Conservation of cofitness between BWI76_RS04675 and BWI76_RS04245 in Klebsiella michiganensis M5al

41 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Klebsiella michiganensis M5al 1.0 BWI76_RS04675 3-isopropylmalate dehydrogenase 1.0 BWI76_RS04245 bifunctional aspartate kinase/homoserine dehydrogenase I 0.93 8
Enterobacter asburiae PDN3 0.95 EX28DRAFT_3669 3-isopropylmalate dehydrogenase 0.89 EX28DRAFT_3614 aspartate kinase (EC 2.7.2.4) 0.67 46
Enterobacter sp. TBS_079 0.95 MPMX20_00768 3-isopropylmalate dehydrogenase 0.90 MPMX20_00710 Bifunctional aspartokinase/homoserine dehydrogenase 1 0.93 14
Escherichia coli Nissle 1917 0.93 ECOLIN_RS00395 3-isopropylmalate dehydrogenase 0.92 ECOLIN_RS00010 bifunctional aspartate kinase/homoserine dehydrogenase I low > 55
Escherichia coli ECRC98 0.93 JDDGAC_14315 leuB 3-isopropylmalate dehydrogenase 0.92 JDDGAC_14705 thrA bifunctional aspartate kinase/homoserine dehydrogenase I 0.95 19
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.93 GFF165 3-isopropylmalate dehydrogenase (EC 1.1.1.85) 0.92 GFF1078 Aspartokinase (EC 2.7.2.4) / Homoserine dehydrogenase (EC 1.1.1.3) low > 78
Escherichia coli ECRC101 0.93 MCAODC_01235 leuB 3-isopropylmalate dehydrogenase 0.92 MCAODC_01625 thrA bifunctional aspartate kinase/homoserine dehydrogenase I 0.79 58
Escherichia coli ECRC99 0.93 KEDOAH_17435 leuB 3-isopropylmalate dehydrogenase 0.92 KEDOAH_17045 thrA bifunctional aspartate kinase/homoserine dehydrogenase I — —
Escherichia fergusonii Becca 0.93 EFB2_03972 3-isopropylmalate dehydrogenase 0.92 EFB2_04041 Bifunctional aspartokinase/homoserine dehydrogenase 1 low > 86
Escherichia coli ECOR38 0.93 HEPCGN_08700 leuB 3-isopropylmalate dehydrogenase 0.92 HEPCGN_09115 thrA bifunctional aspartate kinase/homoserine dehydrogenase I 0.94 36
Escherichia coli ECRC102 0.93 NIAGMN_08570 leuB 3-isopropylmalate dehydrogenase 0.92 NIAGMN_08960 thrA bifunctional aspartate kinase/homoserine dehydrogenase I — —
Escherichia coli ECRC100 0.93 OKFHMN_10720 leuB 3-isopropylmalate dehydrogenase 0.92 OKFHMN_11110 thrA bifunctional aspartate kinase/homoserine dehydrogenase I 0.98 22
Escherichia coli BW25113 0.93 b0073 leuB 3-isopropylmalate dehydrogenase (VIMSS) 0.92 b0002 thrA bifunctional aspartokinase I/homeserine dehydrogenase I (NCBI) 0.91 35
Escherichia coli ECRC62 0.93 BNILDI_08545 leuA 2-isopropylmalate synthase 0.92 BNILDI_08160 thrA bifunctional aspartate kinase/homoserine dehydrogenase I 0.98 11
Escherichia coli ECOR27 0.93 NOLOHH_03065 leuA 2-isopropylmalate synthase 0.92 NOLOHH_03440 thrA bifunctional aspartate kinase/homoserine dehydrogenase I 0.93 30
Escherichia coli HS(pFamp)R (ATCC 700891) 0.93 OHPLBJKB_03584 3-isopropylmalate dehydrogenase 0.92 OHPLBJKB_03658 Bifunctional aspartokinase/homoserine dehydrogenase 1 low > 73
Escherichia coli BL21 0.93 ECD_00075 3-isopropylmalate dehydrogenase, NAD(+)-dependent 0.92 ECD_00002 Bifunctional aspartokinase/homoserine dehydrogenase 1 0.97 8
Dickeya dianthicola 67-19 0.89 HGI48_RS18060 3-isopropylmalate dehydrogenase 0.80 HGI48_RS18345 bifunctional aspartate kinase/homoserine dehydrogenase I 0.86 9
Dickeya dadantii 3937 0.89 DDA3937_RS18120 3-isopropylmalate dehydrogenase 0.80 DDA3937_RS18415 bifunctional aspartate kinase/homoserine dehydrogenase I 0.72 23
Dickeya dianthicola ME23 0.89 DZA65_RS19205 3-isopropylmalate dehydrogenase 0.80 DZA65_RS19485 bifunctional aspartate kinase/homoserine dehydrogenase I 0.85 14
Pectobacterium carotovorum WPP14 0.88 HER17_RS03080 3-isopropylmalate dehydrogenase 0.83 HER17_RS02795 bifunctional aspartate kinase/homoserine dehydrogenase I 0.92 50
Serratia liquefaciens MT49 0.87 IAI46_03350 3-isopropylmalate dehydrogenase 0.84 IAI46_03030 bifunctional aspartate kinase/homoserine dehydrogenase I 0.71 10
Rahnella sp. WP5 0.86 EX31_RS03685 3-isopropylmalate dehydrogenase 0.85 EX31_RS03945 bifunctional aspartate kinase/homoserine dehydrogenase I 0.97 23
Erwinia tracheiphila SCR3 0.82 LU632_RS02875 leuB 3-isopropylmalate dehydrogenase 0.83 LU632_RS02610 thrA bifunctional aspartate kinase/homoserine dehydrogenase I 0.85 12
Pantoea sp. MT58 0.82 IAI47_16005 3-isopropylmalate dehydrogenase 0.84 IAI47_16215 bifunctional aspartate kinase/homoserine dehydrogenase I 0.97 20
Vibrio cholerae E7946 ATCC 55056 0.77 CSW01_12600 3-isopropylmalate dehydrogenase 0.62 CSW01_11975 bifunctional aspartate kinase/homoserine dehydrogenase I low > 62
Shewanella sp. ANA-3 0.68 Shewana3_3760 3-isopropylmalate dehydrogenase (RefSeq) 0.56 Shewana3_1139 thrA bifunctional aspartokinase I/homeserine dehydrogenase I (RefSeq) 0.92 29
Shewanella loihica PV-4 0.68 Shew_3471 3-isopropylmalate dehydrogenase (RefSeq) 0.57 Shew_1079 thrA bifunctional aspartokinase I/homeserine dehydrogenase I (RefSeq) 0.98 19
Shewanella oneidensis MR-1 0.68 SO4235 leuB 3-isopropylmalate dehydrogenase (NCBI ptt file) 0.56 SO3415 thrA aspartokinase I/homoserine dehydrogenase, threonine-sensitive (NCBI ptt file) low > 76
Shewanella amazonensis SB2B 0.68 Sama_0336 3-isopropylmalate dehydrogenase (RefSeq) 0.53 Sama_0905 thrA bifunctional aspartokinase I/homeserine dehydrogenase I (RefSeq) 0.90 47
Alteromonas macleodii MIT1002 0.63 MIT1002_00948 3-isopropylmalate dehydrogenase 0.53 MIT1002_03086 Aspartokinase I/homoserine dehydrogenase I 0.97 27
Xanthomonas campestris pv. campestris strain 8004 0.48 Xcc-8004.1053.1 3-isopropylmalate dehydrogenase (EC 1.1.1.85) 0.33 Xcc-8004.2957.1 Aspartokinase (EC 2.7.2.4) / Homoserine dehydrogenase (EC 1.1.1.3) 0.75 43
Phocaeicola vulgatus CL09T03C04 0.43 HMPREF1058_RS14565 3-isopropylmalate dehydrogenase 0.32 HMPREF1058_RS14720 bifunctional aspartate kinase/homoserine dehydrogenase I 0.76 18
Phocaeicola dorei CL03T12C01 0.43 ABI39_RS10215 3-isopropylmalate dehydrogenase 0.32 ABI39_RS10430 bifunctional aspartate kinase/homoserine dehydrogenase I 0.86 7
Echinicola vietnamensis KMM 6221, DSM 17526 0.43 Echvi_2062 3-isopropylmalate dehydrogenase 0.34 Echvi_2000 aspartate kinase / homoserine dehydrogenase (EC 2.7.2.4; EC 1.1.1.3) (from data) — —
Pedobacter sp. GW460-11-11-14-LB5 0.43 CA265_RS15850 3-isopropylmalate dehydrogenase 0.32 CA265_RS23475 aspartate kinase; homoserine dehydrogenase (EC 2.7.2.4; EC 1.1.1.3) (from data) 0.96 3
Mucilaginibacter yixingensis YX-36 DSM 26809 0.42 ABZR88_RS11605 3-isopropylmalate dehydrogenase 0.32 ABZR88_RS18950 bifunctional aspartate kinase/homoserine dehydrogenase I — —
Bacteroides thetaiotaomicron VPI-5482 0.42 BT1857 3-isopropylmalate dehydrogenase (NCBI ptt file) 0.28 BT2403 aspartate kinase / homoserine dehydrogenase (EC 2.7.2.4; EC 1.1.1.3) (from data) 0.93 3
Bacteroides ovatus ATCC 8483 0.42 BACOVA_04600 3-isopropylmalate dehydrogenase 0.28 BACOVA_03021 homoserine dehydrogenase 0.95 13
Parabacteroides merdae CL09T00C40 0.42 HMPREF1078_RS16640 3-isopropylmalate dehydrogenase 0.31 HMPREF1078_RS10385 bifunctional aspartate kinase/homoserine dehydrogenase I 0.93 39
Lysobacter sp. OAE881 0.41 ABIE51_RS17585 3-isopropylmalate dehydrogenase 0.30 ABIE51_RS17520 bifunctional aspartate kinase/homoserine dehydrogenase I 0.98 6
Bacteroides stercoris CC31F 0.41 HMPREF1181_RS14125 3-isopropylmalate dehydrogenase 0.28 HMPREF1181_RS00060 bifunctional aspartate kinase/homoserine dehydrogenase I 0.91 8

Not shown: 57 genomes with orthologs for BWI76_RS04675 only; 0 genomes with orthologs for BWI76_RS04245 only