| Organism | Ratio1 | Gene1 | Name1 | Description1 | Ratio2 | Gene2 | Name2 | Description2 | Cofit | Rank |
|---|
| Klebsiella michiganensis M5al | 1.0 | BWI76_RS00805 | | 5,10-methylenetetrahydrofolate reductase | 1.0 | BWI76_RS04250 | | homoserine kinase | 0.90 | 13 |
| Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 | 0.96 | GFF2329 | | 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) | 0.90 | GFF1079 | | Homoserine kinase (EC 2.7.1.39) | low | > 78 |
| Enterobacter asburiae PDN3 | 0.95 | EX28DRAFT_4413 | | 5,10-methylenetetrahydrofolate reductase, prokaryotic form | 0.93 | EX28DRAFT_3615 | | homoserine kinase (EC 2.7.1.39) | — | — |
| Enterobacter sp. TBS_079 | 0.95 | MPMX20_04529 | | 5,10-methylenetetrahydrofolate reductase | 0.92 | MPMX20_00711 | | Homoserine kinase | 0.74 | 19 |
| Escherichia coli BW25113 | 0.95 | b3941 | metF | 5,10-methylenetetrahydrofolate reductase (NCBI) | 0.89 | b0003 | thrB | homoserine kinase (NCBI) | 0.93 | 37 |
| Escherichia coli HS(pFamp)R (ATCC 700891) | 0.95 | OHPLBJKB_04109 | | 5,10-methylenetetrahydrofolate reductase | 0.89 | OHPLBJKB_03657 | | Homoserine kinase | low | > 73 |
| Escherichia coli BL21 | 0.95 | ECD_03827 | | 5,10-methylenetetrahydrofolate reductase | 0.89 | ECD_00003 | | homoserine kinase | 0.95 | 9 |
| Escherichia coli ECRC62 | 0.95 | BNILDI_05725 | metF | methylenetetrahydrofolate reductase | 0.89 | BNILDI_08165 | thrB | homoserine kinase | 0.97 | 32 |
| Escherichia coli ECOR27 | 0.95 | NOLOHH_05810 | metF | methylenetetrahydrofolate reductase | 0.89 | NOLOHH_03435 | thrB | homoserine kinase | 0.90 | 49 |
| Escherichia coli ECRC101 | 0.95 | MCAODC_04165 | metF | methylenetetrahydrofolate reductase | 0.89 | MCAODC_01620 | thrB | homoserine kinase | 0.85 | 53 |
| Escherichia coli ECRC99 | 0.95 | KEDOAH_14495 | metF | methylenetetrahydrofolate reductase | 0.89 | KEDOAH_17050 | thrB | homoserine kinase | — | — |
| Escherichia coli ECRC100 | 0.95 | OKFHMN_13665 | metF | methylenetetrahydrofolate reductase | 0.89 | OKFHMN_11105 | thrB | homoserine kinase | 0.99 | 10 |
| Escherichia coli ECOR38 | 0.95 | HEPCGN_12310 | metF | methylenetetrahydrofolate reductase | 0.89 | HEPCGN_09110 | thrB | homoserine kinase | low | > 87 |
| Escherichia coli ECRC102 | 0.95 | NIAGMN_11420 | metF | methylenetetrahydrofolate reductase | 0.89 | NIAGMN_08955 | thrB | homoserine kinase | — | — |
| Escherichia coli ECRC98 | 0.95 | JDDGAC_17290 | metF | methylenetetrahydrofolate reductase | 0.89 | JDDGAC_14700 | thrB | homoserine kinase | 0.92 | 29 |
| Escherichia fergusonii Becca | 0.94 | EFB2_04672 | | 5,10-methylenetetrahydrofolate reductase | 0.89 | EFB2_04040 | | Homoserine kinase | low | > 86 |
| Escherichia coli Nissle 1917 | 0.94 | ECOLIN_RS22760 | | methylenetetrahydrofolate reductase | 0.89 | ECOLIN_RS00015 | | homoserine kinase | low | > 55 |
| Pantoea sp. MT58 | 0.92 | IAI47_00890 | | methylenetetrahydrofolate reductase | 0.84 | IAI47_16210 | | homoserine kinase | 0.43 | 74 |
| Serratia liquefaciens MT49 | 0.92 | IAI46_24530 | | methylenetetrahydrofolate reductase | 0.84 | IAI46_03035 | | homoserine kinase | 0.84 | 5 |
| Dickeya dadantii 3937 | 0.91 | DDA3937_RS00960 | | methylenetetrahydrofolate reductase | 0.82 | DDA3937_RS18410 | | homoserine kinase | low | > 74 |
| Rahnella sp. WP5 | 0.91 | EX31_RS14205 | | methylenetetrahydrofolate reductase | 0.85 | EX31_RS03940 | | homoserine kinase | 0.93 | 5 |
| Pectobacterium carotovorum WPP14 | 0.90 | HER17_RS00950 | | methylenetetrahydrofolate reductase | 0.83 | HER17_RS02800 | | homoserine kinase | low | > 75 |
| Dickeya dianthicola 67-19 | 0.90 | HGI48_RS20415 | | methylenetetrahydrofolate reductase | 0.81 | HGI48_RS18340 | | homoserine kinase | low | > 71 |
| Dickeya dianthicola ME23 | 0.90 | DZA65_RS21460 | | methylenetetrahydrofolate reductase | 0.81 | DZA65_RS19480 | | homoserine kinase | 0.72 | 22 |
| Erwinia tracheiphila SCR3 | 0.87 | LU632_RS19630 | metF | methylenetetrahydrofolate reductase | 0.79 | LU632_RS02615 | thrB | homoserine kinase | low | > 74 |
| Vibrio cholerae E7946 ATCC 55056 | 0.78 | CSW01_13560 | | methylenetetrahydrofolate reductase | 0.74 | CSW01_11970 | | homoserine kinase | low | > 62 |
| Shewanella oneidensis MR-1 | 0.76 | SO4054 | metF | 5,10-methylenetetrahydrofolate reductase (NCBI ptt file) | 0.51 | SO3414 | thrB | homoserine kinase (NCBI ptt file) | 0.93 | 33 |
| Shewanella amazonensis SB2B | 0.76 | Sama_3169 | metF | 5,10-methylenetetrahydrofolate reductase (RefSeq) | 0.53 | Sama_0906 | | homoserine kinase (RefSeq) | 0.96 | 27 |
| Shewanella sp. ANA-3 | 0.76 | Shewana3_3612 | metF | 5,10-methylenetetrahydrofolate reductase (RefSeq) | 0.52 | Shewana3_1140 | | homoserine kinase (RefSeq) | 0.94 | 25 |
| Shewanella loihica PV-4 | 0.75 | Shew_0522 | metF | 5,10-methylenetetrahydrofolate reductase (RefSeq) | 0.53 | Shew_1080 | | homoserine kinase (RefSeq) | 0.92 | 41 |
| Alteromonas macleodii MIT1002 | 0.70 | MIT1002_03670 | | 5,10-methylenetetrahydrofolate reductase | 0.50 | MIT1002_03085 | | Homoserine kinase | low | > 70 |
| Xanthomonas campestris pv. campestris strain 8004 | 0.37 | Xcc-8004.4336.1 | | 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) | 0.16 | Xcc-8004.2956.1 | | Homoserine kinase (EC 2.7.1.39) | 0.66 | 34 |
| Rhodanobacter denitrificans MT42 | 0.37 | LRK55_RS11765 | | methylenetetrahydrofolate reductase [NAD(P)H] | 0.19 | LRK55_RS10000 | | homoserine kinase | — | — |
| Rhodanobacter denitrificans FW104-10B01 | 0.37 | LRK54_RS12030 | | methylenetetrahydrofolate reductase [NAD(P)H] | 0.19 | LRK54_RS10360 | | homoserine kinase | 0.58 | 44 |
| Rhodanobacter sp. FW510-T8 | 0.36 | OKGIIK_11830 | metF | methylenetetrahydrofolate reductase [NAD(P)H] | 0.18 | OKGIIK_13565 | thrB | homoserine kinase | low | > 52 |
| Dyella japonica UNC79MFTsu3.2 | 0.36 | ABZR86_RS11570 | | methylenetetrahydrofolate reductase [NAD(P)H] | 0.16 | ABZR86_RS15980 | | homoserine kinase (EC 2.7.1.39) (from data) | 0.92 | 56 |
| Lysobacter sp. OAE881 | 0.35 | ABIE51_RS16490 | | methylenetetrahydrofolate reductase [NAD(P)H] | 0.19 | ABIE51_RS17525 | | homoserine kinase | 0.97 | 15 |
| Mucilaginibacter yixingensis YX-36 DSM 26809 | 0.22 | ABZR88_RS20935 | | methylenetetrahydrofolate reductase [NAD(P)H] | 0.24 | ABZR88_RS18955 | | homoserine kinase | — | — |
| Echinicola vietnamensis KMM 6221, DSM 17526 | 0.21 | Echvi_3637 | | 5,10-methylenetetrahydrofolate reductase, prokaryotic form | 0.22 | Echvi_2001 | | homoserine kinase (EC 2.7.1.39) (from data) | 0.94 | 5 |
| Pedobacter sp. GW460-11-11-14-LB5 | 0.21 | CA265_RS23445 | | methylenetetrahydrofolate reductase [NAD(P)H] | 0.23 | CA265_RS23470 | | homoserine kinase (EC 2.7.1.39) (from data) | 0.97 | 8 |
Not shown: 60 genomes with orthologs for BWI76_RS00805 only; 3 genomes with orthologs for BWI76_RS04250 only