Conservation of cofitness between BWI76_RS10700 and BWI76_RS26425 in Klebsiella michiganensis M5al

37 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Klebsiella michiganensis M5al 1.0 BWI76_RS10700 XRE family transcriptional regulator 1.0 BWI76_RS26425 zinc/cadmium/mercury/lead-transporting ATPase 0.25 7
Enterobacter asburiae PDN3 0.98 EX28DRAFT_1500 Predicted transcriptional regulators 0.74 EX28DRAFT_4303 heavy metal-(Cd/Co/Hg/Pb/Zn)-translocating P-type ATPase low > 76
Escherichia coli HS(pFamp)R (ATCC 700891) 0.97 OHPLBJKB_02383 HTH-type transcriptional regulator PuuR 0.73 OHPLBJKB_00234 Zinc/cadmium/lead-transporting P-type ATPase low > 73
Escherichia coli BW25113 0.97 b1299 puuR DNA-binding transcriptional repressor (NCBI) 0.73 b3469 zntA zinc, cobalt and lead efflux system (NCBI) low > 76
Escherichia coli ECOR27 0.97 NOLOHH_20120 puuR HTH-type transcriptional regulator PuuR 0.74 NOLOHH_08480 zntA Zn(II)/Cd(II)/Pb(II) translocating P-type ATPase ZntA low > 75
Escherichia coli ECRC62 0.97 BNILDI_18270 puuR HTH-type transcriptional regulator PuuR 0.74 BNILDI_03035 zntA Zn(II)/Cd(II)/Pb(II) translocating P-type ATPase ZntA low > 75
Escherichia coli ECOR38 0.97 HEPCGN_25765 puuR HTH-type transcriptional regulator PuuR 0.74 HEPCGN_15505 zntA Zn(II)/Cd(II)/Pb(II) translocating P-type ATPase ZntA low > 87
Escherichia coli BL21 0.97 ECD_01276 repressor for the divergent puu operons, putrescine inducible 0.73 ECD_03318 zinc, cobalt and lead efflux system low > 61
Escherichia coli ECRC100 0.97 OKFHMN_02435 puuR HTH-type transcriptional regulator PuuR 0.73 OKFHMN_16675 zntA Zn(II)/Cd(II)/Pb(II) translocating P-type ATPase ZntA low > 80
Escherichia coli ECRC101 0.97 MCAODC_15835 puuR HTH-type transcriptional regulator PuuR 0.73 MCAODC_07205 zntA Zn(II)/Cd(II)/Pb(II) translocating P-type ATPase ZntA low > 87
Escherichia coli ECRC98 0.97 JDDGAC_04980 puuR HTH-type transcriptional regulator PuuR 0.73 JDDGAC_20305 zntA Zn(II)/Cd(II)/Pb(II) translocating P-type ATPase ZntA low > 86
Escherichia coli ECRC102 0.97 NIAGMN_26605 puuR HTH-type transcriptional regulator PuuR 0.73 NIAGMN_14445 zntA Zn(II)/Cd(II)/Pb(II) translocating P-type ATPase ZntA
Escherichia coli ECRC99 0.97 KEDOAH_26340 puuR HTH-type transcriptional regulator PuuR 0.73 KEDOAH_11465 zntA Zn(II)/Cd(II)/Pb(II) translocating P-type ATPase ZntA
Serratia liquefaciens MT49 0.89 IAI46_10550 HTH-type transcriptional regulator PuuR 0.61 IAI46_00855 zinc/cadmium/mercury/lead-transporting ATPase low > 86
Rahnella sp. WP5 0.80 EX31_RS17905 HTH-type transcriptional regulator PuuR 0.60 EX31_RS14850 zinc/cadmium/mercury/lead-transporting ATPase low > 89
Pantoea sp. MT58 0.74 IAI47_07115 HTH-type transcriptional regulator PuuR 0.56 IAI47_01515 zinc/cadmium/mercury/lead-transporting ATPase low > 76
Pseudomonas sp. RS175 0.38 PFR28_04396 HTH-type transcriptional regulator PuuR 0.27 PFR28_04824 Cadmium-transporting ATPase 0.25 72
Pseudomonas fluorescens FW300-N2E3 0.38 AO353_09140 XRE family transcriptional regulator 0.28 AO353_08420 ATPase P low > 101
Pseudomonas putida KT2440 0.37 PP_5268 DNA-binding transcriptional repressor PuuR-putrescine 0.30 PP_5139 cadmium translocating P-type ATPase low > 96
Pseudomonas fluorescens GW456-L13 0.37 PfGW456L13_815 Putrescine utilization regulator 0.28 PfGW456L13_959 Lead, cadmium, zinc and mercury transporting ATPase (EC 3.6.3.3) (EC 3.6.3.5); Copper-translocating P-type ATPase (EC 3.6.3.4) low > 87
Pseudomonas fluorescens FW300-N2C3 0.37 AO356_12635 XRE family transcriptional regulator 0.28 AO356_10380 ATPase P low > 104
Pseudomonas fluorescens FW300-N2E2 0.37 Pf6N2E2_4394 Putrescine utilization regulator 0.28 Pf6N2E2_3948 Lead, cadmium, zinc and mercury transporting ATPase (EC 3.6.3.3) (EC 3.6.3.5); Copper-translocating P-type ATPase (EC 3.6.3.4) low > 103
Pseudomonas syringae pv. syringae B728a 0.37 Psyr_0238 Helix-turn-helix motif protein 0.28 Psyr_4837 Heavy metal-(Cd/Co/Hg/Pb/Zn)-translocating P-type ATPase:Heavy metal translocating P-type ATPase low > 86
Pseudomonas syringae pv. syringae B728a ΔmexB 0.37 Psyr_0238 Helix-turn-helix motif protein 0.28 Psyr_4837 Heavy metal-(Cd/Co/Hg/Pb/Zn)-translocating P-type ATPase:Heavy metal translocating P-type ATPase low > 86
Pseudomonas simiae WCS417 0.36 PS417_27690 XRE family transcriptional regulator 0.29 PS417_26955 ATPase P
Pseudomonas fluorescens FW300-N1B4 0.36 Pf1N1B4_2147 Putrescine utilization regulator 0.28 Pf1N1B4_2291 Lead, cadmium, zinc and mercury transporting ATPase (EC 3.6.3.3) (EC 3.6.3.5); Copper-translocating P-type ATPase (EC 3.6.3.4) low > 87
Pseudomonas fluorescens SBW25 0.36 PFLU_RS29365 cupin domain-containing protein 0.29 PFLU_RS28615 heavy metal translocating P-type ATPase low > 109
Pseudomonas fluorescens SBW25-INTG 0.36 PFLU_RS29365 cupin domain-containing protein 0.29 PFLU_RS28615 heavy metal translocating P-type ATPase low > 109
Azospirillum sp. SherDot2 0.32 MPMX19_04921 HTH-type transcriptional regulator PuuR 0.37 MPMX19_06375 Zinc/cadmium/lead-transporting P-type ATPase low > 112
Bosea sp. OAE506 0.32 ABIE41_RS05345 cupin domain-containing protein 0.35 ABIE41_RS14225 heavy metal translocating P-type ATPase
Azospirillum brasilense Sp245 0.31 AZOBR_RS19640 aldehyde dehydrogenase 0.38 AZOBR_RS26655 ATPase low > 97
Rhodospirillum rubrum S1H 0.30 Rru_A2042 Transcriptional Regulator, XRE family with Cupin sensor domain (NCBI) 0.32 Rru_A1027 (Cd/Co/Hg/Pb/Zn)-translocating P-type ATPase (NCBI) low > 58
Sinorhizobium meliloti 1021 0.29 SMc04387 aldehyde dehydrogenase 0.39 SMc04128 heavy metal transporting ATPase low > 103
Cupriavidus basilensis FW507-4G11 0.21 RR42_RS00225 XRE family transcriptional regulator 0.26 RR42_RS30930 4-deoxy-4-formamido-L-arabinose-phospho-UDP deformylase low > 128
Vibrio cholerae E7946 ATCC 55056 0.16 CSW01_15345 XRE family transcriptional regulator 0.51 CSW01_05250 zinc/cadmium/mercury/lead-transporting ATPase low > 62
Ralstonia solanacearum UW163 0.15 UW163_RS12430 XRE family transcriptional regulator 0.23 UW163_RS17330 heavy metal translocating P-type ATPase
Ralstonia solanacearum IBSBF1503 0.15 RALBFv3_RS14960 XRE family transcriptional regulator 0.23 RALBFv3_RS21855 heavy metal translocating P-type ATPase low > 76
Variovorax sp. OAS795 0.14 ABID97_RS13245 XRE family transcriptional regulator 0.26 ABID97_RS20715 heavy metal translocating P-type ATPase low > 91

Not shown: 16 genomes with orthologs for BWI76_RS10700 only; 24 genomes with orthologs for BWI76_RS26425 only