| Organism | Ratio1 | Gene1 | Name1 | Description1 | Ratio2 | Gene2 | Name2 | Description2 | Cofit | Rank |
| Vibrio cholerae E7946 ATCC 55056 | 1.0 | CSW01_01380 | | D-2-hydroxyacid dehydrogenase | 1.0 | CSW01_13525 | | DNA-binding transcriptional regulator CytR | 0.78 | 1 |
| Shewanella amazonensis SB2B | 0.39 | Sama_3039 | | Phosphoglycerate dehydrogenase (EC 1.1.1.95) (from data) | 0.36 | Sama_0294 | | LacI family transcription regulator (RefSeq) | low | > 62 |
| Shewanella loihica PV-4 | 0.39 | Shew_0553 | | D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding (RefSeq) | 0.21 | Shew_1870 | | LacI family transcription regulator (RefSeq) | low | > 60 |
| Alteromonas macleodii MIT1002 | 0.29 | MIT1002_03160 | | Glyoxylate/hydroxypyruvate reductase A | 0.39 | MIT1002_00363 | | HTH-type transcriptional repressor CytR | low | > 70 |
| Pectobacterium carotovorum WPP14 | 0.27 | HER17_RS02495 | | D-2-hydroxyacid dehydrogenase | 0.66 | HER17_RS00865 | | DNA-binding transcriptional regulator CytR | low | > 75 |
| Pseudomonas sp. DMC3 | 0.25 | GFF2313 | | Glyoxylate/hydroxypyruvate reductase A | 0.38 | GFF1074 | | HTH-type transcriptional repressor CytR | low | > 89 |
| Pseudomonas fluorescens FW300-N1B4 | 0.25 | Pf1N1B4_3347 | | D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) | 0.38 | Pf1N1B4_4095 | | Transcriptional regulator, LacI family | — | — |
| Dickeya dadantii 3937 | 0.25 | DDA3937_RS18695 | | D-2-hydroxyacid dehydrogenase | 0.61 | DDA3937_RS00930 | | DNA-binding transcriptional regulator CytR | low | > 74 |
| Pseudomonas fluorescens FW300-N2E2 | 0.25 | Pf6N2E2_2725 | | D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) | 0.39 | Pf6N2E2_322 | | Transcriptional regulator, LacI family | low | > 103 |
| Dickeya dianthicola 67-19 | 0.25 | HGI48_RS18625 | | D-2-hydroxyacid dehydrogenase | 0.61 | HGI48_RS20445 | | DNA-binding transcriptional regulator CytR | low | > 71 |
| Pseudomonas sp. RS175 | 0.25 | PFR28_00714 | | Glyoxylate/hydroxypyruvate reductase A | 0.40 | PFR28_02584 | | HTH-type transcriptional repressor CytR | low | > 88 |
| Dickeya dianthicola ME23 | 0.24 | DZA65_RS19760 | | D-2-hydroxyacid dehydrogenase | 0.61 | DZA65_RS21490 | | DNA-binding transcriptional regulator CytR | low | > 75 |
| Pseudomonas fluorescens FW300-N2C3 | 0.24 | AO356_04410 | | hydroxyacid dehydrogenase | 0.40 | AO356_22285 | | LacI family transcriptional regulator | — | — |
| Paraburkholderia sabiae LMG 24235 | 0.23 | QEN71_RS32025 | | glyoxylate/hydroxypyruvate reductase A | 0.36 | QEN71_RS25305 | | LacI family DNA-binding transcriptional regulator | low | > 153 |
| Echinicola vietnamensis KMM 6221, DSM 17526 | 0.21 | Echvi_3471 | | Phosphoglycerate dehydrogenase and related dehydrogenases | 0.28 | Echvi_3495 | | Transcriptional regulators | low | > 79 |
| Paraburkholderia graminis OAS925 | 0.21 | ABIE53_005027 | | glyoxylate/hydroxypyruvate reductase A | 0.33 | ABIE53_001217 | | LacI family repressor for deo operon, udp, cdd, tsx, nupC, and nupG | low | > 113 |
| Bifidobacterium breve UCC2003 | 0.20 | BBR_RS17310 | | D-2-hydroxyacid dehydrogenase | 0.21 | BBR_RS19505 | | LacI family transcriptional regulator | low | > 34 |
| Serratia liquefaciens MT49 | 0.20 | IAI46_09955 | | glyoxylate/hydroxypyruvate reductase GhrA | 0.69 | IAI46_24560 | | DNA-binding transcriptional regulator CytR | low | > 87 |
| Lysobacter sp. OAE881 | 0.20 | ABIE51_RS10035 | | glyoxylate/hydroxypyruvate reductase A | 0.26 | ABIE51_RS10155 | | LacI family DNA-binding transcriptional regulator | low | > 62 |
| Paraburkholderia bryophila 376MFSha3.1 | 0.20 | H281DRAFT_06341 | | glyoxylate/hydroxypyruvate reductase A | 0.34 | H281DRAFT_00103 | | transcriptional regulator, LacI family | low | > 103 |
| Klebsiella michiganensis M5al | 0.20 | BWI76_RS21910 | | glyoxylate/hydroxypyruvate reductase A | 0.68 | BWI76_RS00765 | | DNA-binding transcriptional regulator CytR | low | > 92 |
| Enterobacter sp. TBS_079 | 0.19 | MPMX20_01715 | | Glyoxylate/hydroxypyruvate reductase A | 0.68 | MPMX20_04535 | | HTH-type transcriptional repressor CytR | low | > 85 |
| Klebsiella pneumoniae MKP103 | 0.19 | KDGMDA_18520 | | glyoxylate/hydroxypyruvate reductase GhrA | 0.67 | KDGMDA_09275 | | DNA-binding transcriptional regulator CytR | low | > 95 |
| Agrobacterium fabrum C58 | 0.17 | Atu5474 | | 2-hydroxyacid dehydrogenase | 0.40 | Atu4373 | | LacI family transcriptional regulator | low | > 89 |
| Phaeobacter inhibens DSM 17395 | 0.17 | PGA1_c26570 | | putative glyoxylate/hydroxypyruvate reductase A | 0.29 | PGA1_c07800 | | putative transcriptional regulator, lacI family | low | > 62 |
| Sinorhizobium meliloti 1021 | 0.17 | SMc02828 | | hydroxyacid dehydrogenase | 0.38 | SM_b20014 | | transcriptional regulator | low | > 103 |
| Pantoea agglomerans CFBP13505 P0401 | 0.17 | PagCFBP13505_RS01525 | | glyoxylate/hydroxypyruvate reductase A | 0.66 | PagCFBP13505_RS18480 | | DNA-binding transcriptional regulator CytR | low | > 74 |
| Dinoroseobacter shibae DFL-12 | 0.16 | Dshi_0590 | | D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding (RefSeq) | 0.24 | Dshi_2029 | | transcriptional regulator, LacI family (RefSeq) | low | > 64 |
| Rhizobium sp. OAE497 | 0.16 | ABIE40_RS00635 | | glyoxylate/hydroxypyruvate reductase A | 0.33 | ABIE40_RS16795 | | LacI family DNA-binding transcriptional regulator | low | > 107 |
Not shown: 32 genomes with orthologs for CSW01_01380 only; 40 genomes with orthologs for CSW01_13525 only