Conservation of cofitness between NOLOHH_15540 and NOLOHH_11810 in Escherichia coli ECOR27

40 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Escherichia coli ECOR27 1.0 NOLOHH_15540 mdtB multidrug efflux RND transporter permease subunit MdtB 1.0 NOLOHH_11810 kduD 2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase KduD 0.58 12
Escherichia coli ECRC100 1.00 OKFHMN_24195 mdtB multidrug efflux RND transporter permease subunit MdtB 0.99 OKFHMN_19925 kduD 2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase KduD low > 80
Escherichia coli ECRC98 1.00 JDDGAC_28305 mdtB multidrug efflux RND transporter permease subunit MdtB 0.99 JDDGAC_23590 kduD 2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase KduD low > 86
Escherichia coli ECRC101 1.00 MCAODC_20745 mdtB multidrug efflux RND transporter permease subunit MdtB 0.99 MCAODC_10450 kduD 2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase KduD 0.44 63
Escherichia coli ECRC99 1.00 KEDOAH_03955 mdtB multidrug efflux RND transporter permease subunit MdtB 0.99 KEDOAH_08205 kduD 2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase KduD — —
Escherichia coli ECRC102 1.00 NIAGMN_22140 mdtB multidrug efflux RND transporter permease subunit MdtB 0.99 NIAGMN_17695 kduD 2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase KduD — —
Escherichia coli Nissle 1917 1.00 ECOLIN_RS12200 multidrug efflux RND transporter permease subunit MdtB 0.98 ECOLIN_RS15950 2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase KduD low > 55
Escherichia coli BW25113 1.00 b2075 mdtB multidrug efflux system, subunit B (NCBI) 1.00 b2842 kduD 2-deoxy-D-gluconate 3-dehydrogenase (NCBI) low > 76
Escherichia fergusonii Becca 1.00 EFB2_01780 Multidrug resistance protein MdtB 0.98 EFB2_01041 2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase low > 86
Escherichia coli HS(pFamp)R (ATCC 700891) 1.00 OHPLBJKB_01629 Multidrug resistance protein MdtB 1.00 OHPLBJKB_00887 2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase low > 73
Escherichia coli ECRC62 1.00 BNILDI_14455 mdtB multidrug efflux RND transporter permease subunit MdtB 0.99 BNILDI_10290 kduD 2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase KduD low > 75
Escherichia coli BL21 1.00 ECD_01980 multidrug efflux system, subunit B 0.39 ECD_02618 putative SDR family oxidoreductase low > 61
Escherichia coli ECOR38 1.00 HEPCGN_02885 mdtB multidrug efflux RND transporter permease subunit MdtB 1.00 HEPCGN_19585 kduD 2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase KduD low > 87
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.91 GFF3854 Multidrug transporter MdtB 0.95 GFF1327 2-deoxy-D-gluconate 3-dehydrogenase (EC 1.1.1.125) low > 78
Klebsiella michiganensis M5al 0.90 BWI76_RS19255 multidrug transporter subunit MdtB 0.94 BWI76_RS23430 2-deoxy-D-gluconate 3-dehydrogenase low > 92
Enterobacter sp. TBS_079 0.90 MPMX20_03061 Multidrug resistance protein MdtB 0.94 MPMX20_03715 2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase low > 85
Enterobacter asburiae PDN3 0.90 EX28DRAFT_0483 Cation/multidrug efflux pump 0.92 EX28DRAFT_2921 2-deoxy-D-gluconate 3-dehydrogenase low > 76
Pantoea sp. MT58 0.81 IAI47_06870 MdtB/MuxB family multidrug efflux RND transporter permease subunit 0.77 IAI47_11020 2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase KduD low > 76
Erwinia tracheiphila SCR3 0.80 LU632_RS08690 MdtB/MuxB family multidrug efflux RND transporter permease subunit 0.84 LU632_RS00060 kduD 2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase KduD low > 74
Pectobacterium carotovorum WPP14 0.79 HER17_RS06320 MdtB/MuxB family multidrug efflux RND transporter permease subunit 0.87 HER17_RS11410 2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase KduD low > 75
Dickeya dadantii 3937 0.77 DDA3937_RS15265 MdtB/MuxB family multidrug efflux RND transporter permease subunit 0.87 DDA3937_RS11335 2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase KduD low > 74
Dickeya dianthicola ME23 0.77 DZA65_RS16165 MdtB/MuxB family multidrug efflux RND transporter permease subunit 0.86 DZA65_RS11720 2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase KduD low > 75
Dickeya dianthicola 67-19 0.76 HGI48_RS15345 MdtB/MuxB family multidrug efflux RND transporter permease subunit 0.86 HGI48_RS11375 2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase KduD 0.47 63
Ralstonia sp. UNC404CL21Col 0.65 ABZR87_RS19025 MdtB/MuxB family multidrug efflux RND transporter permease subunit 0.64 ABZR87_RS20810 2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase KduD low > 80
Rahnella sp. WP5 0.62 EX31_RS13380 MMPL family transporter 0.88 EX31_RS01480 2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase KduD low > 89
Pseudomonas fluorescens SBW25 0.61 PFLU_RS13430 MdtB/MuxB family multidrug efflux RND transporter permease subunit 0.29 PFLU_RS18185 SDR family oxidoreductase low > 109
Pseudomonas fluorescens SBW25-INTG 0.61 PFLU_RS13430 MdtB/MuxB family multidrug efflux RND transporter permease subunit 0.29 PFLU_RS18185 SDR family oxidoreductase low > 109
Pseudomonas simiae WCS417 0.61 PS417_12745 multidrug transporter 0.28 PS417_12050 short-chain dehydrogenase low > 88
Paraburkholderia sabiae LMG 24235 0.60 QEN71_RS23305 MdtB/MuxB family multidrug efflux RND transporter permease subunit 0.63 QEN71_RS37290 2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase KduD low > 153
Acidovorax sp. GW101-3H11 0.59 Ac3H11_3618 Cobalt-zinc-cadmium resistance protein CzcA; Cation efflux system protein CusA 0.30 Ac3H11_3445 3-oxoacyl-[acyl-carrier protein] reductase (EC 1.1.1.100) low > 79
Paraburkholderia bryophila 376MFSha3.1 0.59 H281DRAFT_06492 multidrug efflux pump 0.67 H281DRAFT_01159 2-deoxy-D-gluconate 3-dehydrogenase low > 103
Pseudomonas syringae pv. syringae B728a ΔmexB 0.59 Psyr_2483 Acriflavin resistance protein 0.30 Psyr_2568 Short-chain dehydrogenase/reductase SDR — —
Pseudomonas syringae pv. syringae B728a 0.59 Psyr_2483 Acriflavin resistance protein 0.30 Psyr_2568 Short-chain dehydrogenase/reductase SDR — —
Burkholderia phytofirmans PsJN 0.58 BPHYT_RS07785 multidrug transporter 0.62 BPHYT_RS10945 2-deoxy-D-gluconate 3-dehydrogenase low > 109
Paraburkholderia graminis OAS925 0.58 ABIE53_001783 multidrug efflux pump 0.67 ABIE53_002285 2-deoxy-D-gluconate 3-dehydrogenase low > 113
Variovorax sp. SCN45 0.56 GFF6659 Multidrug efflux system MdtABC-TolC, inner-membrane proton/drug antiporter MdtB (RND type) 0.32 GFF6751 Oxidoreductase, short-chain dehydrogenase/reductase family low > 127
Variovorax sp. OAS795 0.53 ABID97_RS20855 efflux RND transporter permease subunit 0.30 ABID97_RS22835 glucose 1-dehydrogenase low > 91
Azospirillum sp. SherDot2 0.53 MPMX19_05477 Multidrug resistance protein MdtB 0.64 MPMX19_05789 2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase low > 112
Rhodopseudomonas palustris CGA009 0.49 TX73_013310 efflux RND transporter permease subunit 0.31 TX73_024180 3-oxoacyl-ACP reductase FabG low > 86
Xanthomonas campestris pv. campestris strain 8004 0.49 Xcc-8004.4792.1 Acriflavin resistance protein 0.65 Xcc-8004.207.1 hypothetical protein low > 74
Phaeobacter inhibens DSM 17395 0.13 PGA1_78p00510 multidrug transporter MdtB 0.33 PGA1_c27390 short-chain dehydrogenase/reductase low > 62

Not shown: 26 genomes with orthologs for NOLOHH_15540 only; 13 genomes with orthologs for NOLOHH_11810 only