Conservation of cofitness between ABZR87_RS18635 and ABZR87_RS19030 in Ralstonia sp. UNC404CL21Col

41 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Ralstonia sp. UNC404CL21Col 1.0 ABZR87_RS18635 multidrug transporter subunit MdtD 1.0 ABZR87_RS19030 MdtA/MuxA family multidrug efflux RND transporter periplasmic adaptor subunit 0.42 11
Ralstonia solanacearum UW163 0.78 UW163_RS21465 MFS transporter 0.73 UW163_RS21005 multidrug transporter subunit MdtA — —
Ralstonia solanacearum IBSBF1503 0.78 RALBFv3_RS17685 MFS transporter 0.73 RALBFv3_RS18125 multidrug transporter subunit MdtA low > 76
Ralstonia solanacearum PSI07 0.78 RPSI07_RS05895 MFS transporter 0.70 RPSI07_RS05510 multidrug transporter subunit MdtA low > 81
Ralstonia solanacearum GMI1000 0.75 RS_RS23315 MFS transporter 0.70 RS_RS22910 multidrug transporter subunit MdtA low > 80
Paraburkholderia sabiae LMG 24235 0.61 QEN71_RS02875 multidrug transporter subunit MdtD 0.43 QEN71_RS23300 MdtA/MuxA family multidrug efflux RND transporter periplasmic adaptor subunit low > 153
Paraburkholderia bryophila 376MFSha3.1 0.61 H281DRAFT_04102 drug resistance transporter, EmrB/QacA subfamily 0.45 H281DRAFT_06493 membrane fusion protein, multidrug efflux system low > 103
Cupriavidus basilensis FW507-4G11 0.60 RR42_RS32075 EmrB/QacA subfamily drug resistance transporter 0.47 RR42_RS03315 RND transporter MFP subunit low > 128
Variovorax sp. OAS795 0.60 ABID97_RS24975 multidrug transporter subunit MdtD 0.32 ABID97_RS20860 efflux RND transporter periplasmic adaptor subunit low > 91
Variovorax sp. SCN45 0.57 GFF2063 Uncharacterized MFS-type transporter 0.34 GFF6660 Multidrug efflux system MdtABC-TolC, membrane fusion component MdtA low > 127
Pseudomonas fluorescens FW300-N2E2 0.55 Pf6N2E2_4674 Permeases of the major facilitator superfamily 0.41 Pf6N2E2_1273 Probable RND efflux membrane fusion protein low > 103
Pseudomonas fluorescens GW456-L13 0.54 PfGW456L13_1079 Permeases of the major facilitator superfamily 0.40 PfGW456L13_3267 RND transporter, membrane fusion protein low > 87
Pseudomonas sp. RS175 0.54 PFR28_04171 putative transport protein HsrA 0.42 PFR28_02195 Multidrug resistance protein MdtA low > 88
Pseudomonas fluorescens FW300-N1B4 0.54 Pf1N1B4_2413 Permeases of the major facilitator superfamily 0.40 Pf1N1B4_4664 RND transporter, membrane fusion protein — —
Pseudomonas fluorescens FW300-N2E3 0.53 AO353_07845 EmrB/QacA subfamily drug resistance transporter 0.40 AO353_22890 secretion protein HlyD low > 101
Pseudomonas stutzeri RCH2 0.51 Psest_0847 drug resistance transporter, EmrB/QacA subfamily 0.40 Psest_2138 RND family efflux transporter, MFP subunit low > 67
Pseudomonas fluorescens SBW25 0.49 PFLU_RS28015 DHA2 family efflux MFS transporter permease subunit 0.42 PFLU_RS13425 MdtA/MuxA family multidrug efflux RND transporter periplasmic adaptor subunit low > 109
Pseudomonas fluorescens SBW25-INTG 0.49 PFLU_RS28015 DHA2 family efflux MFS transporter permease subunit 0.42 PFLU_RS13425 MdtA/MuxA family multidrug efflux RND transporter periplasmic adaptor subunit low > 109
Pseudomonas simiae WCS417 0.48 PS417_26365 EmrB/QacA subfamily drug resistance transporter 0.42 PS417_12740 secretion protein HlyD low > 88
Rahnella sp. WP5 0.44 EX31_RS20305 DHA2 family efflux MFS transporter permease subunit 0.36 EX31_RS13385 MdtA/MuxA family multidrug efflux RND transporter periplasmic adaptor subunit low > 89
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.44 GFF3852 Multidrug transporter MdtD 0.37 GFF3855 Multidrug transporter MdtA low > 78
Enterobacter asburiae PDN3 0.44 EX28DRAFT_0481 Arabinose efflux permease 0.40 EX28DRAFT_0484 RND family efflux transporter, MFP subunit low > 76
Escherichia coli ECOR38 0.44 HEPCGN_13430 hsrA putative transport protein HsrA 0.38 HEPCGN_02890 mdtA multidrug efflux RND transporter subunit MdtA low > 87
Escherichia coli HS(pFamp)R (ATCC 700891) 0.44 OHPLBJKB_04296 putative transport protein HsrA 0.38 OHPLBJKB_01630 Multidrug resistance protein MdtA low > 73
Escherichia coli ECRC100 0.44 OKFHMN_14720 hsrA putative transport protein HsrA 0.38 OKFHMN_24200 mdtA multidrug efflux RND transporter subunit MdtA low > 80
Escherichia coli BW25113 0.44 b3754 hsrA predicted multidrug or homocysteine efflux system (NCBI) 0.38 b2074 b2074 putative membrane protein (VIMSS) low > 76
Escherichia coli Nissle 1917 0.44 ECOLIN_RS21590 multidrug transporter subunit MdtD 0.38 ECOLIN_RS12195 multidrug efflux RND transporter subunit MdtA low > 55
Escherichia coli ECRC102 0.44 NIAGMN_12475 hsrA putative transport protein HsrA 0.38 NIAGMN_22145 mdtA multidrug efflux RND transporter subunit MdtA — —
Escherichia fergusonii Becca 0.44 EFB2_04879 putative transport protein HsrA 0.37 EFB2_01781 Multidrug resistance protein MdtA low > 86
Escherichia coli ECRC101 0.44 MCAODC_05225 hsrA putative transport protein HsrA 0.38 MCAODC_20740 mdtA multidrug efflux RND transporter subunit MdtA low > 87
Escherichia coli ECRC98 0.44 JDDGAC_18340 hsrA putative transport protein HsrA 0.38 JDDGAC_28310 mdtA multidrug efflux RND transporter subunit MdtA low > 86
Escherichia coli ECRC99 0.44 KEDOAH_13430 hsrA putative transport protein HsrA 0.38 KEDOAH_03950 mdtA multidrug efflux RND transporter subunit MdtA — —
Escherichia coli BL21 0.44 ECD_03640 putative multidrug or homocysteine efflux system 0.38 ECD_01979 multidrug efflux system, subunit A low > 61
Escherichia coli ECRC62 0.43 BNILDI_04670 hsrA putative transport protein HsrA 0.38 BNILDI_14460 mdtA multidrug efflux RND transporter subunit MdtA low > 75
Escherichia coli ECOR27 0.43 NOLOHH_06855 hsrA putative transport protein HsrA 0.37 NOLOHH_15545 mdtA multidrug efflux RND transporter subunit MdtA low > 75
Klebsiella michiganensis M5al 0.43 BWI76_RS19265 multidrug transporter subunit MdtD 0.37 BWI76_RS19250 multidrug transporter subunit MdtA low > 92
Enterobacter sp. TBS_079 0.43 MPMX20_03063 Putative multidrug resistance protein MdtD 0.39 MPMX20_03060 Multidrug resistance protein MdtA low > 85
Dickeya dianthicola ME23 0.42 DZA65_RS16175 MFS transporter 0.35 DZA65_RS16160 MdtA/MuxA family multidrug efflux RND transporter periplasmic adaptor subunit low > 75
Dickeya dianthicola 67-19 0.42 HGI48_RS15355 multidrug transporter subunit MdtD 0.37 HGI48_RS15340 MdtA/MuxA family multidrug efflux RND transporter periplasmic adaptor subunit low > 71
Dyella japonica UNC79MFTsu3.2 0.34 ABZR86_RS01865 MFS transporter 0.27 ABZR86_RS16315 efflux RND transporter periplasmic adaptor subunit low > 74
Castellaniella sp019104865 MT123 0.31 ABCV34_RS14570 DHA2 family efflux MFS transporter permease subunit 0.33 ABCV34_RS14615 efflux RND transporter periplasmic adaptor subunit low > 48
Rhodanobacter sp. FW510-T8 0.30 OKGIIK_07515 MFS transporter 0.27 OKGIIK_16100 HlyD-D23 domain-containing protein low > 52

Not shown: 24 genomes with orthologs for ABZR87_RS18635 only; 2 genomes with orthologs for ABZR87_RS19030 only