Conservation of cofitness between BWI76_RS20205 and BWI76_RS18935 in Klebsiella michiganensis M5al

38 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Klebsiella michiganensis M5al 1.0 BWI76_RS20205 aminotransferase AlaT 1.0 BWI76_RS18935 bifunctional imidazole glycerol-phosphate dehydratase/histidinol phosphatase 0.24 19
Enterobacter asburiae PDN3 0.98 EX28DRAFT_0319 Aspartate/tyrosine/aromatic aminotransferase 0.86 EX28DRAFT_0537 imidazoleglycerol-phosphate dehydratase (EC 4.2.1.19) low > 76
Enterobacter sp. TBS_079 0.98 MPMX20_03220 Glutamate-pyruvate aminotransferase AlaA 0.86 MPMX20_03004 Histidine biosynthesis bifunctional protein HisB 0.18 76
Escherichia coli BL21 0.97 ECD_02215 glutamate-pyruvate aminotransferase; glutamic-pyruvic transaminase (GPT); alanine transaminase 0.88 ECD_01924 histidinol-phosphatase and imidazoleglycerol-phosphate dehydratase low > 61
Escherichia coli ECOR38 0.97 HEPCGN_22030 alaA alanine transaminase AlaA 0.88 HEPCGN_03210 hisB bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB low > 87
Escherichia coli HS(pFamp)R (ATCC 700891) 0.97 OHPLBJKB_01415 Glutamate-pyruvate aminotransferase AlaA 0.88 OHPLBJKB_01678 Histidine biosynthesis bifunctional protein HisB low > 73
Escherichia coli Nissle 1917 0.97 ECOLIN_RS13295 alanine transaminase AlaA 0.88 ECOLIN_RS11955 bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB — —
Escherichia coli ECOR27 0.97 NOLOHH_14445 alaA alanine transaminase AlaA 0.88 NOLOHH_15820 hisB bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB low > 75
Escherichia coli ECRC62 0.97 BNILDI_13365 alaA alanine transaminase AlaA 0.88 BNILDI_14730 hisB bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB low > 75
Escherichia fergusonii Becca 0.97 EFB2_01568 Glutamate-pyruvate aminotransferase AlaA 0.88 EFB2_01834 Histidine biosynthesis bifunctional protein HisB low > 86
Escherichia coli BW25113 0.97 b2290 yfbQ aspartate aminotransferase (NCBI) 0.89 b2022 hisB imidazoleglycerolphosphate dehydratase and histidinol-phosphate phosphatase (VIMSS) 0.52 42
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.97 GFF1894 Aspartate aminotransferase (EC 2.6.1.1) 0.87 GFF3910 Histidinol-phosphatase (EC 3.1.3.15) / Imidazoleglycerol-phosphate dehydratase (EC 4.2.1.19) low > 78
Escherichia coli ECRC101 0.97 MCAODC_13865 alaA alanine transaminase AlaA 0.88 MCAODC_20435 hisB bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB low > 87
Escherichia coli ECRC98 0.97 JDDGAC_26790 alaA alanine transaminase AlaA 0.88 JDDGAC_28615 hisB bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB low > 86
Escherichia coli ECRC99 0.97 KEDOAH_05370 alaA alanine transaminase AlaA 0.88 KEDOAH_03645 hisB bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB — —
Escherichia coli ECRC100 0.97 OKFHMN_22825 alaA alanine transaminase AlaA 0.88 OKFHMN_24505 hisB bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB low > 80
Escherichia coli ECRC102 0.97 NIAGMN_20595 alaA alanine transaminase AlaA 0.88 NIAGMN_22450 hisB bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB — —
Pantoea sp. MT58 0.93 IAI47_06350 pyridoxal phosphate-dependent aminotransferase 0.81 IAI47_07080 bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB low > 76
Dickeya dadantii 3937 0.92 DDA3937_RS14345 pyridoxal phosphate-dependent aminotransferase 0.82 DDA3937_RS09725 bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB low > 74
Dickeya dianthicola ME23 0.92 DZA65_RS14995 pyridoxal phosphate-dependent aminotransferase 0.82 DZA65_RS10045 bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB low > 75
Serratia liquefaciens MT49 0.92 IAI46_17720 pyridoxal phosphate-dependent aminotransferase 0.84 IAI46_08200 bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB low > 86
Dickeya dianthicola 67-19 0.92 HGI48_RS14320 pyridoxal phosphate-dependent aminotransferase 0.81 HGI48_RS09735 bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB low > 71
Erwinia tracheiphila SCR3 0.91 LU632_RS07955 pyridoxal phosphate-dependent aminotransferase 0.81 LU632_RS08935 hisB bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB low > 74
Pectobacterium carotovorum WPP14 0.91 HER17_RS07115 pyridoxal phosphate-dependent aminotransferase 0.83 HER17_RS12240 bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB low > 75
Rahnella sp. WP5 0.88 EX31_RS19445 pyridoxal phosphate-dependent aminotransferase 0.83 EX31_RS11450 bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB 0.62 14
Vibrio cholerae E7946 ATCC 55056 0.80 CSW01_09870 pyridoxal phosphate-dependent aminotransferase 0.68 CSW01_05760 bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase low > 62
Shewanella loihica PV-4 0.74 Shew_1914 aminotransferase AlaT (RefSeq) 0.65 Shew_2200 imidazole glycerol-phosphate dehydratase/histidinol phosphatase (RefSeq) 0.38 52
Shewanella oneidensis MR-1 0.74 SO2483 aspartate aminotransferase, putative (NCBI ptt file) 0.62 SO2071 hisB imidazoleglycerol-phosphate dehydratase/histidinol-phosphatase (NCBI ptt file) low > 76
Shewanella sp. ANA-3 0.73 Shewana3_2145 aminotransferase AlaT (RefSeq) 0.62 Shewana3_1851 imidazole glycerol-phosphate dehydratase/histidinol phosphatase (RefSeq) low > 73
Shewanella amazonensis SB2B 0.73 Sama_1697 aminotransferase AlaT (RefSeq) 0.63 Sama_1944 imidazole glycerol-phosphate dehydratase/histidinol phosphatase (RefSeq) low > 62
Alteromonas macleodii MIT1002 0.67 MIT1002_02306 Glutamate-pyruvate aminotransferase AlaA 0.65 MIT1002_02635 Histidine biosynthesis bifunctional protein HisB 0.71 56
Pontibacter actiniarum KMM 6156, DSM 19842 0.60 CA264_06065 aminotransferase 0.46 CA264_05040 bifunctional imidazole glycerol-phosphate dehydratase/histidinol phosphatase low > 74
Lysobacter sp. OAE881 0.43 ABIE51_RS18840 aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme 0.53 ABIE51_RS13315 bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB 0.59 8
Rhodanobacter sp. FW510-T8 0.39 OKGIIK_12720 aspB aminotransferase 0.49 OKGIIK_04960 hisB bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB low > 52
Xanthomonas campestris pv. campestris strain 8004 0.39 Xcc-8004.1010.1 Aspartate aminotransferase (EC 2.6.1.1) 0.52 Xcc-8004.2946.1 Histidinol-phosphatase (EC 3.1.3.15) / Imidazoleglycerol-phosphate dehydratase (EC 4.2.1.19) 0.86 17
Rhodanobacter denitrificans FW104-10B01 0.39 LRK54_RS11155 aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme 0.49 LRK54_RS01595 bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB low > 59
Rhodanobacter denitrificans MT42 0.39 LRK55_RS10860 aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme 0.50 LRK55_RS01375 bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB low > 63
Dyella japonica UNC79MFTsu3.2 0.39 ABZR86_RS12435 aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme 0.50 ABZR86_RS06720 bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB 0.74 29
Mucilaginibacter yixingensis YX-36 DSM 26809 0.15 ABZR88_RS12100 pyridoxal phosphate-dependent aminotransferase 0.44 ABZR88_RS06870 bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB 0.61 40

Not shown: 35 genomes with orthologs for BWI76_RS20205 only; 8 genomes with orthologs for BWI76_RS18935 only