Conservation of cofitness between BWI76_RS04245 and BWI76_RS04665 in Klebsiella michiganensis M5al

41 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Klebsiella michiganensis M5al 1.0 BWI76_RS04245 bifunctional aspartate kinase/homoserine dehydrogenase I 1.0 BWI76_RS04665 3-isopropylmalate dehydratase small subunit 0.96 4
Escherichia coli ECOR38 0.92 HEPCGN_09115 thrA bifunctional aspartate kinase/homoserine dehydrogenase I 0.88 HEPCGN_08710 leuD 3-isopropylmalate dehydratase small subunit 0.92 46
Escherichia coli BW25113 0.92 b0002 thrA bifunctional aspartokinase I/homeserine dehydrogenase I (NCBI) 0.88 b0071 leuD isopropylmalate isomerase small subunit (NCBI) 0.90 38
Escherichia coli ECRC100 0.92 OKFHMN_11110 thrA bifunctional aspartate kinase/homoserine dehydrogenase I 0.87 OKFHMN_10730 leuD 3-isopropylmalate dehydratase small subunit 0.97 40
Escherichia coli ECRC102 0.92 NIAGMN_08960 thrA bifunctional aspartate kinase/homoserine dehydrogenase I 0.87 NIAGMN_08580 leuD 3-isopropylmalate dehydratase small subunit — —
Escherichia coli ECRC101 0.92 MCAODC_01625 thrA bifunctional aspartate kinase/homoserine dehydrogenase I 0.87 MCAODC_01245 leuD 3-isopropylmalate dehydratase small subunit 0.82 28
Escherichia coli ECRC98 0.92 JDDGAC_14705 thrA bifunctional aspartate kinase/homoserine dehydrogenase I 0.87 JDDGAC_14325 leuD 3-isopropylmalate dehydratase small subunit 0.91 32
Escherichia coli ECRC99 0.92 KEDOAH_17045 thrA bifunctional aspartate kinase/homoserine dehydrogenase I 0.87 KEDOAH_17425 leuD 3-isopropylmalate dehydratase small subunit — —
Escherichia fergusonii Becca 0.92 EFB2_04041 Bifunctional aspartokinase/homoserine dehydrogenase 1 0.88 EFB2_03974 3-isopropylmalate dehydratase small subunit low > 86
Escherichia coli ECOR27 0.92 NOLOHH_03440 thrA bifunctional aspartate kinase/homoserine dehydrogenase I 0.88 NOLOHH_03075 leuD 3-isopropylmalate dehydratase small subunit 0.91 34
Escherichia coli ECRC62 0.92 BNILDI_08160 thrA bifunctional aspartate kinase/homoserine dehydrogenase I 0.88 BNILDI_08535 leuD 3-isopropylmalate dehydratase small subunit 0.95 50
Escherichia coli HS(pFamp)R (ATCC 700891) 0.92 OHPLBJKB_03658 Bifunctional aspartokinase/homoserine dehydrogenase 1 0.88 OHPLBJKB_03586 3-isopropylmalate dehydratase small subunit low > 73
Escherichia coli BL21 0.92 ECD_00002 Bifunctional aspartokinase/homoserine dehydrogenase 1 0.88 ECD_00073 3-isopropylmalate dehydratase small subunit 0.92 19
Escherichia coli Nissle 1917 0.92 ECOLIN_RS00010 bifunctional aspartate kinase/homoserine dehydrogenase I 0.88 ECOLIN_RS00385 3-isopropylmalate dehydratase small subunit low > 55
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.92 GFF1078 Aspartokinase (EC 2.7.2.4) / Homoserine dehydrogenase (EC 1.1.1.3) 0.93 GFF167 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33) low > 78
Enterobacter sp. TBS_079 0.90 MPMX20_00710 Bifunctional aspartokinase/homoserine dehydrogenase 1 0.93 MPMX20_00766 3-isopropylmalate dehydratase small subunit 1 0.93 16
Enterobacter asburiae PDN3 0.89 EX28DRAFT_3614 aspartate kinase (EC 2.7.2.4) 0.92 EX28DRAFT_3667 3-isopropylmalate dehydratase, small subunit 0.67 52
Rahnella sp. WP5 0.85 EX31_RS03945 bifunctional aspartate kinase/homoserine dehydrogenase I 0.84 EX31_RS03695 3-isopropylmalate dehydratase small subunit 0.96 36
Pantoea sp. MT58 0.84 IAI47_16215 bifunctional aspartate kinase/homoserine dehydrogenase I 0.83 IAI47_16015 3-isopropylmalate dehydratase small subunit 0.95 12
Serratia liquefaciens MT49 0.84 IAI46_03030 bifunctional aspartate kinase/homoserine dehydrogenase I 0.84 IAI46_03340 3-isopropylmalate dehydratase small subunit low > 86
Pectobacterium carotovorum WPP14 0.83 HER17_RS02795 bifunctional aspartate kinase/homoserine dehydrogenase I 0.84 HER17_RS03070 3-isopropylmalate dehydratase small subunit 0.91 39
Erwinia tracheiphila SCR3 0.83 LU632_RS02610 thrA bifunctional aspartate kinase/homoserine dehydrogenase I 0.74 LU632_RS02865 leuD 3-isopropylmalate dehydratase small subunit 0.80 17
Dickeya dadantii 3937 0.80 DDA3937_RS18415 bifunctional aspartate kinase/homoserine dehydrogenase I 0.84 DDA3937_RS18130 3-isopropylmalate dehydratase small subunit low > 74
Dickeya dianthicola 67-19 0.80 HGI48_RS18345 bifunctional aspartate kinase/homoserine dehydrogenase I 0.83 HGI48_RS18070 3-isopropylmalate dehydratase small subunit 0.77 50
Dickeya dianthicola ME23 0.80 DZA65_RS19485 bifunctional aspartate kinase/homoserine dehydrogenase I 0.84 DZA65_RS19215 3-isopropylmalate dehydratase small subunit 0.84 23
Vibrio cholerae E7946 ATCC 55056 0.62 CSW01_11975 bifunctional aspartate kinase/homoserine dehydrogenase I 0.73 CSW01_12610 3-isopropylmalate dehydratase small subunit low > 62
Shewanella loihica PV-4 0.57 Shew_1079 thrA bifunctional aspartokinase I/homeserine dehydrogenase I (RefSeq) 0.63 Shew_3469 isopropylmalate isomerase small subunit (RefSeq) 0.97 27
Shewanella oneidensis MR-1 0.56 SO3415 thrA aspartokinase I/homoserine dehydrogenase, threonine-sensitive (NCBI ptt file) 0.60 SO4233 leuD 3-isopropylmalate dehydratase, small subunit (NCBI ptt file) 0.85 24
Shewanella sp. ANA-3 0.56 Shewana3_1139 thrA bifunctional aspartokinase I/homeserine dehydrogenase I (RefSeq) 0.59 Shewana3_3758 leuD isopropylmalate isomerase small subunit (RefSeq) 0.93 20
Alteromonas macleodii MIT1002 0.53 MIT1002_03086 Aspartokinase I/homoserine dehydrogenase I 0.62 MIT1002_00946 3-isopropylmalate dehydratase small subunit 1 0.94 47
Shewanella amazonensis SB2B 0.53 Sama_0905 thrA bifunctional aspartokinase I/homeserine dehydrogenase I (RefSeq) 0.60 Sama_0338 leuD isopropylmalate isomerase small subunit (RefSeq) 0.90 41
Echinicola vietnamensis KMM 6221, DSM 17526 0.34 Echvi_2000 aspartate kinase / homoserine dehydrogenase (EC 2.7.2.4; EC 1.1.1.3) (from data) 0.38 Echvi_2060 3-isopropylmalate dehydratase, small subunit — —
Xanthomonas campestris pv. campestris strain 8004 0.33 Xcc-8004.2957.1 Aspartokinase (EC 2.7.2.4) / Homoserine dehydrogenase (EC 1.1.1.3) 0.61 Xcc-8004.1050.1 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33) 0.73 54
Mucilaginibacter yixingensis YX-36 DSM 26809 0.32 ABZR88_RS18950 bifunctional aspartate kinase/homoserine dehydrogenase I 0.45 ABZR88_RS11600 3-isopropylmalate dehydratase small subunit — —
Phocaeicola vulgatus CL09T03C04 0.32 HMPREF1058_RS14720 bifunctional aspartate kinase/homoserine dehydrogenase I 0.42 HMPREF1058_RS14555 3-isopropylmalate dehydratase small subunit 0.80 40
Pedobacter sp. GW460-11-11-14-LB5 0.32 CA265_RS23475 aspartate kinase; homoserine dehydrogenase (EC 2.7.2.4; EC 1.1.1.3) (from data) 0.44 CA265_RS15840 3-isopropylmalate dehydratase small subunit 0.94 34
Phocaeicola dorei CL03T12C01 0.32 ABI39_RS10430 bifunctional aspartate kinase/homoserine dehydrogenase I 0.42 ABI39_RS10205 3-isopropylmalate dehydratase small subunit 0.84 27
Parabacteroides merdae CL09T00C40 0.31 HMPREF1078_RS10385 bifunctional aspartate kinase/homoserine dehydrogenase I 0.42 HMPREF1078_RS16655 3-isopropylmalate dehydratase small subunit low > 61
Lysobacter sp. OAE881 0.30 ABIE51_RS17520 bifunctional aspartate kinase/homoserine dehydrogenase I 0.42 ABIE51_RS17580 3-isopropylmalate dehydratase small subunit 0.90 53
Bacteroides stercoris CC31F 0.28 HMPREF1181_RS00060 bifunctional aspartate kinase/homoserine dehydrogenase I 0.43 HMPREF1181_RS14140 3-isopropylmalate dehydratase small subunit 0.88 47
Bacteroides thetaiotaomicron VPI-5482 0.28 BT2403 aspartate kinase / homoserine dehydrogenase (EC 2.7.2.4; EC 1.1.1.3) (from data) 0.39 BT1859 3-isopropylmalate dehydratase small subunit (NCBI ptt file) 0.90 10
Bacteroides ovatus ATCC 8483 0.28 BACOVA_03021 homoserine dehydrogenase 0.39 BACOVA_04602 3-isopropylmalate dehydratase, small subunit 0.95 21

Not shown: 0 genomes with orthologs for BWI76_RS04245 only; 57 genomes with orthologs for BWI76_RS04665 only