Conservation of cofitness between NOLOHH_16910 and NOLOHH_03195 in Escherichia coli ECOR27

44 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Escherichia coli ECOR27 1.0 NOLOHH_16910 yobA CopC domain-containing protein YobA 1.0 NOLOHH_03195 Dihydrofolate reductase 0.70 1
Escherichia coli BW25113 1.00 b1841 yobA hypothetical protein (NCBI) 0.82 b0048 folA dihydrofolate reductase (NCBI) — —
Escherichia coli HS(pFamp)R (ATCC 700891) 1.00 OHPLBJKB_01890 Protein YobA 1.00 OHPLBJKB_03608 Dihydrofolate reductase low > 73
Escherichia coli Nissle 1917 1.00 ECOLIN_RS10250 CopC domain-containing protein YobA 0.82 ECOLIN_RS00260 type 3 dihydrofolate reductase — —
Escherichia fergusonii Becca 1.00 EFB2_02103 Protein YobA 1.00 EFB2_03997 Dihydrofolate reductase low > 86
Escherichia coli BL21 1.00 ECD_01812 CopC family protein 0.82 ECD_00052 dihydrofolate reductase — —
Escherichia coli ECRC62 1.00 BNILDI_15705 yobA CopC domain-containing protein YobA 1.00 BNILDI_08410 Dihydrofolate reductase low > 75
Escherichia coli ECRC102 0.99 NIAGMN_01660 yobA CopC domain-containing protein YobA 0.99 NIAGMN_08710 Dihydrofolate reductase — —
Escherichia coli ECRC99 0.99 KEDOAH_01705 yobA CopC domain-containing protein YobA 0.99 KEDOAH_17295 Dihydrofolate reductase — —
Escherichia coli ECRC100 0.99 OKFHMN_26400 yobA CopC domain-containing protein YobA 0.99 OKFHMN_10860 Dihydrofolate reductase low > 80
Escherichia coli ECRC98 0.99 JDDGAC_00975 yobA CopC domain-containing protein YobA 0.99 JDDGAC_14455 Dihydrofolate reductase low > 86
Escherichia coli ECRC101 0.99 MCAODC_19005 yobA CopC domain-containing protein YobA 0.99 MCAODC_01375 Dihydrofolate reductase low > 87
Escherichia coli ECOR38 0.98 HEPCGN_04800 yobA CopC domain-containing protein YobA 1.00 HEPCGN_08850 Dihydrofolate reductase low > 87
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.70 GFF1620 Copper resistance protein CopC 0.80 GFF193 Dihydrofolate reductase (EC 1.5.1.3) — —
Enterobacter asburiae PDN3 0.56 EX28DRAFT_0713 Uncharacterized protein, homolog of Cu resistance protein CopC 0.77 EX28DRAFT_3642 Dihydrofolate reductase — —
Enterobacter sp. TBS_079 0.52 MPMX20_02748 Protein YobA 0.77 MPMX20_00744 IS1595 family transposase ISSsu9 — —
Klebsiella michiganensis M5al 0.52 BWI76_RS18060 hypothetical protein 0.78 BWI76_RS04505 dihydrofolate reductase — —
Serratia liquefaciens MT49 0.45 IAI46_10005 CopC domain-containing protein YobA 0.68 IAI46_03225 type 3 dihydrofolate reductase — —
Erwinia tracheiphila SCR3 0.45 LU632_RS13300 yobA CopC domain-containing protein YobA 0.62 LU632_RS02745 folA type 3 dihydrofolate reductase — —
Rahnella sp. WP5 0.40 EX31_RS24770 copper homeostasis periplasmic binding protein CopC 0.69 EX31_RS03795 type 3 dihydrofolate reductase — —
Dickeya dadantii 3937 0.33 DDA3937_RS10160 copper homeostasis periplasmic binding protein CopC 0.66 DDA3937_RS18285 type 3 dihydrofolate reductase — —
Dickeya dianthicola ME23 0.33 DZA65_RS10605 copper homeostasis periplasmic binding protein CopC 0.62 DZA65_RS19360 type 3 dihydrofolate reductase — —
Dickeya dianthicola 67-19 0.32 HGI48_RS10190 copper homeostasis periplasmic binding protein CopC 0.65 HGI48_RS18220 type 3 dihydrofolate reductase — —
Rhizobium sp. OAE497 0.32 ABIE40_RS22750 copper homeostasis periplasmic binding protein CopC 0.22 ABIE40_RS11540 dihydrofolate reductase — —
Pseudomonas fluorescens FW300-N2E3 0.31 AO353_26590 hypothetical protein 0.33 AO353_08370 diacylglycerol kinase — —
Pseudomonas simiae WCS417 0.30 PS417_17345 hypothetical protein 0.34 PS417_26905 diacylglycerol kinase — —
Burkholderia phytofirmans PsJN 0.30 BPHYT_RS16425 copper resistance protein 0.35 BPHYT_RS14700 diacylglycerol kinase — —
Pseudomonas fluorescens SBW25 0.30 PFLU_RS19270 copper homeostasis periplasmic binding protein CopC 0.33 PFLU_RS28565 dihydrofolate reductase — —
Pseudomonas fluorescens SBW25-INTG 0.30 PFLU_RS19270 copper homeostasis periplasmic binding protein CopC 0.33 PFLU_RS28565 dihydrofolate reductase — —
Paraburkholderia sabiae LMG 24235 0.29 QEN71_RS02285 copper homeostasis periplasmic binding protein CopC 0.31 QEN71_RS04275 dihydrofolate reductase — —
Paraburkholderia graminis OAS925 0.26 ABIE53_005709 methionine-rich copper-binding protein CopC 0.34 ABIE53_003115 dihydrofolate reductase — —
Pseudomonas syringae pv. syringae B728a 0.25 Psyr_1495 Copper resistance protein CopC 0.34 Psyr_4737 dihydrofolate reductase — —
Ralstonia solanacearum PSI07 0.25 RPSI07_RS02370 copper resistance protein C 0.36 RPSI07_RS19500 dihydrofolate reductase — —
Pseudomonas syringae pv. syringae B728a ΔmexB 0.25 Psyr_1495 Copper resistance protein CopC 0.34 Psyr_4737 dihydrofolate reductase — —
Pseudomonas fluorescens GW456-L13 0.24 PfGW456L13_3976 Copper resistance protein C precursor 0.33 PfGW456L13_969 Dihydrofolate reductase (EC 1.5.1.3) — —
Pseudomonas fluorescens FW300-N1B4 0.23 Pf1N1B4_46 Copper resistance protein C precursor 0.33 Pf1N1B4_2300 Dihydrofolate reductase (EC 1.5.1.3) — —
Cupriavidus basilensis FW507-4G11 0.23 RR42_RS35360 copper resistance protein CopC 0.35 RR42_RS14745 diacylglycerol kinase — —
Magnetospirillum magneticum AMB-1 0.22 AMB_RS01165 hypothetical protein 0.32 AMB_RS06740 dihydrofolate reductase — —
Ralstonia solanacearum GMI1000 0.22 RS_RS20270 copper resistance protein C 0.35 RS_RS04705 dihydrofolate reductase — —
Ralstonia solanacearum UW163 0.21 UW163_RS22010 copper resistance protein C 0.34 UW163_RS15840 dihydrofolate reductase — —
Ralstonia solanacearum IBSBF1503 0.21 RALBFv3_RS20875 copper resistance protein C 0.34 RALBFv3_RS13970 dihydrofolate reductase — —
Brevundimonas sp. GW460-12-10-14-LB2 0.21 A4249_RS03230 copper homeostasis periplasmic binding protein CopC 0.31 A4249_RS05050 dihydrofolate reductase — —
Ralstonia sp. UNC404CL21Col 0.21 ABZR87_RS21865 copper homeostasis periplasmic binding protein CopC 0.34 ABZR87_RS09665 dihydrofolate reductase — —
Pseudomonas fluorescens FW300-N2E2 0.20 Pf6N2E2_5550 Copper resistance protein C precursor 0.35 Pf6N2E2_4561 Dihydrofolate reductase (EC 1.5.1.3) — —
Pseudomonas fluorescens FW300-N2C3 0.20 AO356_18130 copper resistance protein CopC 0.34 AO356_13235 diacylglycerol kinase — —

Not shown: 2 genomes with orthologs for NOLOHH_16910 only; 31 genomes with orthologs for NOLOHH_03195 only