| Organism | Ratio1 | Gene1 | Name1 | Description1 | Ratio2 | Gene2 | Name2 | Description2 | Cofit | Rank |
| Vibrio cholerae E7946 ATCC 55056 | 1.0 | CSW01_12610 | | 3-isopropylmalate dehydratase small subunit | 1.0 | CSW01_16835 | | catabolite repressor/activator | 0.70 | 17 |
| Serratia liquefaciens MT49 | 0.78 | IAI46_03340 | | 3-isopropylmalate dehydratase small subunit | 0.42 | IAI46_03385 | | catabolite repressor/activator | low | > 86 |
| Dickeya dadantii 3937 | 0.78 | DDA3937_RS18130 | | 3-isopropylmalate dehydratase small subunit | 0.42 | DDA3937_RS18095 | | catabolite repressor/activator | low | > 74 |
| Pectobacterium carotovorum WPP14 | 0.77 | HER17_RS03070 | | 3-isopropylmalate dehydratase small subunit | 0.41 | HER17_RS03105 | | catabolite repressor/activator | low | > 75 |
| Dickeya dianthicola ME23 | 0.76 | DZA65_RS19215 | | 3-isopropylmalate dehydratase small subunit | 0.42 | DZA65_RS19175 | | catabolite repressor/activator | low | > 75 |
| Dickeya dianthicola 67-19 | 0.76 | HGI48_RS18070 | | 3-isopropylmalate dehydratase small subunit | 0.42 | HGI48_RS18030 | | catabolite repressor/activator | low | > 71 |
| Klebsiella pneumoniae MKP103 | 0.75 | KDGMDA_12895 | | 3-isopropylmalate dehydratase small subunit | 0.41 | KDGMDA_12935 | | catabolite repressor/activator | low | > 95 |
| Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 | 0.74 | GFF167 | | 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33) | 0.41 | GFF158 | | Fructose repressor FruR, LacI family | low | > 78 |
| Pantoea agglomerans CFBP13505 P0401 | 0.74 | PagCFBP13505_RS12985 | | 3-isopropylmalate dehydratase small subunit | 0.41 | PagCFBP13505_RS13020 | | catabolite repressor/activator | low | > 74 |
| Enterobacter asburiae PDN3 | 0.74 | EX28DRAFT_3667 | | 3-isopropylmalate dehydratase, small subunit | 0.42 | EX28DRAFT_3675 | | transcriptional regulator, LacI family | low | > 76 |
| Escherichia coli HS(pFamp)R (ATCC 700891) | 0.73 | OHPLBJKB_03586 | | 3-isopropylmalate dehydratase small subunit | 0.42 | OHPLBJKB_03579 | | Catabolite repressor/activator | low | > 74 |
| Klebsiella michiganensis M5al | 0.73 | BWI76_RS04665 | | 3-isopropylmalate dehydratase small subunit | 0.42 | BWI76_RS04705 | | DNA-binding transcriptional regulator FruR | low | > 92 |
| Pantoea sp. MT58 | 0.73 | IAI47_16015 | | 3-isopropylmalate dehydratase small subunit | 0.41 | IAI47_15980 | | catabolite repressor/activator | low | > 76 |
| Rahnella sp. WP5 | 0.73 | EX31_RS03695 | | 3-isopropylmalate dehydratase small subunit | 0.42 | EX31_RS03655 | | catabolite repressor/activator | low | > 89 |
| Escherichia coli ECRC62 | 0.72 | BNILDI_08535 | leuD | 3-isopropylmalate dehydratase small subunit | 0.41 | BNILDI_08580 | cra | catabolite repressor/activator | low | > 75 |
| Escherichia coli BW25113 | 0.72 | b0071 | leuD | isopropylmalate isomerase small subunit (NCBI) | 0.42 | b0080 | fruR | DNA-binding transcriptional dual regulator (NCBI) | low | > 76 |
| Escherichia coli BL21 | 0.72 | ECD_00073 | | 3-isopropylmalate dehydratase small subunit | 0.42 | ECD_00081 | | transcriptional repressor-activator for carbon metabolism | low | > 61 |
| Escherichia fergusonii Becca | 0.72 | EFB2_03974 | | 3-isopropylmalate dehydratase small subunit | 0.42 | EFB2_03967 | | Catabolite repressor/activator | low | > 86 |
| Escherichia coli ECOR27 | 0.72 | NOLOHH_03075 | leuD | 3-isopropylmalate dehydratase small subunit | 0.41 | NOLOHH_03030 | cra | catabolite repressor/activator | low | > 76 |
| Escherichia coli Nissle 1917 | 0.72 | ECOLIN_RS00385 | | 3-isopropylmalate dehydratase small subunit | 0.42 | ECOLIN_RS00430 | | catabolite repressor/activator | low | > 55 |
| Escherichia coli ECOR38 | 0.72 | HEPCGN_08710 | leuD | 3-isopropylmalate dehydratase small subunit | 0.41 | HEPCGN_08665 | cra | catabolite repressor/activator | low | > 88 |
| Escherichia coli ECRC102 | 0.72 | NIAGMN_08580 | leuD | 3-isopropylmalate dehydratase small subunit | 0.41 | NIAGMN_08535 | cra | catabolite repressor/activator | low | > 80 |
| Escherichia coli ECRC99 | 0.72 | KEDOAH_17425 | leuD | 3-isopropylmalate dehydratase small subunit | 0.41 | KEDOAH_17470 | cra | catabolite repressor/activator | — | — |
| Escherichia coli ECRC101 | 0.72 | MCAODC_01245 | leuD | 3-isopropylmalate dehydratase small subunit | 0.41 | MCAODC_01200 | cra | catabolite repressor/activator | low | > 88 |
| Escherichia coli ECRC98 | 0.72 | JDDGAC_14325 | leuD | 3-isopropylmalate dehydratase small subunit | 0.41 | JDDGAC_14280 | cra | catabolite repressor/activator | low | > 87 |
| Escherichia coli ECRC100 | 0.72 | OKFHMN_10730 | leuD | 3-isopropylmalate dehydratase small subunit | 0.41 | OKFHMN_10685 | cra | catabolite repressor/activator | low | > 79 |
| Enterobacter sp. TBS_079 | 0.71 | MPMX20_00766 | | 3-isopropylmalate dehydratase small subunit 1 | 0.42 | MPMX20_00773 | | Catabolite repressor/activator | low | > 85 |
| Erwinia tracheiphila SCR3 | 0.65 | LU632_RS02865 | leuD | 3-isopropylmalate dehydratase small subunit | 0.43 | LU632_RS02900 | cra | catabolite repressor/activator | low | > 74 |
| Erwinia tracheiphila HP pepo 2.2 | 0.65 | IJEDHG_06010 | leuD | 3-isopropylmalate dehydratase small subunit | 0.43 | IJEDHG_05975 | cra | catabolite repressor/activator | low | > 61 |
| Erwinia amylovora T8 | 0.64 | OLJFJH_01300 | | 3-isopropylmalate dehydratase small subunit | 0.40 | OLJFJH_01270 | | catabolite repressor/activator | low | > 58 |
| Pseudomonas simiae WCS417 | 0.61 | PS417_18595 | | 3-isopropylmalate dehydratase | 0.43 | PS417_03960 | | transcriptional regulator | — | — |
| Pseudomonas stutzeri RCH2 | 0.61 | Psest_2590 | | 3-isopropylmalate dehydratase, small subunit | 0.45 | Psest_3356 | | D-fructose-responsive transcription factor | low | > 67 |
| Pseudomonas sp. SVBP6 | 0.60 | COO64_RS05660 | leuD | 3-isopropylmalate dehydratase small subunit | 0.45 | COO64_RS11270 | cra | catabolite repressor/activator | low | > 93 |
| Pseudomonas fluorescens SBW25 | 0.60 | PFLU_RS20575 | | 3-isopropylmalate dehydratase small subunit | 0.43 | PFLU_RS04005 | | catabolite repressor/activator | low | > 109 |
| Pseudomonas fluorescens SBW25-INTG | 0.60 | PFLU_RS20575 | | 3-isopropylmalate dehydratase small subunit | 0.43 | PFLU_RS04005 | | catabolite repressor/activator | low | > 109 |
| Pseudomonas putida KT2440 | 0.60 | PP_1986 | | 3-isopropylmalate dehydratase small subunit | 0.41 | PP_0792 | | catabolite repressor-activator, DNA-binding transcriptional dual regulator | low | > 96 |
| Pseudomonas lactucae CFBP13502 | 0.60 | GEMAOFIL_03947 | | 3-isopropylmalate dehydratase small subunit | 0.39 | GEMAOFIL_00996 | | Catabolite repressor/activator | low | > 93 |
| Pseudomonas sp. BP01 | 0.60 | JOY50_RS16625 | leuD | 3-isopropylmalate dehydratase small subunit | 0.41 | JOY50_RS19320 | cra | catabolite repressor/activator | low | > 84 |
| Pseudomonas fluorescens FW300-N1B4 | 0.59 | Pf1N1B4_14 | | 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33) | 0.45 | Pf1N1B4_1147 | | Fructose repressor FruR, LacI family | — | — |
| Pseudomonas sp. DMC3 | 0.59 | GFF786 | | 3-isopropylmalate dehydratase small subunit 1 | 0.44 | GFF5002 | | Catabolite repressor/activator | low | > 89 |
| Pseudomonas aeruginosa PA14 | 0.59 | IKLFDK_15875 | | 3-isopropylmalate dehydratase small subunit | 0.44 | IKLFDK_18185 | | catabolite repressor/activator | low | > 100 |
| Pseudomonas fluorescens GW456-L13 | 0.59 | PfGW456L13_3947 | | 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33) | 0.42 | PfGW456L13_5077 | | Fructose repressor FruR, LacI family | low | > 87 |
| Pseudomonas sp. RS175 | 0.59 | PFR28_02823 | | 3-isopropylmalate dehydratase small subunit 1 | 0.45 | PFR28_00104 | | Catabolite repressor/activator | low | > 88 |
| Pseudomonas fluorescens FW300-N2E2 | 0.59 | Pf6N2E2_64 | | 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33) | 0.45 | Pf6N2E2_3340 | | Fructose repressor FruR, LacI family | 0.38 | 85 |
| Pseudomonas fluorescens FW300-N2E3 | 0.59 | AO353_20625 | | 3-isopropylmalate dehydratase | 0.45 | AO353_05490 | | transcriptional regulator | low | > 101 |
| Pseudomonas fluorescens FW300-N2C3 | 0.58 | AO356_21405 | | 3-isopropylmalate dehydratase | 0.45 | AO356_07340 | | transcriptional regulator | low | > 104 |
| Pseudomonas syringae pv. syringae B728a ΔmexB | 0.57 | Psyr_1984 | | 3-isopropylmalate dehydratase, small subunit | 0.46 | Psyr_0820 | | transcriptional regulator, LacI family | low | > 86 |
| Pseudomonas syringae pv. syringae B728a | 0.57 | Psyr_1984 | | 3-isopropylmalate dehydratase, small subunit | 0.46 | Psyr_0820 | | transcriptional regulator, LacI family | low | > 86 |
| Agrobacterium fabrum C58 | 0.49 | Atu2790 | | 3-isopropylmalate dehydratase, small subunit | 0.14 | Atu4743 | | LacI family transcriptional regulator | low | > 89 |
Not shown: 66 genomes with orthologs for CSW01_12610 only; 0 genomes with orthologs for CSW01_16835 only