| Organism | Ratio1 | Gene1 | Name1 | Description1 | Ratio2 | Gene2 | Name2 | Description2 | Cofit | Rank |
| Vibrio cholerae E7946 ATCC 55056 | 1.0 | CSW01_02425 | | YggW family oxidoreductase | 1.0 | CSW01_10355 | | phosphohistidine phosphatase SixA | 0.52 | 18 |
| Pectobacterium carotovorum WPP14 | 0.69 | HER17_RS03785 | | radical SAM family heme chaperone HemW | 0.33 | HER17_RS06920 | | phosphohistidine phosphatase SixA | low | > 75 |
| Dickeya dadantii 3937 | 0.68 | DDA3937_RS17325 | | radical SAM family heme chaperone HemW | 0.34 | DDA3937_RS14595 | | phosphohistidine phosphatase SixA | low | > 74 |
| Dickeya dianthicola 67-19 | 0.68 | HGI48_RS17370 | | radical SAM family heme chaperone HemW | 0.34 | HGI48_RS14545 | | phosphohistidine phosphatase SixA | low | > 71 |
| Dickeya dianthicola ME23 | 0.68 | DZA65_RS18460 | | radical SAM family heme chaperone HemW | 0.34 | DZA65_RS15480 | | phosphohistidine phosphatase SixA | low | > 75 |
| Serratia liquefaciens MT49 | 0.68 | IAI46_21435 | | radical SAM family heme chaperone HemW | 0.31 | IAI46_18040 | | phosphohistidine phosphatase SixA | low | > 86 |
| Escherichia coli ECRC102 | 0.67 | NIAGMN_17000 | hemW | radical SAM family heme chaperone HemW | 0.30 | NIAGMN_20340 | sixA | phosphohistidine phosphatase SixA | low | > 80 |
| Escherichia coli ECRC100 | 0.67 | OKFHMN_19235 | hemW | radical SAM family heme chaperone HemW | 0.30 | OKFHMN_22565 | sixA | phosphohistidine phosphatase SixA | low | > 79 |
| Escherichia coli ECRC101 | 0.67 | MCAODC_09755 | hemW | radical SAM family heme chaperone HemW | 0.30 | MCAODC_13595 | sixA | phosphohistidine phosphatase SixA | low | > 88 |
| Escherichia coli ECRC98 | 0.67 | JDDGAC_22865 | hemW | radical SAM family heme chaperone HemW | 0.30 | JDDGAC_26525 | sixA | phosphohistidine phosphatase SixA | — | — |
| Escherichia coli ECRC99 | 0.67 | KEDOAH_08905 | hemW | radical SAM family heme chaperone HemW | 0.30 | KEDOAH_05630 | sixA | phosphohistidine phosphatase SixA | — | — |
| Escherichia fergusonii Becca | 0.66 | EFB2_00947 | | Heme chaperone HemW | 0.30 | EFB2_01519 | | Phosphohistidine phosphatase SixA | low | > 86 |
| Escherichia coli BW25113 | 0.66 | b2955 | yggW | coproporphyrinogen III oxidase (NCBI) | 0.30 | b2340 | sixA | phosphohistidine phosphatase (NCBI) | low | > 76 |
| Escherichia coli HS(pFamp)R (ATCC 700891) | 0.66 | OHPLBJKB_00761 | | Oxygen-independent coproporphyrinogen-III oxidase-like protein YqeR | 0.30 | OHPLBJKB_01366 | | Phosphohistidine phosphatase SixA | low | > 74 |
| Escherichia coli BL21 | 0.66 | ECD_02785 | | HemN family putative oxidoreductase | 0.30 | ECD_02264 | | phosphohistidine phosphatase | — | — |
| Escherichia coli ECRC62 | 0.66 | BNILDI_09685 | hemW | radical SAM family heme chaperone HemW | 0.30 | BNILDI_13115 | sixA | phosphohistidine phosphatase SixA | low | > 75 |
| Erwinia tracheiphila HP pepo 2.2 | 0.66 | IJEDHG_03465 | hemW | radical SAM family heme chaperone HemW | 0.32 | IJEDHG_17810 | sixA | phosphohistidine phosphatase SixA | — | — |
| Erwinia tracheiphila SCR3 | 0.66 | LU632_RS05445 | hemW | radical SAM family heme chaperone HemW | 0.32 | LU632_RS07760 | sixA | phosphohistidine phosphatase SixA | — | — |
| Escherichia coli ECOR38 | 0.65 | HEPCGN_18540 | hemW | radical SAM family heme chaperone HemW | 0.30 | HEPCGN_21760 | sixA | phosphohistidine phosphatase SixA | low | > 88 |
| Escherichia coli Nissle 1917 | 0.65 | ECOLIN_RS16435 | | radical SAM family heme chaperone HemW | 0.30 | ECOLIN_RS13545 | | phosphohistidine phosphatase SixA | — | — |
| Escherichia coli ECOR27 | 0.65 | NOLOHH_11105 | hemW | radical SAM family heme chaperone HemW | 0.30 | NOLOHH_14200 | sixA | phosphohistidine phosphatase SixA | low | > 76 |
| Enterobacter sp. TBS_079 | 0.65 | MPMX20_03813 | | Heme chaperone HemW | 0.29 | MPMX20_03267 | | Phosphohistidine phosphatase SixA | low | > 85 |
| Pantoea agglomerans CFBP13505 P0401 | 0.65 | PagCFBP13505_RS16115 | | radical SAM family heme chaperone HemW | 0.35 | PagCFBP13505_RS00090 | | phosphohistidine phosphatase SixA | low | > 74 |
| Enterobacter asburiae PDN3 | 0.65 | EX28DRAFT_2993 | | putative oxygen-independent coproporphyrinogen III oxidase | 0.26 | EX28DRAFT_0272 | | phosphohistidine phosphatase, SixA | low | > 76 |
| Pantoea sp. MT58 | 0.65 | IAI47_03580 | | radical SAM family heme chaperone HemW | 0.35 | IAI47_06135 | | phosphohistidine phosphatase SixA | low | > 76 |
| Klebsiella michiganensis M5al | 0.65 | BWI76_RS24120 | | YggW family oxidoreductase | 0.31 | BWI76_RS20450 | | phosphohistidine phosphatase | — | — |
| Erwinia amylovora T8 | 0.64 | OLJFJH_08515 | | radical SAM family heme chaperone HemW | 0.33 | OLJFJH_11140 | | phosphohistidine phosphatase SixA | — | — |
| Rahnella sp. WP5 | 0.63 | EX31_RS02710 | | radical SAM family heme chaperone HemW | 0.30 | EX31_RS19700 | | phosphohistidine phosphatase SixA | 0.27 | 42 |
| Shewanella loihica PV-4 | 0.59 | Shew_1131 | | putative oxygen-independent coproporphyrinogen III oxidase (RefSeq) | 0.36 | Shew_2419 | | phosphohistidine phosphatase, SixA (RefSeq) | low | > 60 |
| Shewanella sp. ANA-3 | 0.59 | Shewana3_1188 | | putative oxygen-independent coproporphyrinogen III oxidase (RefSeq) | 0.37 | Shewana3_1466 | | phosphohistidine phosphatase, SixA (RefSeq) | low | > 73 |
| Shewanella oneidensis MR-1 | 0.59 | SO3359 | | oxygen-independent coproporphyrinogen III oxidase, putative (NCBI ptt file) | 0.37 | SO3082 | sixA | phosphohistidine phosphatase SixA (NCBI ptt file) | low | > 76 |
| Alteromonas macleodii MIT1002 | 0.59 | MIT1002_00939 | | Oxygen-independent coproporphyrinogen-III oxidase 1 | 0.28 | MIT1002_01292 | | Phosphohistidine phosphatase SixA | low | > 70 |
| Shewanella amazonensis SB2B | 0.56 | Sama_2483 | | oxygen-independent coproporphyrinogen III oxidase, putative (RefSeq) | 0.35 | Sama_2162 | | putative phosphohistidine phosphatase, SixA (RefSeq) | low | > 62 |
| Pseudomonas sp. RS175 | 0.54 | PFR28_04249 | | Heme chaperone HemW | 0.19 | PFR28_03074 | | hypothetical protein | low | > 88 |
| Kangiella aquimarina DSM 16071 | 0.54 | B158DRAFT_0201 | | coproporphyrinogen III oxidase, anaerobic (EC 1.3.99.22) | 0.16 | B158DRAFT_1295 | | phosphohistidine phosphatase, SixA | low | > 40 |
| Pseudomonas fluorescens FW300-N2E2 | 0.54 | Pf6N2E2_4593 | | Radical SAM family enzyme, similar to coproporphyrinogen III oxidase, oxygen-independent, clustered with nucleoside-triphosphatase RdgB | 0.20 | Pf6N2E2_5877 | | Phosphohistidine phosphatase SixA | low | > 103 |
| Pseudomonas fluorescens GW456-L13 | 0.53 | PfGW456L13_1003 | | Radical SAM family enzyme, similar to coproporphyrinogen III oxidase, oxygen-independent, clustered with nucleoside-triphosphatase RdgB | 0.22 | PfGW456L13_2048 | | Phosphohistidine phosphatase SixA | low | > 87 |
| Pseudomonas fluorescens FW300-N1B4 | 0.53 | Pf1N1B4_2334 | | Radical SAM family enzyme, similar to coproporphyrinogen III oxidase, oxygen-independent, clustered with nucleoside-triphosphatase RdgB | 0.21 | Pf1N1B4_3520 | | Phosphohistidine phosphatase SixA | low | > 87 |
| Pseudomonas fluorescens FW300-N2C3 | 0.53 | AO356_13390 | | coproporphyrinogen III oxidase | 0.17 | AO356_19805 | | phosphohistidine phosphatase | low | > 104 |
| Pseudomonas sp. S08-1 | 0.51 | OH686_11020 | | Oxygen-independent coproporphyrinogen-III oxidase-like protein YggW | 0.19 | OH686_00485 | | phosphohistidine phosphatase SixA | low | > 80 |
| Pseudomonas stutzeri RCH2 | 0.50 | Psest_0276 | | putative oxygen-independent coproporphyrinogen III oxidase | 0.21 | Psest_2469 | | phosphohistidine phosphatase SixA | — | — |
| Acinetobacter radioresistens SK82 | 0.41 | MPMX26_00308 | | Heme chaperone HemW | 0.18 | MPMX26_01117 | | hypothetical protein | low | > 36 |
| Agrobacterium fabrum C58 | 0.30 | Atu0325 | | oxygen-independent coproporphyrinogen III oxidase | 0.17 | Atu1358 | | hypothetical protein | — | — |
| Magnetospirillum magneticum AMB-1 | 0.27 | AMB_RS22770 | | radical SAM protein | 0.17 | AMB_RS14300 | | histidine phosphatase family protein | low | > 64 |
| Brevundimonas sp. GW460-12-10-14-LB2 | 0.26 | A4249_RS12445 | | radical SAM family heme chaperone HemW | 0.19 | A4249_RS00290 | | histidine phosphatase family protein | low | > 48 |
Not shown: 65 genomes with orthologs for CSW01_02425 only; 0 genomes with orthologs for CSW01_10355 only