Conservation of cofitness between A4249_RS00615 and A4249_RS09675 in Brevundimonas sp. GW460-12-10-14-LB2

45 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Brevundimonas sp. GW460-12-10-14-LB2 1.0 A4249_RS00615 threonine ammonia-lyase, biosynthetic 1.0 A4249_RS09675 siroheme synthase CysG 0.99 3
Pseudomonas stutzeri RCH2 0.58 Psest_3866 threonine ammonia-lyase, biosynthetic, long form 0.41 Psest_2037 uroporphyrin-III C-methyltransferase low > 67
Castellaniella sp019104865 MT123 0.58 ABCV34_RS14460 threonine ammonia-lyase, biosynthetic 0.34 ABCV34_RS00210 siroheme synthase CysG low > 48
Pseudomonas sp. S08-1 0.56 OH686_11400 threonine ammonia-lyase, biosynthetic 0.38 OH686_00285 Precorrin-2 oxidase or Sirohydrochlorin ferrochelatase activity of CysG / Uroporphyrinogen-III methyltransferase low > 80
Pseudomonas fluorescens FW300-N2E3 0.56 AO353_08485 threonine dehydratase 0.40 AO353_27625 sirohydrochlorin ferrochelatase — —
Pseudomonas fluorescens GW456-L13 0.55 PfGW456L13_949 Threonine dehydratase biosynthetic (EC 4.3.1.19) 0.39 PfGW456L13_2656 Siroheme synthase / Precorrin-2 oxidase (EC 1.3.1.76) / Sirohydrochlorin ferrochelatase (EC 4.99.1.4) / Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) 0.76 5
Pseudomonas putida KT2440 0.55 PP_5149 threonine deaminase 0.38 PP_3999 Uroporphyrinogen-III C-methyltransferase/Precorrin-2 dehydrogenase/Sirohydrochlorin ferrochelatase 0.19 39
Pseudomonas fluorescens SBW25 0.55 PFLU_RS28665 threonine ammonia-lyase, biosynthetic 0.40 PFLU_RS18505 uroporphyrinogen-III C-methyltransferase low > 109
Pseudomonas fluorescens SBW25-INTG 0.55 PFLU_RS28665 threonine ammonia-lyase, biosynthetic 0.40 PFLU_RS18505 uroporphyrinogen-III C-methyltransferase 0.40 20
Pseudomonas fluorescens FW300-N2E2 0.55 Pf6N2E2_3938 Threonine dehydratase biosynthetic (EC 4.3.1.19) 0.40 Pf6N2E2_302 Siroheme synthase / Precorrin-2 oxidase (EC 1.3.1.76) / Sirohydrochlorin ferrochelatase (EC 4.99.1.4) / Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) 0.49 52
Pseudomonas fluorescens FW300-N1B4 0.55 Pf1N1B4_2280 Threonine dehydratase biosynthetic (EC 4.3.1.19) 0.39 Pf1N1B4_4065 Siroheme synthase / Precorrin-2 oxidase (EC 1.3.1.76) / Sirohydrochlorin ferrochelatase (EC 4.99.1.4) / Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) 0.79 10
Pseudomonas fluorescens FW300-N2C3 0.54 AO356_10330 threonine dehydratase 0.39 AO356_22200 sirohydrochlorin ferrochelatase 0.68 30
Pseudomonas sp. RS175 0.54 PFR28_04834 L-threonine dehydratase biosynthetic IlvA 0.39 PFR28_02603 Siroheme synthase 0.58 13
Pseudomonas simiae WCS417 0.54 PS417_27010 threonine dehydratase 0.40 PS417_16465 sirohydrochlorin ferrochelatase 0.60 38
Pseudomonas syringae pv. syringae B728a 0.54 Psyr_4846 L-threonine ammonia-lyase 0.40 Psyr_3174 uroporphyrinogen-III C-methyltransferase / precorrin-2 dehydrogenase low > 86
Pseudomonas syringae pv. syringae B728a ΔmexB 0.54 Psyr_4846 L-threonine ammonia-lyase 0.40 Psyr_3174 uroporphyrinogen-III C-methyltransferase / precorrin-2 dehydrogenase low > 86
Dickeya dadantii 3937 0.53 DDA3937_RS20150 threonine ammonia-lyase, biosynthetic 0.34 DDA3937_RS16930 uroporphyrinogen-III C-methyltransferase 0.83 23
Dickeya dianthicola 67-19 0.53 HGI48_RS20290 threonine ammonia-lyase, biosynthetic 0.35 HGI48_RS17000 uroporphyrinogen-III C-methyltransferase low > 71
Escherichia coli ECOR38 0.51 HEPCGN_13345 ilvA threonine ammonia-lyase, biosynthetic 0.35 HEPCGN_16010 cysG siroheme synthase CysG 0.96 13
Escherichia coli ECRC62 0.51 BNILDI_04755 ilvA threonine ammonia-lyase, biosynthetic 0.36 BNILDI_02540 cysG siroheme synthase CysG 0.96 40
Escherichia coli BL21 0.51 ECD_03650 l-threonine dehydratase, biosynthetic; also known as threonine deaminase 0.35 ECD_03219 fused siroheme synthase 1,3-dimethyluroporphyriongen III dehydrogenase and siroheme ferrochelatase/uroporphyrinogen methyltransferase 0.68 55
Escherichia coli ECOR27 0.51 NOLOHH_06770 ilvA threonine ammonia-lyase, biosynthetic 0.36 NOLOHH_08980 cysG siroheme synthase CysG 0.87 48
Escherichia coli ECRC99 0.51 KEDOAH_13515 ilvA threonine ammonia-lyase, biosynthetic 0.35 KEDOAH_10960 cysG siroheme synthase CysG — —
Escherichia coli BW25113 0.51 b3772 ilvA threonine dehydratase (NCBI) 0.35 b3368 cysG fused siroheme synthase 1,3-dimethyluroporphyriongen III dehydrogenase and siroheme ferrochelatase/uroporphyrinogen methyltransferase (NCBI) 0.94 19
Escherichia coli ECRC102 0.51 NIAGMN_12390 ilvA threonine ammonia-lyase, biosynthetic 0.35 NIAGMN_14950 cysG siroheme synthase CysG — —
Escherichia coli ECRC101 0.51 MCAODC_05140 ilvA threonine ammonia-lyase, biosynthetic 0.35 MCAODC_07710 cysG siroheme synthase CysG 0.73 66
Escherichia coli HS(pFamp)R (ATCC 700891) 0.51 OHPLBJKB_04281 L-threonine dehydratase biosynthetic IlvA 0.35 OHPLBJKB_00334 Siroheme synthase low > 73
Escherichia coli ECRC100 0.51 OKFHMN_14635 ilvA threonine ammonia-lyase, biosynthetic 0.35 OKFHMN_17180 cysG siroheme synthase CysG 0.98 29
Escherichia coli ECRC98 0.51 JDDGAC_18255 ilvA threonine ammonia-lyase, biosynthetic 0.35 JDDGAC_20810 cysG siroheme synthase CysG low > 86
Klebsiella michiganensis M5al 0.51 BWI76_RS00980 PLP-dependent threonine dehydratase 0.35 BWI76_RS26055 siroheme synthase 0.82 48
Escherichia fergusonii Becca 0.51 EFB2_04864 L-threonine dehydratase biosynthetic IlvA 0.35 EFB2_00454 Siroheme synthase low > 86
Escherichia coli Nissle 1917 0.51 ECOLIN_RS21670 threonine ammonia-lyase, biosynthetic 0.35 ECOLIN_RS19285 siroheme synthase CysG 0.91 2
Enterobacter asburiae PDN3 0.50 EX28DRAFT_4444 threonine ammonia-lyase, biosynthetic, long form 0.36 EX28DRAFT_2849 uroporphyrin-III C-methyltransferase 0.74 34
Rhodanobacter sp. FW510-T8 0.50 OKGIIK_13620 ilvA threonine ammonia-lyase, biosynthetic 0.33 OKGIIK_05980 cysG siroheme synthase CysG low > 52
Erwinia tracheiphila SCR3 0.50 LU632_RS24395 ilvA threonine ammonia-lyase, biosynthetic 0.37 LU632_RS06420 cysG siroheme synthase CysG 0.91 15
Pantoea sp. MT58 0.50 IAI47_01040 threonine ammonia-lyase, biosynthetic 0.38 IAI47_04175 uroporphyrinogen-III C-methyltransferase 0.83 56
Enterobacter sp. TBS_079 0.50 MPMX20_04498 L-threonine dehydratase biosynthetic IlvA 0.36 MPMX20_03639 Siroheme synthase low > 85
Serratia liquefaciens MT49 0.50 IAI46_24340 threonine ammonia-lyase, biosynthetic 0.37 IAI46_23670 uroporphyrinogen-III C-methyltransferase low > 86
Dickeya dianthicola ME23 0.50 DZA65_RS21330 threonine ammonia-lyase, biosynthetic 0.35 DZA65_RS18075 uroporphyrinogen-III C-methyltransferase 0.84 33
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.50 GFF2900 Threonine dehydratase biosynthetic (EC 4.3.1.19) 0.36 GFF3700 Siroheme synthase / Precorrin-2 oxidase (EC 1.3.1.76) / Sirohydrochlorin ferrochelatase (EC 4.99.1.4) / Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) low > 78
Pectobacterium carotovorum WPP14 0.49 HER17_RS01080 threonine ammonia-lyase, biosynthetic 0.38 HER17_RS01835 siroheme synthase CysG low > 75
Rahnella sp. WP5 0.49 EX31_RS15010 threonine ammonia-lyase, biosynthetic 0.37 EX31_RS07885 uroporphyrinogen-III C-methyltransferase 0.85 61
Rhodanobacter denitrificans FW104-10B01 0.48 LRK54_RS10300 threonine ammonia-lyase, biosynthetic 0.32 LRK54_RS00910 siroheme synthase CysG 0.29 29
Rhodanobacter denitrificans MT42 0.48 LRK55_RS09940 threonine ammonia-lyase, biosynthetic 0.31 LRK55_RS00685 siroheme synthase CysG low > 63
Alteromonas macleodii MIT1002 0.47 MIT1002_04040 L-threonine dehydratase biosynthetic IlvA 0.39 MIT1002_00665 Siroheme synthase — —
Acinetobacter radioresistens SK82 0.45 MPMX26_01278 L-threonine dehydratase biosynthetic IlvA 0.38 MPMX26_00706 Siroheme synthase — —

Not shown: 23 genomes with orthologs for A4249_RS00615 only; 8 genomes with orthologs for A4249_RS09675 only