Conservation of cofitness between CSW01_00680 and CSW01_11570 in Vibrio cholerae E7946 ATCC 55056

43 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Vibrio cholerae E7946 ATCC 55056 1.0 CSW01_00680 Cof-type HAD-IIB family hydrolase 1.0 CSW01_11570 glutamate-5-semialdehyde dehydrogenase 0.39 11
Pantoea agglomerans CFBP13505 P0401 0.50 PagCFBP13505_RS15315 sugar/pyridoxal phosphate phosphatase YigL 0.57 PagCFBP13505_RS10045 glutamate-5-semialdehyde dehydrogenase — —
Pectobacterium carotovorum WPP14 0.50 HER17_RS01415 sugar/pyridoxal phosphate phosphatase YigL 0.60 HER17_RS04705 glutamate-5-semialdehyde dehydrogenase low > 75
Pantoea sp. MT58 0.50 IAI47_18335 sugar/pyridoxal phosphate phosphatase YigL 0.57 IAI47_15115 glutamate-5-semialdehyde dehydrogenase low > 76
Serratia liquefaciens MT49 0.50 IAI46_00790 sugar/pyridoxal phosphate phosphatase YigL 0.61 IAI46_04435 glutamate-5-semialdehyde dehydrogenase low > 86
Klebsiella pneumoniae MKP103 0.49 KDGMDA_09760 sugar/pyridoxal phosphate phosphatase YigL 0.59 KDGMDA_14000 glutamate-5-semialdehyde dehydrogenase low > 95
Dickeya dadantii 3937 0.49 DDA3937_RS19825 sugar/pyridoxal phosphate phosphatase YigL 0.62 DDA3937_RS16530 glutamate-5-semialdehyde dehydrogenase low > 74
Dickeya dianthicola ME23 0.49 DZA65_RS21025 sugar/pyridoxal phosphate phosphatase YigL 0.61 DZA65_RS17690 glutamate-5-semialdehyde dehydrogenase low > 75
Dickeya dianthicola 67-19 0.49 HGI48_RS19980 sugar/pyridoxal phosphate phosphatase YigL 0.62 HGI48_RS16600 glutamate-5-semialdehyde dehydrogenase low > 71
Rahnella sp. WP5 0.49 EX31_RS15230 sugar/pyridoxal phosphate phosphatase YigL 0.60 EX31_RS20975 glutamate-5-semialdehyde dehydrogenase low > 89
Klebsiella michiganensis M5al 0.49 BWI76_RS01265 sugar/pyridoxal phosphate phosphatase YigL 0.60 BWI76_RS05835 gamma-glutamyl-phosphate reductase low > 92
Escherichia coli ECRC101 0.48 MCAODC_04845 yigL sugar/pyridoxal phosphate phosphatase YigL 0.58 MCAODC_00190 proA glutamate-5-semialdehyde dehydrogenase low > 88
Escherichia coli ECRC62 0.48 BNILDI_05060 yigL sugar/pyridoxal phosphate phosphatase YigL 0.58 BNILDI_00240 proA glutamate-5-semialdehyde dehydrogenase low > 75
Escherichia coli ECRC98 0.48 JDDGAC_17965 yigL sugar/pyridoxal phosphate phosphatase YigL 0.58 JDDGAC_13295 proA glutamate-5-semialdehyde dehydrogenase low > 87
Escherichia coli ECRC99 0.48 KEDOAH_13810 yigL sugar/pyridoxal phosphate phosphatase YigL 0.58 KEDOAH_18485 proA glutamate-5-semialdehyde dehydrogenase — —
Escherichia coli HS(pFamp)R (ATCC 700891) 0.48 OHPLBJKB_04225 Pyridoxal phosphate phosphatase YigL 0.58 OHPLBJKB_03397 Gamma-glutamyl phosphate reductase 0.35 24
Escherichia coli BW25113 0.48 b3826 yigL predicted hydrolase (NCBI) 0.58 b0243 proA gamma-glutamyl phosphate reductase (NCBI) low > 76
Escherichia coli Nissle 1917 0.48 ECOLIN_RS21965 sugar/pyridoxal phosphate phosphatase YigL 0.58 ECOLIN_RS01830 glutamate-5-semialdehyde dehydrogenase — —
Escherichia coli ECOR38 0.48 HEPCGN_13040 yigL sugar/pyridoxal phosphate phosphatase YigL 0.58 HEPCGN_07775 proA glutamate-5-semialdehyde dehydrogenase low > 88
Escherichia coli ECOR27 0.48 NOLOHH_06470 yigL sugar/pyridoxal phosphate phosphatase YigL 0.58 NOLOHH_02045 proA glutamate-5-semialdehyde dehydrogenase low > 76
Escherichia coli ECRC100 0.48 OKFHMN_14340 yigL sugar/pyridoxal phosphate phosphatase YigL 0.58 OKFHMN_09670 proA glutamate-5-semialdehyde dehydrogenase low > 79
Escherichia coli ECRC102 0.48 NIAGMN_12095 yigL sugar/pyridoxal phosphate phosphatase YigL 0.58 NIAGMN_07530 proA glutamate-5-semialdehyde dehydrogenase low > 80
Escherichia coli BL21 0.48 ECD_03705 pyridoxal phosphate phosphatase 0.58 ECD_00240 gamma-glutamylphosphate reductase low > 61
Escherichia fergusonii Becca 0.48 EFB2_04811 Pyridoxal phosphate phosphatase YigL 0.57 EFB2_03777 Gamma-glutamyl phosphate reductase low > 86
Erwinia tracheiphila SCR3 0.48 LU632_RS24075 yigL sugar/pyridoxal phosphate phosphatase YigL 0.59 LU632_RS01190 proA glutamate-5-semialdehyde dehydrogenase low > 74
Erwinia tracheiphila HP pepo 2.2 0.48 IJEDHG_08715 yigL sugar/pyridoxal phosphate phosphatase YigL 0.59 IJEDHG_15495 proA glutamate-5-semialdehyde dehydrogenase low > 61
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.47 GFF252 Cof protein, HD superfamily hydrolase 0.58 GFF4115 Gamma-glutamyl phosphate reductase (EC 1.2.1.41) low > 78
Enterobacter asburiae PDN3 0.47 EX28DRAFT_4491 HAD-superfamily hydrolase, subfamily IIB 0.58 EX28DRAFT_2650 glutamate-5-semialdehyde dehydrogenase (EC 1.2.1.41) low > 76
Enterobacter sp. TBS_079 0.47 MPMX20_04454 Pyridoxal phosphate phosphatase YigL 0.58 MPMX20_00928 Gamma-glutamyl phosphate reductase low > 85
Erwinia amylovora T8 0.46 OLJFJH_06460 sugar/pyridoxal phosphate phosphatase YigL 0.59 OLJFJH_18405 glutamate-5-semialdehyde dehydrogenase low > 58
Paraburkholderia sabiae LMG 24235 0.37 QEN71_RS29060 Cof-type HAD-IIB family hydrolase 0.40 QEN71_RS26940 glutamate-5-semialdehyde dehydrogenase low > 153
Burkholderia phytofirmans PsJN 0.37 BPHYT_RS19055 COF family hydrolase 0.38 BPHYT_RS16770 gamma-glutamyl phosphate reductase — —
Paraburkholderia graminis OAS925 0.37 ABIE53_000135 Cof subfamily protein (haloacid dehalogenase superfamily) 0.37 ABIE53_003523 glutamate-5-semialdehyde dehydrogenase low > 113
Paraburkholderia bryophila 376MFSha3.1 0.35 H281DRAFT_05732 hypothetical protein 0.38 H281DRAFT_06324 glutamate-5-semialdehyde dehydrogenase low > 103
Pseudomonas sp. DMC3 0.17 GFF3449 Sugar phosphatase YidA 0.38 GFF3876 Gamma-glutamyl phosphate reductase low > 89
Pseudomonas fluorescens SBW25-INTG 0.17 PFLU_RS13145 Cof-type HAD-IIB family hydrolase 0.41 PFLU_RS26675 glutamate-5-semialdehyde dehydrogenase — —
Pseudomonas fluorescens SBW25 0.17 PFLU_RS13145 Cof-type HAD-IIB family hydrolase 0.41 PFLU_RS26675 glutamate-5-semialdehyde dehydrogenase — —
Pseudomonas simiae WCS417 0.17 PS417_12455 hydrolase 0.41 PS417_24745 gamma-glutamyl phosphate reductase low > 88
Pseudomonas lactucae CFBP13502 0.17 GEMAOFIL_02738 Pyridoxal phosphate phosphatase YigL 0.41 GEMAOFIL_05102 Gamma-glutamyl phosphate reductase — —
Pseudomonas fluorescens FW300-N1B4 0.16 Pf1N1B4_4727 HMP-PP hydrolase (pyridoxal phosphatase) Cof, detected in genetic screen for thiamin metabolic genes (PMID:15292217) 0.38 Pf1N1B4_2688 Gamma-glutamyl phosphate reductase (EC 1.2.1.41) low > 87
Parabacteroides merdae CL09T00C40 0.16 HMPREF1078_RS07825 Cof-type HAD-IIB family hydrolase 0.36 HMPREF1078_RS10655 glutamate-5-semialdehyde dehydrogenase low > 61
Pseudomonas fluorescens FW300-N2C3 0.15 AO356_27845 hydrolase 0.37 AO356_15290 gamma-glutamyl phosphate reductase low > 104
Pseudomonas fluorescens FW300-N2E2 0.14 Pf6N2E2_759 HMP-PP hydrolase (pyridoxal phosphatase) Cof, detected in genetic screen for thiamin metabolic genes (PMID:15292217) 0.38 Pf6N2E2_4993 Gamma-glutamyl phosphate reductase (EC 1.2.1.41) low > 103
Cellulophaga baltica 18 0.11 M666_RS10120 HAD family hydrolase 0.29 M666_RS02645 glutamate-5-semialdehyde dehydrogenase low > 67

Not shown: 1 genomes with orthologs for CSW01_00680 only; 74 genomes with orthologs for CSW01_11570 only