine dehydrogenase I 0.82 53
Escherichia coli ECRC99 1.00 KEDOAH_17425 leuD 3-isopropylmalate dehydratase small subunit 1.00 KEDOAH_17045 thrA bifunctional aspartate kinase/homoserine dehydrogenase I — —
Escherichia coli BW25113 0.99 b0071 leuD isopropylmalate isomerase small subunit (NCBI) 1.00 b0002 thrA bifunctional aspartokinase I/homeserine dehydrogenase I (NCBI) 0.90 37
Escherichia coli BL21 0.99 ECD_00073 3-isopropylmalate dehydratase small subunit 1.00 ECD_00002 Bifunctional aspartokinase/homoserine dehydrogenase 1 0.92 7
Escherichia coli ECOR27 0.99 NOLOHH_03075 leuD 3-isopropylmalate dehydratase small subunit 1.00 NOLOHH_03440 thrA bifunctional aspartate kinase/homoserine dehydrogenase I 0.91 14
Escherichia coli ECRC62 0.99 BNILDI_08535 leuD 3-isopropylmalate dehydratase small subunit 1.00 BNILDI_08160 thrA bifunctional aspartate kinase/homoserine dehydrogenase I 0.95 19
Escherichia fergusonii Becca 0.99 EFB2_03974 3-isopropylmalate dehydratase small subunit 1.00 EFB2_04041 Bifunctional aspartokinase/homoserine dehydrogenase 1 low > 86
Escherichia coli Nissle 1917 0.99 ECOLIN_RS00385 3-isopropylmalate dehydratase small subunit 0.99 ECOLIN_RS00010 bifunctional aspartate kinase/homoserine dehydrogenase I low > 55
Escherichia coli ECOR38 0.99 HEPCGN_08710 leuD 3-isopropylmalate dehydratase small subunit 1.00 HEPCGN_09115 thrA bifunctional aspartate kinase/homoserine dehydrogenase I 0.92 10
Escherichia coli HS(pFamp)R (ATCC 700891) 0.98 OHPLBJKB_03586 3-isopropylmalate dehydratase small subunit 1.00 OHPLBJKB_03658 Bifunctional aspartokinase/homoserine dehydrogenase 1 low > 73
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.92 GFF167 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33) 0.93 GFF1078 Aspartokinase (EC 2.7.2.4) / Homoserine dehydrogenase (EC 1.1.1.3) low > 78
Enterobacter sp. TBS_079 0.89 MPMX20_00766 3-isopropylmalate dehydratase small subunit 1 0.90 MPMX20_00710 Bifunctional aspartokinase/homoserine dehydrogenase 1 0.93 11
Enterobacter asburiae PDN3 0.89 EX28DRAFT_3667 3-isopropylmalate dehydratase, small subunit 0.90 EX28DRAFT_3614 aspartate kinase (EC 2.7.2.4) 0.67 42
Klebsiella michiganensis M5al 0.87 BWI76_RS04665 3-isopropylmalate dehydratase small subunit 0.92 BWI76_RS04245 bifunctional aspartate kinase/homoserine dehydrogenase I 0.96 6
Rahnella sp. WP5 0.83 EX31_RS03695 3-isopropylmalate dehydratase small subunit 0.84 EX31_RS03945 bifunctional aspartate kinase/homoserine dehydrogenase I 0.96 20
Dickeya dadantii 3937 0.83 DDA3937_RS18130 3-isopropylmalate dehydratase small subunit 0.80 DDA3937_RS18415 bifunctional aspartate kinase/homoserine dehydrogenase I 0.71 27
Dickeya dianthicola ME23 0.82 DZA65_RS19215 3-isopropylmalate dehydratase small subunit 0.79 DZA65_RS19485 bifunctional aspartate kinase/homoserine dehydrogenase I 0.84 14
Dickeya dianthicola 67-19 0.82 HGI48_RS18070 3-isopropylmalate dehydratase small subunit 0.79 HGI48_RS18345 bifunctional aspartate kinase/homoserine dehydrogenase I 0.77 16
Pectobacterium carotovorum WPP14 0.80 HER17_RS03070 3-isopropylmalate dehydratase small subunit 0.83 HER17_RS02795 bifunctional aspartate kinase/homoserine dehydrogenase I 0.91 51
Serratia liquefaciens MT49 0.80 IAI46_03340 3-isopropylmalate dehydratase small subunit 0.82 IAI46_03030 bifunctional aspartate kinase/homoserine dehydrogenase I low > 86
Pantoea sp. MT58 0.79 IAI47_16015 3-isopropylmalate dehydratase small subunit 0.84 IAI47_16215 bifunctional aspartate kinase/homoserine dehydrogenase I 0.95 20
Erwinia tracheiphila SCR3 0.72 LU632_RS02865 leuD 3-isopropylmalate dehydratase small subunit 0.81 LU632_RS02610 thrA bifunctional aspartate kinase/homoserine dehydrogenase I 0.80 13
Vibrio cholerae E7946 ATCC 55056 0.72 CSW01_12610 3-isopropylmalate dehydratase small subunit 0.61 CSW01_11975 bifunctional aspartate kinase/homoserine dehydrogenase I low > 62
Shewanella loihica PV-4 0.61 Shew_3469 isopropylmalate isomerase small subunit (RefSeq) 0.57 Shew_1079 thrA bifunctional aspartokinase I/homeserine dehydrogenase I (RefSeq) 0.97 15
Xanthomonas campestris pv. campestris strain 8004 0.60 Xcc-8004.1050.1 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33) 0.34 Xcc-8004.2957.1 Aspartokinase (EC 2.7.2.4) / Homoserine dehydrogenase (EC 1.1.1.3) 0.73 42
Alteromonas macleodii MIT1002 0.59 MIT1002_00946 3-isopropylmalate dehydratase small subunit 1 0.52 MIT1002_03086 Aspartokinase I/homoserine dehydrogenase I 0.94 34
Shewanella sp. ANA-3 0.58 Shewana3_3758 leuD isopropylmalate isomerase small subunit (RefSeq) 0.56 Shewana3_1139 thrA bifunctional aspartokinase I/homeserine dehydrogenase I (RefSeq) 0.93 24
Shewanella oneidensis MR-1 0.58 SO4233 leuD 3-isopropylmalate dehydratase, small subunit (NCBI ptt file) 0.55 SO3415 thrA aspartokinase I/homoserine dehydrogenase, threonine-sensitive (NCBI ptt file) low > 76
Shewanella amazonensis SB2B 0.58 Sama_0338 leuD isopropylmalate isomerase small subunit (RefSeq) 0.53 Sama_0905 thrA bifunctional aspartokinase I/homeserine dehydrogenase I (RefSeq) 0.90 45
Pedobacter sp. GW460-11-11-14-LB5 0.42 CA265_RS15840 3-isopropylmalate dehydratase small subunit 0.31 CA265_RS23475 aspartate kinase; homoserine dehydrogenase (EC 2.7.2.4; EC 1.1.1.3) (from data) 0.94 6
Mucilaginibacter yixingensis YX-36 DSM 26809 0.42 ABZR88_RS11600 3-isopropylmalate dehydratase small subunit 0.32 ABZR88_RS18950 bifunctional aspartate kinase/homoserine dehydrogenase I — —
Bacteroides stercoris CC31F 0.42 HMPREF1181_RS14140 3-isopropylmalate dehydratase small subunit 0.27 HMPREF1181_RS00060 bifunctional aspartate kinase/homoserine dehydrogenase I 0.88 11
Phocaeicola dorei CL03T12C01 0.40 ABI39_RS10205 3-isopropylmalate dehydratase small subunit 0.31 ABI39_RS10430 bifunctional aspartate kinase/homoserine dehydrogenase I 0.84 7
Phocaeicola vulgatus CL09T03C04 0.40 HMPREF1058_RS14555 3-isopropylmalate dehydratase small subunit 0.31 HMPREF1058_RS14720 bifunctional aspartate kinase/homoserine dehydrogenase I 0.80 15
Parabacteroides merdae CL09T00C40 0.39 HMPREF1078_RS16655 3-isopropylmalate dehydratase small subunit 0.31 HMPREF1078_RS10385 bifunctional aspartate kinase/homoserine dehydrogenase I 0.84 45
Lysobacter sp. OAE881 0.39 ABIE51_RS17580 3-isopropylmalate dehydratase small subunit 0.31 ABIE51_RS17520 bifunctional aspartate kinase/homoserine dehydrogenase I 0.90 17
Echinicola vietnamensis KMM 6221, DSM 17526 0.38 Echvi_2060 3-isopropylmalate dehydratase, small subunit 0.34 Echvi_2000 aspartate kinase / homoserine dehydrogenase (EC 2.7.2.4; EC 1.1.1.3) (from data) — —
Bacteroides ovatus ATCC 8483 0.38 BACOVA_04602 3-isopropylmalate dehydratase, small subunit 0.27 BACOVA_03021 homoserine dehydrogenase 0.95 8
Bacteroides thetaiotaomicron VPI-5482 0.37 BT1859 3-isopropylmalate dehydratase small subunit (NCBI ptt file) 0.28 BT2403 aspartate kinase / homoserine dehydrogenase (EC 2.7.2.4; EC 1.1.1.3) (from data) 0.90 1

Not shown: 56 genomes with orthologs for OKFHMN_10730 only; 0 genomes with orthologs for OKFHMN_11110 only