Conservation of cofitness between GFF3399 and GFF4455 in Sphingobium sp. HT1-2

41 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Sphingobium sp. HT1-2 1.0 GFF3399 Lactate-responsive regulator LldR in Enterobacteria, GntR family 1.0 GFF4455 Alcohol dehydrogenase (EC 1.1.1.1) 0.78 3
Castellaniella sp019104865 MT123 0.37 ABCV34_RS10290 transcriptional regulator LldR 0.79 ABCV34_RS02710 alcohol dehydrogenase AdhP 0.24 40
Enterobacter sp. TBS_079 0.36 MPMX20_00130 Putative L-lactate dehydrogenase operon regulatory protein 0.38 MPMX20_02371 Alcohol dehydrogenase, propanol-preferring low > 85
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.36 GFF410 Lactate-responsive regulator LldR in Enterobacteria, GntR family 0.37 GFF2557 Alcohol dehydrogenase (EC 1.1.1.1) 0.36 39
Enterobacter asburiae PDN3 0.36 EX28DRAFT_3854 Transcriptional regulators 0.37 EX28DRAFT_1101 Zn-dependent alcohol dehydrogenases low > 76
Escherichia coli ECOR27 0.36 NOLOHH_07655 lldR transcriptional regulator LldR 0.38 NOLOHH_19040 adhP alcohol dehydrogenase AdhP low > 76
Escherichia coli ECRC62 0.36 BNILDI_03860 lldR transcriptional regulator LldR 0.38 BNILDI_17525 adhP alcohol dehydrogenase AdhP low > 75
Klebsiella pneumoniae MKP103 0.36 KDGMDA_07875 transcriptional regulator LldR 0.38 KDGMDA_22740 alcohol dehydrogenase AdhP low > 95
Escherichia coli BL21 0.35 ECD_03462 dual role activator/repressor for lldPRD operon 0.37 ECD_01436 ethanol-active dehydrogenase/acetaldehyde-active reductase — —
Escherichia coli BW25113 0.35 b3604 lldR DNA-binding transcriptional repressor (NCBI) 0.37 b1478 adhP alcohol dehydrogenase (VIMSS) low > 76
Escherichia coli HS(pFamp)R (ATCC 700891) 0.35 OHPLBJKB_00095 Putative L-lactate dehydrogenase operon regulatory protein 0.37 OHPLBJKB_02239 Alcohol dehydrogenase, propanol-preferring low > 74
Pantoea sp. MT58 0.35 IAI47_15025 transcriptional regulator LldR 0.34 IAI47_08620 alcohol dehydrogenase AdhP low > 76
Klebsiella michiganensis M5al 0.35 BWI76_RS27190 transcriptional regulator LldR 0.36 BWI76_RS13800 zinc-dependent alcohol dehydrogenase low > 92
Escherichia coli Nissle 1917 0.35 ECOLIN_RS20575 transcriptional regulator LldR 0.38 ECOLIN_RS08520 alcohol dehydrogenase AdhP low > 55
Escherichia coli ECRC101 0.35 MCAODC_06285 lldR transcriptional regulator LldR 0.38 MCAODC_16575 adhP alcohol dehydrogenase AdhP low > 87
Escherichia coli ECRC98 0.35 JDDGAC_19400 lldR transcriptional regulator LldR 0.38 JDDGAC_03855 adhP alcohol dehydrogenase AdhP low > 87
Escherichia coli ECRC99 0.35 KEDOAH_12375 lldR transcriptional regulator LldR 0.38 KEDOAH_27075 adhP alcohol dehydrogenase AdhP — —
Escherichia coli ECOR38 0.35 HEPCGN_14615 lldR transcriptional regulator LldR 0.38 HEPCGN_26430 adhP alcohol dehydrogenase AdhP low > 88
Escherichia coli ECRC102 0.35 NIAGMN_13535 lldR transcriptional regulator LldR 0.38 NIAGMN_25495 adhP alcohol dehydrogenase AdhP low > 80
Escherichia coli ECRC100 0.35 OKFHMN_15775 lldR transcriptional regulator LldR 0.38 OKFHMN_01365 adhP alcohol dehydrogenase AdhP low > 79
Escherichia fergusonii Becca 0.35 EFB2_00206 Putative L-lactate dehydrogenase operon regulatory protein 0.38 EFB2_02513 Alcohol dehydrogenase, propanol-preferring low > 86
Pantoea agglomerans CFBP13505 P0401 0.34 PagCFBP13505_RS10135 transcriptional regulator LldR 0.35 PagCFBP13505_RS02445 alcohol dehydrogenase AdhP low > 74
Pseudomonas segetis P6 0.28 MPMX49_01174 Pyruvate dehydrogenase complex repressor 0.74 MPMX49_00156 Alcohol dehydrogenase low > 75
Pseudomonas aeruginosa PA14 0.28 IKLFDK_29745 transcriptional regulator PdhR 0.75 IKLFDK_26290 alcohol dehydrogenase AdhP low > 98
Pseudomonas aeruginosa PUPa3 0.28 DQ20_RS52435 FCD domain-containing protein 0.75 DQ20_RS57865 adhP;inference=COORDINATES alcohol dehydrogenase AdhP low > 101
Pseudomonas aeruginosa MRSN321 0.28 DY961_RS09605 FCD domain-containing protein 0.75 DY961_RS25410 adhP;inference=COORDINATES alcohol dehydrogenase AdhP low > 100
Magnetospirillum magneticum AMB-1 0.27 AMB_RS01210 FCD domain-containing protein 0.14 AMB_RS10835 6-hydroxycyclohex-1-ene-1-carbonyl-CoA dehydrogenase — —
Pseudomonas sp. BP01 0.26 JOY50_RS26710 FCD domain-containing protein 0.36 JOY50_RS04025 adhP alcohol dehydrogenase AdhP low > 84
Pseudomonas putida KT2440 0.25 PP_4734 DNA-binding transcriptional dual regulator, LldR-L-lactate 0.35 PP_3839 short-chain alcohol dehydrogenase low > 96
Burkholderia phytofirmans PsJN 0.23 BPHYT_RS26990 GntR family transcriptional regulator 0.27 BPHYT_RS28135 alcohol dehydrogenase low > 109
Erwinia tracheiphila SCR3 0.22 LU632_RS03075 pdhR pyruvate dehydrogenase complex transcriptional repressor PdhR 0.38 LU632_RS00630 adhP alcohol dehydrogenase AdhP low > 73
Serratia liquefaciens MT49 0.22 IAI46_21330 pyruvate dehydrogenase complex transcriptional repressor PdhR 0.37 IAI46_12310 alcohol dehydrogenase AdhP low > 87
Erwinia tracheiphila HP pepo 2.2 0.21 IJEDHG_05795 Pyruvate dehydrogenase complex repressor 0.38 IJEDHG_10510 adhP alcohol dehydrogenase AdhP low > 61
Paraburkholderia sabiae LMG 24235 0.21 QEN71_RS10135 FadR/GntR family transcriptional regulator 0.27 QEN71_RS33145 alcohol dehydrogenase low > 153
Shewanella oneidensis MR-1 0.21 SO0423 pdhR pyruvate dehydrogenase complex repressor (NCBI ptt file) 0.19 SO4673 tdh threonine 3-dehydrogenase (NCBI ptt file) low > 76
Vibrio cholerae E7946 ATCC 55056 0.21 CSW01_12225 pyruvate dehydrogenase complex transcriptional repressor PdhR 0.18 CSW01_18565 L-threonine 3-dehydrogenase low > 62
Erwinia amylovora T8 0.20 OLJFJH_01000 pyruvate dehydrogenase complex transcriptional repressor PdhR 0.35 OLJFJH_17610 alcohol dehydrogenase AdhP low > 58
Dinoroseobacter shibae DFL-12 0.20 Dshi_3026 GntR domain protein (RefSeq) 0.61 Dshi_0931 Alcohol dehydrogenase GroES domain protein (RefSeq) 0.32 61
Sinorhizobium meliloti 1021 0.20 SMc00829 transcriptional regulator 0.70 SMa1296 alcohol dehydrogenase low > 103
Azospirillum brasilense Sp245 0.19 AZOBR_RS25130 GntR family transcriptional regulator 0.71 AZOBR_RS13230 alcohol dehydrogenase low > 97
Agrobacterium fabrum C58 0.17 Atu0662 transcriptional regulator, GntR family 0.71 Atu0626 alcohol dehydrogenase low > 89
Cupriavidus basilensis FW507-4G11 0.15 RR42_RS21300 GntR family transcriptional regulator 0.78 RR42_RS34260 Alcohol dehydrogenase (EC 1.1.1.1) (from data) low > 128

Not shown: 37 genomes with orthologs for GFF3399 only; 14 genomes with orthologs for GFF4455 only