| Organism | Ratio1 | Gene1 | Name1 | Description1 | Ratio2 | Gene2 | Name2 | Description2 | Cofit | Rank |
| Vibrio cholerae E7946 ATCC 55056 | 1.0 | CSW01_04470 | | phosphoribosylformylglycinamidine synthase | 1.0 | CSW01_12725 | | aspartate carbamoyltransferase | 0.54 | 17 |
| Serratia liquefaciens MT49 | 0.76 | IAI46_19475 | | phosphoribosylformylglycinamidine synthase | 0.76 | IAI46_02275 | | aspartate carbamoyltransferase | 0.58 | 12 |
| Escherichia coli BL21 | 0.76 | ECD_02449 | | phosphoribosylformyl-glycineamide synthetase | 0.75 | ECD_04113 | | aspartate carbamoyltransferase, catalytic subunit | 0.89 | 7 |
| Escherichia coli BW25113 | 0.76 | b2557 | purL | phosphoribosylformylglycinamidine synthase (NCBI) | 0.75 | b4245 | pyrB | aspartate carbamoyltransferase catalytic subunit (NCBI) | 0.86 | 12 |
| Escherichia coli ECOR27 | 0.76 | NOLOHH_13145 | purL | phosphoribosylformylglycinamidine synthase | 0.76 | NOLOHH_04125 | pyrB | aspartate carbamoyltransferase | 0.97 | 3 |
| Escherichia coli HS(pFamp)R (ATCC 700891) | 0.76 | OHPLBJKB_01150 | | Phosphoribosylformylglycinamidine synthase | 0.75 | OHPLBJKB_03789 | | Aspartate carbamoyltransferase catalytic subunit | 0.75 | 1 |
| Escherichia fergusonii Becca | 0.76 | EFB2_01339 | | Phosphoribosylformylglycinamidine synthase | 0.75 | EFB2_04288 | | Aspartate carbamoyltransferase catalytic subunit | low | > 86 |
| Escherichia coli ECRC102 | 0.76 | NIAGMN_19240 | purL | phosphoribosylformylglycinamidine synthase | 0.75 | NIAGMN_09715 | pyrB | aspartate carbamoyltransferase | 0.90 | 14 |
| Escherichia coli ECRC98 | 0.76 | JDDGAC_25135 | purL | phosphoribosylformylglycinamidine synthase | 0.75 | JDDGAC_15505 | pyrB | aspartate carbamoyltransferase | low | > 87 |
| Escherichia coli ECRC99 | 0.76 | KEDOAH_06750 | purL | phosphoribosylformylglycinamidine synthase | 0.75 | KEDOAH_16290 | pyrB | aspartate carbamoyltransferase | — | — |
| Escherichia coli ECRC100 | 0.76 | OKFHMN_21470 | purL | phosphoribosylformylglycinamidine synthase | 0.75 | OKFHMN_11865 | pyrB | aspartate carbamoyltransferase | 0.90 | 15 |
| Escherichia coli ECRC101 | 0.76 | MCAODC_12000 | purL | phosphoribosylformylglycinamidine synthase | 0.75 | MCAODC_02370 | pyrB | aspartate carbamoyltransferase | low | > 88 |
| Escherichia coli ECRC62 | 0.76 | BNILDI_11945 | purL | phosphoribosylformylglycinamidine synthase | 0.75 | BNILDI_07385 | pyrB | aspartate carbamoyltransferase | 0.96 | 9 |
| Escherichia coli Nissle 1917 | 0.76 | ECOLIN_RS14470 | | phosphoribosylformylglycinamidine synthase | 0.75 | ECOLIN_RS24625 | | aspartate carbamoyltransferase | 0.81 | 7 |
| Enterobacter asburiae PDN3 | 0.76 | EX28DRAFT_0092 | | phosphoribosylformylglycinamidine synthase, single chain form | 0.74 | EX28DRAFT_3446 | | aspartate carbamoyltransferase (EC 2.1.3.2) | — | — |
| Escherichia coli ECOR38 | 0.76 | HEPCGN_20615 | purL | phosphoribosylformylglycinamidine synthase | 0.75 | HEPCGN_10060 | pyrB | aspartate carbamoyltransferase | 0.90 | 16 |
| Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 | 0.75 | GFF2459 | | Phosphoribosylformylglycinamidine synthase, synthetase subunit (EC 6.3.5.3) / Phosphoribosylformylglycinamidine synthase, glutamine amidotransferase subunit (EC 6.3.5.3) | 0.75 | GFF930 | | Aspartate carbamoyltransferase (EC 2.1.3.2) | low | > 78 |
| Enterobacter sp. TBS_079 | 0.75 | MPMX20_03426 | | Phosphoribosylformylglycinamidine synthase | 0.74 | MPMX20_00544 | | Aspartate carbamoyltransferase catalytic subunit | 0.87 | 21 |
| Klebsiella pneumoniae MKP103 | 0.75 | KDGMDA_28395 | | phosphoribosylformylglycinamidine synthase | 0.76 | KDGMDA_11465 | | aspartate carbamoyltransferase | low | > 95 |
| Rahnella sp. WP5 | 0.75 | EX31_RS21895 | | phosphoribosylformylglycinamidine synthase | 0.74 | EX31_RS12785 | | aspartate carbamoyltransferase | 0.90 | 49 |
| Pantoea agglomerans CFBP13505 P0401 | 0.75 | PagCFBP13505_RS14820 | | phosphoribosylformylglycinamidine synthase | 0.75 | PagCFBP13505_RS08955 | | aspartate carbamoyltransferase | low | > 74 |
| Pantoea sp. MT58 | 0.75 | IAI47_04930 | | phosphoribosylformylglycinamidine synthase | 0.74 | IAI47_16860 | | aspartate carbamoyltransferase | 0.98 | 5 |
| Erwinia amylovora T8 | 0.75 | OLJFJH_10305 | | phosphoribosylformylglycinamidine synthase | 0.75 | OLJFJH_07330 | | aspartate carbamoyltransferase | 0.65 | 55 |
| Dickeya dadantii 3937 | 0.75 | DDA3937_RS15655 | | phosphoribosylformylglycinamidine synthase | 0.75 | DDA3937_RS01925 | | aspartate carbamoyltransferase | 0.83 | 16 |
| Klebsiella michiganensis M5al | 0.74 | BWI76_RS21265 | | phosphoribosylformylglycinamidine synthase | 0.76 | BWI76_RS02995 | | aspartate carbamoyltransferase | 0.60 | 81 |
| Dickeya dianthicola ME23 | 0.74 | DZA65_RS16830 | | phosphoribosylformylglycinamidine synthase | 0.75 | DZA65_RS01970 | | aspartate carbamoyltransferase | 0.61 | 61 |
| Dickeya dianthicola 67-19 | 0.74 | HGI48_RS15750 | | phosphoribosylformylglycinamidine synthase | 0.75 | HGI48_RS01900 | | aspartate carbamoyltransferase | 0.83 | 8 |
| Pectobacterium carotovorum WPP14 | 0.74 | HER17_RS05910 | | phosphoribosylformylglycinamidine synthase | 0.73 | HER17_RS19510 | | aspartate carbamoyltransferase | 0.93 | 19 |
| Shewanella oneidensis MR-1 | 0.73 | SO3287 | purL | phosphoribosylformylglycinamidine synthase (NCBI ptt file) | 0.34 | SO1301 | pyrB | aspartate carbamoyltransferase (NCBI ptt file) | 0.85 | 42 |
| Erwinia tracheiphila HP pepo 2.2 | 0.73 | IJEDHG_02970 | | Phosphoribosylformylglycinamidine synthase | 0.74 | IJEDHG_14060 | pyrB | aspartate carbamoyltransferase | 0.95 | 5 |
| Shewanella sp. ANA-3 | 0.73 | Shewana3_1240 | | phosphoribosylformylglycinamidine synthase (RefSeq) | 0.34 | Shewana3_3070 | | aspartate carbamoyltransferase (RefSeq) | 0.86 | 51 |
| Erwinia tracheiphila SCR3 | 0.73 | LU632_RS17975 | purL | phosphoribosylformylglycinamidine synthase | 0.74 | LU632_RS20950 | pyrB | aspartate carbamoyltransferase | 0.97 | 5 |
| Shewanella amazonensis SB2B | 0.72 | Sama_2350 | | phosphoribosylformylglycinamidine synthase (RefSeq) | 0.33 | Sama_0840 | | aspartate carbamoyltransferase (RefSeq) | low | > 62 |
| Shewanella loihica PV-4 | 0.72 | Shew_1301 | | phosphoribosylformylglycinamidine synthase (RefSeq) | 0.33 | Shew_1013 | | aspartate carbamoyltransferase (RefSeq) | 0.88 | 15 |
| Alteromonas macleodii MIT1002 | 0.71 | MIT1002_01027 | | Phosphoribosylformylglycinamidine synthase | 0.33 | MIT1002_00423 | | Aspartate carbamoyltransferase catalytic chain | 0.82 | 59 |
| Pseudomonas aeruginosa PA14 | 0.67 | IKLFDK_19210 | | phosphoribosylformylglycinamidine synthase | 0.23 | IKLFDK_23410 | | aspartate carbamoyltransferase catalytic subunit | low | > 100 |
| Pseudomonas sp. SVBP6 | 0.67 | COO64_RS04695 | purL | phosphoribosylformylglycinamidine synthase | 0.24 | COO64_RS13575 | | aspartate carbamoyltransferase catalytic subunit | 0.90 | 13 |
| Pseudomonas putida KT2440 | 0.67 | PP_1037 | | Phosphoribosylformylglycinamidine synthase | 0.24 | PP_4998 | | Aspartate carbamoyltransferase | — | — |
| Pseudomonas sp. BP01 | 0.67 | JOY50_RS11525 | purL | phosphoribosylformylglycinamidine synthase | 0.24 | JOY50_RS09700 | | aspartate carbamoyltransferase catalytic subunit | 0.53 | 8 |
| Pseudomonas segetis P6 | 0.67 | MPMX49_01557 | | Phosphoribosylformylglycinamidine synthase | 0.23 | MPMX49_00620 | | Aspartate carbamoyltransferase | — | — |
| Pseudomonas stutzeri RCH2 | 0.67 | Psest_3159 | | phosphoribosylformylglycinamidine synthase, single chain form | 0.24 | Psest_0291 | | aspartate carbamoyltransferase | — | — |
| Pseudomonas sp. S08-1 | 0.67 | OH686_17630 | | phosphoribosylformylglycinamidine synthase | 0.23 | OH686_10940 | | aspartate carbamoyltransferase | — | — |
| Pseudomonas syringae pv. syringae B728a ΔmexB | 0.67 | Psyr_1269 | | phosphoribosylformylglycinamidine synthase | 0.23 | Psyr_0482 | | aspartate carbamoyltransferase | — | — |
| Pseudomonas syringae pv. syringae B728a | 0.67 | Psyr_1269 | | phosphoribosylformylglycinamidine synthase | 0.23 | Psyr_0482 | | aspartate carbamoyltransferase | — | — |
| Pseudomonas simiae WCS417 | 0.67 | PS417_23020 | | phosphoribosylformylglycinamidine synthase | 0.24 | PS417_26700 | | aspartate carbamoyltransferase catalytic subunit | — | — |
| Pseudomonas fluorescens SBW25 | 0.66 | PFLU_RS24685 | | phosphoribosylformylglycinamidine synthase | 0.24 | PFLU_RS28345 | | aspartate carbamoyltransferase | — | — |
| Pseudomonas fluorescens SBW25-INTG | 0.66 | PFLU_RS24685 | | phosphoribosylformylglycinamidine synthase | 0.24 | PFLU_RS28345 | | aspartate carbamoyltransferase | — | — |
| Pseudomonas sp. DMC3 | 0.66 | GFF1962 | | Phosphoribosylformylglycinamidine synthase | 0.25 | GFF204 | | Aspartate carbamoyltransferase | — | — |
| Pseudomonas sp. RS175 | 0.66 | PFR28_03518 | | Phosphoribosylformylglycinamidine synthase | 0.25 | PFR28_04237 | | Aspartate carbamoyltransferase | — | — |
| Pseudomonas lactucae CFBP13502 | 0.66 | GEMAOFIL_04757 | | Phosphoribosylformylglycinamidine synthase | 0.24 | GEMAOFIL_05477 | | Aspartate carbamoyltransferase | — | — |
| Pseudomonas fluorescens FW300-N2C3 | 0.66 | AO356_17520 | | phosphoribosylformylglycinamidine synthase | 0.25 | AO356_13450 | | aspartate carbamoyltransferase catalytic subunit | — | — |
| Pseudomonas fluorescens FW300-N1B4 | 0.66 | Pf1N1B4_887 | | Phosphoribosylformylglycinamidine synthase, synthetase subunit (EC 6.3.5.3) / Phosphoribosylformylglycinamidine synthase, glutamine amidotransferase subunit (EC 6.3.5.3) | 0.25 | Pf1N1B4_2347 | | Aspartate carbamoyltransferase (EC 2.1.3.2) | — | — |
| Pseudomonas fluorescens FW300-N2E2 | 0.66 | Pf6N2E2_5432 | | Phosphoribosylformylglycinamidine synthase, synthetase subunit (EC 6.3.5.3) / Phosphoribosylformylglycinamidine synthase, glutamine amidotransferase subunit (EC 6.3.5.3) | 0.25 | Pf6N2E2_4606 | | Aspartate carbamoyltransferase (EC 2.1.3.2) | — | — |
| Pseudomonas fluorescens FW300-N2E3 | 0.66 | AO353_04485 | | phosphoribosylformylglycinamidine synthase | 0.25 | AO353_08135 | | aspartate carbamoyltransferase catalytic subunit | — | — |
| Pseudomonas fluorescens GW456-L13 | 0.66 | PfGW456L13_4835 | | Phosphoribosylformylglycinamidine synthase, synthetase subunit (EC 6.3.5.3) / Phosphoribosylformylglycinamidine synthase, glutamine amidotransferase subunit (EC 6.3.5.3) | 0.25 | PfGW456L13_1016 | | Aspartate carbamoyltransferase (EC 2.1.3.2) | — | — |
| Marinobacter adhaerens HP15 | 0.65 | HP15_1239 | | phosphoribosylformylglycinamidine synthase | 0.24 | HP15_3507 | | aspartate carbamoyltransferase | — | — |
| Kangiella aquimarina DSM 16071 | 0.64 | B158DRAFT_2244 | | phosphoribosylformylglycinamidine synthase, single chain form | 0.34 | B158DRAFT_0021 | | aspartate carbamoyltransferase (EC 2.1.3.2) | — | — |
| Methylophilus sp. DMC18 | 0.62 | GFF809 | | Phosphoribosylformylglycinamidine synthase | 0.23 | GFF868 | | Aspartate carbamoyltransferase | — | — |
| Herbaspirillum seropedicae SmR1 | 0.58 | HSERO_RS11190 | | phosphoribosylformylglycinamidine synthase | 0.22 | HSERO_RS02330 | | aspartate carbamoyltransferase | — | — |
| Cupriavidus basilensis FW507-4G11 | 0.57 | RR42_RS09140 | | phosphoribosylformylglycinamidine synthase | 0.23 | RR42_RS15860 | | aspartate carbamoyltransferase catalytic subunit | — | — |
| Dechlorosoma suillum PS | 0.56 | Dsui_2892 | | phosphoribosylformylglycinamidine synthase, single chain form | 0.23 | Dsui_0596 | | aspartate carbamoyltransferase | — | — |
| Acinetobacter baumannii LAC-4 | 0.56 | RR41_RS04700 | | phosphoribosylformylglycinamidine synthase | 0.23 | RR41_RS10085 | | aspartate carbamoyltransferase catalytic subunit | — | — |
| Acinetobacter radioresistens SK82 | 0.56 | MPMX26_02183 | | Phosphoribosylformylglycinamidine synthase | 0.23 | MPMX26_01099 | | Aspartate carbamoyltransferase | low | > 36 |
| Ralstonia solanacearum PSI07 | 0.54 | RPSI07_RS16190 | | phosphoribosylformylglycinamidine synthase | 0.22 | RPSI07_RS20635 | | aspartate carbamoyltransferase catalytic subunit | — | — |
| Ralstonia solanacearum GMI1000 | 0.54 | RS_RS08710 | | phosphoribosylformylglycinamidine synthase | 0.22 | RS_RS03410 | | aspartate carbamoyltransferase | — | — |
| Ralstonia sp. UNC404CL21Col | 0.54 | ABZR87_RS12730 | | phosphoribosylformylglycinamidine synthase | 0.22 | ABZR87_RS08625 | | aspartate carbamoyltransferase catalytic subunit | — | — |
| Ralstonia solanacearum IBSBF1503 | 0.53 | RALBFv3_RS01285 | | phosphoribosylformylglycinamidine synthase | 0.22 | RALBFv3_RS12625 | | aspartate carbamoyltransferase catalytic subunit | — | — |
| Ralstonia solanacearum UW163 | 0.53 | UW163_RS14595 | | phosphoribosylformylglycinamidine synthase | 0.22 | UW163_RS00940 | | aspartate carbamoyltransferase catalytic subunit | — | — |
| Rhodanobacter sp. FW510-T8 | 0.53 | OKGIIK_11505 | purL | phosphoribosylformylglycinamidine synthase | 0.22 | OKGIIK_11095 | pyrB | aspartate carbamoyltransferase catalytic subunit | — | — |
| Rhodanobacter denitrificans MT42 | 0.53 | LRK55_RS04500 | | phosphoribosylformylglycinamidine synthase | 0.23 | LRK55_RS03990 | | aspartate carbamoyltransferase catalytic subunit | — | — |
| Rhodanobacter denitrificans FW104-10B01 | 0.53 | LRK54_RS04720 | | phosphoribosylformylglycinamidine synthase | 0.23 | LRK54_RS04220 | | aspartate carbamoyltransferase catalytic subunit | — | — |
| Dyella japonica UNC79MFTsu3.2 | 0.53 | ABZR86_RS19235 | | phosphoribosylformylglycinamidine synthase | 0.24 | ABZR86_RS10390 | | aspartate carbamoyltransferase catalytic subunit | — | — |
| Hydrogenophaga sp. GW460-11-11-14-LB1 | 0.52 | GFF4566 | | Phosphoribosylformylglycinamidine synthase, synthetase subunit (EC 6.3.5.3) / Phosphoribosylformylglycinamidine synthase, glutamine amidotransferase subunit (EC 6.3.5.3) | 0.21 | GFF651 | | Aspartate carbamoyltransferase (EC 2.1.3.2) | — | — |
| Rhodanobacter sp000427505 FW510-R12 | 0.52 | LRK53_RS05295 | | phosphoribosylformylglycinamidine synthase | 0.23 | LRK53_RS05705 | | aspartate carbamoyltransferase catalytic subunit | — | — |
| Acidovorax sp. GW101-3H11 | 0.52 | Ac3H11_539 | | Phosphoribosylformylglycinamidine synthase, synthetase subunit (EC 6.3.5.3) / Phosphoribosylformylglycinamidine synthase, glutamine amidotransferase subunit (EC 6.3.5.3) | 0.21 | Ac3H11_3978 | | Aspartate carbamoyltransferase (EC 2.1.3.2) | — | — |
| Lysobacter sp. OAE881 | 0.49 | ABIE51_RS04505 | | phosphoribosylformylglycinamidine synthase | 0.24 | ABIE51_RS16015 | | aspartate carbamoyltransferase catalytic subunit | low | > 62 |
| Xanthomonas campestris pv. campestris strain 8004 | 0.49 | Xcc-8004.4439.1 | | Phosphoribosylformylglycinamidine synthase, synthetase subunit (EC 6.3.5.3) / Phosphoribosylformylglycinamidine synthase, glutamine amidotransferase subunit (EC 6.3.5.3) | 0.25 | Xcc-8004.1722.1 | | Aspartate carbamoyltransferase (EC 2.1.3.2) | — | — |
| Pedobacter sp. GW460-11-11-14-LB5 | 0.26 | CA265_RS05195 | | phosphoribosylformylglycinamidine synthase | 0.24 | CA265_RS14660 | | aspartate carbamoyltransferase | — | — |
| Echinicola vietnamensis KMM 6221, DSM 17526 | 0.26 | Echvi_4428 | | Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain | 0.23 | Echvi_4661 | | aspartate carbamoyltransferase | — | — |
| Cellulophaga baltica 18 | 0.26 | M666_RS18255 | | phosphoribosylformylglycinamidine synthase | 0.24 | M666_RS11460 | | aspartate carbamoyltransferase catalytic subunit | low | > 67 |
| Parabacteroides merdae CL09T00C40 | 0.26 | HMPREF1078_RS04325 | | phosphoribosylformylglycinamidine synthase | 0.51 | HMPREF1078_RS01350 | | aspartate carbamoyltransferase | — | — |
| Phocaeicola dorei CL03T12C01 | 0.25 | ABI39_RS00405 | | phosphoribosylformylglycinamidine synthase | 0.50 | ABI39_RS17400 | | aspartate carbamoyltransferase | — | — |
| Phocaeicola vulgatus CL09T03C04 | 0.25 | HMPREF1058_RS07955 | | phosphoribosylformylglycinamidine synthase | 0.50 | HMPREF1058_RS03820 | | aspartate carbamoyltransferase | — | — |
| Bacteroides thetaiotaomicron VPI-5482 | 0.25 | BT1733 | | putative phosphoribosylformylglycinamidine synthase (NCBI ptt file) | 0.50 | BT0742 | | aspartate carbamoyltransferase catalytic chain (NCBI ptt file) | — | — |
| Bacteroides stercoris CC31F | 0.25 | HMPREF1181_RS05605 | | phosphoribosylformylglycinamidine synthase | 0.51 | HMPREF1181_RS14990 | | aspartate carbamoyltransferase | 0.91 | 7 |
| Bacteroides ovatus ATCC 8483 | 0.25 | BACOVA_04462 | | putative phosphoribosylformylglycinamidine synthase | 0.50 | BACOVA_02450 | | aspartate carbamoyltransferase | — | — |
| Bifidobacterium breve UCC2003 | 0.07 | BBR_RS13445 | | phosphoribosylformylglycinamidine synthase | 0.42 | BBR_RS15425 | | aspartate carbamoyltransferase | low | > 34 |
| Fusobacterium nucleatum SB010 | 0.07 | HUW76_05155 | | phosphoribosylformylglycinamidine synthase | 0.23 | HUW76_08765 | | aspartate carbamoyltransferase catalytic subunit | 0.94 | 35 |
Not shown: 7 genomes with orthologs for CSW01_04470 only; 21 genomes with orthologs for CSW01_12725 only