Conservation of cofitness between BWI76_RS04245 and BWI76_RS04670 in Klebsiella michiganensis M5al

41 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Klebsiella michiganensis M5al 1.0 BWI76_RS04245 bifunctional aspartate kinase/homoserine dehydrogenase I 1.0 BWI76_RS04670 3-isopropylmalate dehydratase large subunit 0.94 11
Escherichia coli BW25113 0.92 b0002 thrA bifunctional aspartokinase I/homeserine dehydrogenase I (NCBI) 0.95 b0072 leuC isopropylmalate isomerase large subunit (NCBI) 0.91 27
Escherichia coli ECOR38 0.92 HEPCGN_09115 thrA bifunctional aspartate kinase/homoserine dehydrogenase I 0.95 HEPCGN_08705 leuC1 3-isopropylmalate dehydratase large subunit 1 0.95 25
Escherichia coli ECRC98 0.92 JDDGAC_14705 thrA bifunctional aspartate kinase/homoserine dehydrogenase I 0.95 JDDGAC_14320 leuC1 3-isopropylmalate dehydratase large subunit 1 0.94 11
Escherichia coli ECRC102 0.92 NIAGMN_08960 thrA bifunctional aspartate kinase/homoserine dehydrogenase I 0.95 NIAGMN_08575 leuC1 3-isopropylmalate dehydratase large subunit 1 — —
Escherichia coli ECRC101 0.92 MCAODC_01625 thrA bifunctional aspartate kinase/homoserine dehydrogenase I 0.95 MCAODC_01240 leuC1 3-isopropylmalate dehydratase large subunit 1 0.80 42
Escherichia coli ECRC99 0.92 KEDOAH_17045 thrA bifunctional aspartate kinase/homoserine dehydrogenase I 0.95 KEDOAH_17430 leuC1 3-isopropylmalate dehydratase large subunit 1 — —
Escherichia coli ECRC100 0.92 OKFHMN_11110 thrA bifunctional aspartate kinase/homoserine dehydrogenase I 0.95 OKFHMN_10725 leuC1 3-isopropylmalate dehydratase large subunit 1 0.97 39
Escherichia fergusonii Becca 0.92 EFB2_04041 Bifunctional aspartokinase/homoserine dehydrogenase 1 0.95 EFB2_03973 3-isopropylmalate dehydratase large subunit low > 86
Escherichia coli HS(pFamp)R (ATCC 700891) 0.92 OHPLBJKB_03658 Bifunctional aspartokinase/homoserine dehydrogenase 1 0.95 OHPLBJKB_03585 3-isopropylmalate dehydratase large subunit low > 73
Escherichia coli BL21 0.92 ECD_00002 Bifunctional aspartokinase/homoserine dehydrogenase 1 0.95 ECD_00074 3-isopropylmalate dehydratase large subunit 0.97 6
Escherichia coli ECRC62 0.92 BNILDI_08160 thrA bifunctional aspartate kinase/homoserine dehydrogenase I 0.95 BNILDI_08540 leuC1 3-isopropylmalate dehydratase large subunit 1 0.99 8
Escherichia coli ECOR27 0.92 NOLOHH_03440 thrA bifunctional aspartate kinase/homoserine dehydrogenase I 0.95 NOLOHH_03070 leuC1 3-isopropylmalate dehydratase large subunit 1 0.92 32
Escherichia coli Nissle 1917 0.92 ECOLIN_RS00010 bifunctional aspartate kinase/homoserine dehydrogenase I 0.95 ECOLIN_RS00390 3-isopropylmalate dehydratase large subunit low > 55
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.92 GFF1078 Aspartokinase (EC 2.7.2.4) / Homoserine dehydrogenase (EC 1.1.1.3) 0.94 GFF166 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33) low > 78
Enterobacter sp. TBS_079 0.90 MPMX20_00710 Bifunctional aspartokinase/homoserine dehydrogenase 1 0.95 MPMX20_00767 3-isopropylmalate dehydratase large subunit 1 0.93 11
Enterobacter asburiae PDN3 0.89 EX28DRAFT_3614 aspartate kinase (EC 2.7.2.4) 0.95 EX28DRAFT_3668 3-isopropylmalate dehydratase, large subunit 0.70 46
Rahnella sp. WP5 0.85 EX31_RS03945 bifunctional aspartate kinase/homoserine dehydrogenase I 0.87 EX31_RS03690 3-isopropylmalate dehydratase large subunit 0.98 4
Pantoea sp. MT58 0.84 IAI47_16215 bifunctional aspartate kinase/homoserine dehydrogenase I 0.86 IAI47_16010 3-isopropylmalate dehydratase large subunit 0.97 6
Serratia liquefaciens MT49 0.84 IAI46_03030 bifunctional aspartate kinase/homoserine dehydrogenase I 0.85 IAI46_03345 3-isopropylmalate dehydratase large subunit 0.76 34
Pectobacterium carotovorum WPP14 0.83 HER17_RS02795 bifunctional aspartate kinase/homoserine dehydrogenase I 0.85 HER17_RS03075 3-isopropylmalate dehydratase large subunit 0.93 22
Erwinia tracheiphila SCR3 0.83 LU632_RS02610 thrA bifunctional aspartate kinase/homoserine dehydrogenase I 0.79 LU632_RS02870 leuC 3-isopropylmalate dehydratase large subunit 0.83 11
Dickeya dadantii 3937 0.80 DDA3937_RS18415 bifunctional aspartate kinase/homoserine dehydrogenase I 0.85 DDA3937_RS18125 3-isopropylmalate dehydratase large subunit low > 74
Dickeya dianthicola ME23 0.80 DZA65_RS19485 bifunctional aspartate kinase/homoserine dehydrogenase I 0.85 DZA65_RS19210 3-isopropylmalate dehydratase large subunit 0.83 24
Dickeya dianthicola 67-19 0.80 HGI48_RS18345 bifunctional aspartate kinase/homoserine dehydrogenase I 0.85 HGI48_RS18065 3-isopropylmalate dehydratase large subunit 0.77 47
Vibrio cholerae E7946 ATCC 55056 0.62 CSW01_11975 bifunctional aspartate kinase/homoserine dehydrogenase I 0.79 CSW01_12605 3-isopropylmalate dehydratase large subunit low > 62
Shewanella loihica PV-4 0.57 Shew_1079 thrA bifunctional aspartokinase I/homeserine dehydrogenase I (RefSeq) 0.71 Shew_3470 isopropylmalate isomerase large subunit (RefSeq) 0.98 13
Shewanella oneidensis MR-1 0.56 SO3415 thrA aspartokinase I/homoserine dehydrogenase, threonine-sensitive (NCBI ptt file) 0.73 SO4234 leuC 3-isopropylmalate dehydratase, large subunit (NCBI ptt file) 0.86 18
Shewanella sp. ANA-3 0.56 Shewana3_1139 thrA bifunctional aspartokinase I/homeserine dehydrogenase I (RefSeq) 0.73 Shewana3_3759 isopropylmalate isomerase large subunit (RefSeq) 0.92 26
Alteromonas macleodii MIT1002 0.53 MIT1002_03086 Aspartokinase I/homoserine dehydrogenase I 0.68 MIT1002_00947 3-isopropylmalate dehydratase large subunit 0.98 21
Shewanella amazonensis SB2B 0.53 Sama_0905 thrA bifunctional aspartokinase I/homeserine dehydrogenase I (RefSeq) 0.72 Sama_0337 isopropylmalate isomerase large subunit (RefSeq) 0.90 38
Echinicola vietnamensis KMM 6221, DSM 17526 0.34 Echvi_2000 aspartate kinase / homoserine dehydrogenase (EC 2.7.2.4; EC 1.1.1.3) (from data) 0.53 Echvi_2059 3-isopropylmalate dehydratase, large subunit 0.74 49
Xanthomonas campestris pv. campestris strain 8004 0.33 Xcc-8004.2957.1 Aspartokinase (EC 2.7.2.4) / Homoserine dehydrogenase (EC 1.1.1.3) 0.62 Xcc-8004.1049.1 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33) 0.76 40
Mucilaginibacter yixingensis YX-36 DSM 26809 0.32 ABZR88_RS18950 bifunctional aspartate kinase/homoserine dehydrogenase I 0.57 ABZR88_RS11595 3-isopropylmalate dehydratase large subunit — —
Phocaeicola vulgatus CL09T03C04 0.32 HMPREF1058_RS14720 bifunctional aspartate kinase/homoserine dehydrogenase I 0.50 HMPREF1058_RS14550 3-isopropylmalate dehydratase large subunit 0.81 36
Pedobacter sp. GW460-11-11-14-LB5 0.32 CA265_RS23475 aspartate kinase; homoserine dehydrogenase (EC 2.7.2.4; EC 1.1.1.3) (from data) 0.57 CA265_RS15830 3-isopropylmalate dehydratase large subunit 0.95 20
Phocaeicola dorei CL03T12C01 0.32 ABI39_RS10430 bifunctional aspartate kinase/homoserine dehydrogenase I 0.50 ABI39_RS10200 3-isopropylmalate dehydratase large subunit 0.89 11
Parabacteroides merdae CL09T00C40 0.31 HMPREF1078_RS10385 bifunctional aspartate kinase/homoserine dehydrogenase I 0.49 HMPREF1078_RS16660 3-isopropylmalate dehydratase large subunit 0.95 41
Lysobacter sp. OAE881 0.30 ABIE51_RS17520 bifunctional aspartate kinase/homoserine dehydrogenase I 0.52 ABIE51_RS17575 3-isopropylmalate dehydratase large subunit 0.95 40
Bacteroides stercoris CC31F 0.28 HMPREF1181_RS00060 bifunctional aspartate kinase/homoserine dehydrogenase I 0.51 HMPREF1181_RS14145 3-isopropylmalate dehydratase large subunit 0.94 26
Bacteroides thetaiotaomicron VPI-5482 0.28 BT2403 aspartate kinase / homoserine dehydrogenase (EC 2.7.2.4; EC 1.1.1.3) (from data) 0.50 BT1860 3-isopropylmalate dehydratase large subunit (NCBI ptt file) 0.89 11
Bacteroides ovatus ATCC 8483 0.28 BACOVA_03021 homoserine dehydrogenase 0.51 BACOVA_04603 3-isopropylmalate dehydratase, large subunit 0.96 6

Not shown: 0 genomes with orthologs for BWI76_RS04245 only; 61 genomes with orthologs for BWI76_RS04670 only