| Organism | Ratio1 | Gene1 | Name1 | Description1 | Ratio2 | Gene2 | Name2 | Description2 | Cofit | Rank |
| Vibrio cholerae E7946 ATCC 55056 | 1.0 | CSW01_06870 | | 7-carboxy-7-deazaguanine synthase QueE | 1.0 | CSW01_08745 | | TetR/AcrR family transcriptional regulator | 0.40 | 17 |
| Shewanella oneidensis MR-1 | 0.60 | SO2501 | | radical activating enzyme (NCBI ptt file) | 0.50 | SO2493 | | transcriptional regulator, TetR family (NCBI ptt file) | low | > 76 |
| Shewanella sp. ANA-3 | 0.59 | Shewana3_2163 | | radical activating enzyme (RefSeq) | 0.50 | Shewana3_2155 | | TetR family transcriptional regulator (RefSeq) | low | > 73 |
| Pectobacterium carotovorum WPP14 | 0.59 | HER17_RS04200 | | 7-carboxy-7-deazaguanine synthase QueE | 0.17 | HER17_RS16470 | | TetR/AcrR family transcriptional regulator | low | > 75 |
| Shewanella loihica PV-4 | 0.56 | Shew_2061 | | radical SAM domain-containing protein (RefSeq) | 0.51 | Shew_2052 | | TetR family transcriptional regulator (RefSeq) | low | > 60 |
| Dickeya dianthicola 67-19 | 0.56 | HGI48_RS17035 | | 7-carboxy-7-deazaguanine synthase QueE | 0.17 | HGI48_RS11790 | | TetR family transcriptional regulator | low | > 71 |
| Dickeya dianthicola ME23 | 0.56 | DZA65_RS18110 | | 7-carboxy-7-deazaguanine synthase QueE | 0.16 | DZA65_RS12330 | | TetR family transcriptional regulator | low | > 75 |
| Shewanella amazonensis SB2B | 0.55 | Sama_1825 | | radical activating enzyme (RefSeq) | 0.50 | Sama_1816 | | TetR family transcriptional regulator (RefSeq) | low | > 62 |
| Alteromonas macleodii MIT1002 | 0.51 | MIT1002_01264 | | 7-carboxy-7-deazaguanine synthase | 0.44 | MIT1002_01970 | | Stress response protein YttP | low | > 70 |
| Variovorax sp. SCN45 | 0.16 | GFF2577 | | 7-carboxy-7-deazaguanine synthase (EC 4.3.99.3) | 0.14 | GFF3420 | | Transcriptional regulator, AcrR family | — | — |
| Caulobacter crescentus NA1000 Δfur | 0.14 | CCNA_03261 | | queuosine biosynthesis protein QueE | 0.21 | CCNA_02161 | | TetR-family transcriptional regulator | low | > 67 |
| Caulobacter crescentus NA1000 | 0.14 | CCNA_03261 | | queuosine biosynthesis protein QueE | 0.21 | CCNA_02161 | | TetR-family transcriptional regulator | low | > 66 |
| Rhodopseudomonas palustris CGA009 | 0.14 | TX73_006110 | | 7-carboxy-7-deazaguanine synthase | 0.16 | TX73_017010 | | TetR/AcrR family transcriptional regulator | low | > 86 |
| Pseudomonas sp. RS175 | 0.14 | PFR28_03404 | | 7-carboxy-7-deazaguanine synthase | 0.35 | PFR28_01118 | | hypothetical protein | low | > 88 |
| Brevundimonas sp. GW460-12-10-14-LB2 | 0.14 | A4249_RS08695 | | 7-carboxy-7-deazaguanine synthase | 0.14 | A4249_RS14405 | | TetR/AcrR family transcriptional regulator | — | — |
| Pseudomonas sp. DMC3 | 0.14 | GFF5176 | | 7-carboxy-7-deazaguanine synthase | 0.35 | GFF1279 | | hypothetical protein | low | > 89 |
| Rhodanobacter sp. FW510-T8 | 0.14 | OKGIIK_01890 | | 7-carboxy-7-deazaguanine synthase | 0.24 | OKGIIK_07150 | acrR | DNA-binding protein, AcrR family, includes nucleoid occlusion protein SlmA | low | > 53 |
| Pseudomonas lactucae CFBP13502 | 0.13 | GEMAOFIL_04633 | | 7-carboxy-7-deazaguanine synthase | 0.36 | GEMAOFIL_01655 | | hypothetical protein | low | > 96 |
| Pseudomonas simiae WCS417 | 0.13 | PS417_22405 | | 7-carboxy-7-deazaguanine synthase | 0.36 | PS417_07615 | | TetR family transcriptional regulator | 0.34 | 34 |
| Pseudomonas orientalis W4I3 | 0.13 | QF045_RS24570 | | 7-carboxy-7-deazaguanine synthase QueE | 0.35 | QF045_RS10255 | | TetR/AcrR family transcriptional regulator | low | > 93 |
| Dechlorosoma suillum PS | 0.13 | Dsui_0476 | | organic radical activating enzyme | 0.25 | Dsui_0327 | | transcriptional regulator | low | > 51 |
| Pseudomonas fluorescens SBW25 | 0.13 | PFLU_RS24045 | | 7-carboxy-7-deazaguanine synthase QueE | 0.35 | PFLU_RS07690 | | helix-turn-helix transcriptional regulator | low | > 109 |
| Pseudomonas fluorescens SBW25-INTG | 0.13 | PFLU_RS24045 | | 7-carboxy-7-deazaguanine synthase QueE | 0.35 | PFLU_RS07690 | | helix-turn-helix transcriptional regulator | low | > 109 |
| Rhodanobacter sp000427505 FW510-R12 | 0.13 | LRK53_RS05170 | | 7-carboxy-7-deazaguanine synthase QueE | 0.24 | LRK53_RS11205 | | TetR/AcrR family transcriptional regulator | low | > 59 |
| Hydrogenophaga sp. GW460-11-11-14-LB1 | 0.13 | GFF4633 | | Queuosine Biosynthesis QueE Radical SAM | 0.18 | GFF2284 | | transcriptional regulator, TetR family | low | > 90 |
| Dyella japonica UNC79MFTsu3.2 | 0.13 | ABZR86_RS10790 | | 7-carboxy-7-deazaguanine synthase QueE | 0.24 | ABZR86_RS05465 | | TetR/AcrR family transcriptional regulator | low | > 74 |
| Pseudomonas fluorescens FW300-N2C3 | 0.13 | AO356_18065 | | 7-carboxy-7-deazaguanine synthase | 0.35 | AO356_02290 | | TetR family transcriptional regulator | low | > 104 |
| Pseudomonas fluorescens FW300-N2E2 | 0.13 | Pf6N2E2_5545 | | Queuosine Biosynthesis QueE Radical SAM | 0.35 | Pf6N2E2_2282 | | Predicted transcriptional regulator for fatty acid degradation FadQ, TetR family | low | > 103 |
| Pseudomonas putida KT2440 | 0.12 | PP_1225 | | 7-carboxy-7-deazaguanine synthase | 0.36 | PP_2144 | | Transcriptional regulator, TetR family | low | > 96 |
| Pseudomonas sp. S08-1 | 0.12 | OH686_19175 | | 7-carboxy-7-deazaguanine synthase | 0.35 | OH686_21965 | | Predicted transcriptional regulator for fatty acid degradation FadQ, TetR family | low | > 80 |
| Pseudomonas fluorescens GW456-L13 | 0.12 | PfGW456L13_1861 | | Queuosine Biosynthesis QueE Radical SAM | 0.35 | PfGW456L13_4033 | | Predicted transcriptional regulator for fatty acid degradation FadQ, TetR family | low | > 87 |
| Pseudomonas aeruginosa PA14 | 0.12 | IKLFDK_04415 | | 7-carboxy-7-deazaguanine synthase QueE | 0.36 | IKLFDK_15295 | | transcriptional regulator PsrA | low | > 98 |
| Pseudomonas sp. BP01 | 0.12 | JOY50_RS01775 | queE | 7-carboxy-7-deazaguanine synthase QueE | 0.35 | JOY50_RS25075 | | TetR/AcrR family transcriptional regulator | low | > 84 |
| Pseudomonas fluorescens FW300-N1B4 | 0.12 | Pf1N1B4_629 | | Queuosine Biosynthesis QueE Radical SAM | 0.35 | Pf1N1B4_3911 | | Predicted transcriptional regulator for fatty acid degradation FadQ, TetR family | low | > 87 |
| Pseudomonas aeruginosa MRSN321 | 0.12 | DY961_RS07555 | queE;go_function=4 | 7-carboxy-7-deazaguanine synthase QueE | 0.36 | DY961_RS01935 | psrA;inference=COORDINATES | transcriptional regulator PsrA | low | > 100 |
| Pseudomonas aeruginosa PUPa3 | 0.12 | DQ20_RS45235 | queE;go_function=4 | 7-carboxy-7-deazaguanine synthase QueE | 0.35 | DQ20_RS33645 | psrA;inference=COORDINATES | transcriptional regulator PsrA | low | > 101 |
| Kangiella aquimarina DSM 16071 | 0.12 | B158DRAFT_1144 | | Organic radical activating enzymes | 0.42 | B158DRAFT_2232 | | transcriptional regulator, TetR family | low | > 40 |
| Pseudomonas segetis P6 | 0.12 | MPMX49_01693 | | 7-carboxy-7-deazaguanine synthase | 0.34 | MPMX49_02987 | | hypothetical protein | low | > 75 |
| Lysobacter sp. OAE881 | 0.11 | ABIE51_RS05100 | | 7-carboxy-7-deazaguanine synthase QueE | 0.26 | ABIE51_RS09405 | | TetR family transcriptional regulator | low | > 62 |
Not shown: 60 genomes with orthologs for CSW01_06870 only; 9 genomes with orthologs for CSW01_08745 only