Conservation of cofitness between HER17_RS10870 and HER17_RS12260 in Pectobacterium carotovorum WPP14

37 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Pectobacterium carotovorum WPP14 1.0 HER17_RS10870 HTH-type transcriptional regulator CysB 1.0 HER17_RS12260 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE 0.95 13
Dickeya dadantii 3937 0.95 DDA3937_RS10540 HTH-type transcriptional regulator CysB 0.90 DDA3937_RS09705 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE low > 74
Dickeya dianthicola 67-19 0.95 HGI48_RS10540 HTH-type transcriptional regulator CysB 0.89 HGI48_RS09715 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE low > 71
Dickeya dianthicola ME23 0.95 DZA65_RS11020 HTH-type transcriptional regulator CysB 0.89 DZA65_RS10025 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE 0.65 21
Serratia liquefaciens MT49 0.93 IAI46_13965 HTH-type transcriptional regulator CysB 0.81 IAI46_08180 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE — —
Rahnella sp. WP5 0.93 EX31_RS09890 HTH-type transcriptional regulator CysB 0.74 EX31_RS11470 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE 0.93 46
Klebsiella michiganensis M5al 0.92 BWI76_RS11930 LysR family transcriptional regulator CysB 0.83 BWI76_RS18955 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase — —
Erwinia tracheiphila SCR3 0.92 LU632_RS12550 cysB HTH-type transcriptional regulator CysB 0.79 LU632_RS08915 hisIE bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE — —
Enterobacter sp. TBS_079 0.91 MPMX20_02501 HTH-type transcriptional regulator CysB 0.85 MPMX20_03008 Histidine biosynthesis bifunctional protein HisIE — —
Escherichia coli ECOR38 0.91 HEPCGN_25600 cysB HTH-type transcriptional regulator CysB 0.81 HEPCGN_03190 hisIE bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE 0.77 53
Escherichia coli ECRC99 0.91 KEDOAH_26165 cysB HTH-type transcriptional regulator CysB 0.75 KEDOAH_03665 hisIE bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE — —
Escherichia coli BW25113 0.91 b1275 cysB DNA-binding transcriptional dual regulator, O-acetyl-L-serine-binding (NCBI) 0.82 b2026 hisI bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase protein (NCBI) — —
Escherichia coli ECRC62 0.91 BNILDI_18415 cysB HTH-type transcriptional regulator CysB 0.80 BNILDI_14710 hisIE bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE — —
Enterobacter asburiae PDN3 0.91 EX28DRAFT_0946 Transcriptional regulator 0.84 EX28DRAFT_0533 phosphoribosyl-AMP cyclohydrolase (EC 3.5.4.19)/phosphoribosyl-ATP pyrophosphatase (EC 3.6.1.31) — —
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.91 GFF2712 Cys regulon transcriptional activator CysB 0.74 GFF3906 Phosphoribosyl-AMP cyclohydrolase (EC 3.5.4.19) / Phosphoribosyl-ATP pyrophosphatase (EC 3.6.1.31) — —
Escherichia fergusonii Becca 0.91 EFB2_02652 HTH-type transcriptional regulator CysB 0.75 EFB2_01830 Histidine biosynthesis bifunctional protein HisIE — —
Escherichia coli BL21 0.91 ECD_01251 N-acetylserine-responsive cysteine regulon transcriptional activator; autorepressor 0.82 ECD_01928 phosphoribosyl-AMP cyclohydrolase and phosphoribosyl-ATP pyrophosphatase — —
Escherichia coli ECRC102 0.91 NIAGMN_26770 cysB HTH-type transcriptional regulator CysB 0.75 NIAGMN_22430 hisIE bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE — —
Escherichia coli HS(pFamp)R (ATCC 700891) 0.91 OHPLBJKB_02409 HTH-type transcriptional regulator CysB 0.81 OHPLBJKB_01674 Histidine biosynthesis bifunctional protein HisIE low > 73
Escherichia coli ECRC101 0.91 MCAODC_15665 cysB HTH-type transcriptional regulator CysB 0.75 MCAODC_20455 hisIE bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE — —
Escherichia coli ECRC98 0.91 JDDGAC_05145 cysB HTH-type transcriptional regulator CysB 0.75 JDDGAC_28595 hisIE bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE — —
Escherichia coli ECRC100 0.91 OKFHMN_02600 cysB HTH-type transcriptional regulator CysB 0.75 OKFHMN_24485 hisIE bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE — —
Escherichia coli Nissle 1917 0.91 ECOLIN_RS07680 HTH-type transcriptional regulator CysB 0.75 ECOLIN_RS11975 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE — —
Escherichia coli ECOR27 0.91 NOLOHH_20265 cysB HTH-type transcriptional regulator CysB 0.76 NOLOHH_15800 hisIE bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE — —
Pantoea sp. MT58 0.90 IAI47_09240 HTH-type transcriptional regulator CysB 0.82 IAI47_07060 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE 0.69 24
Vibrio cholerae E7946 ATCC 55056 0.80 CSW01_09545 HTH-type transcriptional regulator CysB 0.64 CSW01_05780 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase — —
Alteromonas macleodii MIT1002 0.78 MIT1002_02005 Cys regulon transcriptional activator 0.63 MIT1002_02639 Phosphoribosyl-ATP pyrophosphatase — —
Shewanella amazonensis SB2B 0.75 Sama_1324 cysB transcriptional regulator CysB (RefSeq) 0.58 Sama_1948 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase protein (RefSeq) — —
Shewanella oneidensis MR-1 0.75 SO2649 cysB cys regulon transcriptional activator (NCBI ptt file) 0.61 SO2067 hisI phosphoribosyl-ATP pyrophosphatase/phosphoribosyl-AMP cyclohydrolase (NCBI ptt file) 0.81 48
Shewanella loihica PV-4 0.75 Shew_1624 cysB transcriptional regulator CysB (RefSeq) 0.59 Shew_2204 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase protein (RefSeq) — —
Shewanella sp. ANA-3 0.75 Shewana3_1731 cysB transcriptional regulator CysB (RefSeq) 0.60 Shewana3_1847 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase protein (RefSeq) — —
Rhodanobacter sp. FW510-T8 0.37 OKGIIK_05975 lysR CysB family transcriptional regulator 0.55 OKGIIK_04980 hisIE bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE low > 52
Rhodanobacter denitrificans FW104-10B01 0.36 LRK54_RS00915 LysR substrate-binding domain-containing protein 0.55 LRK54_RS01575 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE 0.72 14
Rhodanobacter denitrificans MT42 0.36 LRK55_RS00690 LysR substrate-binding domain-containing protein 0.56 LRK55_RS01355 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE low > 63
Dyella japonica UNC79MFTsu3.2 0.35 ABZR86_RS05885 LysR substrate-binding domain-containing protein 0.54 ABZR86_RS06700 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE 0.93 43
Lysobacter sp. OAE881 0.34 ABIE51_RS15850 LysR family transcriptional regulator 0.49 ABIE51_RS13295 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE 0.95 37
Xanthomonas campestris pv. campestris strain 8004 0.30 Xcc-8004.1249.1 Transcriptional regulator 0.55 Xcc-8004.2942.1 Phosphoribosyl-AMP cyclohydrolase (EC 3.5.4.19) / Phosphoribosyl-ATP pyrophosphatase (EC 3.6.1.31) 0.58 57
Mucilaginibacter yixingensis YX-36 DSM 26809 0.16 ABZR88_RS05415 LysR substrate-binding domain-containing protein 0.52 ABZR88_RS06845 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE — —

Not shown: 22 genomes with orthologs for HER17_RS10870 only; 12 genomes with orthologs for HER17_RS12260 only