Conservation of cofitness between CSW01_02270 and CSW01_04620 in Vibrio cholerae E7946 ATCC 55056

43 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Vibrio cholerae E7946 ATCC 55056 1.0 CSW01_02270 malate dehydrogenase 1.0 CSW01_04620 NADPH-dependent 7-cyano-7-deazaguanine reductase QueF 0.51 16
Escherichia coli ECOR27 0.82 NOLOHH_09595 mdh malate dehydrogenase 0.62 NOLOHH_12070 queF NADPH-dependent 7-cyano-7-deazaguanine reductase QueF low > 76
Escherichia coli ECRC99 0.82 KEDOAH_10355 mdh malate dehydrogenase 0.63 KEDOAH_07940 queF NADPH-dependent 7-cyano-7-deazaguanine reductase QueF — —
Escherichia coli ECRC102 0.82 NIAGMN_15555 mdh malate dehydrogenase 0.63 NIAGMN_17960 queF NADPH-dependent 7-cyano-7-deazaguanine reductase QueF low > 80
Escherichia coli BW25113 0.82 b3236 mdh malate dehydrogenase (NCBI) 0.62 b2794 yqcD hypothetical protein (NCBI) low > 76
Escherichia fergusonii Becca 0.82 EFB2_00594 Malate dehydrogenase 0.62 EFB2_01123 NADPH-dependent 7-cyano-7-deazaguanine reductase low > 86
Escherichia coli ECRC98 0.82 JDDGAC_21420 mdh malate dehydrogenase 0.63 JDDGAC_23855 queF NADPH-dependent 7-cyano-7-deazaguanine reductase QueF low > 87
Escherichia coli HS(pFamp)R (ATCC 700891) 0.82 OHPLBJKB_00468 Malate dehydrogenase 0.62 OHPLBJKB_00937 NADPH-dependent 7-cyano-7-deazaguanine reductase low > 74
Escherichia coli ECRC62 0.82 BNILDI_01940 mdh malate dehydrogenase 0.62 BNILDI_10575 queF NADPH-dependent 7-cyano-7-deazaguanine reductase QueF low > 75
Escherichia coli ECRC100 0.82 OKFHMN_17795 mdh malate dehydrogenase 0.63 OKFHMN_20190 queF NADPH-dependent 7-cyano-7-deazaguanine reductase QueF low > 79
Escherichia coli BL21 0.82 ECD_03096 malate dehydrogenase, NAD(P)-binding 0.62 ECD_02639 7-cyano-7-deazaguanine reductase (NADPH-dependent) low > 61
Escherichia coli Nissle 1917 0.82 ECOLIN_RS18555 malate dehydrogenase 0.62 ECOLIN_RS15580 NADPH-dependent 7-cyano-7-deazaguanine reductase QueF low > 55
Escherichia coli ECRC101 0.82 MCAODC_08315 mdh malate dehydrogenase 0.63 MCAODC_10715 queF NADPH-dependent 7-cyano-7-deazaguanine reductase QueF low > 87
Escherichia coli ECOR38 0.82 HEPCGN_16660 mdh malate dehydrogenase 0.63 HEPCGN_19445 queF NADPH-dependent 7-cyano-7-deazaguanine reductase QueF low > 88
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.81 GFF2149 Malate dehydrogenase (EC 1.1.1.37) 0.62 GFF4849 NADPH dependent preQ0 reductase (EC 1.7.1.13) low > 78
Shewanella sp. ANA-3 0.81 Shewana3_3509 malate dehydrogenase (RefSeq) 0.59 Shewana3_2835 queF 7-cyano-7-deazaguanine reductase (RefSeq) low > 73
Enterobacter sp. TBS_079 0.81 MPMX20_04140 Malate dehydrogenase 0.60 MPMX20_03664 NADPH-dependent 7-cyano-7-deazaguanine reductase low > 85
Enterobacter asburiae PDN3 0.81 EX28DRAFT_3285 malate dehydrogenase (NAD) (EC 1.1.1.37) 0.61 EX28DRAFT_2876 7-cyano-7-deazaguanine reductase low > 76
Klebsiella pneumoniae MKP103 0.81 KDGMDA_06200 malate dehydrogenase 0.66 KDGMDA_03395 NADPH-dependent 7-cyano-7-deazaguanine reductase QueF low > 95
Klebsiella michiganensis M5al 0.81 BWI76_RS25420 malate dehydrogenase 0.64 BWI76_RS22865 NADPH-dependent 7-cyano-7-deazaguanine reductase low > 92
Shewanella oneidensis MR-1 0.81 SO0770 mdh malate dehydrogenase (NCBI ptt file) 0.59 SO1608 conserved hypothetical protein (NCBI ptt file) low > 76
Pectobacterium carotovorum WPP14 0.80 HER17_RS18390 malate dehydrogenase 0.59 HER17_RS16390 NADPH-dependent 7-cyano-7-deazaguanine reductase QueF low > 75
Pantoea agglomerans CFBP13505 P0401 0.80 PagCFBP13505_RS11115 malate dehydrogenase 0.60 PagCFBP13505_RS16920 NADPH-dependent 7-cyano-7-deazaguanine reductase QueF low > 74
Shewanella amazonensis SB2B 0.80 Sama_0672 malate dehydrogenase (RefSeq) 0.56 Sama_1120 queF 7-cyano-7-deazaguanine reductase (RefSeq) low > 62
Pantoea sp. MT58 0.80 IAI47_02520 malate dehydrogenase 0.60 IAI47_04050 NADPH-dependent 7-cyano-7-deazaguanine reductase QueF low > 76
Erwinia tracheiphila HP pepo 2.2 0.79 IJEDHG_13655 mdh malate dehydrogenase 0.60 IJEDHG_17300 queF NADPH-dependent 7-cyano-7-deazaguanine reductase QueF low > 61
Erwinia tracheiphila SCR3 0.79 LU632_RS21365 mdh malate dehydrogenase 0.60 LU632_RS06280 queF NADPH-dependent 7-cyano-7-deazaguanine reductase QueF low > 73
Shewanella loihica PV-4 0.79 Shew_0867 malate dehydrogenase (RefSeq) 0.58 Shew_2654 queF 7-cyano-7-deazaguanine reductase (RefSeq) low > 60
Rahnella sp. WP5 0.79 EX31_RS08645 malate dehydrogenase 0.61 EX31_RS13085 NADPH-dependent 7-cyano-7-deazaguanine reductase QueF low > 89
Serratia liquefaciens MT49 0.79 IAI46_01825 malate dehydrogenase 0.51 IAI46_21580 NADPH-dependent 7-cyano-7-deazaguanine reductase QueF low > 87
Dickeya dianthicola ME23 0.79 DZA65_RS03130 malate dehydrogenase 0.50 DZA65_RS04535 NADPH-dependent 7-cyano-7-deazaguanine reductase QueF low > 75
Dickeya dadantii 3937 0.79 DDA3937_RS02970 malate dehydrogenase 0.51 DDA3937_RS04655 NADPH-dependent 7-cyano-7-deazaguanine reductase QueF 0.45 10
Dickeya dianthicola 67-19 0.79 HGI48_RS03135 malate dehydrogenase 0.51 HGI48_RS04615 NADPH-dependent 7-cyano-7-deazaguanine reductase QueF low > 71
Erwinia amylovora T8 0.77 OLJFJH_06980 malate dehydrogenase 0.62 OLJFJH_09195 NADPH-dependent 7-cyano-7-deazaguanine reductase QueF low > 58
Alteromonas macleodii MIT1002 0.69 MIT1002_03492 Malate dehydrogenase 0.55 MIT1002_00988 NADPH-dependent 7-cyano-7-deazaguanine reductase — —
Pseudomonas sp. BP01 0.12 JOY50_RS27245 malate dehydrogenase 0.49 JOY50_RS25160 queF NADPH-dependent 7-cyano-7-deazaguanine reductase QueF low > 84
Acidovorax sp. GW101-3H11 0.11 Ac3H11_3153 Malate dehydrogenase (EC 1.1.1.37) 0.49 Ac3H11_1595 NADPH dependent preQ0 reductase (EC 1.7.1.13) — —
Rhodanobacter sp000427505 FW510-R12 0.10 LRK53_RS09435 malate dehydrogenase 0.52 LRK53_RS03330 NADPH-dependent 7-cyano-7-deazaguanine reductase QueF low > 59
Variovorax sp. SCN45 0.10 GFF3901 Malate dehydrogenase (EC 1.1.1.37) 0.45 GFF6017 NADPH-dependent 7-cyano-7-deazaguanine reductase (EC 1.7.1.13) — —
Rhodanobacter denitrificans MT42 0.10 LRK55_RS00495 malate dehydrogenase 0.49 LRK55_RS10150 NADPH-dependent 7-cyano-7-deazaguanine reductase QueF — —
Rhodanobacter denitrificans FW104-10B01 0.10 LRK54_RS00720 malate dehydrogenase 0.49 LRK54_RS10510 NADPH-dependent 7-cyano-7-deazaguanine reductase QueF — —
Variovorax sp. OAS795 0.10 ABID97_RS08515 malate dehydrogenase 0.45 ABID97_RS07920 NADPH-dependent 7-cyano-7-deazaguanine reductase QueF — —
Hydrogenophaga sp. GW460-11-11-14-LB1 0.09 GFF3372 Malate dehydrogenase (EC 1.1.1.37) 0.49 GFF722 NADPH dependent preQ0 reductase (EC 1.7.1.13) — —
Rhodanobacter sp. FW510-T8 0.09 OKGIIK_06530 mdh malate dehydrogenase 0.52 OKGIIK_13395 queF NADPH-dependent 7-cyano-7-deazaguanine reductase QueF — —

Not shown: 30 genomes with orthologs for CSW01_02270 only; 42 genomes with orthologs for CSW01_04620 only