| Organism | Ratio1 | Gene1 | Name1 | Description1 | Ratio2 | Gene2 | Name2 | Description2 | Cofit | Rank |
|---|
| Bacteroides thetaiotaomicron VPI-5482 | 1.0 | BT1607 | | methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase (NCBI ptt file) | 1.0 | BT4211 | | putative phosphoribosylformylglycinamidine cyclo-ligase (NCBI ptt file) | 0.81 | 5 |
| Bacteroides stercoris CC31F | 0.97 | HMPREF1181_RS11305 | | bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD | 0.93 | HMPREF1181_RS06340 | | phosphoribosylformylglycinamidine cyclo-ligase | 0.83 | 8 |
| Bacteroides ovatus ATCC 8483 | 0.97 | BACOVA_04344 | | tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain protein | 0.97 | BACOVA_05058 | | hypothetical protein | 0.90 | 24 |
| Phocaeicola vulgatus CL09T03C04 | 0.96 | HMPREF1058_RS15075 | | bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD | 0.93 | HMPREF1058_RS08025 | | phosphoribosylformylglycinamidine cyclo-ligase | 0.76 | 7 |
| Phocaeicola dorei CL03T12C01 | 0.96 | ABI39_RS10870 | | bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD | 0.94 | ABI39_RS00475 | | phosphoribosylformylglycinamidine cyclo-ligase | 0.81 | 9 |
| Parabacteroides merdae CL09T00C40 | 0.84 | HMPREF1078_RS14700 | | bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD | 0.91 | HMPREF1078_RS13965 | | AIR synthase-related protein | low | > 61 |
| Pontibacter actiniarum KMM 6156, DSM 19842 | 0.68 | CA264_07145 | | bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/5,10-methylene-tetrahydrofolate cyclohydrolase | 0.78 | CA264_17695 | | phosphoribosylformylglycinamidine cyclo-ligase | — | — |
| Pedobacter sp. GW460-11-11-14-LB5 | 0.65 | CA265_RS08950 | | bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/5,10-methylene-tetrahydrofolate cyclohydrolase | 0.76 | CA265_RS05175 | | phosphoribosylformylglycinamidine cyclo-ligase | — | — |
| Echinicola vietnamensis KMM 6221, DSM 17526 | 0.65 | Echvi_4643 | | 5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase | 0.76 | Echvi_0734 | | Phosphoribosylaminoimidazole (AIR) synthetase | — | — |
| Mucilaginibacter yixingensis YX-36 DSM 26809 | 0.64 | ABZR88_RS09400 | | bifunctional 5,10-methylenetetrahydrofolate dehydrogenase/5,10-methenyltetrahydrofolate cyclohydrolase | 0.79 | ABZR88_RS04080 | | AIR synthase related protein | — | — |
| Desulfovibrio vulgaris Hildenborough JW710 | 0.46 | DVU0323 | folD | methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase (TIGR) | 0.10 | DVU1406 | purM | phosphoribosylformylglycinamidine cyclo-ligase (TIGR) | — | — |
| Desulfovibrio vulgaris Miyazaki F | 0.44 | DvMF_1809 | | Methenyltetrahydrofolate cyclohydrolase (RefSeq) | 0.10 | DvMF_0202 | | phosphoribosylaminoimidazole synthetase (RefSeq) | — | — |
| Kangiella aquimarina DSM 16071 | 0.44 | B158DRAFT_1028 | | methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9)/5,10-methylenetetrahydrofolate dehydrogenase (NADP+) (EC 1.5.1.5) | 0.08 | B158DRAFT_2385 | | phosphoribosylformylglycinamidine cyclo-ligase (EC 6.3.3.1) | — | — |
| Erwinia tracheiphila SCR3 | 0.44 | LU632_RS15195 | folD | bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD | 0.09 | LU632_RS08275 | purM | phosphoribosylformylglycinamidine cyclo-ligase | — | — |
| Dickeya dianthicola ME23 | 0.43 | DZA65_RS15960 | | bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD | 0.09 | DZA65_RS06420 | | phosphoribosylformylglycinamidine cyclo-ligase | — | — |
| Dickeya dianthicola 67-19 | 0.43 | HGI48_RS15155 | | bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD | 0.09 | HGI48_RS06070 | | phosphoribosylformylglycinamidine cyclo-ligase | — | — |
| Rahnella sp. WP5 | 0.43 | EX31_RS22835 | | bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD | 0.10 | EX31_RS22695 | | phosphoribosylformylglycinamidine cyclo-ligase | — | — |
| Dickeya dadantii 3937 | 0.43 | DDA3937_RS15075 | | bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD | 0.08 | DDA3937_RS06025 | | phosphoribosylformylglycinamidine cyclo-ligase | — | — |
| Alteromonas macleodii MIT1002 | 0.43 | MIT1002_02770 | | hypothetical protein | 0.07 | MIT1002_02219 | | Phosphoribosylformylglycinamidine cyclo-ligase | — | — |
| Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 | 0.43 | GFF4447 | | Methylenetetrahydrofolate dehydrogenase (NADP+) (EC 1.5.1.5) / Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9) | 0.09 | GFF2169 | | Phosphoribosylformylglycinamidine cyclo-ligase (EC 6.3.3.1) | — | — |
| Pectobacterium carotovorum WPP14 | 0.42 | HER17_RS06505 | | bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD | 0.09 | HER17_RS15465 | | phosphoribosylformylglycinamidine cyclo-ligase | — | — |
| Pantoea sp. MT58 | 0.42 | IAI47_14320 | | bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD | 0.10 | IAI47_05180 | | phosphoribosylformylglycinamidine cyclo-ligase | — | — |
| Escherichia coli HS(pFamp)R (ATCC 700891) | 0.41 | OHPLBJKB_03152 | | Bifunctional protein FolD protein | 0.08 | OHPLBJKB_01227 | | Phosphoribosylformylglycinamidine cyclo-ligase | — | — |
| Escherichia coli ECRC99 | 0.41 | KEDOAH_20165 | | Bifunctional protein FolD | 0.08 | KEDOAH_06410 | purM | Phosphoribosylformylglycinamidine cyclo-ligase | — | — |
| Escherichia fergusonii Becca | 0.41 | EFB2_03532 | | Bifunctional protein FolD protein | 0.09 | EFB2_01399 | | Phosphoribosylformylglycinamidine cyclo-ligase | — | — |
| Escherichia coli ECRC102 | 0.41 | NIAGMN_05860 | | Bifunctional protein FolD | 0.08 | NIAGMN_19580 | purM | Phosphoribosylformylglycinamidine cyclo-ligase | — | — |
| Escherichia coli BL21 | 0.41 | ECD_00479 | | bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase | 0.08 | ECD_02391 | | phosphoribosylaminoimidazole synthetase | — | — |
| Klebsiella michiganensis M5al | 0.41 | BWI76_RS07100 | | bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase | 0.09 | BWI76_RS20965 | | phosphoribosylformylglycinamidine cyclo-ligase | — | — |
| Escherichia coli BW25113 | 0.41 | b0529 | folD | bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase (NCBI) | 0.08 | b2499 | purM | phosphoribosylaminoimidazole synthetase (NCBI) | — | — |
| Escherichia coli ECRC62 | 0.41 | BNILDI_22225 | | bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD | 0.08 | BNILDI_12270 | purM | Phosphoribosylformylglycinamidine cyclo-ligase | — | — |
| Escherichia coli ECRC98 | 0.41 | JDDGAC_11455 | | Bifunctional protein FolD | 0.08 | JDDGAC_25755 | purM | Phosphoribosylformylglycinamidine cyclo-ligase | — | — |
| Escherichia coli ECRC101 | 0.41 | OKFHMN_07805 | | Bifunctional protein FolD | 0.08 | OKFHMN_21810 | purM | Phosphoribosylformylglycinamidine cyclo-ligase | — | — |
| Escherichia coli Nissle 1917 | 0.41 | ECOLIN_RS03065 | | bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD | 0.08 | ECOLIN_RS14190 | | phosphoribosylformylglycinamidine cyclo-ligase | — | — |
| Escherichia coli ECOR27 | 0.41 | NOLOHH_00795 | | Bifunctional protein FolD | 0.08 | NOLOHH_13460 | purM | Phosphoribosylformylglycinamidine cyclo-ligase | — | — |
| Escherichia coli ECRC101 | 0.41 | MCAODC_27025 | | Bifunctional protein FolD | 0.08 | MCAODC_12340 | purM | Phosphoribosylformylglycinamidine cyclo-ligase | — | — |
| Escherichia coli ECOR38 | 0.41 | HEPCGN_06445 | | Bifunctional protein FolD | 0.08 | HEPCGN_20975 | purM | Phosphoribosylformylglycinamidine cyclo-ligase | — | — |
| Serratia liquefaciens MT49 | 0.41 | IAI46_05400 | | bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD | 0.08 | IAI46_18885 | | phosphoribosylformylglycinamidine cyclo-ligase | — | — |
| Enterobacter asburiae PDN3 | 0.41 | EX28DRAFT_2449 | | 5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase | 0.09 | EX28DRAFT_0168 | | phosphoribosylformylglycinamidine cyclo-ligase (EC 6.3.3.1) | — | — |
| Enterobacter sp. TBS_079 | 0.41 | MPMX20_01107 | | Bifunctional protein FolD protein | 0.09 | MPMX20_03354 | | Phosphoribosylformylglycinamidine cyclo-ligase | — | — |
| Pseudomonas sp. RS175 | 0.40 | PFR28_01223 | | Bifunctional protein FolD protein | 0.06 | PFR28_03217 | | Phosphoribosylformylglycinamidine cyclo-ligase | — | — |
| Pseudomonas simiae WCS417 | 0.40 | PS417_17265 | | methenyltetrahydrofolate cyclohydrolase | 0.07 | PS417_20120 | | phosphoribosylaminoimidazole synthetase | — | — |
| Pseudomonas fluorescens FW300-N1B4 | 0.40 | Pf1N1B4_3943 | | Methylenetetrahydrofolate dehydrogenase (NADP+) (EC 1.5.1.5) / Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9) | 0.07 | Pf1N1B4_3698 | | Phosphoribosylformylglycinamidine cyclo-ligase (EC 6.3.3.1) | — | — |
| Pseudomonas fluorescens SBW25-INTG | 0.40 | PFLU_RS19200 | | bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD | 0.07 | PFLU_RS22065 | | phosphoribosylformylglycinamidine cyclo-ligase | — | — |
| Pseudomonas fluorescens SBW25 | 0.40 | PFLU_RS19200 | | bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD | 0.07 | PFLU_RS22065 | | phosphoribosylformylglycinamidine cyclo-ligase | — | — |
| Rhodopseudomonas palustris CGA009 | 0.38 | TX73_002145 | | bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD | 0.08 | TX73_015785 | | phosphoribosylformylglycinamidine cyclo-ligase | — | — |
| Acinetobacter radioresistens SK82 | 0.38 | MPMX26_00777 | | Bifunctional protein FolD protein | 0.09 | MPMX26_02206 | | Phosphoribosylformylglycinamidine cyclo-ligase | — | — |
| Fusobacterium nucleatum SB010 | 0.37 | HUW76_09060 | | bifunctional 5,10-methylenetetrahydrofolate dehydrogenase/5,10-methenyltetrahydrofolate cyclohydrolase | 0.09 | HUW76_05175 | | phosphoribosylformylglycinamidine cyclo-ligase | — | — |
| Lysobacter sp. OAE881 | 0.36 | ABIE51_RS09470 | | bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD | 0.09 | ABIE51_RS15890 | | phosphoribosylformylglycinamidine cyclo-ligase | — | — |
| Bifidobacterium breve UCC2003 | 0.33 | BBR_RS14270 | | bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase | 0.10 | BBR_RS13375 | | phosphoribosylformylglycinamidine cyclo-ligase | — | — |
Not shown: 53 genomes with orthologs for BT1607 only; 0 genomes with orthologs for BT4211 only