Conservation of cofitness between ECD_01634 and ECD_00941 in Escherichia coli BL21

42 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Escherichia coli BL21 1.0 ECD_01634 multidrug efflux system transporter 1.0 ECD_00941 NAD(P)H-dependent FMN reductase 0.56 18
Escherichia coli HS(pFamp)R (ATCC 700891) 1.00 OHPLBJKB_02061 Multidrug resistance protein MdtK 1.00 OHPLBJKB_02729 FMN reductase (NADPH) low > 73
Escherichia coli BW25113 1.00 b1663 mdtK multidrug efflux protein NorM (NCBI) 1.00 b0937 ssuE NAD(P)H-dependent FMN reductase (NCBI) low > 76
Escherichia fergusonii Becca 1.00 EFB2_02329 Multidrug resistance protein MdtK 0.92 EFB2_03127 FMN reductase (NADPH) low > 86
Escherichia coli Nissle 1917 1.00 ECOLIN_RS09270 multidrug efflux MATE transporter MdtK 0.92 ECOLIN_RS04960 NADPH-dependent FMN reductase — —
Escherichia coli ECOR38 1.00 HEPCGN_05745 mdtK multidrug efflux MATE transporter MdtK 0.92 HEPCGN_23185 ssuE NADPH-dependent FMN reductase low > 85
Escherichia coli ECOR27 1.00 NOLOHH_17880 mdtK multidrug efflux MATE transporter MdtK 0.99 NOLOHH_21890 ssuE NADPH-dependent FMN reductase — —
Escherichia coli ECRC62 1.00 BNILDI_16670 mdtK multidrug efflux MATE transporter MdtK 1.00 BNILDI_20145 ssuE NADPH-dependent FMN reductase — —
Escherichia coli ECRC99 1.00 KEDOAH_00750 mdtK multidrug efflux MATE transporter MdtK 0.91 KEDOAH_22395 ssuE NADPH-dependent FMN reductase — —
Escherichia coli ECRC98 1.00 JDDGAC_01950 mdtK multidrug efflux MATE transporter MdtK 0.91 JDDGAC_08950 ssuE NADPH-dependent FMN reductase — —
Escherichia coli ECRC101 1.00 MCAODC_18050 mdtK multidrug efflux MATE transporter MdtK 0.91 MCAODC_24730 ssuE NADPH-dependent FMN reductase — —
Escherichia coli ECRC101 1.00 OKFHMN_27360 mdtK multidrug efflux MATE transporter MdtK 0.91 OKFHMN_05340 ssuE NADPH-dependent FMN reductase — —
Escherichia coli ECRC102 1.00 NIAGMN_00705 mdtK multidrug efflux MATE transporter MdtK 0.91 NIAGMN_03060 ssuE NADPH-dependent FMN reductase — —
Enterobacter sp. TBS_079 0.91 MPMX20_01973 Multidrug resistance protein MdtK 0.85 MPMX20_01595 FMN reductase (NADPH) low > 85
Klebsiella michiganensis M5al 0.89 BWI76_RS16535 MATE family efflux transporter 0.80 BWI76_RS09905 FMN reductase (NADPH) low > 92
Enterobacter asburiae PDN3 0.89 EX28DRAFT_1660 putative efflux protein, MATE family 0.86 EX28DRAFT_1999 FMN reductase, SsuE family low > 76
Serratia liquefaciens MT49 0.77 IAI46_11210 MATE family efflux transporter 0.58 IAI46_08800 NADPH-dependent FMN reductase low > 86
Pantoea sp. MT58 0.76 IAI47_10820 MATE family efflux transporter 0.60 IAI47_12720 NADPH-dependent FMN reductase low > 76
Dickeya dianthicola 67-19 0.73 HGI48_RS12700 MATE family efflux transporter 0.60 HGI48_RS12930 NADPH-dependent FMN reductase low > 71
Dickeya dianthicola ME23 0.73 DZA65_RS13155 MATE family efflux transporter 0.60 DZA65_RS13395 NADPH-dependent FMN reductase low > 75
Rahnella sp. WP5 0.72 EX31_RS13855 MATE family efflux transporter 0.52 EX31_RS18100 NADPH-dependent FMN reductase low > 89
Pseudomonas sp. S08-1 0.43 OH686_02075 Na(+)/drug antiporter, MATE family of MDR efflux pumps 0.44 OH686_11580 FMN reductase low > 80
Pseudomonas fluorescens GW456-L13 0.41 PfGW456L13_4049 Multi antimicrobial extrusion protein (Na(+)/drug antiporter), MATE family of MDR efflux pumps 0.47 PfGW456L13_918 FMN reductase (EC 1.5.1.29) low > 87
Pseudomonas fluorescens SBW25 0.41 PFLU_RS07610 MATE family efflux transporter 0.52 PFLU_RS28840 NADPH-dependent FMN reductase low > 109
Pseudomonas fluorescens FW300-N2E3 0.41 AO353_00550 MATE family efflux transporter 0.52 AO353_08670 NADPH-dependent FMN reductase low > 101
Pseudomonas fluorescens SBW25-INTG 0.41 PFLU_RS07610 MATE family efflux transporter 0.52 PFLU_RS28840 NADPH-dependent FMN reductase low > 109
Pseudomonas sp. RS175 0.41 PFR28_01102 Multidrug resistance protein NorM 0.52 PFR28_04305 FMN reductase (NADPH) low > 88
Pseudomonas fluorescens FW300-N1B4 0.41 Pf1N1B4_3892 Multi antimicrobial extrusion protein (Na(+)/drug antiporter), MATE family of MDR efflux pumps 0.51 Pf1N1B4_2247 FMN reductase (EC 1.5.1.29) low > 87
Pseudomonas simiae WCS417 0.41 PS417_07530 multidrug transporter 0.52 PS417_27175 NAD(P)H-dependent FMN reductase low > 88
Pseudomonas fluorescens FW300-N2C3 0.41 AO356_02370 MATE family efflux transporter 0.53 AO356_13100 NADPH-dependent FMN reductase low > 104
Pseudomonas fluorescens FW300-N2E2 0.41 Pf6N2E2_2298 Multi antimicrobial extrusion protein (Na(+)/drug antiporter), MATE family of MDR efflux pumps 0.53 Pf6N2E2_4502 FMN reductase (EC 1.5.1.29) low > 103
Pseudomonas stutzeri RCH2 0.40 Psest_2549 putative efflux protein, MATE family 0.46 Psest_4056 FMN reductase, SsuE family low > 67
Ralstonia sp. UNC404CL21Col 0.23 ABZR87_RS10730 MATE family efflux transporter 0.40 ABZR87_RS11495 NADPH-dependent FMN reductase low > 80
Cupriavidus basilensis FW507-4G11 0.22 RR42_RS13335 multidrug transporter MatE 0.18 RR42_RS30325 FMN reductase low > 128
Variovorax sp. OAS795 0.22 ABID97_RS14630 MATE family efflux transporter 0.35 ABID97_RS15470 NADPH-dependent FMN reductase low > 91
Ralstonia solanacearum GMI1000 0.21 RS_RS05915 MATE family efflux transporter 0.37 RS_RS06705 FMN reductase (NADPH) low > 80
Ralstonia solanacearum PSI07 0.21 RPSI07_RS18275 MATE family efflux transporter 0.37 RPSI07_RS17440 FMN reductase (NADPH) low > 81
Agrobacterium fabrum C58 0.20 Atu2172 multidrug efflux protein 0.20 Atu5527 NADH-dependent FMN reductase low > 89
Pseudomonas syringae pv. syringae B728a ΔmexB 0.19 Psyr_0073 Multi antimicrobial extrusion protein MatE 0.50 Psyr_3233 FMN reductase low > 86
Pseudomonas syringae pv. syringae B728a 0.19 Psyr_0073 Multi antimicrobial extrusion protein MatE 0.50 Psyr_3233 FMN reductase low > 86
Variovorax sp. SCN45 0.19 GFF1099 Na+-driven multidrug efflux pump 0.33 GFF1248 FMN reductase (NADPH) (EC 1.5.1.38) low > 127
Pseudomonas putida KT2440 0.19 PP_5262 Probable multidrug resistance protein NorM 0.51 PP_0236 NAD(P)H-dependent FMN reductase subunit low > 96
Acidovorax sp. GW101-3H11 0.17 Ac3H11_463 Multidrug and toxin extrusion (MATE) family efflux pump YdhE/NorM, homolog 0.35 Ac3H11_583 FMN reductase (EC 1.5.1.29) low > 79

Not shown: 50 genomes with orthologs for ECD_01634 only; 2 genomes with orthologs for ECD_00941 only