Conservation of cofitness between GFF3670 and GFF5305 in Sphingobium sp. HT1-2

38 genomes with putative orthologs of both genes

Organism	Ratio1	Gene1	Name1	Description1	Ratio2	Gene2	Name2	Description2	Cofit	Rank
Sphingobium sp. HT1-2	1.0	GFF3670		3-deoxy-manno-octulosonate cytidylyltransferase (EC 2.7.7.38)	1.0	GFF5305		Metal-dependent hydrolases of the beta-lactamase superfamily I; PhnP protein	0.70	4
Dinoroseobacter shibae DFL-12	0.29	Dshi_3575		3-deoxy-D-manno-octulosonate cytidylyltransferase (RefSeq)	0.36	Dshi_0919		beta-lactamase domain protein (RefSeq)	—	—
Phaeobacter inhibens DSM 17395	0.26	PGA1_c34490		3-deoxy-manno-octulosonate cytidylyltransferase KdsB	0.35	PGA1_c07980		metallo beta-lactamase domain-containing protein	—	—
Pontibacter actiniarum KMM 6156, DSM 19842	0.24	CA264_03795		3-deoxy-manno-octulosonate cytidylyltransferase	0.24	CA264_12090		hydrolase	—	—
Brevundimonas sp. GW460-12-10-14-LB2	0.23	A4249_RS15095		3-deoxy-manno-octulosonate cytidylyltransferase	0.40	A4249_RS04760		MBL fold metallo-hydrolase	—	—
Phocaeicola vulgatus CL09T03C04	0.22	HMPREF1058_RS03880		3-deoxy-manno-octulosonate cytidylyltransferase	0.24	HMPREF1058_RS15240		MBL fold metallo-hydrolase	—	—
Bacteroides ovatus ATCC 8483	0.22	BACOVA_02480		3-deoxy-D-manno-octulosonate cytidylyltransferase	0.18	BACOVA_00207		metallo-beta-lactamase domain protein	—	—
Bacteroides thetaiotaomicron VPI-5482	0.22	BT0745		3-deoxy-manno-octulosonate cytidylyltransferase (NCBI ptt file)	0.26	BT1367		hydrolase, metal-dependent (NCBI ptt file)	—	—
Phocaeicola dorei CL03T12C01	0.22	ABI39_RS17345		3-deoxy-manno-octulosonate cytidylyltransferase	0.24	ABI39_RS11270		MBL fold metallo-hydrolase	—	—
Bacteroides stercoris CC31F	0.21	HMPREF1181_RS14845		3-deoxy-manno-octulosonate cytidylyltransferase	0.24	HMPREF1181_RS10930		MBL fold metallo-hydrolase	—	—
Xanthobacter sp. DMC5	0.21	GFF1653		3-deoxy-manno-octulosonate cytidylyltransferase	0.39	GFF837		hypothetical protein	—	—
Pedobacter sp. GW460-11-11-14-LB5	0.21	CA265_RS07450		3-deoxy-D-manno-octulosonate cytidylyltransferase	0.24	CA265_RS04490		MBL fold metallo-hydrolase	low	> 88
Parabacteroides merdae CL09T00C40	0.21	HMPREF1078_RS15745		3-deoxy-manno-octulosonate cytidylyltransferase	0.25	HMPREF1078_RS00670		MBL fold metallo-hydrolase	—	—
Mucilaginibacter yixingensis YX-36 DSM 26809	0.21	ABZR88_RS13860		3-deoxy-manno-octulosonate cytidylyltransferase	0.20	ABZR88_RS03775		MBL fold metallo-hydrolase	—	—
Rhodospirillum rubrum S1H	0.20	Rru_A3163		3-deoxy-D-manno-octulosonate cytidylyltransferase (NCBI)	0.35	Rru_A1699		Beta-lactamase-like (NCBI)	—	—
Caulobacter crescentus NA1000 Δfur	0.20	CCNA_03029		3-deoxy-manno-octulosonate cytidylyltransferase	0.40	CCNA_01897		metal-dependent hydrolase	—	—
Caulobacter crescentus NA1000	0.20	CCNA_03029		3-deoxy-manno-octulosonate cytidylyltransferase	0.40	CCNA_01897		metal-dependent hydrolase	—	—
Magnetospirillum magneticum AMB-1	0.20	AMB_RS21095		3-deoxy-manno-octulosonate cytidylyltransferase	0.37	AMB_RS12290		MBL fold metallo-hydrolase	—	—
Rhizobium sp. OAE497	0.20	ABIE40_RS00240		3-deoxy-manno-octulosonate cytidylyltransferase	0.38	ABIE40_RS09475		MBL fold metallo-hydrolase	—	—
Azospirillum sp. SherDot2	0.20	MPMX19_02161		3-deoxy-manno-octulosonate cytidylyltransferase	0.40	MPMX19_01470		hypothetical protein	—	—
Rhodopseudomonas palustris CGA009	0.20	TX73_019140		3-deoxy-manno-octulosonate cytidylyltransferase	0.37	TX73_014395		MBL fold metallo-hydrolase	—	—
Azospirillum brasilense Sp245	0.19	AZOBR_RS03860		3-deoxy-manno-octulosonate cytidylyltransferase	0.42	AZOBR_RS08800		PhnP	—	—
Agrobacterium fabrum C58	0.19	Atu0100		3-deoxy-manno-octulosonate cytidylyltransferase	0.38	Atu1494		metal dependent hydrolase	—	—
Pseudomonas syringae pv. syringae B728a ΔmexB	0.19	Psyr_1636		3-deoxy-D-manno-octulosonate cytidylyltransferase	0.11	Psyr_2259		Beta-lactamase-like protein	—	—
Sinorhizobium meliloti 1021	0.19	SMc02898		3-deoxy-manno-octulosonate cytidylyltransferase	0.37	SMc01194		hypothetical protein	—	—
Pseudomonas syringae pv. syringae B728a	0.19	Psyr_1636		3-deoxy-D-manno-octulosonate cytidylyltransferase	0.11	Psyr_2259		Beta-lactamase-like protein	—	—
Pantoea agglomerans CFBP13505 P0401	0.19	PagCFBP13505_RS04515		3-deoxy-manno-octulosonate cytidylyltransferase	0.10	PagCFBP13505_RS01690		phosphonate metabolism protein PhnP	—	—
Methylophilus sp. DMC18	0.19	GFF781		3-deoxy-manno-octulosonate cytidylyltransferase	0.31	GFF633		Phosphoribosyl 1,2-cyclic phosphate phosphodiesterase	—	—
Serratia liquefaciens MT49	0.19	IAI46_08700		3-deoxy-manno-octulosonate cytidylyltransferase	0.14	IAI46_02060		phosphonate metabolism protein PhnP	—	—
Pantoea sp. MT58	0.19	IAI47_12815		3-deoxy-manno-octulosonate cytidylyltransferase	0.13	IAI47_07795		phosphonate metabolism protein PhnP	—	—
Dickeya dianthicola ME23	0.19	DZA65_RS10195		3-deoxy-manno-octulosonate cytidylyltransferase	0.12	DZA65_RS07995		phosphonate metabolism protein PhnP	—	—
Pseudomonas stutzeri RCH2	0.19	Psest_1676		3-deoxy-D-manno-octulosonate cytidylyltransferase	0.11	Psest_0088		phosphonate metabolism protein PhnP	—	—
Bosea sp. OAE506	0.19	ABIE41_RS23950		3-deoxy-manno-octulosonate cytidylyltransferase	0.35	ABIE41_RS15940		MBL fold metallo-hydrolase	—	—
Pseudomonas fluorescens SBW25-INTG	0.18	PFLU_RS18375		3-deoxy-manno-octulosonate cytidylyltransferase	0.11	PFLU_RS08800		phosphonate metabolism protein PhnP	—	—
Pseudomonas fluorescens SBW25	0.18	PFLU_RS18375		3-deoxy-manno-octulosonate cytidylyltransferase	0.11	PFLU_RS08800		phosphonate metabolism protein PhnP	—	—
Dickeya dianthicola 67-19	0.18	HGI48_RS09865		3-deoxy-manno-octulosonate cytidylyltransferase	0.12	HGI48_RS07490		phosphonate metabolism protein PhnP	—	—
Dickeya dadantii 3937	0.18	DDA3937_RS09855		3-deoxy-manno-octulosonate cytidylyltransferase	0.12	DDA3937_RS07640		phosphonate metabolism protein PhnP	—	—
Echinicola vietnamensis KMM 6221, DSM 17526	0.18	Echvi_3052		3-deoxy-D-manno-octulosonate cytidylyltransferase	0.24	Echvi_2319		Metal-dependent hydrolases of the beta-lactamase superfamily I	low	> 79
Cellulophaga baltica 18	0.17	M666_RS11545		3-deoxy-manno-octulosonate cytidylyltransferase	0.30	M666_RS13955		MBL fold metallo-hydrolase	—	—

Not shown: 74 genomes with orthologs for GFF3670 only; 1 genomes with orthologs for GFF5305 only