Conservation of cofitness between b3846 and b2076 in Escherichia coli BW25113

46 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Escherichia coli BW25113 1.0 b3846 fadB fused 3-hydroxybutyryl-CoA epimerase/delta(3)-cis-delta(2)-trans-enoyl-CoA isomerase/enoyl-CoA hydratase/3-hydroxyacyl-CoA dehydrogenase (NCBI) 1.0 b2076 mdtC multidrug efflux system, subunit C (NCBI) 0.22 17
Escherichia coli ECOR27 1.00 NOLOHH_06375 fadB fatty acid oxidation complex subunit alpha FadB 1.00 NOLOHH_15535 mdtC multidrug efflux RND transporter permease subunit MdtC low > 57
Escherichia coli HS(pFamp)R (ATCC 700891) 1.00 OHPLBJKB_04207 Fatty acid oxidation complex subunit alpha 1.00 OHPLBJKB_01628 Multidrug resistance protein MdtC low > 73
Escherichia coli ECOR38 0.99 HEPCGN_12875 fadB fatty acid oxidation complex subunit alpha FadB 0.99 HEPCGN_02880 mdtC multidrug efflux RND transporter permease subunit MdtC low > 85
Escherichia coli BL21 0.99 ECD_03737 fused 3-hydroxybutyryl-CoA epimerase/delta(3)-cis-delta(2)-trans-enoyl-CoA isomerase/enoyl-CoA hydratase/3-hydroxyacyl-CoA dehydrogenase 1.00 ECD_01981 multidrug efflux system, subunit C low > 60
Escherichia coli ECRC62 0.99 BNILDI_05155 fadB fatty acid oxidation complex subunit alpha FadB 1.00 BNILDI_14450 mdtC multidrug efflux RND transporter permease subunit MdtC — —
Escherichia coli ECRC98 0.99 JDDGAC_17870 fadB fatty acid oxidation complex subunit alpha FadB 1.00 JDDGAC_28300 mdtC multidrug efflux RND transporter permease subunit MdtC — —
Escherichia coli ECRC101 0.99 MCAODC_04750 fadB fatty acid oxidation complex subunit alpha FadB 1.00 MCAODC_20750 mdtC multidrug efflux RND transporter permease subunit MdtC — —
Escherichia coli ECRC99 0.99 KEDOAH_13905 fadB fatty acid oxidation complex subunit alpha FadB 1.00 KEDOAH_03960 mdtC multidrug efflux RND transporter permease subunit MdtC — —
Escherichia coli ECRC102 0.99 NIAGMN_12000 fadB fatty acid oxidation complex subunit alpha FadB 1.00 NIAGMN_22135 mdtC multidrug efflux RND transporter permease subunit MdtC — —
Escherichia coli ECRC101 0.99 OKFHMN_14245 fadB fatty acid oxidation complex subunit alpha FadB 1.00 OKFHMN_24190 mdtC multidrug efflux RND transporter permease subunit MdtC — —
Escherichia fergusonii Becca 0.99 EFB2_04771 Fatty acid oxidation complex subunit alpha 0.99 EFB2_01779 Multidrug resistance protein MdtC low > 86
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.93 GFF273 Enoyl-CoA hydratase (EC 4.2.1.17) / Delta(3)-cis-delta(2)-trans-enoyl-CoA isomerase (EC 5.3.3.8) / 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35) / 3-hydroxybutyryl-CoA epimerase (EC 5.1.2.3) 0.90 GFF3853 Multidrug transporter MdtC low > 78
Klebsiella michiganensis M5al 0.92 BWI76_RS01365 multifunctional fatty acid oxidation complex subunit alpha 0.90 BWI76_RS19260 multidrug transporter subunit MdtC low > 92
Enterobacter sp. TBS_079 0.91 MPMX20_04436 Fatty acid oxidation complex subunit alpha 0.92 MPMX20_03062 Multidrug resistance protein MdtC low > 85
Enterobacter asburiae PDN3 0.91 EX28DRAFT_4510 fatty oxidation complex, alpha subunit FadB 0.92 EX28DRAFT_0482 Cation/multidrug efflux pump low > 76
Serratia liquefaciens MT49 0.77 IAI46_01130 fatty acid oxidation complex subunit alpha FadB 0.82 IAI46_18980 multidrug efflux RND transporter permease subunit MdtC low > 86
Pectobacterium carotovorum WPP14 0.76 HER17_RS20550 fatty acid oxidation complex subunit alpha FadB 0.79 HER17_RS06315 multidrug efflux RND transporter permease subunit MdtC low > 75
Rahnella sp. WP5 0.74 EX31_RS14565 fatty acid oxidation complex subunit alpha FadB 0.53 EX31_RS13375 MMPL family transporter low > 89
Pantoea sp. MT58 0.73 IAI47_18230 fatty acid oxidation complex subunit alpha FadB 0.79 IAI47_06865 multidrug efflux RND transporter permease subunit MdtC low > 76
Dickeya dadantii 3937 0.67 DDA3937_RS20250 fatty acid oxidation complex subunit alpha FadB 0.78 DDA3937_RS15270 multidrug efflux RND transporter permease subunit MdtC low > 74
Dickeya dianthicola 67-19 0.65 HGI48_RS00975 fatty acid oxidation complex subunit alpha FadB 0.78 HGI48_RS15350 multidrug efflux RND transporter permease subunit MdtC low > 71
Dickeya dianthicola ME23 0.65 DZA65_RS01035 fatty acid oxidation complex subunit alpha FadB 0.78 DZA65_RS16170 multidrug efflux RND transporter permease subunit MdtC low > 75
Pseudomonas putida KT2440 0.54 PP_2136 enoyl-CoA hydratase/3-hydroxyacyl-CoA dehydrogenase 0.52 PP_3583 multidrug efflux transport system - membrane subunit low > 96
Pseudomonas syringae pv. syringae B728a 0.54 Psyr_3290 3-hydroxyacyl-CoA dehydrogenase / short chain enoyl-CoA hydratase 0.54 Psyr_2484 Acriflavin resistance protein low > 86
Pseudomonas syringae pv. syringae B728a ΔmexB 0.54 Psyr_3290 3-hydroxyacyl-CoA dehydrogenase / short chain enoyl-CoA hydratase 0.54 Psyr_2484 Acriflavin resistance protein low > 86
Pseudomonas simiae WCS417 0.54 PS417_07575 multifunctional fatty acid oxidation complex subunit alpha 0.52 PS417_12750 acriflavine resistance protein B low > 88
Pseudomonas fluorescens SBW25 0.54 PFLU_RS07650 fatty acid oxidation complex subunit alpha FadB 0.53 PFLU_RS13435 MMPL family transporter low > 109
Pseudomonas fluorescens SBW25-INTG 0.54 PFLU_RS07650 fatty acid oxidation complex subunit alpha FadB 0.53 PFLU_RS13435 MMPL family transporter low > 109
Pseudomonas sp. RS175 0.54 PFR28_01110 Fatty acid oxidation complex subunit alpha 0.51 PFR28_02193 Multidrug resistance protein MdtC low > 88
Pseudomonas fluorescens FW300-N2C3 0.54 AO356_02330 multifunctional fatty acid oxidation complex subunit alpha 0.52 AO356_25880 acriflavine resistance protein B — —
Pseudomonas fluorescens FW300-N2E2 0.54 Pf6N2E2_2290 Enoyl-CoA hydratase (EC 4.2.1.17) / Delta(3)-cis-delta(2)-trans-enoyl-CoA isomerase (EC 5.3.3.8) / 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35) / 3-hydroxybutyryl-CoA epimerase (EC 5.1.2.3) 0.52 Pf6N2E2_1271 Acriflavin resistance plasma membrane protein — —
Pseudomonas fluorescens GW456-L13 0.54 PfGW456L13_4041 Enoyl-CoA hydratase (EC 4.2.1.17) / Delta(3)-cis-delta(2)-trans-enoyl-CoA isomerase (EC 5.3.3.8) / 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35) / 3-hydroxybutyryl-CoA epimerase (EC 5.1.2.3) 0.54 PfGW456L13_3265 Acriflavin resistance plasma membrane protein low > 87
Pseudomonas fluorescens FW300-N2E3 0.53 AO353_00510 multifunctional fatty acid oxidation complex subunit alpha 0.55 AO353_22900 acriflavine resistance protein B low > 101
Pseudomonas sp. S08-1 0.53 OH686_21925 fatty oxidation complex, alpha subunit FadB 0.55 OH686_00930 Multidrug efflux system MdtABC-TolC, inner-membrane proton/drug antiporter MdtC (RND type) low > 80
Pseudomonas stutzeri RCH2 0.53 Psest_2654 fatty oxidation complex, alpha subunit FadB 0.53 Psest_2140 Cation/multidrug efflux pump — —
Acinetobacter radioresistens SK82 0.50 MPMX26_00226 Fatty acid oxidation complex subunit alpha 0.23 MPMX26_02516 Multidrug resistance protein MdtC low > 36
Hydrogenophaga sp. GW460-11-11-14-LB1 0.35 GFF2109 Enoyl-CoA hydratase (EC 4.2.1.17) / Delta(3)-cis-delta(2)-trans-enoyl-CoA isomerase (EC 5.3.3.8) / 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35) / 3-hydroxybutyryl-CoA epimerase (EC 5.1.2.3) 0.46 GFF488 RND multidrug efflux transporter; Acriflavin resistance protein low > 90
Paraburkholderia bryophila 376MFSha3.1 0.24 H281DRAFT_00916 short chain enoyl-CoA hydratase /3-hydroxyacyl-CoA dehydrogenase 0.45 H281DRAFT_06491 multidrug efflux pump low > 103
Rhodopseudomonas palustris CGA009 0.23 TX73_019255 3-hydroxyacyl-CoA dehydrogenase NAD-binding domain-containing protein 0.49 TX73_018025 multidrug efflux RND transporter permease subunit low > 86
Burkholderia phytofirmans PsJN 0.23 BPHYT_RS09560 3-hydroxyacyl-CoA dehydrogenase 0.43 BPHYT_RS07780 nodulation protein low > 109
Paraburkholderia sabiae LMG 24235 0.23 QEN71_RS21890 3-hydroxyacyl-CoA dehydrogenase NAD-binding domain-containing protein 0.47 QEN71_RS29845 efflux RND transporter permease subunit low > 153
Ralstonia sp. UNC404CL21Col 0.23 ABZR87_RS12585 3-hydroxyacyl-CoA dehydrogenase NAD-binding domain-containing protein 0.62 ABZR87_RS19020 multidrug efflux RND transporter permease subunit low > 80
Ralstonia solanacearum GMI1000 0.22 RS_RS08885 3-hydroxyacyl-CoA dehydrogenase 0.63 RS_RS22920 nodulation protein low > 80
Ralstonia solanacearum PSI07 0.22 RPSI07_RS16345 3-hydroxyacyl-CoA dehydrogenase 0.63 RPSI07_RS05520 nodulation protein low > 81
Ralstonia solanacearum IBSBF1503 0.22 RALBFv3_RS01130 3-hydroxyacyl-CoA dehydrogenase 0.63 RALBFv3_RS18115 nodulation protein low > 76
Ralstonia solanacearum UW163 0.22 UW163_RS14440 3-hydroxyacyl-CoA dehydrogenase 0.63 UW163_RS21015 nodulation protein — —

Not shown: 11 genomes with orthologs for b3846 only; 14 genomes with orthologs for b2076 only