| Organism | Ratio1 | Gene1 | Name1 | Description1 | Ratio2 | Gene2 | Name2 | Description2 | Cofit | Rank |
| Vibrio cholerae E7946 ATCC 55056 | 1.0 | CSW01_01725 | | TetR family transcriptional regulator | 1.0 | CSW01_06455 | | DNA-binding response regulator | 0.48 | 14 |
| Shewanella amazonensis SB2B | 0.35 | Sama_0099 | | TetR family transcriptional regulator (RefSeq) | 0.30 | Sama_1873 | | response regulator receiver protein (RefSeq) | low | > 62 |
| Pseudomonas sp. BP01 | 0.29 | JOY50_RS20790 | | TetR/AcrR family transcriptional regulator | 0.29 | JOY50_RS24990 | | response regulator transcription factor | low | > 84 |
| Pseudomonas putida KT2440 | 0.29 | PP_5119 | | Transcriptional regulator, TetR family | 0.30 | PP_2126 | | DNA-binding response regulator, LuxR family | low | > 96 |
| Pseudomonas fluorescens FW300-N2E3 | 0.29 | AO353_08285 | | TetR family transcriptional regulator | 0.36 | AO353_25245 | | regulator | low | > 101 |
| Pseudomonas sp. RS175 | 0.28 | PFR28_04265 | | hypothetical protein | 0.38 | PFR28_01618 | | Oxygen regulatory protein NreC | low | > 88 |
| Pseudomonas fluorescens SBW25-INTG | 0.28 | PFLU_RS28485 | | TetR/AcrR family transcriptional regulator | 0.29 | PFLU_RS14300 | | response regulator transcription factor | low | > 109 |
| Pseudomonas syringae pv. syringae B728a ΔmexB | 0.28 | Psyr_4757 | | transcriptional regulator, TetR family | 0.30 | Psyr_1940 | | regulatory protein, LuxR:Response regulator receiver | — | — |
| Pseudomonas fluorescens SBW25 | 0.28 | PFLU_RS28485 | | TetR/AcrR family transcriptional regulator | 0.29 | PFLU_RS14300 | | response regulator transcription factor | — | — |
| Pseudomonas syringae pv. syringae B728a | 0.28 | Psyr_4757 | | transcriptional regulator, TetR family | 0.30 | Psyr_1940 | | regulatory protein, LuxR:Response regulator receiver | — | — |
| Pseudomonas fluorescens FW300-N1B4 | 0.27 | Pf1N1B4_2316 | | Transcriptional regulator, TetR family | 0.38 | Pf1N1B4_4833 | | DNA-binding response regulator, LuxR family | low | > 87 |
| Pseudomonas fluorescens FW300-N2C3 | 0.27 | AO356_13305 | | TetR family transcriptional regulator | 0.36 | AO356_25670 | | regulator | low | > 104 |
| Pseudomonas fluorescens FW300-N2E2 | 0.27 | Pf6N2E2_4576 | | Transcriptional regulator, TetR family | 0.38 | Pf6N2E2_1296 | | DNA-binding response regulator, LuxR family | low | > 103 |
| Pseudomonas lactucae CFBP13502 | 0.27 | GEMAOFIL_05505 | | hypothetical protein | 0.30 | GEMAOFIL_03209 | | Transcriptional regulatory protein LnrK | low | > 93 |
| Ralstonia solanacearum UW163 | 0.23 | UW163_RS10630 | | TetR family transcriptional regulator | 0.38 | UW163_RS04080 | | DNA-binding response regulator | — | — |
| Ralstonia solanacearum IBSBF1503 | 0.23 | RALBFv3_RS03095 | | TetR family transcriptional regulator | 0.38 | RALBFv3_RS09500 | | DNA-binding response regulator | low | > 76 |
| Ralstonia sp. UNC404CL21Col | 0.23 | ABZR87_RS15000 | | TetR/AcrR family transcriptional regulator | 0.38 | ABZR87_RS05230 | | response regulator transcription factor | low | > 80 |
| Cupriavidus basilensis FW507-4G11 | 0.23 | RR42_RS05390 | | TetR family transcriptional regulator | 0.33 | RR42_RS20525 | | LuxR family transcriptional regulator | low | > 128 |
| Ralstonia solanacearum PSI07 | 0.23 | RPSI07_RS14210 | | TetR family transcriptional regulator | 0.38 | RPSI07_RS23850 | | DNA-binding response regulator | low | > 81 |
| Ralstonia solanacearum GMI1000 | 0.23 | RS_RS10465 | | TetR family transcriptional regulator | 0.38 | RS_RS00100 | | DNA-binding response regulator | low | > 80 |
| Paraburkholderia sabiae LMG 24235 | 0.22 | QEN71_RS24285 | | TetR/AcrR family transcriptional regulator | 0.39 | QEN71_RS32890 | | response regulator transcription factor | low | > 153 |
| Lysobacter sp. OAE881 | 0.22 | ABIE51_RS12300 | | TetR/AcrR family transcriptional regulator | 0.33 | ABIE51_RS10320 | | response regulator transcription factor | low | > 62 |
| Paraburkholderia bryophila 376MFSha3.1 | 0.22 | H281DRAFT_04543 | | transcriptional regulator, TetR family | 0.39 | H281DRAFT_03153 | | two component transcriptional regulator, LuxR family | low | > 103 |
| Burkholderia phytofirmans PsJN | 0.21 | BPHYT_RS06505 | | TetR family transcriptional regulator | 0.35 | BPHYT_RS22230 | | LuxR family transcriptional regulator | low | > 109 |
| Agrobacterium fabrum C58 | 0.19 | Atu1568 | | transcriptional regulator, TetR family | 0.40 | Atu5267 | | two component response regulator | — | — |
| Hydrogenophaga sp. GW460-11-11-14-LB1 | 0.17 | GFF404 | | Transcriptional regulator, TetR family | 0.32 | GFF3272 | | DNA-binding response regulator, LuxR family | low | > 90 |
| Echinicola vietnamensis KMM 6221, DSM 17526 | 0.14 | Echvi_1257 | | Transcriptional regulator | 0.39 | Echvi_1897 | | Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain | low | > 79 |
| Alteromonas macleodii MIT1002 | 0.13 | MIT1002_02572 | | HTH-type transcriptional regulator QacR | 0.33 | MIT1002_03526 | | Nitrogen regulation protein C | low | > 70 |
Not shown: 11 genomes with orthologs for CSW01_01725 only; 34 genomes with orthologs for CSW01_06455 only