Conservation of cofitness between IAI46_01035 and IAI46_03035 in Serratia liquefaciens MT49

36 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Serratia liquefaciens MT49 1.0 IAI46_01035 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase 1.0 IAI46_03035 homoserine kinase 0.82 7
Rahnella sp. WP5 0.86 EX31_RS14710 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase 0.88 EX31_RS03940 homoserine kinase low > 89
Pectobacterium carotovorum WPP14 0.86 HER17_RS20685 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase 0.87 HER17_RS02800 homoserine kinase low > 75
Dickeya dianthicola ME23 0.86 DZA65_RS00875 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase 0.85 DZA65_RS19480 homoserine kinase low > 75
Dickeya dianthicola 67-19 0.86 HGI48_RS00820 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase 0.85 HGI48_RS18340 homoserine kinase 0.78 56
Dickeya dadantii 3937 0.86 DDA3937_RS20380 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase 0.85 DDA3937_RS18410 homoserine kinase low > 74
Escherichia coli ECOR38 0.84 HEPCGN_13025 metE 5-methyltetrahydropteroyltriglutamate--homocystei ne S-methyltransferase 0.80 HEPCGN_09110 thrB homoserine kinase 0.83 75
Klebsiella michiganensis M5al 0.84 BWI76_RS01280 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase 0.84 BWI76_RS04250 homoserine kinase 0.25 73
Escherichia fergusonii Becca 0.84 EFB2_04808 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase 0.80 EFB2_04040 Homoserine kinase low > 86
Escherichia coli Nissle 1917 0.84 ECOLIN_RS21980 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase 0.80 ECOLIN_RS00015 homoserine kinase low > 55
Escherichia coli BL21 0.84 ECD_03708 5-methyltetrahydropteroyltriglutamate- homocysteine S-methyltransferase 0.80 ECD_00003 homoserine kinase 0.96 10
Enterobacter asburiae PDN3 0.84 EX28DRAFT_4494 methionine synthase (B12-independent) (EC 2.1.1.14) 0.82 EX28DRAFT_3615 homoserine kinase (EC 2.7.1.39) — —
Escherichia coli HS(pFamp)R (ATCC 700891) 0.84 OHPLBJKB_04222 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase 0.80 OHPLBJKB_03657 Homoserine kinase low > 73
Escherichia coli BW25113 0.84 b3829 metE 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase (NCBI) 0.80 b0003 thrB homoserine kinase (NCBI) 0.66 31
Escherichia coli ECRC62 0.84 BNILDI_05075 metE 5-methyltetrahydropteroyltriglutamate--homocystei ne S-methyltransferase 0.80 BNILDI_08165 thrB homoserine kinase 0.98 30
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.84 GFF254 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase (EC 2.1.1.14) 0.80 GFF1079 Homoserine kinase (EC 2.7.1.39) low > 78
Escherichia coli ECRC102 0.84 NIAGMN_12080 metE 5-methyltetrahydropteroyltriglutamate--homocystei ne S-methyltransferase 0.80 NIAGMN_08955 thrB homoserine kinase — —
Escherichia coli ECOR27 0.84 NOLOHH_06455 metE 5-methyltetrahydropteroyltriglutamate--homocystei ne S-methyltransferase 0.80 NOLOHH_03435 thrB homoserine kinase 0.82 53
Pantoea sp. MT58 0.84 IAI47_18310 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase 0.87 IAI47_16210 homoserine kinase low > 76
Escherichia coli ECRC99 0.84 KEDOAH_13825 metE 5-methyltetrahydropteroyltriglutamate--homocystei ne S-methyltransferase 0.80 KEDOAH_17050 thrB homoserine kinase — —
Escherichia coli ECRC101 0.84 MCAODC_04830 metE 5-methyltetrahydropteroyltriglutamate--homocystei ne S-methyltransferase 0.80 MCAODC_01620 thrB homoserine kinase 0.82 54
Escherichia coli ECRC100 0.84 OKFHMN_14325 metE 5-methyltetrahydropteroyltriglutamate--homocystei ne S-methyltransferase 0.80 OKFHMN_11105 thrB homoserine kinase 0.99 11
Escherichia coli ECRC98 0.84 JDDGAC_17950 metE 5-methyltetrahydropteroyltriglutamate--homocystei ne S-methyltransferase 0.80 JDDGAC_14700 thrB homoserine kinase low > 86
Enterobacter sp. TBS_079 0.83 MPMX20_04451 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase 0.83 MPMX20_00711 Homoserine kinase 0.29 71
Erwinia tracheiphila SCR3 0.83 LU632_RS24030 metE 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase 0.82 LU632_RS02615 thrB homoserine kinase low > 74
Vibrio cholerae E7946 ATCC 55056 0.60 CSW01_08575 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase 0.74 CSW01_11970 homoserine kinase low > 62
Shewanella oneidensis MR-1 0.56 SO0818 metE 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase (NCBI ptt file) 0.52 SO3414 thrB homoserine kinase (NCBI ptt file) 0.92 37
Shewanella sp. ANA-3 0.55 Shewana3_3469 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase (RefSeq) 0.53 Shewana3_1140 homoserine kinase (RefSeq) low > 73
Shewanella loihica PV-4 0.55 Shew_2986 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase (RefSeq) 0.52 Shew_1080 homoserine kinase (RefSeq) 0.41 30
Shewanella amazonensis SB2B 0.53 Sama_2627 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase (RefSeq) 0.51 Sama_0906 homoserine kinase (RefSeq) 0.96 21
Mucilaginibacter yixingensis YX-36 DSM 26809 0.52 ABZR88_RS18615 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase 0.25 ABZR88_RS18955 homoserine kinase — —
Pedobacter sp. GW460-11-11-14-LB5 0.52 CA265_RS21095 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase 0.22 CA265_RS23470 homoserine kinase (EC 2.7.1.39) (from data) low > 88
Echinicola vietnamensis KMM 6221, DSM 17526 0.51 Echvi_2559 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase 0.21 Echvi_2001 homoserine kinase (EC 2.7.1.39) (from data) low > 79
Dyella japonica UNC79MFTsu3.2 0.49 ABZR86_RS03225 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase 0.16 ABZR86_RS15980 homoserine kinase (EC 2.7.1.39) (from data) low > 74
Rhodanobacter denitrificans MT42 0.48 LRK55_RS11870 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase 0.19 LRK55_RS10000 homoserine kinase — —
Rhodanobacter denitrificans FW104-10B01 0.48 LRK54_RS12135 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase 0.19 LRK54_RS10360 homoserine kinase low > 59
Mycobacterium tuberculosis H37Rv 0.44 Rv1133c Probable 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase MetE (methionine synthase, vitamin-B12 independent isozyme) 0.08 Rv1296 Probable homoserine kinase ThrB — —

Not shown: 31 genomes with orthologs for IAI46_01035 only; 7 genomes with orthologs for IAI46_03035 only