Conservation of cofitness between b0004 and b0002 in Escherichia coli BW25113

41 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Escherichia coli BW25113 1.0 b0004 thrC threonine synthase (NCBI) 1.0 b0002 thrA bifunctional aspartokinase I/homeserine dehydrogenase I (NCBI) 0.96 2
Escherichia coli BL21 1.00 ECD_00004 L-threonine synthase 1.00 ECD_00002 Bifunctional aspartokinase/homoserine dehydrogenase 1 0.83 1
Escherichia coli ECRC102 1.00 NIAGMN_08950 thrC threonine synthase 1.00 NIAGMN_08960 thrA bifunctional aspartate kinase/homoserine dehydrogenase I — —
Escherichia coli ECRC98 1.00 JDDGAC_14695 thrC threonine synthase 1.00 JDDGAC_14705 thrA bifunctional aspartate kinase/homoserine dehydrogenase I — —
Escherichia coli ECRC101 1.00 MCAODC_01615 thrC threonine synthase 1.00 MCAODC_01625 thrA bifunctional aspartate kinase/homoserine dehydrogenase I — —
Escherichia coli ECRC62 1.00 BNILDI_08170 thrC threonine synthase 0.99 BNILDI_08160 thrA bifunctional aspartate kinase/homoserine dehydrogenase I — —
Escherichia coli ECOR27 1.00 NOLOHH_03430 thrC threonine synthase 1.00 NOLOHH_03440 thrA bifunctional aspartate kinase/homoserine dehydrogenase I low > 57
Escherichia coli ECRC101 1.00 OKFHMN_11100 thrC threonine synthase 1.00 OKFHMN_11110 thrA bifunctional aspartate kinase/homoserine dehydrogenase I — —
Escherichia coli ECRC99 1.00 KEDOAH_17055 thrC threonine synthase 1.00 KEDOAH_17045 thrA bifunctional aspartate kinase/homoserine dehydrogenase I — —
Escherichia fergusonii Becca 1.00 EFB2_04039 Threonine synthase 1.00 EFB2_04041 Bifunctional aspartokinase/homoserine dehydrogenase 1 low > 86
Escherichia coli HS(pFamp)R (ATCC 700891) 1.00 OHPLBJKB_03656 Threonine synthase 0.99 OHPLBJKB_03658 Bifunctional aspartokinase/homoserine dehydrogenase 1 low > 73
Escherichia coli Nissle 1917 0.99 ECOLIN_RS00020 threonine synthase 1.00 ECOLIN_RS00010 bifunctional aspartate kinase/homoserine dehydrogenase I low > 52
Escherichia coli ECOR38 0.99 HEPCGN_09105 thrC threonine synthase 1.00 HEPCGN_09115 thrA bifunctional aspartate kinase/homoserine dehydrogenase I low > 85
Enterobacter asburiae PDN3 0.93 EX28DRAFT_3616 threonine synthase 0.90 EX28DRAFT_3614 aspartate kinase (EC 2.7.2.4) low > 76
Enterobacter sp. TBS_079 0.93 MPMX20_00712 Threonine synthase 0.90 MPMX20_00710 Bifunctional aspartokinase/homoserine dehydrogenase 1 0.96 2
Klebsiella michiganensis M5al 0.92 BWI76_RS04255 threonine synthase 0.92 BWI76_RS04245 bifunctional aspartate kinase/homoserine dehydrogenase I 0.97 1
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.91 GFF1080 Threonine synthase (EC 4.2.3.1) 0.93 GFF1078 Aspartokinase (EC 2.7.2.4) / Homoserine dehydrogenase (EC 1.1.1.3) low > 78
Rahnella sp. WP5 0.85 EX31_RS03935 threonine synthase 0.84 EX31_RS03945 bifunctional aspartate kinase/homoserine dehydrogenase I 0.98 17
Serratia liquefaciens MT49 0.84 IAI46_03040 threonine synthase 0.82 IAI46_03030 bifunctional aspartate kinase/homoserine dehydrogenase I 0.88 7
Pantoea sp. MT58 0.81 IAI47_16205 threonine synthase 0.84 IAI47_16215 bifunctional aspartate kinase/homoserine dehydrogenase I 0.97 1
Dickeya dadantii 3937 0.80 DDA3937_RS18405 threonine synthase 0.80 DDA3937_RS18415 bifunctional aspartate kinase/homoserine dehydrogenase I 0.91 3
Dickeya dianthicola ME23 0.80 DZA65_RS19475 threonine synthase 0.79 DZA65_RS19485 bifunctional aspartate kinase/homoserine dehydrogenase I 0.75 1
Erwinia tracheiphila SCR3 0.79 LU632_RS02620 thrC threonine synthase 0.82 LU632_RS02610 thrA bifunctional aspartate kinase/homoserine dehydrogenase I — —
Dickeya dianthicola 67-19 0.79 HGI48_RS18335 threonine synthase 0.79 HGI48_RS18345 bifunctional aspartate kinase/homoserine dehydrogenase I 0.73 8
Pectobacterium carotovorum WPP14 0.79 HER17_RS02805 threonine synthase 0.83 HER17_RS02795 bifunctional aspartate kinase/homoserine dehydrogenase I 0.88 52
Vibrio cholerae E7946 ATCC 55056 0.68 CSW01_11965 threonine synthase 0.61 CSW01_11975 bifunctional aspartate kinase/homoserine dehydrogenase I low > 62
Alteromonas macleodii MIT1002 0.65 MIT1002_03084 Threonine synthase 0.52 MIT1002_03086 Aspartokinase I/homoserine dehydrogenase I 0.96 14
Shewanella loihica PV-4 0.58 Shew_1081 threonine synthase (RefSeq) 0.57 Shew_1079 thrA bifunctional aspartokinase I/homeserine dehydrogenase I (RefSeq) 0.98 13
Shewanella sp. ANA-3 0.56 Shewana3_1141 threonine synthase (RefSeq) 0.56 Shewana3_1139 thrA bifunctional aspartokinase I/homeserine dehydrogenase I (RefSeq) 0.96 2
Shewanella oneidensis MR-1 0.55 SO3413 thrC threonine synthase (NCBI ptt file) 0.55 SO3415 thrA aspartokinase I/homoserine dehydrogenase, threonine-sensitive (NCBI ptt file) 0.90 55
Shewanella amazonensis SB2B 0.55 Sama_0907 threonine synthase (RefSeq) 0.53 Sama_0905 thrA bifunctional aspartokinase I/homeserine dehydrogenase I (RefSeq) 0.96 7
Phocaeicola vulgatus CL09T03C04 0.42 HMPREF1058_RS14730 threonine synthase 0.31 HMPREF1058_RS14720 bifunctional aspartate kinase/homoserine dehydrogenase I 0.98 2
Phocaeicola dorei CL03T12C01 0.42 ABI39_RS10440 threonine synthase 0.31 ABI39_RS10430 bifunctional aspartate kinase/homoserine dehydrogenase I 0.90 1
Bacteroides thetaiotaomicron VPI-5482 0.41 BT2401 threonine synthase (NCBI ptt file) 0.28 BT2403 aspartate kinase / homoserine dehydrogenase (EC 2.7.2.4; EC 1.1.1.3) (from data) 0.88 33
Bacteroides ovatus ATCC 8483 0.41 BACOVA_03023 threonine synthase 0.27 BACOVA_03021 homoserine dehydrogenase 0.99 1
Bacteroides stercoris CC31F 0.41 HMPREF1181_RS00050 threonine synthase 0.27 HMPREF1181_RS00060 bifunctional aspartate kinase/homoserine dehydrogenase I 0.99 1
Echinicola vietnamensis KMM 6221, DSM 17526 0.40 Echvi_2002 threonine synthase 0.34 Echvi_2000 aspartate kinase / homoserine dehydrogenase (EC 2.7.2.4; EC 1.1.1.3) (from data) 0.98 1
Parabacteroides merdae CL09T00C40 0.40 HMPREF1078_RS10395 threonine synthase 0.31 HMPREF1078_RS10385 bifunctional aspartate kinase/homoserine dehydrogenase I 0.99 13
Mucilaginibacter yixingensis YX-36 DSM 26809 0.40 ABZR88_RS18960 threonine synthase 0.32 ABZR88_RS18950 bifunctional aspartate kinase/homoserine dehydrogenase I — —
Pedobacter sp. GW460-11-11-14-LB5 0.40 CA265_RS23465 threonine synthase 0.31 CA265_RS23475 aspartate kinase; homoserine dehydrogenase (EC 2.7.2.4; EC 1.1.1.3) (from data) 0.88 4
Xanthomonas campestris pv. campestris strain 8004 0.31 Xcc-8004.2954.1 Threonine synthase (EC 4.2.3.1) 0.34 Xcc-8004.2957.1 Aspartokinase (EC 2.7.2.4) / Homoserine dehydrogenase (EC 1.1.1.3) 0.93 10
Lysobacter sp. OAE881 0.30 ABIE51_RS17530 threonine synthase 0.31 ABIE51_RS17520 bifunctional aspartate kinase/homoserine dehydrogenase I 0.93 36

Not shown: 52 genomes with orthologs for b0004 only; 0 genomes with orthologs for b0002 only