Conservation of cofitness between BWI76_RS00805 and BWI76_RS04245 in Klebsiella michiganensis M5al

41 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Klebsiella michiganensis M5al 1.0 BWI76_RS00805 5,10-methylenetetrahydrofolate reductase 1.0 BWI76_RS04245 bifunctional aspartate kinase/homoserine dehydrogenase I 0.92 2
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.96 GFF2329 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) 0.92 GFF1078 Aspartokinase (EC 2.7.2.4) / Homoserine dehydrogenase (EC 1.1.1.3) low > 78
Enterobacter asburiae PDN3 0.95 EX28DRAFT_4413 5,10-methylenetetrahydrofolate reductase, prokaryotic form 0.89 EX28DRAFT_3614 aspartate kinase (EC 2.7.2.4) low > 76
Escherichia coli ECOR27 0.95 NOLOHH_05810 metF methylenetetrahydrofolate reductase 0.92 NOLOHH_03440 thrA bifunctional aspartate kinase/homoserine dehydrogenase I 0.93 44
Escherichia coli ECRC62 0.95 BNILDI_05725 metF methylenetetrahydrofolate reductase 0.92 BNILDI_08160 thrA bifunctional aspartate kinase/homoserine dehydrogenase I 0.98 13
Enterobacter sp. TBS_079 0.95 MPMX20_04529 5,10-methylenetetrahydrofolate reductase 0.90 MPMX20_00710 Bifunctional aspartokinase/homoserine dehydrogenase 1 0.75 11
Escherichia coli HS(pFamp)R (ATCC 700891) 0.95 OHPLBJKB_04109 5,10-methylenetetrahydrofolate reductase 0.92 OHPLBJKB_03658 Bifunctional aspartokinase/homoserine dehydrogenase 1 low > 73
Escherichia coli BL21 0.95 ECD_03827 5,10-methylenetetrahydrofolate reductase 0.92 ECD_00002 Bifunctional aspartokinase/homoserine dehydrogenase 1 0.97 2
Escherichia coli BW25113 0.95 b3941 metF 5,10-methylenetetrahydrofolate reductase (NCBI) 0.92 b0002 thrA bifunctional aspartokinase I/homeserine dehydrogenase I (NCBI) 0.94 28
Escherichia coli ECRC101 0.95 MCAODC_04165 metF methylenetetrahydrofolate reductase 0.92 MCAODC_01625 thrA bifunctional aspartate kinase/homoserine dehydrogenase I 0.82 57
Escherichia coli ECOR38 0.95 HEPCGN_12310 metF methylenetetrahydrofolate reductase 0.92 HEPCGN_09115 thrA bifunctional aspartate kinase/homoserine dehydrogenase I 0.90 50
Escherichia coli ECRC98 0.95 JDDGAC_17290 metF methylenetetrahydrofolate reductase 0.92 JDDGAC_14705 thrA bifunctional aspartate kinase/homoserine dehydrogenase I 0.94 23
Escherichia coli ECRC99 0.95 KEDOAH_14495 metF methylenetetrahydrofolate reductase 0.92 KEDOAH_17045 thrA bifunctional aspartate kinase/homoserine dehydrogenase I
Escherichia coli ECRC102 0.95 NIAGMN_11420 metF methylenetetrahydrofolate reductase 0.92 NIAGMN_08960 thrA bifunctional aspartate kinase/homoserine dehydrogenase I
Escherichia coli ECRC100 0.95 OKFHMN_13665 metF methylenetetrahydrofolate reductase 0.92 OKFHMN_11110 thrA bifunctional aspartate kinase/homoserine dehydrogenase I 0.98 19
Escherichia fergusonii Becca 0.94 EFB2_04672 5,10-methylenetetrahydrofolate reductase 0.92 EFB2_04041 Bifunctional aspartokinase/homoserine dehydrogenase 1 low > 86
Escherichia coli Nissle 1917 0.94 ECOLIN_RS22760 methylenetetrahydrofolate reductase 0.92 ECOLIN_RS00010 bifunctional aspartate kinase/homoserine dehydrogenase I low > 55
Pantoea sp. MT58 0.92 IAI47_00890 methylenetetrahydrofolate reductase 0.84 IAI47_16215 bifunctional aspartate kinase/homoserine dehydrogenase I low > 76
Serratia liquefaciens MT49 0.92 IAI46_24530 methylenetetrahydrofolate reductase 0.84 IAI46_03030 bifunctional aspartate kinase/homoserine dehydrogenase I 0.79 14
Dickeya dadantii 3937 0.91 DDA3937_RS00960 methylenetetrahydrofolate reductase 0.80 DDA3937_RS18415 bifunctional aspartate kinase/homoserine dehydrogenase I 0.37 59
Rahnella sp. WP5 0.91 EX31_RS14205 methylenetetrahydrofolate reductase 0.85 EX31_RS03945 bifunctional aspartate kinase/homoserine dehydrogenase I 0.94 2
Pectobacterium carotovorum WPP14 0.90 HER17_RS00950 methylenetetrahydrofolate reductase 0.83 HER17_RS02795 bifunctional aspartate kinase/homoserine dehydrogenase I low > 75
Dickeya dianthicola 67-19 0.90 HGI48_RS20415 methylenetetrahydrofolate reductase 0.80 HGI48_RS18345 bifunctional aspartate kinase/homoserine dehydrogenase I 0.46 52
Dickeya dianthicola ME23 0.90 DZA65_RS21460 methylenetetrahydrofolate reductase 0.80 DZA65_RS19485 bifunctional aspartate kinase/homoserine dehydrogenase I 0.74 15
Erwinia tracheiphila SCR3 0.87 LU632_RS19630 metF methylenetetrahydrofolate reductase 0.83 LU632_RS02610 thrA bifunctional aspartate kinase/homoserine dehydrogenase I low > 74
Vibrio cholerae E7946 ATCC 55056 0.78 CSW01_13560 methylenetetrahydrofolate reductase 0.62 CSW01_11975 bifunctional aspartate kinase/homoserine dehydrogenase I low > 62
Shewanella oneidensis MR-1 0.76 SO4054 metF 5,10-methylenetetrahydrofolate reductase (NCBI ptt file) 0.56 SO3415 thrA aspartokinase I/homoserine dehydrogenase, threonine-sensitive (NCBI ptt file) low > 76
Shewanella amazonensis SB2B 0.76 Sama_3169 metF 5,10-methylenetetrahydrofolate reductase (RefSeq) 0.53 Sama_0905 thrA bifunctional aspartokinase I/homeserine dehydrogenase I (RefSeq) 0.93 44
Shewanella sp. ANA-3 0.76 Shewana3_3612 metF 5,10-methylenetetrahydrofolate reductase (RefSeq) 0.56 Shewana3_1139 thrA bifunctional aspartokinase I/homeserine dehydrogenase I (RefSeq) 0.93 35
Shewanella loihica PV-4 0.75 Shew_0522 metF 5,10-methylenetetrahydrofolate reductase (RefSeq) 0.57 Shew_1079 thrA bifunctional aspartokinase I/homeserine dehydrogenase I (RefSeq) 0.99 10
Alteromonas macleodii MIT1002 0.70 MIT1002_03670 5,10-methylenetetrahydrofolate reductase 0.53 MIT1002_03086 Aspartokinase I/homoserine dehydrogenase I low > 70
Xanthomonas campestris pv. campestris strain 8004 0.37 Xcc-8004.4336.1 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) 0.33 Xcc-8004.2957.1 Aspartokinase (EC 2.7.2.4) / Homoserine dehydrogenase (EC 1.1.1.3) low > 74
Lysobacter sp. OAE881 0.35 ABIE51_RS16490 methylenetetrahydrofolate reductase [NAD(P)H] 0.30 ABIE51_RS17520 bifunctional aspartate kinase/homoserine dehydrogenase I 0.98 12
Mucilaginibacter yixingensis YX-36 DSM 26809 0.22 ABZR88_RS20935 methylenetetrahydrofolate reductase [NAD(P)H] 0.32 ABZR88_RS18950 bifunctional aspartate kinase/homoserine dehydrogenase I
Parabacteroides merdae CL09T00C40 0.21 HMPREF1078_RS07860 methylenetetrahydrofolate reductase [NAD(P)H] 0.31 HMPREF1078_RS10385 bifunctional aspartate kinase/homoserine dehydrogenase I low > 61
Echinicola vietnamensis KMM 6221, DSM 17526 0.21 Echvi_3637 5,10-methylenetetrahydrofolate reductase, prokaryotic form 0.34 Echvi_2000 aspartate kinase / homoserine dehydrogenase (EC 2.7.2.4; EC 1.1.1.3) (from data) 0.94 3
Pedobacter sp. GW460-11-11-14-LB5 0.21 CA265_RS23445 methylenetetrahydrofolate reductase [NAD(P)H] 0.32 CA265_RS23475 aspartate kinase; homoserine dehydrogenase (EC 2.7.2.4; EC 1.1.1.3) (from data) 0.98 2
Bacteroides thetaiotaomicron VPI-5482 0.20 BT3821 5,10-methylenetetrahydrofolate reductase (NCBI ptt file) 0.28 BT2403 aspartate kinase / homoserine dehydrogenase (EC 2.7.2.4; EC 1.1.1.3) (from data) low > 81
Phocaeicola dorei CL03T12C01 0.19 ABI39_RS15570 methylenetetrahydrofolate reductase [NAD(P)H] 0.32 ABI39_RS10430 bifunctional aspartate kinase/homoserine dehydrogenase I low > 72
Phocaeicola vulgatus CL09T03C04 0.19 HMPREF1058_RS01490 methylenetetrahydrofolate reductase [NAD(P)H] 0.32 HMPREF1058_RS14720 bifunctional aspartate kinase/homoserine dehydrogenase I low > 67
Bacteroides stercoris CC31F 0.18 HMPREF1181_RS00120 methylenetetrahydrofolate reductase [NAD(P)H] 0.28 HMPREF1181_RS00060 bifunctional aspartate kinase/homoserine dehydrogenase I low > 56
Bacteroides ovatus ATCC 8483 0.16 BACOVA_03666 methylenetetrahydrofolate reductase (NAD(P)H) 0.28 BACOVA_03021 homoserine dehydrogenase low > 94

Not shown: 58 genomes with orthologs for BWI76_RS00805 only; 0 genomes with orthologs for BWI76_RS04245 only