| Organism | Ratio1 | Gene1 | Name1 | Description1 | Ratio2 | Gene2 | Name2 | Description2 | Cofit | Rank |
| Vibrio cholerae E7946 ATCC 55056 | 1.0 | CSW01_13640 | | DNA-binding response regulator | 1.0 | CSW01_07595 | | formate dehydrogenase | 0.48 | 5 |
| Shewanella amazonensis SB2B | 0.54 | Sama_2076 | | response regulator receiver protein (RefSeq) | 0.72 | Sama_3609 | | formate dehydrogenase, alpha subunit (RefSeq) | low | > 62 |
| Marinobacter adhaerens HP15 | 0.53 | HP15_812 | | two component transcriptional regulator, LuxR family | 0.67 | HP15_4120 | | secreted protein containing molybdopterin oxidoreductase / molybdopterin dinucleotide-binding region | — | — |
| Shewanella sp. ANA-3 | 0.52 | Shewana3_1732 | | two component LuxR family transcriptional regulator (RefSeq) | 0.72 | Shewana3_3920 | | formate dehydrogenase alpha subunit (RefSeq) | low | > 73 |
| Shewanella oneidensis MR-1 | 0.52 | SO2648 | | DNA-binding response regulator, LuxR family (NCBI ptt file) | 0.71 | SO4513 | | formate dehydrogenase, alpha subunit (NCBI ptt file) | low | > 76 |
| Shewanella loihica PV-4 | 0.52 | Shew_1545 | | two component LuxR family transcriptional regulator (RefSeq) | 0.73 | Shew_0059 | | molybdopterin oxidoreductase (RefSeq) | — | — |
| Pseudomonas sp. SVBP6 | 0.51 | COO64_RS19960 | erdR | response regulator transcription factor ErdR | 0.12 | COO64_RS16015 | fdnG | formate dehydrogenase-N subunit alpha | low | > 93 |
| Pseudomonas fluorescens FW300-N1B4 | 0.50 | Pf1N1B4_3150 | | Transcriptional regulator, LuxR family | 0.12 | Pf1N1B4_4947 | | Formate dehydrogenase O alpha subunit (EC 1.2.1.2) @ selenocysteine-containing | — | — |
| Azospirillum sp. SherDot2 | 0.47 | MPMX19_06084 | | Transcriptional regulatory protein LnrK | 0.65 | MPMX19_00548 | | Periplasmic nitrate reductase | low | > 112 |
| Bosea sp. OAE506 | 0.47 | ABIE41_RS24085 | | response regulator transcription factor | 0.53 | ABIE41_RS23365 | | formate dehydrogenase subunit alpha | — | — |
| Acidovorax sp. GW101-3H11 | 0.43 | Ac3H11_716 | | Transcriptional regulator, LuxR family | 0.61 | Ac3H11_3803 | | Formate dehydrogenase-O, major subunit (EC 1.2.1.2) | — | — |
| Sinorhizobium meliloti 1021 | 0.42 | SMc02248 | | transcriptional regulator | 0.12 | SMa0002 | | formate dehydrogenase subunit alpha | low | > 103 |
| Azospirillum brasilense Sp245 | 0.41 | AZOBR_RS12735 | | transcriptional regulator | 0.65 | AZOBR_RS05250 | | formate dehydrogenase | low | > 97 |
| Dinoroseobacter shibae DFL-12 | 0.36 | Dshi_0465 | | two component transcriptional regulator, LuxR family (RefSeq) | 0.56 | Dshi_0504 | | molybdopterin oxidoreductase (RefSeq) | 0.31 | 7 |
| Phaeobacter inhibens DSM 17395 | 0.35 | PGA1_c22610 | | putative transcriptional regulator, containing response regulator domain | 0.67 | PGA1_c27650 | | putative formate dehydrogenase H | 0.29 | 5 |
| Magnetospirillum magneticum AMB-1 | 0.35 | AMB_RS13915 | | DNA-binding response regulator | 0.65 | AMB_RS13440 | | formate dehydrogenase | low | > 64 |
| Variovorax sp. OAS795 | 0.29 | ABID97_RS05205 | | response regulator transcription factor | 0.59 | ABID97_RS07565 | | formate dehydrogenase subunit alpha | low | > 91 |
| Hydrogenophaga sp. GW460-11-11-14-LB1 | 0.25 | GFF107 | | Transcriptional regulator, LuxR family | 0.61 | GFF1193 | | Formate dehydrogenase-O, major subunit (EC 1.2.1.2) | low | > 90 |
| Ralstonia sp. UNC404CL21Col | 0.25 | ABZR87_RS00385 | | response regulator transcription factor | 0.61 | ABZR87_RS16220 | | molybdopterin-dependent oxidoreductase | low | > 80 |
| Ralstonia solanacearum PSI07 | 0.24 | RPSI07_RS12620 | | DNA-binding response regulator | 0.60 | RPSI07_RS13005 | | formate dehydrogenase | low | > 81 |
| Ralstonia solanacearum IBSBF1503 | 0.24 | RALBFv3_RS04765 | | DNA-binding response regulator | 0.60 | RALBFv3_RS04365 | | formate dehydrogenase | — | — |
| Ralstonia solanacearum UW163 | 0.24 | UW163_RS08905 | | DNA-binding response regulator | 0.60 | UW163_RS09305 | | formate dehydrogenase | — | — |
| Cupriavidus basilensis FW507-4G11 | 0.24 | RR42_RS27790 | | LuxR family transcriptional regulator | 0.59 | RR42_RS15980 | | formate dehydrogenase | low | > 128 |
Not shown: 45 genomes with orthologs for CSW01_13640 only; 1 genomes with orthologs for CSW01_07595 only