Conservation of cofitness between BWI76_RS04245 and BWI76_RS04680 in Klebsiella michiganensis M5al

37 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Klebsiella michiganensis M5al 1.0 BWI76_RS04245 bifunctional aspartate kinase/homoserine dehydrogenase I 1.0 BWI76_RS04680 2-isopropylmalate synthase 0.94 10
Escherichia coli BW25113 0.92 b0002 thrA bifunctional aspartokinase I/homeserine dehydrogenase I (NCBI) 0.95 b0074 leuA 2-isopropylmalate synthase (NCBI) 0.91 34
Escherichia coli ECOR38 0.92 HEPCGN_09115 thrA bifunctional aspartate kinase/homoserine dehydrogenase I 0.95 HEPCGN_08695 2-isopropylmalate synthase 0.96 16
Escherichia coli ECRC98 0.92 JDDGAC_14705 thrA bifunctional aspartate kinase/homoserine dehydrogenase I 0.94 JDDGAC_14310 2-isopropylmalate synthase 0.94 14
Escherichia coli ECRC100 0.92 OKFHMN_11110 thrA bifunctional aspartate kinase/homoserine dehydrogenase I 0.94 OKFHMN_10715 2-isopropylmalate synthase 0.99 7
Escherichia fergusonii Becca 0.92 EFB2_04041 Bifunctional aspartokinase/homoserine dehydrogenase 1 0.94 EFB2_03971 2-isopropylmalate synthase low > 86
Escherichia coli ECRC101 0.92 MCAODC_01625 thrA bifunctional aspartate kinase/homoserine dehydrogenase I 0.94 MCAODC_01230 2-isopropylmalate synthase 0.81 34
Escherichia coli ECRC102 0.92 NIAGMN_08960 thrA bifunctional aspartate kinase/homoserine dehydrogenase I 0.94 NIAGMN_08565 2-isopropylmalate synthase — —
Escherichia coli ECRC99 0.92 KEDOAH_17045 thrA bifunctional aspartate kinase/homoserine dehydrogenase I 0.94 KEDOAH_17440 2-isopropylmalate synthase — —
Escherichia coli ECOR27 0.92 NOLOHH_03440 thrA bifunctional aspartate kinase/homoserine dehydrogenase I 0.95 NOLOHH_03060 2-isopropylmalate synthase 0.92 33
Escherichia coli ECRC62 0.92 BNILDI_08160 thrA bifunctional aspartate kinase/homoserine dehydrogenase I 0.95 BNILDI_08550 2-isopropylmalate synthase 0.98 16
Escherichia coli HS(pFamp)R (ATCC 700891) 0.92 OHPLBJKB_03658 Bifunctional aspartokinase/homoserine dehydrogenase 1 0.95 OHPLBJKB_03583 2-isopropylmalate synthase 0.42 60
Escherichia coli BL21 0.92 ECD_00002 Bifunctional aspartokinase/homoserine dehydrogenase 1 0.95 ECD_00076 2-isopropylmalate synthase 0.96 13
Escherichia coli Nissle 1917 0.92 ECOLIN_RS00010 bifunctional aspartate kinase/homoserine dehydrogenase I 0.95 ECOLIN_RS00400 2-isopropylmalate synthase low > 55
Enterobacter sp. TBS_079 0.90 MPMX20_00710 Bifunctional aspartokinase/homoserine dehydrogenase 1 0.95 MPMX20_00769 2-isopropylmalate synthase 0.93 19
Enterobacter asburiae PDN3 0.89 EX28DRAFT_3614 aspartate kinase (EC 2.7.2.4) 0.96 EX28DRAFT_3670 2-isopropylmalate synthase (EC 2.3.3.13) low > 76
Rahnella sp. WP5 0.85 EX31_RS03945 bifunctional aspartate kinase/homoserine dehydrogenase I 0.82 EX31_RS03680 2-isopropylmalate synthase 0.96 38
Pantoea sp. MT58 0.84 IAI47_16215 bifunctional aspartate kinase/homoserine dehydrogenase I 0.83 IAI47_16000 2-isopropylmalate synthase 0.97 7
Serratia liquefaciens MT49 0.84 IAI46_03030 bifunctional aspartate kinase/homoserine dehydrogenase I 0.85 IAI46_03355 2-isopropylmalate synthase 0.72 43
Pectobacterium carotovorum WPP14 0.83 HER17_RS02795 bifunctional aspartate kinase/homoserine dehydrogenase I 0.87 HER17_RS03085 2-isopropylmalate synthase 0.94 20
Erwinia tracheiphila SCR3 0.83 LU632_RS02610 thrA bifunctional aspartate kinase/homoserine dehydrogenase I 0.85 LU632_RS02880 leuA 2-isopropylmalate synthase 0.87 6
Dickeya dadantii 3937 0.80 DDA3937_RS18415 bifunctional aspartate kinase/homoserine dehydrogenase I 0.86 DDA3937_RS18115 2-isopropylmalate synthase 0.80 50
Dickeya dianthicola ME23 0.80 DZA65_RS19485 bifunctional aspartate kinase/homoserine dehydrogenase I 0.86 DZA65_RS19200 2-isopropylmalate synthase 0.88 10
Dickeya dianthicola 67-19 0.80 HGI48_RS18345 bifunctional aspartate kinase/homoserine dehydrogenase I 0.86 HGI48_RS18055 2-isopropylmalate synthase 0.89 3
Vibrio cholerae E7946 ATCC 55056 0.62 CSW01_11975 bifunctional aspartate kinase/homoserine dehydrogenase I 0.68 CSW01_12595 2-isopropylmalate synthase low > 62
Shewanella loihica PV-4 0.57 Shew_1079 thrA bifunctional aspartokinase I/homeserine dehydrogenase I (RefSeq) 0.66 Shew_3472 2-isopropylmalate synthase (RefSeq) 0.99 3
Shewanella oneidensis MR-1 0.56 SO3415 thrA aspartokinase I/homoserine dehydrogenase, threonine-sensitive (NCBI ptt file) 0.66 SO4236 leuA 2-isopropylmalate synthase (NCBI ptt file) 0.85 20
Shewanella sp. ANA-3 0.56 Shewana3_1139 thrA bifunctional aspartokinase I/homeserine dehydrogenase I (RefSeq) 0.66 Shewana3_3761 2-isopropylmalate synthase (RefSeq) 0.92 23
Alteromonas macleodii MIT1002 0.53 MIT1002_03086 Aspartokinase I/homoserine dehydrogenase I 0.62 MIT1002_00949 2-isopropylmalate synthase 0.96 38
Shewanella amazonensis SB2B 0.53 Sama_0905 thrA bifunctional aspartokinase I/homeserine dehydrogenase I (RefSeq) 0.66 Sama_0335 2-isopropylmalate synthase (RefSeq) 0.88 47
Xanthomonas campestris pv. campestris strain 8004 0.33 Xcc-8004.2957.1 Aspartokinase (EC 2.7.2.4) / Homoserine dehydrogenase (EC 1.1.1.3) 0.38 Xcc-8004.1056.1 2-isopropylmalate synthase (EC 2.3.3.13) 0.72 57
Phocaeicola vulgatus CL09T03C04 0.32 HMPREF1058_RS14720 bifunctional aspartate kinase/homoserine dehydrogenase I 0.43 HMPREF1058_RS14545 2-isopropylmalate synthase 0.92 17
Phocaeicola dorei CL03T12C01 0.32 ABI39_RS10430 bifunctional aspartate kinase/homoserine dehydrogenase I 0.43 ABI39_RS10195 2-isopropylmalate synthase 0.85 24
Parabacteroides merdae CL09T00C40 0.31 HMPREF1078_RS10385 bifunctional aspartate kinase/homoserine dehydrogenase I 0.43 HMPREF1078_RS16665 2-isopropylmalate synthase 0.93 49
Lysobacter sp. OAE881 0.30 ABIE51_RS17520 bifunctional aspartate kinase/homoserine dehydrogenase I 0.39 ABIE51_RS17570 2-isopropylmalate synthase low > 62
Bacteroides stercoris CC31F 0.28 HMPREF1181_RS00060 bifunctional aspartate kinase/homoserine dehydrogenase I 0.42 HMPREF1181_RS14150 2-isopropylmalate synthase 0.93 27
Bacteroides thetaiotaomicron VPI-5482 0.28 BT2403 aspartate kinase / homoserine dehydrogenase (EC 2.7.2.4; EC 1.1.1.3) (from data) 0.42 BT1861 2-isopropylmalate synthase (EC 2.3.3.13) (from data) 0.84 23
Bacteroides ovatus ATCC 8483 0.28 BACOVA_03021 homoserine dehydrogenase 0.42 BACOVA_04604 2-isopropylmalate synthase 0.96 10

Not shown: 4 genomes with orthologs for BWI76_RS04245 only; 35 genomes with orthologs for BWI76_RS04680 only