Conservation of cofitness between b1991 and b1622 in Escherichia coli BW25113

36 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Escherichia coli BW25113 1.0 b1991 cobT nicotinate-nucleotide--dimethylbenzimidazolephosphoribosyltransferase (NCBI) 1.0 b1622 malY bifunctional beta-cystathionase, PLP-dependent/ regulator of maltose regulon (NCBI) 0.16 19
Escherichia coli BL21 1.00 ECD_01900 nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase 0.99 ECD_01591 PLP-dependent beta-cystathionase and maltose regulon regulator low > 60
Escherichia fergusonii Becca 0.98 EFB2_01898 Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase 0.99 EFB2_02370 Protein MalY low > 86
Escherichia coli ECOR38 0.98 HEPCGN_03470 cobT nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase 0.99 HEPCGN_05965 malY bifunctional maltose regulon transcriptional repressor/cystathionine beta-lyase MalY low > 85
Escherichia coli Nissle 1917 0.98 ECOLIN_RS11620 nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase 0.99 ECOLIN_RS09050 bifunctional maltose regulon transcriptional repressor/cystathionine beta-lyase MalY — —
Escherichia coli HS(pFamp)R (ATCC 700891) 0.97 OHPLBJKB_01717 Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase 1.00 OHPLBJKB_02104 Protein MalY low > 73
Escherichia coli ECRC62 0.97 BNILDI_14875 cobT nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase 0.99 BNILDI_16890 malY bifunctional maltose regulon transcriptional repressor/cystathionine beta-lyase MalY — —
Escherichia coli ECOR27 0.97 NOLOHH_16045 cobT nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase 0.99 NOLOHH_18100 malY bifunctional maltose regulon transcriptional repressor/cystathionine beta-lyase MalY — —
Escherichia coli ECRC101 0.96 OKFHMN_25135 cobT nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase 1.00 OKFHMN_27585 malY bifunctional maltose regulon transcriptional repressor/cystathionine beta-lyase MalY — —
Escherichia coli ECRC101 0.96 MCAODC_20255 cobT nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase 1.00 MCAODC_17825 malY bifunctional maltose regulon transcriptional repressor/cystathionine beta-lyase MalY — —
Escherichia coli ECRC99 0.96 KEDOAH_02975 cobT nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase 1.00 KEDOAH_00520 malY bifunctional maltose regulon transcriptional repressor/cystathionine beta-lyase MalY — —
Escherichia coli ECRC98 0.96 JDDGAC_29265 cobT nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase 1.00 JDDGAC_02175 malY bifunctional maltose regulon transcriptional repressor/cystathionine beta-lyase MalY — —
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.78 GFF3969 Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase (EC 2.4.2.21) 0.26 GFF2547 Aspartate aminotransferase (EC 2.6.1.1) low > 78
Klebsiella michiganensis M5al 0.73 BWI76_RS23000 nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase 0.75 BWI76_RS16300 bifunctional beta-cystathionase/maltose regulon regulatory protein low > 92
Rahnella sp. WP5 0.52 EX31_RS09920 nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase 0.72 EX31_RS06865 pyridoxal phosphate-dependent aminotransferase low > 89
Desulfovibrio vulgaris Hildenborough JW710 0.32 DVU3279 cobT nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase (TIGR) 0.28 DVU0171 patB hemolysin-related protein (TIGR) low > 55
Fusobacterium nucleatum SB010 0.31 HUW76_05630 nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase 0.27 HUW76_06165 pyridoxal phosphate-dependent aminotransferase low > 35
Desulfovibrio vulgaris Miyazaki F 0.30 DvMF_2122 nicotinate-nucleotide/dimethylbenzimidazole phosphoribosyltransferase (RefSeq) 0.27 DvMF_1822 aminotransferase class I and II (RefSeq) low > 51
Pseudomonas fluorescens FW300-N2E2 0.28 Pf6N2E2_5744 Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase (EC 2.4.2.21) 0.26 Pf6N2E2_1210 putative aminotransferase — —
Pseudomonas fluorescens FW300-N1B4 0.28 Pf1N1B4_3713 Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase (EC 2.4.2.21) 0.26 Pf1N1B4_4946 putative aminotransferase low > 87
Pseudomonas fluorescens GW456-L13 0.27 PfGW456L13_4236 Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase (EC 2.4.2.21) 0.26 PfGW456L13_3090 putative aminotransferase low > 87
Bacteroides ovatus ATCC 8483 0.27 BACOVA_03275 nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase 0.32 BACOVA_04944 aminotransferase, class I/II low > 94
Ralstonia solanacearum IBSBF1503 0.27 RALBFv3_RS04480 nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase 0.22 RALBFv3_RS16055 putative C-S lyase low > 76
Pseudomonas fluorescens FW300-N2C3 0.27 AO356_19170 nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase 0.25 AO356_26930 aminotransferase low > 104
Pseudomonas fluorescens SBW25 0.26 PFLU_RS21995 nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase 0.24 PFLU_RS13630 putative C-S lyase low > 109
Pseudomonas fluorescens SBW25-INTG 0.26 PFLU_RS21995 nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase 0.24 PFLU_RS13630 putative C-S lyase low > 109
Pseudomonas sp. RS175 0.25 PFR28_03202 Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase 0.26 PFR28_02099 Cystathionine beta-lyase PatB low > 88
Bacteroides stercoris CC31F 0.25 HMPREF1181_RS15655 nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase 0.27 HMPREF1181_RS06410 pyridoxal phosphate-dependent aminotransferase low > 56
Parabacteroides merdae CL09T00C40 0.25 HMPREF1078_RS17680 nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase 0.29 HMPREF1078_RS16700 PatB family C-S lyase low > 61
Phocaeicola dorei CL03T12C01 0.25 ABI39_RS16455 nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase 0.30 ABI39_RS19290 pyridoxal phosphate-dependent aminotransferase low > 72
Phocaeicola vulgatus CL09T03C04 0.25 HMPREF1058_RS01275 nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase 0.29 HMPREF1058_RS07560 pyridoxal phosphate-dependent aminotransferase low > 67
Dechlorosoma suillum PS 0.24 Dsui_0472 nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase 0.25 Dsui_3257 bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities low > 51
Pseudomonas simiae WCS417 0.24 PS417_20030 nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase 0.24 PS417_12965 aminotransferase low > 88
Phaeobacter inhibens DSM 17395 0.22 PGA1_c07570 nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase CobT 0.23 PGA1_c00860 cystathionine beta-lyase PatB — —
Mycobacterium tuberculosis H37Rv 0.21 Rv2207 Probable nicotinate-nucleotide-dimethylbenzimidazol phosphoribosyltransferase CobT 0.20 Rv2294 Probable aminotransferase — —
Dinoroseobacter shibae DFL-12 0.19 Dshi_0788 Nicotinate-nucleotide--dimethylbenzimidazolephosphoribosyltransferase (RefSeq) 0.21 Dshi_0178 aminotransferase class I and II (RefSeq) — —
Bosea sp. OAE506 0.19 ABIE41_RS21245 nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase 0.21 ABIE41_RS12595 PatB family C-S lyase — —

Not shown: 40 genomes with orthologs for b1991 only; 8 genomes with orthologs for b1622 only