Conservation of cofitness between HER17_RS01300 and HER17_RS16185 in Pectobacterium carotovorum WPP14

43 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Pectobacterium carotovorum WPP14 1.0 HER17_RS01300 protoheme IX biogenesis protein HemY 1.0 HER17_RS16185 lytic murein transglycosylase B 0.71 20
Serratia liquefaciens MT49 0.79 IAI46_00680 protoheme IX biogenesis protein HemY 0.78 IAI46_18155 lytic murein transglycosylase B low > 86
Dickeya dadantii 3937 0.76 DDA3937_RS19935 protoheme IX biogenesis protein HemY 0.70 DDA3937_RS03745 lytic murein transglycosylase B low > 74
Rahnella sp. WP5 0.75 EX31_RS15130 protoheme IX biogenesis protein HemY 0.75 EX31_RS07810 lytic murein transglycosylase B 0.46 12
Dickeya dianthicola 67-19 0.74 HGI48_RS20090 protoheme IX biogenesis protein HemY 0.70 HGI48_RS03780 lytic murein transglycosylase B low > 71
Dickeya dianthicola ME23 0.74 DZA65_RS21135 protoheme IX biogenesis protein HemY 0.70 DZA65_RS03910 lytic murein transglycosylase B low > 75
Erwinia tracheiphila SCR3 0.73 LU632_RS24175 hemY protoheme IX biogenesis protein HemY 0.67 LU632_RS15745 mltB lytic murein transglycosylase B low > 74
Escherichia coli ECRC98 0.73 JDDGAC_18090 hemY protoheme IX biogenesis protein HemY 0.74 JDDGAC_24360 mltB lytic murein transglycosylase B low > 86
Escherichia coli ECRC100 0.73 OKFHMN_14465 hemY protoheme IX biogenesis protein HemY 0.74 OKFHMN_20695 mltB lytic murein transglycosylase B low > 80
Escherichia coli HS(pFamp)R (ATCC 700891) 0.73 OHPLBJKB_04251 Protein HemY 0.75 OHPLBJKB_01033 Membrane-bound lytic murein transglycosylase B low > 73
Escherichia coli ECOR38 0.73 HEPCGN_13185 hemY protoheme IX biogenesis protein HemY 0.74 HEPCGN_19890 mltB lytic murein transglycosylase B low > 87
Escherichia coli ECOR27 0.73 NOLOHH_06610 hemY protoheme IX biogenesis protein HemY 0.74 NOLOHH_12535 mltB lytic murein transglycosylase B low > 75
Escherichia coli ECRC102 0.73 NIAGMN_12220 hemY protoheme IX biogenesis protein HemY 0.74 NIAGMN_18465 mltB lytic murein transglycosylase B
Escherichia coli Nissle 1917 0.73 ECOLIN_RS21820 protoheme IX biogenesis protein HemY 0.74 ECOLIN_RS15070 lytic murein transglycosylase B
Escherichia coli ECRC99 0.73 KEDOAH_13685 hemY protoheme IX biogenesis protein HemY 0.74 KEDOAH_07440 mltB lytic murein transglycosylase B
Escherichia coli ECRC62 0.73 BNILDI_04925 hemY protoheme IX biogenesis protein HemY 0.74 BNILDI_11095 mltB lytic murein transglycosylase B low > 75
Escherichia coli BW25113 0.73 b3802 hemY predicted protoheme IX synthesis protein (NCBI) 0.76 b2701 mltB membrane-bound lytic murein transglycosylase B (NCBI) low > 76
Escherichia fergusonii Becca 0.73 EFB2_04836 Protein HemY 0.74 EFB2_01223 Membrane-bound lytic murein transglycosylase B low > 86
Escherichia coli BL21 0.73 ECD_03677 putative protoheme IX synthesis protein 0.74 ECD_02551 membrane-bound lytic murein transglycosylase B low > 61
Escherichia coli ECRC101 0.73 MCAODC_04970 hemY protoheme IX biogenesis protein HemY 0.74 MCAODC_11220 mltB lytic murein transglycosylase B low > 87
Enterobacter sp. TBS_079 0.71 MPMX20_04473 Protein HemY 0.74 MPMX20_03585 Membrane-bound lytic murein transglycosylase B low > 85
Enterobacter asburiae PDN3 0.71 EX28DRAFT_4471 heme biosynthesis-associated TPR protein 0.73 EX28DRAFT_2790 lytic murein transglycosylase B low > 76
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.69 GFF226 Uncharacterized protein EC-HemY, likely associated with heme metabolism based on gene clustering with hemC, hemD in Proteobacteria (unrelated to HemY-type PPO in GramPositives) 0.77 GFF4695 Membrane-bound lytic murein transglycosylase B precursor (EC 3.2.1.-) low > 78
Klebsiella michiganensis M5al 0.69 BWI76_RS01165 protoheme IX biogenesis protein HemY 0.74 BWI76_RS22210 murein transglycosylase B low > 92
Pantoea sp. MT58 0.68 IAI47_18440 protoheme IX biogenesis protein HemY 0.72 IAI47_04275 lytic murein transglycosylase B low > 76
Kangiella aquimarina DSM 16071 0.18 B158DRAFT_0255 Uncharacterized enzyme of heme biosynthesis 0.33 B158DRAFT_0081 lytic murein transglycosylase B low > 40
Pseudomonas stutzeri RCH2 0.16 Psest_3745 Uncharacterized enzyme of heme biosynthesis 0.36 Psest_0514 lytic murein transglycosylase B 0.26 24
Pseudomonas fluorescens FW300-N2E2 0.15 Pf6N2E2_4433 Uncharacterized protein EC-HemY, likely associated with heme metabolism based on gene clustering with hemC, hemD in Proteobacteria (unrelated to HemY-type PPO in GramPositives) 0.37 Pf6N2E2_4999 Membrane-bound lytic murein transglycosylase B precursor (EC 3.2.1.-) low > 103
Pseudomonas fluorescens FW300-N2C3 0.14 AO356_12800 heme biosynthesis protein HemY 0.38 AO356_15320 lytic transglycosylase low > 104
Pseudomonas fluorescens GW456-L13 0.13 PfGW456L13_859 Uncharacterized protein EC-HemY, likely associated with heme metabolism based on gene clustering with hemC, hemD in Proteobacteria (unrelated to HemY-type PPO in GramPositives) 0.38 PfGW456L13_1362 Membrane-bound lytic murein transglycosylase B precursor (EC 3.2.1.-) low > 87
Pseudomonas fluorescens FW300-N2E3 0.13 AO353_08975 heme biosynthesis protein HemY 0.38 AO353_06465 lytic transglycosylase low > 101
Pseudomonas simiae WCS417 0.13 PS417_27515 heme biosynthesis protein HemY 0.38 PS417_24715 lytic transglycosylase low > 88
Pseudomonas fluorescens FW300-N1B4 0.13 Pf1N1B4_2188 Uncharacterized protein EC-HemY, likely associated with heme metabolism based on gene clustering with hemC, hemD in Proteobacteria (unrelated to HemY-type PPO in GramPositives) 0.38 Pf1N1B4_2694 Membrane-bound lytic murein transglycosylase B precursor (EC 3.2.1.-)
Pseudomonas fluorescens SBW25 0.12 PFLU_RS29195 heme biosynthesis protein HemY 0.38 PFLU_RS26645 lytic murein transglycosylase B low > 109
Shewanella sp. ANA-3 0.12 Shewana3_0383 HemY domain-containing protein (RefSeq) 0.27 Shewana3_0993 lytic murein transglycosylase B (RefSeq) low > 73
Shewanella loihica PV-4 0.12 Shew_0315 HemY domain-containing protein (RefSeq) 0.27 Shew_2937 lytic murein transglycosylase B (RefSeq)
Pseudomonas fluorescens SBW25-INTG 0.12 PFLU_RS29195 heme biosynthesis protein HemY 0.38 PFLU_RS26645 lytic murein transglycosylase B low > 109
Pseudomonas sp. RS175 0.12 PFR28_04363 Protein HemY 0.38 PFR28_03866 Membrane-bound lytic murein transglycosylase B low > 88
Pseudomonas putida KT2440 0.12 PP_0189 putative heme biosynthesis protein 0.36 PP_4805 membrane-bound lytic murein transglycosylase B 0.11 82
Pseudomonas sp. S08-1 0.12 OH686_13915 Uncharacterized protein EC-HemY in Proteobacteria (unrelated to HemY-type PPO in GramPositives) 0.37 OH686_09310 lytic murein transglycosylase B low > 80
Pseudomonas syringae pv. syringae B728a ΔmexB 0.12 Psyr_0059 HemY, N-terminal:HemY, N-terminal:HemY, N-terminal 0.38 Psyr_4363 membrane-bound lytic murein transglycosylase B low > 86
Shewanella amazonensis SB2B 0.12 Sama_3257 HemY protein (RefSeq) 0.28 Sama_2590 lytic murein transglycosylase B (RefSeq) low > 62
Pseudomonas syringae pv. syringae B728a 0.12 Psyr_0059 HemY, N-terminal:HemY, N-terminal:HemY, N-terminal 0.38 Psyr_4363 membrane-bound lytic murein transglycosylase B low > 86
Herbaspirillum seropedicae SmR1 0.08 HSERO_RS14650 porphyrin biosynthesis protein 0.35 HSERO_RS04945 murein transglycosylase

Not shown: 3 genomes with orthologs for HER17_RS01300 only; 21 genomes with orthologs for HER17_RS16185 only