Conservation of cofitness between CSW01_07735 and CSW01_10020 in Vibrio cholerae E7946 ATCC 55056

43 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Vibrio cholerae E7946 ATCC 55056 1.0 CSW01_07735 multidrug resistance protein NorM 1.0 CSW01_10020 ROK family protein 0.68 19
Pectobacterium carotovorum WPP14 0.55 HER17_RS09220 MATE family efflux transporter 0.50 HER17_RS10735 ROK family transcriptional regulator low > 75
Enterobacter sp. TBS_079 0.55 MPMX20_01973 Multidrug resistance protein MdtK 0.47 MPMX20_02063 Protein mlc low > 85
Serratia liquefaciens MT49 0.54 IAI46_11210 MATE family efflux transporter 0.50 IAI46_11685 ROK family transcriptional regulator low > 87
Klebsiella michiganensis M5al 0.54 BWI76_RS16535 MATE family efflux transporter 0.47 BWI76_RS15955 transcriptional regulator low > 92
Escherichia coli HS(pFamp)R (ATCC 700891) 0.54 OHPLBJKB_02061 Multidrug resistance protein MdtK 0.46 OHPLBJKB_02132 Protein mlc low > 74
Escherichia coli Nissle 1917 0.54 ECOLIN_RS09270 multidrug efflux MATE transporter MdtK 0.47 ECOLIN_RS08905 sugar metabolism global transcriptional regulator Mlc — —
Escherichia coli BW25113 0.54 b1663 mdtK multidrug efflux protein NorM (NCBI) 0.46 b1594 dgsA DNA-binding transcriptional repressor (NCBI) low > 76
Escherichia coli BL21 0.54 ECD_01634 multidrug efflux system transporter 0.46 ECD_01563 glucosamine anaerobic growth regulon transcriptional repressor; autorepressor — —
Escherichia fergusonii Becca 0.54 EFB2_02329 Multidrug resistance protein MdtK 0.47 EFB2_02398 Protein mlc low > 86
Escherichia coli ECRC98 0.54 JDDGAC_01950 mdtK multidrug efflux MATE transporter MdtK 0.47 JDDGAC_02330 mlc DNA-binding transcriptional repressor Mlc low > 87
Escherichia coli ECRC102 0.54 NIAGMN_00705 mdtK multidrug efflux MATE transporter MdtK 0.47 NIAGMN_00335 mlc DNA-binding transcriptional repressor Mlc low > 80
Escherichia coli ECRC99 0.54 KEDOAH_00750 mdtK multidrug efflux MATE transporter MdtK 0.47 KEDOAH_00365 mlc DNA-binding transcriptional repressor Mlc — —
Escherichia coli ECRC100 0.54 OKFHMN_27360 mdtK multidrug efflux MATE transporter MdtK 0.47 OKFHMN_27740 mlc DNA-binding transcriptional repressor Mlc low > 79
Escherichia coli ECRC101 0.54 MCAODC_18050 mdtK multidrug efflux MATE transporter MdtK 0.47 MCAODC_17670 mlc DNA-binding transcriptional repressor Mlc low > 87
Escherichia coli ECOR38 0.54 HEPCGN_05745 mdtK multidrug efflux MATE transporter MdtK 0.47 HEPCGN_06115 mlc DNA-binding transcriptional repressor Mlc low > 88
Rahnella sp. WP5 0.54 EX31_RS13855 MATE family efflux transporter 0.50 EX31_RS16985 ROK family transcriptional regulator low > 89
Escherichia coli ECRC62 0.54 BNILDI_16670 mdtK multidrug efflux MATE transporter MdtK 0.47 BNILDI_17035 mlc DNA-binding transcriptional repressor Mlc low > 75
Escherichia coli ECOR27 0.54 NOLOHH_17880 mdtK multidrug efflux MATE transporter MdtK 0.47 NOLOHH_18245 mlc DNA-binding transcriptional repressor Mlc low > 76
Klebsiella pneumoniae MKP103 0.54 KDGMDA_23495 MdtK family multidrug efflux MATE transporter 0.48 KDGMDA_21230 transcriptional regulator low > 95
Enterobacter asburiae PDN3 0.54 EX28DRAFT_1660 putative efflux protein, MATE family 0.48 EX28DRAFT_1493 Transcriptional regulator/sugar kinase low > 76
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.53 GFF3613 Multi antimicrobial extrusion protein (Na(+)/drug antiporter), MATE family of MDR efflux pumps 0.47 GFF1785 Mlc, transcriptional repressor of MalT (the transcriptional activator of maltose regulon) and manXYZ operon low > 78
Dickeya dianthicola 67-19 0.53 HGI48_RS12700 MATE family efflux transporter 0.49 HGI48_RS10675 ROK family transcriptional regulator low > 71
Dickeya dianthicola ME23 0.53 DZA65_RS13155 MATE family efflux transporter 0.49 DZA65_RS11145 ROK family transcriptional regulator 0.49 9
Erwinia amylovora T8 0.53 OLJFJH_14535 Multidrug resistance protein MdtK 0.48 OLJFJH_14275 transcriptional regulator low > 58
Pantoea sp. MT58 0.52 IAI47_10820 MATE family efflux transporter 0.45 IAI47_09750 ROK family transcriptional regulator low > 76
Pantoea agglomerans CFBP13505 P0401 0.52 PagCFBP13505_RS17770 MATE family efflux transporter 0.45 PagCFBP13505_RS06405 ROK family transcriptional regulator low > 74
Erwinia tracheiphila HP pepo 2.2 0.50 IJEDHG_25190 MATE family efflux transporter 0.47 IJEDHG_23280 transcriptional regulator low > 61
Erwinia tracheiphila SCR3 0.50 LU632_RS11170 MATE family efflux transporter 0.47 LU632_RS12305 ROK family transcriptional regulator low > 73
Dyella japonica UNC79MFTsu3.2 0.31 ABZR86_RS12525 MATE family efflux transporter 0.14 ABZR86_RS19180 ROK family transcriptional regulator low > 74
Pontibacter actiniarum KMM 6156, DSM 19842 0.25 CA264_06370 MATE family efflux transporter 0.20 CA264_08710 sugar kinase 0.34 27
Bacteroides thetaiotaomicron VPI-5482 0.20 BT3804 putative transport protein, multidrug efflux protein (NCBI ptt file) 0.17 BT0433 putative xylose repressor (NCBI ptt file) — —
Phocaeicola dorei CL03T12C01 0.20 ABI39_RS02110 MATE family efflux transporter 0.18 ABI39_RS21185 ROK family transcriptional regulator low > 72
Phocaeicola vulgatus CL09T03C04 0.20 HMPREF1058_RS02770 MATE family efflux transporter 0.18 HMPREF1058_RS07285 ROK family transcriptional regulator low > 67
Bacteroides stercoris CC31F 0.19 HMPREF1181_RS00200 MATE family efflux transporter 0.17 HMPREF1181_RS04110 ROK family transcriptional regulator low > 56
Sinorhizobium meliloti 1021 0.19 SMc01211 hypothetical protein 0.15 SMa2303 ROK family transcriptional regulator low > 103
Parabacteroides merdae CL09T00C40 0.19 HMPREF1078_RS10360 MATE family efflux transporter 0.19 HMPREF1078_RS06205 ROK family transcriptional regulator low > 61
Variovorax sp. OAS795 0.19 ABID97_RS14630 MATE family efflux transporter 0.17 ABID97_RS00440 ROK family protein low > 91
Bosea sp. OAE506 0.18 ABIE41_RS08515 MATE family efflux transporter 0.18 ABIE41_RS06840 ROK family protein low > 77
Bacteroides ovatus ATCC 8483 0.17 BACOVA_03650 MATE efflux family protein 0.18 BACOVA_01791 hypothetical protein low > 96
Phaeobacter inhibens DSM 17395 0.17 PGA1_c21310 multidrug resistance protein NorM 0.19 PGA1_262p00420 Transcriptional regulator/sugar kinase low > 62
Azospirillum brasilense Sp245 0.14 AZOBR_RS15325 multidrug transporter 0.17 AZOBR_RS27950 transcriptional regulator low > 97
Caulobacter crescentus NA1000 Δfur 0.13 CCNA_02099 Na+ driven multidrug efflux pump 0.09 CCNA_01870 NagC-family transcriptional regulator low > 67
Caulobacter crescentus NA1000 0.13 CCNA_02099 Na+ driven multidrug efflux pump 0.09 CCNA_01870 NagC-family transcriptional regulator low > 66

Not shown: 69 genomes with orthologs for CSW01_07735 only; 2 genomes with orthologs for CSW01_10020 only