Conservation of cofitness between CSW01_02455 and CSW01_10020 in Vibrio cholerae E7946 ATCC 55056

45 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Vibrio cholerae E7946 ATCC 55056 1.0 CSW01_02455 YggS family pyridoxal phosphate enzyme 1.0 CSW01_10020 ROK family protein 0.80 19
Dickeya dadantii 3937 0.62 DDA3937_RS17300 YggS family pyridoxal phosphate-dependent enzyme 0.50 DDA3937_RS10675 ROK family transcriptional regulator low > 74
Dickeya dianthicola 67-19 0.61 HGI48_RS17345 YggS family pyridoxal phosphate-dependent enzyme 0.49 HGI48_RS10675 ROK family transcriptional regulator low > 71
Dickeya dianthicola ME23 0.61 DZA65_RS18435 YggS family pyridoxal phosphate-dependent enzyme 0.49 DZA65_RS11145 ROK family transcriptional regulator low > 75
Pectobacterium carotovorum WPP14 0.61 HER17_RS03810 YggS family pyridoxal phosphate-dependent enzyme 0.50 HER17_RS10735 ROK family transcriptional regulator low > 75
Klebsiella michiganensis M5al 0.60 BWI76_RS24100 YggS family pyridoxal phosphate enzyme 0.47 BWI76_RS15955 transcriptional regulator low > 92
Enterobacter asburiae PDN3 0.59 EX28DRAFT_2989 pyridoxal phosphate enzyme, YggS family 0.48 EX28DRAFT_1493 Transcriptional regulator/sugar kinase low > 76
Pantoea agglomerans CFBP13505 P0401 0.59 PagCFBP13505_RS16100 YggS family pyridoxal phosphate-dependent enzyme 0.45 PagCFBP13505_RS06405 ROK family transcriptional regulator low > 74
Pantoea sp. MT58 0.58 IAI47_03595 YggS family pyridoxal phosphate-dependent enzyme 0.45 IAI47_09750 ROK family transcriptional regulator low > 76
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.58 GFF3054 Hypothetical protein YggS, proline synthase co-transcribed bacterial homolog PROSC 0.47 GFF1785 Mlc, transcriptional repressor of MalT (the transcriptional activator of maltose regulon) and manXYZ operon low > 78
Escherichia coli BL21 0.58 ECD_02781 UPF0001 family protein, PLP-binding 0.46 ECD_01563 glucosamine anaerobic growth regulon transcriptional repressor; autorepressor — —
Escherichia coli ECOR27 0.58 NOLOHH_11125 yggS pyridoxal phosphate homeostasis protein 0.47 NOLOHH_18245 mlc DNA-binding transcriptional repressor Mlc low > 76
Escherichia coli BW25113 0.58 b2951 yggS predicted enzyme (NCBI) 0.46 b1594 dgsA DNA-binding transcriptional repressor (NCBI) low > 76
Escherichia coli ECRC98 0.58 JDDGAC_22885 yggS pyridoxal phosphate homeostasis protein 0.47 JDDGAC_02330 mlc DNA-binding transcriptional repressor Mlc low > 87
Escherichia coli ECRC99 0.58 KEDOAH_08885 yggS pyridoxal phosphate homeostasis protein 0.47 KEDOAH_00365 mlc DNA-binding transcriptional repressor Mlc — —
Escherichia coli HS(pFamp)R (ATCC 700891) 0.58 OHPLBJKB_00765 Pyridoxal phosphate homeostasis protein 0.46 OHPLBJKB_02132 Protein mlc low > 74
Escherichia fergusonii Becca 0.58 EFB2_00951 Pyridoxal phosphate homeostasis protein 0.47 EFB2_02398 Protein mlc low > 86
Escherichia coli ECRC101 0.58 MCAODC_09775 yggS pyridoxal phosphate homeostasis protein 0.47 MCAODC_17670 mlc DNA-binding transcriptional repressor Mlc low > 87
Escherichia coli ECOR38 0.58 HEPCGN_18560 yggS pyridoxal phosphate homeostasis protein 0.47 HEPCGN_06115 mlc DNA-binding transcriptional repressor Mlc low > 88
Escherichia coli ECRC62 0.58 BNILDI_09705 yggS pyridoxal phosphate homeostasis protein 0.47 BNILDI_17035 mlc DNA-binding transcriptional repressor Mlc low > 75
Escherichia coli ECRC102 0.58 NIAGMN_17020 yggS pyridoxal phosphate homeostasis protein 0.47 NIAGMN_00335 mlc DNA-binding transcriptional repressor Mlc low > 80
Escherichia coli Nissle 1917 0.58 ECOLIN_RS16415 pyridoxal phosphate homeostasis protein 0.47 ECOLIN_RS08905 sugar metabolism global transcriptional regulator Mlc — —
Escherichia coli ECRC100 0.58 OKFHMN_19255 yggS pyridoxal phosphate homeostasis protein 0.47 OKFHMN_27740 mlc DNA-binding transcriptional repressor Mlc low > 79
Rahnella sp. WP5 0.57 EX31_RS02685 YggS family pyridoxal phosphate-dependent enzyme 0.50 EX31_RS16985 ROK family transcriptional regulator low > 89
Serratia liquefaciens MT49 0.56 IAI46_21410 YggS family pyridoxal phosphate-dependent enzyme 0.50 IAI46_11685 ROK family transcriptional regulator low > 87
Enterobacter sp. TBS_079 0.56 MPMX20_03809 Pyridoxal phosphate homeostasis protein 0.47 MPMX20_02063 Protein mlc low > 85
Erwinia tracheiphila SCR3 0.55 LU632_RS05460 YggS family pyridoxal phosphate-dependent enzyme 0.47 LU632_RS12305 ROK family transcriptional regulator 0.49 55
Erwinia tracheiphila HP pepo 2.2 0.55 IJEDHG_03450 YggS family pyridoxal phosphate enzyme 0.47 IJEDHG_23280 transcriptional regulator low > 61
Klebsiella pneumoniae MKP103 0.55 KDGMDA_04615 YggS family pyridoxal phosphate enzyme 0.48 KDGMDA_21230 transcriptional regulator low > 95
Erwinia amylovora T8 0.55 OLJFJH_08530 YggS family pyridoxal phosphate enzyme 0.48 OLJFJH_14275 transcriptional regulator low > 58
Variovorax sp. OAS795 0.50 ABID97_RS00250 YggS family pyridoxal phosphate-dependent enzyme 0.17 ABID97_RS00440 ROK family protein — —
Azospirillum brasilense Sp245 0.32 AZOBR_RS01870 alanine racemase 0.17 AZOBR_RS27950 transcriptional regulator — —
Bosea sp. OAE506 0.29 ABIE41_RS04720 YggS family pyridoxal phosphate-dependent enzyme 0.18 ABIE41_RS06840 ROK family protein low > 77
Sinorhizobium meliloti 1021 0.28 SMc02812 hypothetical protein 0.15 SMa2303 ROK family transcriptional regulator low > 103
Phaeobacter inhibens DSM 17395 0.27 PGA1_c33360 putative alanine racemase 0.19 PGA1_262p00420 Transcriptional regulator/sugar kinase low > 62
Parabacteroides merdae CL09T00C40 0.27 HMPREF1078_RS15965 YggS family pyridoxal phosphate-dependent enzyme 0.19 HMPREF1078_RS06205 ROK family transcriptional regulator low > 61
Bacteroides thetaiotaomicron VPI-5482 0.27 BT1332 conserved hypothetical protein (NCBI ptt file) 0.17 BT0433 putative xylose repressor (NCBI ptt file) — —
Dyella japonica UNC79MFTsu3.2 0.27 ABZR86_RS09305 YggS family pyridoxal phosphate-dependent enzyme 0.14 ABZR86_RS19180 ROK family transcriptional regulator — —
Phocaeicola vulgatus CL09T03C04 0.26 HMPREF1058_RS06240 YggS family pyridoxal phosphate-dependent enzyme 0.18 HMPREF1058_RS07285 ROK family transcriptional regulator low > 67
Caulobacter crescentus NA1000 Δfur 0.26 CCNA_03861 pyridoxal 5'-phosphate dependent enzyme class III 0.09 CCNA_01870 NagC-family transcriptional regulator low > 67
Bifidobacterium breve UCC2003 0.26 BBR_RS11570 YggS family pyridoxal phosphate-dependent enzyme 0.18 BBR_RS16880 ROK family transcriptional regulator low > 34
Phocaeicola dorei CL03T12C01 0.26 ABI39_RS20000 YggS family pyridoxal phosphate-dependent enzyme 0.18 ABI39_RS21185 ROK family transcriptional regulator low > 72
Caulobacter crescentus NA1000 0.26 CCNA_03861 pyridoxal 5'-phosphate dependent enzyme class III 0.09 CCNA_01870 NagC-family transcriptional regulator low > 66
Pontibacter actiniarum KMM 6156, DSM 19842 0.26 CA264_06410 YggS family pyridoxal phosphate enzyme 0.20 CA264_08710 sugar kinase low > 74
Bacteroides stercoris CC31F 0.24 HMPREF1181_RS10865 YggS family pyridoxal phosphate-dependent enzyme 0.17 HMPREF1181_RS04110 ROK family transcriptional regulator low > 56
Bacteroides ovatus ATCC 8483 0.24 BACOVA_00593 pyridoxal phosphate enzyme, YggS family 0.18 BACOVA_01791 hypothetical protein low > 96

Not shown: 76 genomes with orthologs for CSW01_02455 only; 0 genomes with orthologs for CSW01_10020 only