Conservation of cofitness between NOLOHH_15540 and NOLOHH_17355 in Escherichia coli ECOR27

41 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Escherichia coli ECOR27 1.0 NOLOHH_15540 mdtB multidrug efflux RND transporter permease subunit MdtB 1.0 NOLOHH_17355 gdhA NADP-specific glutamate dehydrogenase 0.62 4
Escherichia coli ECRC98 1.00 JDDGAC_28305 mdtB multidrug efflux RND transporter permease subunit MdtB 1.00 JDDGAC_01415 gdhA NADP-specific glutamate dehydrogenase low > 86
Escherichia coli ECRC100 1.00 OKFHMN_24195 mdtB multidrug efflux RND transporter permease subunit MdtB 1.00 OKFHMN_26840 gdhA NADP-specific glutamate dehydrogenase low > 80
Escherichia coli ECRC102 1.00 NIAGMN_22140 mdtB multidrug efflux RND transporter permease subunit MdtB 1.00 NIAGMN_01225 gdhA NADP-specific glutamate dehydrogenase — —
Escherichia coli ECRC101 1.00 MCAODC_20745 mdtB multidrug efflux RND transporter permease subunit MdtB 1.00 MCAODC_18570 gdhA NADP-specific glutamate dehydrogenase low > 87
Escherichia coli ECRC99 1.00 KEDOAH_03955 mdtB multidrug efflux RND transporter permease subunit MdtB 1.00 KEDOAH_01270 gdhA NADP-specific glutamate dehydrogenase — —
Escherichia coli Nissle 1917 1.00 ECOLIN_RS12200 multidrug efflux RND transporter permease subunit MdtB 1.00 ECOLIN_RS09810 NADP-specific glutamate dehydrogenase — —
Escherichia coli BW25113 1.00 b2075 mdtB multidrug efflux system, subunit B (NCBI) 1.00 b1761 gdhA glutamate dehydrogenase (NCBI) low > 76
Escherichia fergusonii Becca 1.00 EFB2_01780 Multidrug resistance protein MdtB 1.00 EFB2_02232 NADP-specific glutamate dehydrogenase low > 86
Escherichia coli BL21 1.00 ECD_01980 multidrug efflux system, subunit B 1.00 ECD_01730 glutamate dehydrogenase, NADP-specific — —
Escherichia coli HS(pFamp)R (ATCC 700891) 1.00 OHPLBJKB_01629 Multidrug resistance protein MdtB 1.00 OHPLBJKB_01971 NADP-specific glutamate dehydrogenase low > 73
Escherichia coli ECRC62 1.00 BNILDI_14455 mdtB multidrug efflux RND transporter permease subunit MdtB 1.00 BNILDI_16140 gdhA NADP-specific glutamate dehydrogenase low > 75
Escherichia coli ECOR38 1.00 HEPCGN_02885 mdtB multidrug efflux RND transporter permease subunit MdtB 1.00 HEPCGN_05205 gdhA NADP-specific glutamate dehydrogenase low > 87
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.91 GFF3854 Multidrug transporter MdtB 0.94 GFF3487 NADP-specific glutamate dehydrogenase (EC 1.4.1.4) low > 78
Klebsiella michiganensis M5al 0.90 BWI76_RS19255 multidrug transporter subunit MdtB 0.92 BWI76_RS11610 glutamate dehydrogenase low > 92
Enterobacter sp. TBS_079 0.90 MPMX20_03061 Multidrug resistance protein MdtB 0.92 MPMX20_01854 NADP-specific glutamate dehydrogenase low > 85
Enterobacter asburiae PDN3 0.90 EX28DRAFT_0483 Cation/multidrug efflux pump 0.93 EX28DRAFT_1763 Glutamate dehydrogenase/leucine dehydrogenase low > 76
Serratia liquefaciens MT49 0.81 IAI46_18975 MdtB/MuxB family multidrug efflux RND transporter permease subunit 0.85 IAI46_24165 NADP-specific glutamate dehydrogenase low > 86
Pantoea sp. MT58 0.81 IAI47_06870 MdtB/MuxB family multidrug efflux RND transporter permease subunit 0.18 IAI47_20110 Glu/Leu/Phe/Val dehydrogenase low > 76
Erwinia tracheiphila SCR3 0.80 LU632_RS08690 MdtB/MuxB family multidrug efflux RND transporter permease subunit 0.19 LU632_RS12465 Glu/Leu/Phe/Val dehydrogenase low > 74
Pectobacterium carotovorum WPP14 0.79 HER17_RS06320 MdtB/MuxB family multidrug efflux RND transporter permease subunit 0.86 HER17_RS21320 NADP-specific glutamate dehydrogenase low > 75
Ralstonia solanacearum UW163 0.66 UW163_RS21010 multidrug transporter subunit MdtB 0.19 UW163_RS02035 Glu/Leu/Phe/Val dehydrogenase — —
Ralstonia solanacearum IBSBF1503 0.66 RALBFv3_RS18120 multidrug transporter subunit MdtB 0.19 RALBFv3_RS11550 Glu/Leu/Phe/Val dehydrogenase — —
Ralstonia solanacearum PSI07 0.65 RPSI07_RS05515 multidrug transporter subunit MdtB 0.19 RPSI07_RS21660 Glu/Leu/Phe/Val dehydrogenase low > 81
Ralstonia sp. UNC404CL21Col 0.65 ABZR87_RS19025 MdtB/MuxB family multidrug efflux RND transporter permease subunit 0.19 ABZR87_RS07515 Glu/Leu/Phe/Val dehydrogenase — —
Ralstonia solanacearum GMI1000 0.65 RS_RS22915 multidrug transporter subunit MdtB 0.19 RS_RS02380 Glu/Leu/Phe/Val dehydrogenase low > 80
Cupriavidus basilensis FW507-4G11 0.64 RR42_RS03310 multidrug transporter 0.69 RR42_RS33640 glutamate dehydrogenase low > 128
Rahnella sp. WP5 0.62 EX31_RS13380 MMPL family transporter 0.89 EX31_RS08255 NADP-specific glutamate dehydrogenase low > 89
Pseudomonas putida KT2440 0.62 PP_3584 multidrug efflux transport system - membrane subunit 0.67 PP_0675 glutamate dehydrogenase, NADP-dependent low > 96
Pseudomonas fluorescens GW456-L13 0.62 PfGW456L13_3266 Acriflavin resistance plasma membrane protein 0.67 PfGW456L13_1455 NADP-specific glutamate dehydrogenase (EC 1.4.1.4) low > 87
Pseudomonas fluorescens SBW25-INTG 0.61 PFLU_RS13430 MdtB/MuxB family multidrug efflux RND transporter permease subunit 0.67 PFLU_RS26175 NADP-specific glutamate dehydrogenase low > 109
Pseudomonas fluorescens SBW25 0.61 PFLU_RS13430 MdtB/MuxB family multidrug efflux RND transporter permease subunit 0.67 PFLU_RS26175 NADP-specific glutamate dehydrogenase low > 109
Pseudomonas simiae WCS417 0.61 PS417_12745 multidrug transporter 0.68 PS417_24260 glutamate dehydrogenase low > 88
Acidovorax sp. GW101-3H11 0.59 Ac3H11_3618 Cobalt-zinc-cadmium resistance protein CzcA; Cation efflux system protein CusA 0.71 Ac3H11_315 NADP-specific glutamate dehydrogenase (EC 1.4.1.4) low > 79
Pseudomonas stutzeri RCH2 0.59 Psest_2139 Cation/multidrug efflux pump 0.66 Psest_3438 Glutamate dehydrogenase/leucine dehydrogenase low > 67
Burkholderia phytofirmans PsJN 0.58 BPHYT_RS07785 multidrug transporter 0.19 BPHYT_RS16705 glutamate dehydrogenase — —
Castellaniella sp019104865 MT123 0.57 ABCV34_RS14620 multidrug efflux RND transporter permease subunit 0.72 ABCV34_RS06190 NADP-specific glutamate dehydrogenase low > 48
Variovorax sp. SCN45 0.56 GFF6659 Multidrug efflux system MdtABC-TolC, inner-membrane proton/drug antiporter MdtB (RND type) 0.71 GFF3009 NADP-specific glutamate dehydrogenase (EC 1.4.1.4) low > 127
Hydrogenophaga sp. GW460-11-11-14-LB1 0.55 GFF487 Cobalt-zinc-cadmium resistance protein CzcA; Cation efflux system protein CusA 0.72 GFF5486 NADP-specific glutamate dehydrogenase (EC 1.4.1.4) low > 90
Variovorax sp. OAS795 0.53 ABID97_RS20855 efflux RND transporter permease subunit 0.20 ABID97_RS00235 Glu/Leu/Phe/Val dehydrogenase low > 91
Bacteroides thetaiotaomicron VPI-5482 0.25 BT2252 multidrug efflux membrane fusion protein (NCBI ptt file) 0.59 BT1970 glutamate dehydrogenase (NCBI ptt file) low > 81
Parabacteroides merdae CL09T00C40 0.24 HMPREF1078_RS05470 efflux RND transporter permease subunit 0.58 HMPREF1078_RS13375 NADP-specific glutamate dehydrogenase 0.56 2

Not shown: 25 genomes with orthologs for NOLOHH_15540 only; 11 genomes with orthologs for NOLOHH_17355 only