Conservation of cofitness between CSW01_01845 and CSW01_00850 in Vibrio cholerae E7946 ATCC 55056

77 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Vibrio cholerae E7946 ATCC 55056 1.0 CSW01_01845 protease modulator HflK 1.0 CSW01_00850 multidrug resistance protein 0.51 19
Shewanella sp. ANA-3 0.51 Shewana3_0599 HflK protein (RefSeq) 0.72 Shewana3_0371 acriflavin resistance protein (RefSeq) low > 73
Escherichia fergusonii Becca 0.49 EFB2_04361 Modulator of FtsH protease HflK 0.24 EFB2_01418 Multidrug efflux pump subunit AcrB low > 86
Escherichia coli ECOR38 0.49 HEPCGN_10475 hflK FtsH protease activity modulator HflK 0.24 HEPCGN_21140 acrD multidrug efflux RND transporter permease AcrD low > 88
Escherichia coli Nissle 1917 0.49 ECOLIN_RS24240 FtsH protease activity modulator HflK 0.24 ECOLIN_RS14090 multidrug efflux RND transporter permease AcrD low > 55
Escherichia coli ECRC62 0.48 BNILDI_06980 hflK FtsH protease activity modulator HflK 0.24 BNILDI_12460 acrD multidrug efflux RND transporter permease AcrD low > 75
Escherichia coli BW25113 0.48 b4174 hflK modulator for HflB protease specific for phage lambda cII repressor (NCBI) 0.24 b2470 acrD aminoglycoside/multidrug efflux system (NCBI) low > 76
Escherichia coli ECOR27 0.48 NOLOHH_04510 hflK FtsH protease activity modulator HflK 0.24 NOLOHH_13650 acrD multidrug efflux RND transporter permease AcrD low > 76
Escherichia coli ECRC102 0.48 NIAGMN_10095 hflK FtsH protease activity modulator HflK 0.24 NIAGMN_19740 acrD multidrug efflux RND transporter permease AcrD — —
Escherichia coli ECRC100 0.48 OKFHMN_12245 hflK FtsH protease activity modulator HflK 0.24 OKFHMN_21970 acrD multidrug efflux RND transporter permease AcrD low > 79
Escherichia coli BL21 0.48 ECD_04041 modulator for HflB protease specific for phage lambda cII repressor 0.24 ECD_02361 aminoglycoside/multidrug efflux system low > 61
Escherichia coli HS(pFamp)R (ATCC 700891) 0.48 OHPLBJKB_03868 Modulator of FtsH protease HflK 0.24 OHPLBJKB_01261 Multidrug efflux pump subunit AcrB low > 74
Escherichia coli ECRC101 0.48 MCAODC_02760 hflK FtsH protease activity modulator HflK 0.24 MCAODC_12500 acrD multidrug efflux RND transporter permease AcrD low > 88
Escherichia coli ECRC98 0.48 JDDGAC_15885 hflK FtsH protease activity modulator HflK 0.24 JDDGAC_25915 acrD multidrug efflux RND transporter permease AcrD low > 87
Klebsiella pneumoniae MKP103 0.48 KDGMDA_11045 FtsH protease activity modulator HflK 0.24 KDGMDA_14835 acriflavine resistance protein B 0.66 23
Escherichia coli ECRC99 0.48 KEDOAH_15910 hflK FtsH protease activity modulator HflK 0.24 KEDOAH_06250 acrD multidrug efflux RND transporter permease AcrD — —
Enterobacter asburiae PDN3 0.48 EX28DRAFT_3371 HflK protein 0.24 EX28DRAFT_2496 The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family low > 76
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.48 GFF827 HflK protein 0.24 GFF4246 RND efflux system, inner membrane transporter CmeB low > 78
Dickeya dadantii 3937 0.48 DDA3937_RS18600 FtsH protease activity modulator HflK 0.23 DDA3937_RS05735 multidrug efflux RND transporter permease subunit low > 74
Dickeya dianthicola ME23 0.48 DZA65_RS19670 FtsH protease activity modulator HflK 0.22 DZA65_RS06115 multidrug efflux RND transporter permease subunit low > 75
Dickeya dianthicola 67-19 0.48 HGI48_RS18535 FtsH protease activity modulator HflK 0.22 HGI48_RS05790 multidrug efflux RND transporter permease subunit low > 71
Shewanella amazonensis SB2B 0.47 Sama_3023 hflK protein (RefSeq) 0.71 Sama_3269 putative multidrug resistance protein (RefSeq) low > 62
Pantoea sp. MT58 0.47 IAI47_02600 FtsH protease activity modulator HflK 0.23 IAI47_05310 multidrug efflux RND transporter permease AcrD low > 76
Pectobacterium carotovorum WPP14 0.46 HER17_RS02595 FtsH protease activity modulator HflK 0.23 HER17_RS01560 multidrug efflux RND transporter permease AcrD low > 75
Erwinia tracheiphila HP pepo 2.2 0.46 IJEDHG_06855 hflK FtsH protease activity modulator HflK 0.21 IJEDHG_16580 adeB hydrophobe/amphiphile efflux-1 family RND transporter — —
Erwinia tracheiphila SCR3 0.46 LU632_RS02065 hflK FtsH protease activity modulator HflK 0.22 LU632_RS18185 efflux RND transporter permease subunit — —
Pantoea agglomerans CFBP13505 P0401 0.46 PagCFBP13505_RS11195 FtsH protease activity modulator HflK 0.23 PagCFBP13505_RS19855 multidrug efflux RND transporter permease AcrD low > 74
Enterobacter sp. TBS_079 0.46 MPMX20_00455 Modulator of FtsH protease HflK 0.24 MPMX20_01064 Multidrug efflux pump subunit AcrB 0.50 43
Klebsiella michiganensis M5al 0.45 BWI76_RS02545 protease modulator HflK 0.24 BWI76_RS06775 multidrug efflux RND transporter permease subunit low > 92
Serratia liquefaciens MT49 0.45 IAI46_01635 FtsH protease activity modulator HflK 0.23 IAI46_18690 multidrug efflux RND transporter permease AcrD low > 86
Rahnella sp. WP5 0.45 EX31_RS08810 FtsH protease activity modulator HflK 0.23 EX31_RS22470 multidrug efflux RND transporter permease subunit low > 89
Erwinia amylovora T8 0.44 OLJFJH_02490 FtsH protease activity modulator HflK 0.22 OLJFJH_17855 multidrug efflux RND transporter permease subunit AcrB low > 58
Marinobacter adhaerens HP15 0.37 HP15_2497 HflK 0.46 HP15_3262 multidrug resistance protein low > 73
Pseudomonas fluorescens FW300-N1B4 0.37 Pf1N1B4_1410 HflK protein 0.47 Pf1N1B4_720 RND multidrug efflux transporter; Acriflavin resistance protein — —
Pseudomonas fluorescens FW300-N2C3 0.36 AO356_08645 hypothetical protein 0.47 AO356_18440 acriflavine resistance protein B low > 104
Pseudomonas fluorescens SBW25-INTG 0.36 PFLU_RS02580 FtsH protease activity modulator HflK 0.47 PFLU_RS24405 multidrug efflux RND transporter permease subunit low > 109
Pseudomonas fluorescens SBW25 0.36 PFLU_RS02580 FtsH protease activity modulator HflK 0.47 PFLU_RS24405 multidrug efflux RND transporter permease subunit low > 109
Pseudomonas aeruginosa PA14 0.36 IKLFDK_28830 FtsH protease activity modulator HflK 0.46 IKLFDK_02225 multidrug efflux RND transporter permease subunit MexW — —
Pseudomonas fluorescens FW300-N2E3 0.36 AO353_13155 hypothetical protein 0.46 AO353_04000 acriflavine resistance protein B low > 101
Pseudomonas segetis P6 0.36 MPMX49_04151 Modulator of FtsH protease HflK 0.48 MPMX49_03771 Multidrug efflux pump subunit AcrB low > 75
Pseudomonas sp. RS175 0.36 PFR28_05123 Modulator of FtsH protease HflK 0.47 PFR28_03330 Multidrug efflux pump subunit AcrB low > 88
Pseudomonas syringae pv. syringae B728a 0.35 Psyr_0574 protease FtsH subunit HflK 0.23 Psyr_2968 Hydrophobe/amphiphile efflux-1 HAE1 low > 86
Pseudomonas syringae pv. syringae B728a ΔmexB 0.35 Psyr_0574 protease FtsH subunit HflK 0.23 Psyr_2968 Hydrophobe/amphiphile efflux-1 HAE1 low > 86
Pseudomonas sp. DMC3 0.35 GFF3222 Modulator of FtsH protease HflK 0.46 GFF5069 Multidrug efflux pump subunit AcrB low > 89
Dechlorosoma suillum PS 0.35 Dsui_3135 HflK protein 0.35 Dsui_1555 cation/multidrug efflux pump — —
Pseudomonas fluorescens FW300-N2E2 0.35 Pf6N2E2_3612 HflK protein 0.47 Pf6N2E2_5614 RND multidrug efflux transporter; Acriflavin resistance protein low > 103
Pseudomonas simiae WCS417 0.35 PS417_02500 membrane protein 0.47 PS417_22755 acriflavine resistance protein B — —
Pseudomonas lactucae CFBP13502 0.35 GEMAOFIL_00738 Modulator of FtsH protease HflK 0.23 GEMAOFIL_03223 multidrug efflux RND transporter permease subunit OqxB9 low > 93
Pseudomonas fluorescens GW456-L13 0.35 PfGW456L13_152 HflK protein 0.45 PfGW456L13_1771 RND multidrug efflux transporter; Acriflavin resistance protein low > 87
Ralstonia solanacearum PSI07 0.34 RPSI07_RS18065 FtsH protease activity modulator HflK 0.22 RPSI07_RS23905 hydrophobe/amphiphile efflux-1 family RND transporter low > 81
Pseudomonas sp. SVBP6 0.34 COO64_RS17910 hflK FtsH protease activity modulator HflK 0.46 COO64_RS12055 multidrug efflux RND transporter permease subunit low > 93
Pseudomonas sp. S08-1 0.34 OH686_09460 HflK protein 0.47 OH686_17360 Multidrug efflux system, inner membrane proton/drug antiporter (RND type) low > 80
Pseudomonas putida KT2440 0.34 PP_4892 integral membrane ATP-dependent zinc metallopeptidase / HflK-HflC complex 0.46 PP_0906 putative Multidrug efflux RND transporter low > 96
Pseudomonas stutzeri RCH2 0.34 Psest_0685 HflK protein 0.45 Psest_1153 Cation/multidrug efflux pump — —
Pseudomonas sp. BP01 0.34 JOY50_RS17240 hflK FtsH protease activity modulator HflK 0.47 JOY50_RS14955 multidrug efflux RND transporter permease subunit low > 84
Ralstonia solanacearum IBSBF1503 0.33 RALBFv3_RS15310 FtsH protease activity modulator HflK 0.22 RALBFv3_RS09445 multidrug efflux RND transporter permease subunit low > 76
Castellaniella sp019104865 MT123 0.33 ABCV34_RS02660 FtsH protease activity modulator HflK 0.20 ABCV34_RS14620 multidrug efflux RND transporter permease subunit — —
Ralstonia solanacearum UW163 0.33 UW163_RS12775 FtsH protease activity modulator HflK 0.22 UW163_RS04135 multidrug efflux RND transporter permease subunit — —
Hydrogenophaga sp. GW460-11-11-14-LB1 0.33 GFF4856 HflK protein 0.34 GFF4261 RND multidrug efflux transporter; Acriflavin resistance protein low > 90
Variovorax sp. SCN45 0.33 GFF1002 HflK protein 0.45 GFF3509 Multidrug efflux system, inner membrane proton/drug antiporter (RND type) => MexI of MexHI-OpmD system low > 127
Methylophilus sp. DMC18 0.32 GFF1223 hypothetical protein 0.24 GFF1649 Efflux pump membrane transporter BepE low > 43
Cupriavidus basilensis FW507-4G11 0.32 RR42_RS13105 membrane protein 0.22 RR42_RS32420 multidrug efflux RND transporter permease subunit — —
Ralstonia sp. UNC404CL21Col 0.32 ABZR87_RS10950 FtsH protease activity modulator HflK 0.22 ABZR87_RS09795 efflux RND transporter permease subunit low > 80
Herbaspirillum seropedicae SmR1 0.31 HSERO_RS14765 membrane protein 0.23 HSERO_RS23055 multidrug transporter low > 78
Ralstonia solanacearum GMI1000 0.31 RS_RS06120 FtsH protease activity modulator HflK 0.22 RS_RS00045 multidrug efflux RND transporter permease subunit low > 80
Kangiella aquimarina DSM 16071 0.31 B158DRAFT_1954 protease FtsH subunit HflK 0.23 B158DRAFT_0733 The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family low > 40
Acidovorax sp. GW101-3H11 0.31 Ac3H11_1801 HflK protein 0.34 Ac3H11_482 RND multidrug efflux transporter; Acriflavin resistance protein low > 79
Rhodanobacter sp. FW510-T8 0.29 OKGIIK_06640 hflK FtsH protease activity modulator HflK 0.23 OKGIIK_11990 acrB acriflavine resistance protein B low > 52
Rhodanobacter sp000427505 FW510-R12 0.28 LRK53_RS09535 FtsH protease activity modulator HflK 0.22 LRK53_RS07935 multidrug efflux RND transporter permease subunit low > 59
Rhodanobacter denitrificans FW104-10B01 0.28 LRK54_RS00620 FtsH protease activity modulator HflK 0.23 LRK54_RS11905 efflux RND transporter permease subunit low > 59
Rhodanobacter denitrificans MT42 0.28 LRK55_RS00390 FtsH protease activity modulator HflK 0.23 LRK55_RS11630 efflux RND transporter permease subunit low > 63
Dyella japonica UNC79MFTsu3.2 0.27 ABZR86_RS08355 FtsH protease activity modulator HflK 0.23 ABZR86_RS11745 efflux RND transporter permease subunit low > 74
Xanthobacter sp. DMC5 0.27 GFF3169 Modulator of FtsH protease HflK 0.40 GFF2738 Efflux pump membrane transporter BepE — —
Rhodospirillum rubrum S1H 0.26 Rru_A2203 HflK (NCBI) 0.49 Rru_A3699 Acriflavin resistance protein (NCBI) — —
Rhodopseudomonas palustris CGA009 0.26 TX73_018080 FtsH protease activity modulator HflK 0.48 TX73_019545 MexW/MexI family multidrug efflux RND transporter permease subunit low > 86
Magnetospirillum magneticum AMB-1 0.25 AMB_RS17650 FtsH protease activity modulator HflK 0.48 AMB_RS17260 acriflavine resistance protein B — —
Bosea sp. OAE506 0.25 ABIE41_RS12850 FtsH protease activity modulator HflK 0.23 ABIE41_RS01595 efflux RND transporter permease subunit low > 77
Azospirillum sp. SherDot2 0.23 MPMX19_01251 Modulator of FtsH protease HflK 0.48 MPMX19_05610 Efflux pump membrane transporter BepE — —

Not shown: 9 genomes with orthologs for CSW01_01845 only; 14 genomes with orthologs for CSW01_00850 only