Conservation of cofitness between ECD_02743 and ECD_01981 in Escherichia coli BL21

45 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Escherichia coli BL21 1.0 ECD_02743 5-formyltetrahydrofolate cyclo-ligase family protein 1.0 ECD_01981 multidrug efflux system, subunit C low > 61
Escherichia fergusonii Becca 1.00 EFB2_00991 5-formyltetrahydrofolate cyclo-ligase 0.99 EFB2_01779 Multidrug resistance protein MdtC low > 86
Escherichia coli HS(pFamp)R (ATCC 700891) 1.00 OHPLBJKB_00804 5-formyltetrahydrofolate cyclo-ligase 1.00 OHPLBJKB_01628 Multidrug resistance protein MdtC low > 73
Escherichia coli ECOR27 1.00 NOLOHH_11395 ygfA 5-formyltetrahydrofolate cyclo-ligase 1.00 NOLOHH_15535 mdtC multidrug efflux RND transporter permease subunit MdtC low > 75
Escherichia coli ECRC62 1.00 BNILDI_09930 ygfA 5-formyltetrahydrofolate cyclo-ligase 1.00 BNILDI_14450 mdtC multidrug efflux RND transporter permease subunit MdtC low > 75
Escherichia coli ECRC100 1.00 OKFHMN_19485 ygfA 5-formyltetrahydrofolate cyclo-ligase 1.00 OKFHMN_24190 mdtC multidrug efflux RND transporter permease subunit MdtC low > 80
Escherichia coli ECRC99 1.00 KEDOAH_08655 ygfA 5-formyltetrahydrofolate cyclo-ligase 1.00 KEDOAH_03960 mdtC multidrug efflux RND transporter permease subunit MdtC — —
Escherichia coli ECRC102 1.00 NIAGMN_17250 ygfA 5-formyltetrahydrofolate cyclo-ligase 1.00 NIAGMN_22135 mdtC multidrug efflux RND transporter permease subunit MdtC — —
Escherichia coli ECRC98 1.00 JDDGAC_23125 ygfA 5-formyltetrahydrofolate cyclo-ligase 1.00 JDDGAC_28300 mdtC multidrug efflux RND transporter permease subunit MdtC low > 86
Escherichia coli ECRC101 1.00 MCAODC_10005 ygfA 5-formyltetrahydrofolate cyclo-ligase 1.00 MCAODC_20750 mdtC multidrug efflux RND transporter permease subunit MdtC low > 87
Escherichia coli BW25113 0.99 b2912 ygfA putative ligase (VIMSS) 1.00 b2076 mdtC multidrug efflux system, subunit C (NCBI) low > 76
Escherichia coli Nissle 1917 0.99 ECOLIN_RS16205 5-formyltetrahydrofolate cyclo-ligase 0.99 ECOLIN_RS12205 multidrug efflux RND transporter permease subunit MdtC — —
Escherichia coli ECOR38 0.99 HEPCGN_18775 ygfA 5-formyltetrahydrofolate cyclo-ligase 0.99 HEPCGN_02880 mdtC multidrug efflux RND transporter permease subunit MdtC low > 87
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.85 GFF3012 5-formyltetrahydrofolate cyclo-ligase (EC 6.3.3.2) 0.90 GFF3853 Multidrug transporter MdtC low > 78
Enterobacter sp. TBS_079 0.82 MPMX20_03770 5-formyltetrahydrofolate cyclo-ligase 0.92 MPMX20_03062 Multidrug resistance protein MdtC low > 85
Klebsiella michiganensis M5al 0.79 BWI76_RS23915 5-formyltetrahydrofolate cyclo-ligase 0.90 BWI76_RS19260 multidrug transporter subunit MdtC low > 92
Enterobacter asburiae PDN3 0.78 EX28DRAFT_2964 5,10-methenyltetrahydrofolate synthetase 0.92 EX28DRAFT_0482 Cation/multidrug efflux pump low > 76
Pectobacterium carotovorum WPP14 0.69 HER17_RS19095 5-formyltetrahydrofolate cyclo-ligase 0.79 HER17_RS06315 multidrug efflux RND transporter permease subunit MdtC low > 75
Serratia liquefaciens MT49 0.66 IAI46_20895 5-formyltetrahydrofolate cyclo-ligase 0.82 IAI46_18980 multidrug efflux RND transporter permease subunit MdtC low > 86
Rahnella sp. WP5 0.64 EX31_RS21480 5-formyltetrahydrofolate cyclo-ligase 0.53 EX31_RS13375 MMPL family transporter low > 89
Dickeya dadantii 3937 0.64 DDA3937_RS02410 5-formyltetrahydrofolate cyclo-ligase 0.78 DDA3937_RS15270 multidrug efflux RND transporter permease subunit MdtC low > 74
Dickeya dianthicola 67-19 0.62 HGI48_RS02370 5-formyltetrahydrofolate cyclo-ligase 0.78 HGI48_RS15350 multidrug efflux RND transporter permease subunit MdtC low > 71
Erwinia tracheiphila SCR3 0.60 LU632_RS05860 5-formyltetrahydrofolate cyclo-ligase 0.73 LU632_RS08685 mdtC multidrug efflux RND transporter permease subunit MdtC — —
Pantoea sp. MT58 0.59 IAI47_03730 5-formyltetrahydrofolate cyclo-ligase 0.79 IAI47_06865 multidrug efflux RND transporter permease subunit MdtC low > 76
Dickeya dianthicola ME23 0.59 DZA65_RS02475 5-formyltetrahydrofolate cyclo-ligase 0.78 DZA65_RS16170 multidrug efflux RND transporter permease subunit MdtC low > 75
Pseudomonas stutzeri RCH2 0.30 Psest_0170 5,10-methenyltetrahydrofolate synthetase 0.53 Psest_2140 Cation/multidrug efflux pump low > 67
Pseudomonas fluorescens FW300-N2E3 0.29 AO353_08780 5-formyltetrahydrofolate cyclo-ligase 0.55 AO353_22900 acriflavine resistance protein B low > 101
Pseudomonas fluorescens SBW25-INTG 0.29 PFLU_RS28965 5-formyltetrahydrofolate cyclo-ligase 0.53 PFLU_RS13435 MMPL family transporter low > 109
Pseudomonas simiae WCS417 0.29 PS417_27305 5-formyltetrahydrofolate cyclo-ligase 0.52 PS417_12750 acriflavine resistance protein B low > 88
Pseudomonas fluorescens SBW25 0.29 PFLU_RS28965 5-formyltetrahydrofolate cyclo-ligase 0.53 PFLU_RS13435 MMPL family transporter low > 109
Pseudomonas sp. S08-1 0.28 OH686_11225 5-formyltetrahydrofolate cyclo-ligase 0.55 OH686_00930 Multidrug efflux system MdtABC-TolC, inner-membrane proton/drug antiporter MdtC (RND type) low > 80
Pseudomonas fluorescens GW456-L13 0.28 PfGW456L13_892 5-formyltetrahydrofolate cyclo-ligase (EC 6.3.3.2) 0.54 PfGW456L13_3265 Acriflavin resistance plasma membrane protein low > 87
Pseudomonas putida KT2440 0.27 PP_5203 5-formyltetrahydrofolate cyclo-ligase 0.52 PP_3583 multidrug efflux transport system - membrane subunit low > 96
Pseudomonas fluorescens FW300-N2E2 0.27 Pf6N2E2_4476 5-formyltetrahydrofolate cyclo-ligase (EC 6.3.3.2) 0.52 Pf6N2E2_1271 Acriflavin resistance plasma membrane protein low > 103
Pseudomonas syringae pv. syringae B728a ΔmexB 0.27 Psyr_0317 5-formyltetrahydrofolate cyclo-ligase 0.53 Psyr_2484 Acriflavin resistance protein low > 86
Pseudomonas syringae pv. syringae B728a 0.27 Psyr_0317 5-formyltetrahydrofolate cyclo-ligase 0.53 Psyr_2484 Acriflavin resistance protein low > 86
Pseudomonas sp. RS175 0.27 PFR28_04325 5-formyltetrahydrofolate cyclo-ligase 0.51 PFR28_02193 Multidrug resistance protein MdtC low > 88
Pseudomonas fluorescens FW300-N2C3 0.27 AO356_12990 5-formyltetrahydrofolate cyclo-ligase 0.51 AO356_25880 acriflavine resistance protein B low > 104
Acinetobacter radioresistens SK82 0.25 MPMX26_02298 5-formyltetrahydrofolate cyclo-ligase 0.23 MPMX26_02516 Multidrug resistance protein MdtC low > 36
Agrobacterium fabrum C58 0.23 Atu3731 5-formyltetrahydrofolate cyclo-ligase 0.39 Atu3274 AcrB/AcrD/AcrF family protein low > 89
Sinorhizobium meliloti 1021 0.21 SMc03974 hypothetical protein 0.23 SMc01457 transport transmembrane protein low > 103
Pontibacter actiniarum KMM 6156, DSM 19842 0.20 CA264_15880 5-formyltetrahydrofolate cyclo-ligase 0.24 CA264_13040 acriflavin resistance protein low > 74
Desulfovibrio vulgaris Miyazaki F 0.20 DvMF_2318 5-formyltetrahydrofolate cyclo-ligase (RefSeq) 0.43 DvMF_1515 acriflavin resistance protein (RefSeq) low > 51
Rhizobium sp. OAE497 0.20 ABIE40_RS15645 5-formyltetrahydrofolate cyclo-ligase 0.38 ABIE40_RS05760 efflux RND transporter permease subunit low > 107
Azospirillum brasilense Sp245 0.18 AZOBR_RS09025 5-formyltetrahydrofolate cyclo-ligase 0.44 AZOBR_RS14670 multidrug transporter low > 97
Rhodopseudomonas palustris CGA009 0.18 TX73_023120 5-formyltetrahydrofolate cyclo-ligase 0.49 TX73_018025 multidrug efflux RND transporter permease subunit low > 86

Not shown: 24 genomes with orthologs for ECD_02743 only; 15 genomes with orthologs for ECD_01981 only